Research Topics
| A KelSummaryAffiliation: BIOBASE GmbH Country: Germany Publications
| Collaborators
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Detail Information
Publications
Computer-assisted identification of cell cycle-related genes: new targets for E2F transcription factorsA E Kel
Institute of Cytology and Genetics, Novosibirsk, Russia
J Mol Biol 309:99-120. 2001..The tools described are available at http://compel.bionet.nsc.ru/FunSite/SiteScan.html...
MATCH: A tool for searching transcription factor binding sites in DNA sequencesA E Kel
BIOBASE GmbH, Halchtersche Str 33, D 38304 Wolfenbuttel, Germany
Nucleic Acids Res 31:3576-9. 2003..com/pub/programs.html#match. The same program with a different web interface can be found at http://compel.bionet.nsc.ru/Match/Match.html. An advanced version of the tool called Match Professional is available at http://www.biobase.de...
Recognition of multiple patterns in unaligned sets of sequences: comparison of kernel clustering method with other methodsA Kel
Institute of Cytology and Genetics SB RAN, Lavrentyev pr, 10, 630090, Novosibirsk, Russia
Bioinformatics 20:1512-6. 2004..Often one set of sites can contain several subsets of sequences that follow not just one but several different patterns. There is a need for sensitive methods to reveal multiple patterns in unaligned sets of sequences...
Genome wide prediction of HNF4alpha functional binding sites by the use of local and global sequence contextAlexander E Kel
BIOBASE GmbH, Halchtersche Str, 38304 Wolfenbüttel, Germany
Genome Biol 9:R36. 2008..When applied to published findings, an unprecedented high number of false positives were identified. The technique can be applied to any transcription factor...
A genetic algorithm for designing gene family-specific oligonucleotide sets used for hybridization: the G protein-coupled receptor protein superfamilyA Kel
Institute of Cytology and Genetics, pr Lavrentyeva 10, 630090, Novosibirsk, Russia
Bioinformatics 14:259-70. 1998..The critical point is to design appropriate sets of oligonucleotides that can be used effectively in identification by hybridization...
Recognition of NFATp/AP-1 composite elements within genes induced upon the activation of immune cellsA Kel
Institute of Cytology and Genetics, pr Lavrentyeva 10, 630090, Novosibirsk, Russia
J Mol Biol 288:353-76. 1999..The program for recognition NFAT composite elements is available through the World Wide Web (http://compel.bionet.nsc.ru/FunSite/CompelScan. html and http://transfac.gbf.de/dbsearch/funsitep/s _comp.html)...
Composite Module Analyst: a fitness-based tool for identification of transcription factor binding site combinationsA Kel
BIOBASE GmbH Halchtersche Str 33, D 38304 Wolfenbuttel, Germany
Bioinformatics 22:1190-7. 2006..Cis-element combinations provide a structural basis for the generation of unique patterns of gene expression...
ExPlain: finding upstream drug targets in disease gene regulatory networksA Kel
BIOBASE GmbH, Wolfenbüttel, Germany
SAR QSAR Environ Res 19:481-94. 2008..ExPlain system was applied to microarray data on inflammatory bowel diseases (IBD). The results obtained suggest a number of highly interesting biological hypotheses about molecular mechanisms of pathological genetic disregulation...
3DTF: a web server for predicting transcription factor PWMs using 3D structure-based energy calculationsR Gabdoulline
Heinrich Heine University of Duesseldorf, Universitaetstr 1, 40225 Duesseldorf, Germany
Nucleic Acids Res 40:W180-5. 2012..The webserver can be used by biologists to derive novel PWMs for transcription factors lacking known binding sites and is freely accessible at http://www.gene-regulation.com/pub/programs/3dtf/...
Composite Module Analyst: identification of transcription factor binding site combinations using genetic algorithmT Waleev
A.P. Ershov's Institute of Informatics Systems 6, Lavrentiev Avenue, 630090 Novosibirsk, Russia
Nucleic Acids Res 34:W541-5. 2006..gene-regulation.com/pub/programs/cma/CMA.html. An advanced version of CMA is also a part of the commercial system ExPlaintrade mark (www.biobase.de) designed for causal analysis of gene expression data...
Human versus chimpanzee chromosome-wide sequence comparison and its evolutionary implicationY Sakaki
RIKEN, Genomic Sciences Center, Yokohama 230-0045, Japan
Cold Spring Harb Symp Quant Biol 68:455-60. 2003
