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Species | F BinkofskiSummaryCountry: Germany Publications
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Publications
[Apraxias]F Binkofski
Klinik und Poliklinik für Neurologie und Neuroimage Nord, Universitätskrankenhaus Schleswig Holstein, Campus Lubeck, Deutschland
Nervenarzt 76:493-509; quiz 510-1. 2005..Therefore, appropriate diagnosis and treatment of the different forms are of foremost clinical importance...- The role of ventral premotor cortex in action execution and action understandingFerdinand Binkofski
Department of Neurology and Neuroimage Nord, University Hospital Schleswig Holstein, Campus Luebeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
J Physiol Paris 99:396-405. 2006..Experimental evidence in favour of this hypothesis both in the monkey and humans is shortly reviewed... - Morphometric fingerprint of asymptomatic Parkin and PINK1 mutation carriers in the basal gangliaF Binkofski
Department of Neurology, University Hospital Schleswig Holstein, Campus Luebeck, Luebeck, Germany
Neurology 69:842-50. 2007..We hypothesized that subclinical nigrostriatal neurodegeneration caused by these mutations would induce morphologic changes in the dysfunctional striatal gray matter... 
Heterozygous carriers of a Parkin or PINK1 mutation share a common functional endophenotypeB F L van Nuenen
Department of Neurology, Christian Albrechts University, Kiel, Germany
Neurology 72:1041-7. 2009..Specifically, we examined how a single heterozygous mutation in different genes associated with recessively inherited Parkinson disease alters the cortical control of sequential finger movements...- A fronto-parietal circuit for object manipulation in man: evidence from an fMRI-studyF Binkofski
Department of Neurology, Heinrich Heine University of Dusseldorf, Germany
Eur J Neurosci 11:3276-86. 1999..It is proposed that area SII analyses the intrinsic object characteristics whilst the superior parietal lobule is related to kinaesthesia... 
Progression of subtle motor signs in PINK1 mutation carriers with mild dopaminergic deficitC Eggers
Department of Neurology, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
Neurology 74:1798-805. 2010..While homozygous mutations in the PINK1 gene cause recessively inherited early-onset Parkinson disease (PD), heterozygous mutations have been suggested as a susceptibility factor...- The role of diaschisis in stroke recoveryR J Seitz
Department of Neurology, Heinrich Heine University Dusseldorf, Germany
Stroke 30:1844-50. 1999..To address this question, we studied regional cerebral blood flow in 7 patients (mean+/-SD age, 54+/-8 years) after their first hemiparetic stroke... - Role of the premotor cortex in recovery from middle cerebral artery infarctionR J Seitz
Department of Neurology, Heinrich Heine University Dusseldorf, Germany
Arch Neurol 55:1081-8. 1998..To study the mechanisms underlying recovery from middle cerebral artery infarction in 7 patients with an average age of 53 years who showed marked recovery of hand function after acute severe hemiparesis caused by their first-ever stroke... - Activation of frontoparietal cortices during memorized triple-step sequences of saccadic eye movements: an fMRI studyW Heide
Department of Neurology, Medical University at Lubeck, D 23538 Lubeck, Germany
Eur J Neurosci 13:1177-89. 2001.... - Neural activity related to self- versus externally generated painful stimuli reveals distinct differences in the lateral pain system in a parametric fMRI studyChristoph Helmchen
NeuroImage Nord, Department of Neurology, University of Lubeck, Lubeck, Germany
Hum Brain Mapp 27:755-65. 2006..The attenuated activation of SI during self-generated painful stimulation might be a result of the predictability of the sensory consequences of the pain-related action... - Reduced neuronal activity in the V5 complex underlies smooth-pursuit deficit in schizophrenia: evidence from an fMRI studyRebekka Lencer
Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
Neuroimage 24:1256-9. 2005.... - Cortical mechanisms of smooth pursuit eye movements with target blanking. An fMRI studyRebekka Lencer
Department of Psychiatry and Psychotherapy, University of Leubeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
Eur J Neurosci 19:1430-6. 2004.... - Recovery of motor functions following hemiparetic stroke: a clinical and magnetic resonance-morphometric studyF Binkofski
Department of Neurology, Heinrich Heine University of Dusseldorf, Germany
Cerebrovasc Dis 11:273-81. 2001..Since lesion size was not correlated with outcome the amount of spared residual function appeared as major determinant for the capacity for motor recovery... - Control of action as mediated by the human frontal lobeR J Seitz
Department of Neurology, Heinrich Heine University Dusseldorf, Germany
Exp Brain Res 133:71-80. 2000..It is suggested that the initiational aspects of conscious motor activity are implemented in a medial system of information flow and the integrative aspects in a lateral system of the human frontal lobe... - Parametric modulation of cortical activation during smooth pursuit with and without target blanking. an fMRI studyMatthias Nagel
Department of Psychiatry and Psychotherapy, University of Luebeck, Luebeck, Germany
Neuroimage 29:1319-25. 2006..Furthermore, we suggest that parietal areas are related to the suppression of saccades during smooth pursuit... - Motor impairment in patients with parietal lesions: disturbances of meaningless arm movement sequencesP H Weiss
Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
Neuropsychologia 39:397-405. 2001..These results demonstrate that lesions in the left parietal lobe lead to a disturbed spatio-temporal organisation of movement that becomes increasingly prominent for more complex movements... - The role of ipsilateral primary motor cortex in movement control and recovery from brain damageM C Stoeckel
Department of Neurology, University of Lubeck, Germany
Exp Neurol 221:13-7. 2010..This comment briefly summarizes the relevant findings supporting both views and discusses potential causes for the prima facie contradictory findings... - Tactile apraxia: unimodal apractic disorder of tactile object exploration associated with parietal lobe lesionsF Binkofski
Department of Neurology, Heinrich-Heine-University, , Germany
Brain 124:132-44. 2001.... - The anterior cingulate cortex contains distinct areas dissociating external from self-administered painful stimulation: a parametric fMRI studyC Mohr
NeuroImage Nord (NIN, Department of Neurology, , Ratzeburger Allee 160, , Germany
Pain 114:347-57. 2005.... - Left and right superior parietal lobule in tactile object discriminationM C Stoeckel
Department of Neurology, , , Germany
Eur J Neurosci 19:1067-72. 2004.... - Cerebellar neural responses related to actively and passively applied noxious thermal stimulation in human subjects: a parametric fMRI studyC Helmchen
Department of Neurology, University of Luebeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
Neurosci Lett 361:237-40. 2004..The cerebellum seems to be capable of distinguishing active from passive painful stimuli... - Cortical mechanisms of retinal and extraretinal smooth pursuit eye movements to different target velocitiesMatthias Nagel
Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
Neuroimage 41:483-92. 2008..The activation of the inferior parietal cortex seems to be related to the interaction between velocity and blanking thereby underlining its relevance for task switching and sensorimotor transformation... - Dissociating networks of imitationMareike M Menz
Department of Neurology and Neuroimage Nord, University Hospital Schleswig Holstein, Campus Luebeck, Germany
Hum Brain Mapp 30:3339-50. 2009..This indicates a late integration of object affordances into the movement as the time course of activity in this network pertains to action rather than perception of the object... - Functional properties and interaction of the anterior and posterior intraparietal areas in humansElisa Shikata
Cognitive Neuroscience Laboratory, Department of Neurology, Hamburg University School of Medicine, Martinstrasse 52, D-20246 Hamburg, Germany
Eur J Neurosci 17:1105-10. 2003..These data clearly indicate that the function of human CIP is more involved in coding 3D features of the objects, whereas human AIP is more involved in visually guided hand movements, similar to its role in the monkey... - Action observation has a positive impact on rehabilitation of motor deficits after strokeDenis Ertelt
Department of Neurology and Neuroimage Nord, University Hospital Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
Neuroimage 36:T164-73. 2007.... - Modular organization of parietal lobe functions as revealed by functional activation studiesRudiger J Seitz
Department of Neurology, University Hospital Dusseldorf, Dusseldorf, Germany
Adv Neurol 93:281-92. 2003 - Increased functional connectivity is crucial for learning novel muscle synergiesAdam McNamara
NeuroImage Nord, Department of Neurology, University Hospital Schleswig Holstein, Campus Luebeck, Ratzeburger Allee 160, UKSH Luebeck, 23539, Germany
Neuroimage 35:1211-8. 2007..Greater levels of daily activity may increase the integration of muscle representations across the motor cortex, enabling faster learning of novel movements... - Limbic and frontal cortical degeneration is associated with psychiatric symptoms in PINK1 mutation carriersKathrin Reetz
Department of Neurology, University of Luebeck, Luebeck, Germany
Biol Psychiatry 64:241-7. 2008..Mutations in the PINK1 gene can cause Parkinson's disease and are frequently associated with psychiatric symptoms that might even precede motor signs... - Modulation of the BOLD-response in early recovery from sensorimotor strokeFerdinand Binkofski
Department of Neurology, University Hospital Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, 23539 Lübeck, Germany
Neurology 63:1223-9. 2004..The BOLD signal in functional MRI (fMRI) is closely related to neural activity... - Different extraretinal neuronal mechanisms of smooth pursuit eye movements in schizophrenia: An fMRI studyMatthias Nagel
Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
Neuroimage 34:300-9. 2007..The results implicate that schizophrenic patients employ different strategies during SPEM both with and without target blanking than healthy subjects. These strategies predominantly involve extraretinal mechanisms... - A fronto-parietal circuit for tactile object discrimination: an event-related fMRI studyM Cornelia Stoeckel
Department of Neurology, University Hospital Dusseldorf, Dusseldorf, Germany
Neuroimage 19:1103-14. 2003..The results reveal a prominent role of the human prefrontal cortex for somatosensory object discrimination in correspondence with recent models on stimulus discrimination and working memory... - Neural dynamics of learning sound-action associationsAdam McNamara
NeuroImage Nord, Department of Neurology, UKSH, Luebeck, Germany
PLoS ONE 3:e3845. 2008.... - Activation of cerebellar hemispheres in spatial memorization of saccadic eye movements: an fMRI studyMatthias F Nitschke
Department of Neurology, University Hospital Schleswig Holstein, Campus Lubeck, Lubeck, Germany
Hum Brain Mapp 22:155-64. 2004.... - Supramodal representation of objects and actions in the human inferior temporal and ventral premotor cortexFerdinand Binkofski
Dept. of Neurology, University Hospital Schleswig-Holstein, , Germany
Cortex 40:159-61. 2004 - Mirror apraxia affects the peripersonal mirror space. A combined lesion and cerebral activation studyFerdinand Binkofski
Department of Neurology, University Hospital Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
Exp Brain Res 153:210-9. 2003..The results demonstrate that acting through a mirror is processed in a number of cortical areas of the dorsal stream... - Introduction: higher motor cognition - from basic neuroscience to apraxiaFerdinand Binkofski
Neuroimage 36:T1. 2007 - The mirror neuron system and action recognitionGiovanni Buccino
Dipartimento di Neuroscienze, Sezione di Fisiologia, Universita di Parma, Via Volturno 39, 43100 Parma, Italy
Brain Lang 89:370-6. 2004..It has been proposed that this system is involved in action recognition. Experimental evidence in favor of this hypothesis both in the monkey and humans are shortly reviewed... - Clinical spectrum of homozygous and heterozygous PINK1 mutations in a large German family with Parkinson disease: role of a single hit?Katja Hedrich
Department of Neurology, University of Lubeck, Germany
Arch Neurol 63:833-8. 2006..Although homozygous mutations in the PTEN-induced putative kinase 1 (PINK1) gene have been unequivocally associated with early-onset Parkinson disease (PD), the role of single heterozygous PINK1 mutations is less clear... - Polymodal conceptual processing of human biological actions in the left inferior frontal lobeAnnette Baumgaertner
NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
Eur J Neurosci 25:881-9. 2007..We conclude that the pars opercularis of Broca's area is endowed with polymodal capabilities, allowing the processing of higher-level conceptual aspects of action understanding... - Localization of human intraparietal areas AIP, CIP, and LIP using surface orientation and saccadic eye movement tasksElisa Shikata
NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Germany
Hum Brain Mapp 29:411-21. 2008.... - Biological effects of the PINK1 c.1366C>T mutation: implications in Parkinson disease pathogenesisAnne Grünewald
Department of Neurology, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
Neurogenetics 8:103-9. 2007..1366C>T mutation... - Motor functions of the Broca's regionFerdinand Binkofski
Department of Neuroscience, Section of Physiology, University of Parma, Italy
Brain Lang 89:362-9. 2004..Brodmann's area 44 is also a part of a specialized parieto-premotor network and interacts significantly with the neighboring premotor areas... - A fronto-parietal network is mediating improvement of motor function related to repetitive peripheral magnetic stimulation: A PET-H2O15 studyAlbrecht Struppler
Sensorimotor Integration Research Group, Klinikum rechts der Isar der TUM, Psychiatrische Klinik 7 0, Ismaningerstr 22, 81675 Munchen, Germany
Neuroimage 36:T174-86. 2007..These results emphasize the positive therapeutic effect of RPMS and describe the physiological bases of its function on the central level... - [Which patients benefit?]Ferdinand Binkofski
MMW Fortschr Med 146:6. 2004 - The neural basis for understanding non-intended actionsGiovanni Buccino
Department of Neuroscience, Section of Physiology, University of Parma, Via Volturno 31, 43100 Parma, Italy
Neuroimage 36:T119-27. 2007..The concomitant activation of mesial prefrontal areas, known to be involved in self-referential processing, might reflect how deeply participants are involved in the observed scenes...