Daniel Besser

Summary

Country: Germany

Publications

  1. ncbi Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3
    Daniel Besser
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, New York 10021, USA
    J Biol Chem 279:45076-84. 2004
  2. ncbi Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization
    Christian Wolfrum
    Laboratories of Metabolic Diseases and Molecular Vertebrate Embryology, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 100:11624-9. 2003
  3. ncbi TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    Daylon James
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Development 132:1273-82. 2005
  4. ncbi Independent and cooperative activation of chromosomal c-fos promoter by STAT3
    Edward Yang
    Laboratory of Molecular Cell Biology, The Rockefeller University, New York, NY 10021, USA
    J Biol Chem 278:15794-9. 2003
  5. ncbi FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells
    Sebastian Diecke
    Max Delbruck Center, Berlin, Germany
    Cells Tissues Organs 188:52-61. 2008
  6. ncbi Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation
    Weimin L Kaufman
    Max Delbruck Center for Molecular Medicine, Robert Rossle Strasse 10, 13125 Berlin, Germany
    Nucleic Acids Res 36:e111. 2008

Collaborators

Detail Information

Publications6

  1. ncbi Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3
    Daniel Besser
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, New York 10021, USA
    J Biol Chem 279:45076-84. 2004
    ..Moreover, there appears to be cross-talk between inhibition of GSK3, a hallmark of Wnt signaling and the Activin/Nodal pathway...
  2. ncbi Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization
    Christian Wolfrum
    Laboratories of Metabolic Diseases and Molecular Vertebrate Embryology, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 100:11624-9. 2003
    ..These results implicate an evolutionarily conserved mechanism in the regulation of Foxa-2-dependent transcriptional control by extracellular signals such as insulin...
  3. ncbi TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    Daylon James
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Development 132:1273-82. 2005
    ..These data reveal a crucial role for TGFbeta signaling in the earliest stages of cell fate determination and demonstrate an interconnection between TGFbeta and WNT signaling in these contexts...
  4. ncbi Independent and cooperative activation of chromosomal c-fos promoter by STAT3
    Edward Yang
    Laboratory of Molecular Cell Biology, The Rockefeller University, New York, NY 10021, USA
    J Biol Chem 278:15794-9. 2003
    ..Thus the several proteins that interact with the c-fos enhancer apparently can act either in a cooperative or independent manner to achieve very different levels of transcription...
  5. ncbi FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells
    Sebastian Diecke
    Max Delbruck Center, Berlin, Germany
    Cells Tissues Organs 188:52-61. 2008
    ..This study identifies potentially important factors involved in the maintenance of pluripotency in hESCs and may allow the development of defined culture conditions without contaminating material from animal cells...
  6. ncbi Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation
    Weimin L Kaufman
    Max Delbruck Center for Molecular Medicine, Robert Rossle Strasse 10, 13125 Berlin, Germany
    Nucleic Acids Res 36:e111. 2008
    ..However, by combining this approach with site-specific recombination, it can be applied to isolate stable cell lines with the desired expression characteristics for any gene of interest...