Simone Korten

Summary

Affiliation: Bernhard Nocht Institute for Tropical Medicine
Country: Germany

Publications

  1. pmc Invariant Valpha14 chain NKT cells promote Plasmodium berghei circumsporozoite protein-specific gamma interferon- and tumor necrosis factor alpha-producing CD8+ T cells in the liver after poxvirus vaccination of mice
    Simone Korten
    Department of Immunology, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, 20359 Hamburg, Germany
    Infect Immun 73:849-58. 2005
  2. doi request reprint The nematode parasite Onchocerca volvulus generates the transforming growth factor-beta (TGF-beta)
    Simone Korten
    Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Str 74, 20359, Hamburg, Germany
    Parasitol Res 105:731-41. 2009
  3. doi request reprint Natural death of adult Onchocerca volvulus and filaricidal effects of doxycycline induce local FOXP3+/CD4+ regulatory T cells and granzyme expression
    Simone Korten
    Department of Immunology, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, D 20359 Hamburg, Germany
    Microbes Infect 10:313-24. 2008
  4. pmc Immunohistology of ectopic secondary lymph follicles in subcutaneous nodules from patients with hyperreactive onchocerciasis (sowda)
    Norbert W Brattig
    Department of Molecular Medicine, Bernhard Nocht Institute for Tropical Medicine BNI, Bernhard Nocht Str 74, Hamburg, Germany
    Parasitol Res 107:657-66. 2010
  5. ncbi request reprint Expansion of NK cells with reduction of their inhibitory Ly-49A, Ly-49C, and Ly-49G2 receptor-expressing subsets in a murine helminth infection: contribution to parasite control
    Simone Korten
    Department of Medical Microbiology and Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
    J Immunol 168:5199-206. 2002
  6. doi request reprint A novel and divergent role of granzyme A and B in resistance to helminth infection
    Wiebke Hartmann
    Department of Immunology, Bernhard Nocht Institute for Tropical Medicine, D 20359 Hamburg, Germany
    J Immunol 186:2472-81. 2011
  7. ncbi request reprint Enhanced CD8+ T cell immune responses and protection elicited against Plasmodium berghei malaria by prime boost immunization regimens using a novel attenuated fowlpox virus
    Richard J Anderson
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
    J Immunol 172:3094-100. 2004
  8. ncbi request reprint Modulation of Ly49 D expression after allogeneic bone marrow transplantation and functional consequences
    Esther Wilk
    Abteilung Klinische Immunologie, Medizinische Hochschule Hannover, Germany
    Immunobiology 205:267-81. 2002

Collaborators

Detail Information

Publications8

  1. pmc Invariant Valpha14 chain NKT cells promote Plasmodium berghei circumsporozoite protein-specific gamma interferon- and tumor necrosis factor alpha-producing CD8+ T cells in the liver after poxvirus vaccination of mice
    Simone Korten
    Department of Immunology, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, 20359 Hamburg, Germany
    Infect Immun 73:849-58. 2005
    ..Furthermore, double-positive INF-gamma+/TNF-alpha+ CD8+ T cells were enriched in protected livers, suggesting that cells expressing both of these cytokines may be most relevant for protection...
  2. doi request reprint The nematode parasite Onchocerca volvulus generates the transforming growth factor-beta (TGF-beta)
    Simone Korten
    Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Str 74, 20359, Hamburg, Germany
    Parasitol Res 105:731-41. 2009
    ..Pleomorphic neoplasms in O. volvulus were also labeled. We conclude that latent TGF-beta protein is expressed by filariae independently of Wolbachia, possibly regulating worm tissue homeostasis...
  3. doi request reprint Natural death of adult Onchocerca volvulus and filaricidal effects of doxycycline induce local FOXP3+/CD4+ regulatory T cells and granzyme expression
    Simone Korten
    Department of Immunology, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Strasse 74, D 20359 Hamburg, Germany
    Microbes Infect 10:313-24. 2008
    ..We newly report granzyme responses to helminths and their association with immunosuppression. FOXP3+Treg and granzyme+ cells might locally suppress defence against newly acquired worms...
  4. pmc Immunohistology of ectopic secondary lymph follicles in subcutaneous nodules from patients with hyperreactive onchocerciasis (sowda)
    Norbert W Brattig
    Department of Molecular Medicine, Bernhard Nocht Institute for Tropical Medicine BNI, Bernhard Nocht Str 74, Hamburg, Germany
    Parasitol Res 107:657-66. 2010
    ..In conclusion, the ectopic secondary lymph follicles in onchocercomas and lymph nodes from hyperreactive onchocerciasis patients are equally composed...
  5. ncbi request reprint Expansion of NK cells with reduction of their inhibitory Ly-49A, Ly-49C, and Ly-49G2 receptor-expressing subsets in a murine helminth infection: contribution to parasite control
    Simone Korten
    Department of Medical Microbiology and Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
    J Immunol 168:5199-206. 2002
    ..These data demonstrate a new role for NK cells in the host defense against filariae and, for the first time, alterations of Ly-49 receptor-expressing NK cell subsets in a parasitic infection...
  6. doi request reprint A novel and divergent role of granzyme A and B in resistance to helminth infection
    Wiebke Hartmann
    Department of Immunology, Bernhard Nocht Institute for Tropical Medicine, D 20359 Hamburg, Germany
    J Immunol 186:2472-81. 2011
    ..This suggests a novel and divergent role for gzms in helminth infection, with gzmA contributing to resistance and gzmB promoting susceptibility...
  7. ncbi request reprint Enhanced CD8+ T cell immune responses and protection elicited against Plasmodium berghei malaria by prime boost immunization regimens using a novel attenuated fowlpox virus
    Richard J Anderson
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
    J Immunol 172:3094-100. 2004
    ..berghei and was more immunogenic and protective than DNA/MVA prime/boost immunization. However, further improvement was not achieved by sequential (triple) immunization with a DNA vaccine, FP9, and MVA...
  8. ncbi request reprint Modulation of Ly49 D expression after allogeneic bone marrow transplantation and functional consequences
    Esther Wilk
    Abteilung Klinische Immunologie, Medizinische Hochschule Hannover, Germany
    Immunobiology 205:267-81. 2002
    ..Functional data indicate that a time of reduced NK cell cytotoxicity after BMT is followed by in vitro tolerance of allogeneic chimeras...