H Benes

Summary

Country: Germany

Publications

  1. ncbi request reprint Transdermal lisuride: short-term efficacy and tolerability study in patients with severe restless legs syndrome
    Heike Benes
    Somni bene Institute for Medical Research and Sleep Medicine Schwerin Ltd, Arsenalstrasse 10, 19053 Schwerin, Germany
    Sleep Med 7:31-5. 2006
  2. doi request reprint Empirical evaluation of the accuracy of diagnostic criteria for Restless Legs Syndrome
    Heike Benes
    Somni Bene Institute for Medical Research and Sleep Medicine, Schwerin and Neurology Department, University of Rostock, Germany
    Sleep Med 10:524-30. 2009
  3. pmc Psychological distress of patients suffering from restless legs syndrome: a cross-sectional study
    Hanna Scholz
    Interdisciplinary Pain Centre, University Medical Centre, Freiburg 79106, Germany
    Health Qual Life Outcomes 9:73. 2011
  4. pmc Treatment of moderate to severe restless legs syndrome: 2-year safety and efficacy of rotigotine transdermal patch
    Birgit Hogl
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    BMC Neurol 10:86. 2010
  5. ncbi request reprint Lisuride treatment of restless legs syndrome: first studies with monotherapy in de novo patients and in combination with levodopa in advanced disease
    H Benes
    Somni Bene Institute for Medical Research and Sleep Medicine, Schwerin, Germany
    J Neural Transm 113:87-92. 2006
  6. doi request reprint Validation of an algorithm for the diagnosis of Restless Legs Syndrome: The Restless Legs Syndrome-Diagnostic Index (RLS-DI)
    Heike Benes
    Somni Bene Institute for Medical Research and Sleep Medicine Schwerin and Neurology Department, University of Rostock, Germany
    Sleep Med 10:515-23. 2009
  7. ncbi request reprint Definition of restless legs syndrome, how to diagnose it, and how to differentiate it from RLS mimics
    Heike Benes
    Somni Bene Institute for Medical Research and Sleep Medicine, Schwerin, Germany
    Mov Disord 22:S401-8. 2007
  8. ncbi request reprint Rapid onset of action of levodopa in restless legs syndrome: a double-blind, randomized, multicenter, crossover trial
    H Benes
    Neurology Clinic, Schwerin, Germany
    Sleep 22:1073-81. 1999
  9. doi request reprint Efficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trial
    Claudia Trenkwalder
    Paracelsus Elena Hospital, Kassel, Germany
    Lancet Neurol 7:595-604. 2008
  10. ncbi request reprint Cabergoline compared to levodopa in the treatment of patients with severe restless legs syndrome: results from a multi-center, randomized, active controlled trial
    Claudia Trenkwalder
    Paracelsus Elena Hospital, University of Gottingen, Kassel, Germany
    Mov Disord 22:696-703. 2007

Detail Information

Publications16

  1. ncbi request reprint Transdermal lisuride: short-term efficacy and tolerability study in patients with severe restless legs syndrome
    Heike Benes
    Somni bene Institute for Medical Research and Sleep Medicine Schwerin Ltd, Arsenalstrasse 10, 19053 Schwerin, Germany
    Sleep Med 7:31-5. 2006
    ....
  2. doi request reprint Empirical evaluation of the accuracy of diagnostic criteria for Restless Legs Syndrome
    Heike Benes
    Somni Bene Institute for Medical Research and Sleep Medicine, Schwerin and Neurology Department, University of Rostock, Germany
    Sleep Med 10:524-30. 2009
    ..In this article, we report a systematic empirical analysis of the accuracy of diagnostic decisions based on all diagnostic criteria being either "essential" or "non-essential."..
  3. pmc Psychological distress of patients suffering from restless legs syndrome: a cross-sectional study
    Hanna Scholz
    Interdisciplinary Pain Centre, University Medical Centre, Freiburg 79106, Germany
    Health Qual Life Outcomes 9:73. 2011
    ..Little is known about the psychological characteristics of RLS patients although psychological factors may contribute to unfavourable treatment outcome...
  4. pmc Treatment of moderate to severe restless legs syndrome: 2-year safety and efficacy of rotigotine transdermal patch
    Birgit Hogl
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    BMC Neurol 10:86. 2010
    ..This study reports the 2-year follow-up safety and efficacy data of an ongoing open-label multicenter extension study (NCT00498186) of transdermal rotigotine in patients with moderate to severe restless legs syndrome (RLS)...
  5. ncbi request reprint Lisuride treatment of restless legs syndrome: first studies with monotherapy in de novo patients and in combination with levodopa in advanced disease
    H Benes
    Somni Bene Institute for Medical Research and Sleep Medicine, Schwerin, Germany
    J Neural Transm 113:87-92. 2006
    ..Levodopa dose could be decreased by 27%. Lisuride might be an efficacious treatment for RLS in general, and in combination with levodopa in advanced stage...
  6. doi request reprint Validation of an algorithm for the diagnosis of Restless Legs Syndrome: The Restless Legs Syndrome-Diagnostic Index (RLS-DI)
    Heike Benes
    Somni Bene Institute for Medical Research and Sleep Medicine Schwerin and Neurology Department, University of Rostock, Germany
    Sleep Med 10:515-23. 2009
    ..We present the RLS-Diagnostic Index (RLS-DI), a diagnostic algorithm which combines essential and supportive diagnostic criteria from patient interviews, polysomnography and neurological examination in an adaptive procedure...
  7. ncbi request reprint Definition of restless legs syndrome, how to diagnose it, and how to differentiate it from RLS mimics
    Heike Benes
    Somni Bene Institute for Medical Research and Sleep Medicine, Schwerin, Germany
    Mov Disord 22:S401-8. 2007
    ..Standardized methods to assess a RLS diagnosis are presented which might improve differential diagnosis and in general the reliability and validity of RLS diagnosis...
  8. ncbi request reprint Rapid onset of action of levodopa in restless legs syndrome: a double-blind, randomized, multicenter, crossover trial
    H Benes
    Neurology Clinic, Schwerin, Germany
    Sleep 22:1073-81. 1999
    ..CONCLUSIONS: Levodopa/benserazide is effective and safe in the treatment of RLS. Objective and subjective measures of sleep improved rapidly after the first dose. RLS symptoms recurred immediately after treatment was discontinued...
  9. doi request reprint Efficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trial
    Claudia Trenkwalder
    Paracelsus Elena Hospital, Kassel, Germany
    Lancet Neurol 7:595-604. 2008
    ..Continuous administration of a dopamine agonist could be used to treat patients with restless legs syndrome. Our aim was to investigate the efficacy of transdermal rotigotine in the treatment of idiopathic restless legs syndrome...
  10. ncbi request reprint Cabergoline compared to levodopa in the treatment of patients with severe restless legs syndrome: results from a multi-center, randomized, active controlled trial
    Claudia Trenkwalder
    Paracelsus Elena Hospital, University of Gottingen, Kassel, Germany
    Mov Disord 22:696-703. 2007
    ..0001). This first large-scale active controlled study in RLS showed superior efficacy of cabergoline versus levodopa after a 30-week long-term therapy. Tolerability was found more favorable with levodopa than with cabergoline...
  11. ncbi request reprint Efficacy of rotigotine transdermal system in severe restless legs syndrome: a randomized, double-blind, placebo-controlled, six-week dose-finding trial in Europe
    Wolfgang H Oertel
    Department of Neurology, Philipps University, Rudolf Bultmann Strasse 8, D 35039 Marburg, Germany
    Sleep Med 9:228-39. 2008
    ..In a pilot placebo-controlled study, low dosages of 0.5-2mg/24h rotigotine showed a dose-dependent beneficial effect in restless legs syndrome (RLS) patients...
  12. ncbi request reprint Assessment of restless legs syndrome--methodological approaches for use in practice and clinical trials
    Ralf Kohnen
    IMEREM Institute for Medical Research Management, Biometrics Ltd, University of Erlangen Nuremberg, Nuremberg, Germany
    Mov Disord 22:S485-94. 2007
    ....
  13. ncbi request reprint Clinical trials in restless legs syndrome--recommendations of the European RLS Study Group (EURLSSG)
    Claudia Trenkwalder
    Paracelsus Elena Hospital, Center of Parkinsonism and Movement Disorders, Klinikstr 16, 34128 Kassel, Germany
    Mov Disord 22:S495-504. 2007
    ..The aim of these recommendations is to support research groups or pharmaceutical companies in the design of optimized study protocols...
  14. ncbi request reprint Augmentation as a treatment complication of restless legs syndrome: concept and management
    Diego Garcia-Borreguero
    Sleep Research Institute, Alberto Alcocer 19, 28036 Madrid, Spain
    Mov Disord 22:S476-84. 2007
    ..The present article reviews our current knowledge on clinical diagnosis, evaluation, pathophysiology, and treatment recommendations for this condition...
  15. ncbi request reprint State of the art in restless legs syndrome therapy: practice recommendations for treating restless legs syndrome
    Wolfgang H Oertel
    Department of Neurology, Philipps University, Marburg, Germany
    Mov Disord 22:S466-75. 2007
    ..Opioids and anticonvulsants such as gabapentine are second-line options in individual patients. Iron substitution is justified in people with iron deficiency related RLS (ferritin concentration lower than 50 microg/L)...
  16. ncbi request reprint Long-term safety and efficacy of cabergoline for the treatment of idiopathic restless legs syndrome: results from an open-label 6-month clinical trial
    Heike Benes
    HELIOS Kliniken, Clinic of Neurology, Sleep Laboratory, Schwerin, Germany
    Sleep 27:674-82. 2004
    ..To assess the safety and efficacy of cabergoline in the treatment of idiopathic restless legs syndrome (RLS) patients...