R Bender

Summary

Country: Germany

Publications

  1. ncbi request reprint Generating survival times to simulate Cox proportional hazards models
    Ralf Bender
    Institute for Quality and Efficiency in Health Care, Cologne, Germany
    Stat Med 24:1713-23. 2005
  2. pmc A note on the graphical presentation of prediction intervals in random-effects meta-analyses
    Charlotte Guddat
    Department of Medical Biometry, Institute for Quality and Efficiency in Health Care IQWiG, Im Mediapark 8, Cologne, 50670, Germany
    Syst Rev 1:34. 2012
  3. pmc Reporting of loss to follow-up information in randomised controlled trials with time-to-event outcomes: a literature survey
    Elke Vervölgyi
    Institute for Quality and Efficiency in Health Care IQWiG, Dillenburger Str 27, 51105 Cologne, Germany
    BMC Med Res Methodol 11:130. 2011
  4. pmc Calculation of NNTs in RCTs with time-to-event outcomes: a literature review
    Mandy Hildebrandt
    Institute for Quality and Efficiency in Health Care IQWiG, Cologne, Germany
    BMC Med Res Methodol 9:21. 2009
  5. pmc Calculating confidence intervals for impact numbers
    Mandy Hildebrandt
    Department of Medical Biometry, Institute for Quality and Efficiency in Health Care IQWiG, Dillenburger Str, 27, 51105 Cologne, Germany
    BMC Med Res Methodol 6:32. 2006
  6. pmc Predicting the risk of falling--efficacy of a risk assessment tool compared to nurses' judgement: a cluster-randomised controlled trial [ISRCTN37794278]
    Gabriele Meyer
    Unit of Health Sciences and Education, University of Hamburg, Martin Luther King Platz 6, D 20146 Hamburg, Germany
    BMC Geriatr 5:14. 2005
  7. ncbi request reprint Causes of death in obesity: relevant increase in cardiovascular but not in all-cancer mortality
    Ralf Bender
    Institute for Quality and Efficiency in Health Care, Dillenburger Str 27, Cologne D 51105, Germany
    J Clin Epidemiol 59:1064-71. 2006
  8. ncbi request reprint [Analysis of variance for repeated measurements]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e61-4. 2007
  9. ncbi request reprint [Analysis of variance]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e57-60. 2007
  10. ncbi request reprint [Common significance tests]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e24-5. 2007

Detail Information

Publications48

  1. ncbi request reprint Generating survival times to simulate Cox proportional hazards models
    Ralf Bender
    Institute for Quality and Efficiency in Health Care, Cologne, Germany
    Stat Med 24:1713-23. 2005
    ....
  2. pmc A note on the graphical presentation of prediction intervals in random-effects meta-analyses
    Charlotte Guddat
    Department of Medical Biometry, Institute for Quality and Efficiency in Health Care IQWiG, Im Mediapark 8, Cologne, 50670, Germany
    Syst Rev 1:34. 2012
    ..This means that in forest plots of RE meta-analyses, no estimate of the between-study variation is usually given graphically, even though it provides important information about the heterogeneity between the study effect sizes...
  3. pmc Reporting of loss to follow-up information in randomised controlled trials with time-to-event outcomes: a literature survey
    Elke Vervölgyi
    Institute for Quality and Efficiency in Health Care IQWiG, Dillenburger Str 27, 51105 Cologne, Germany
    BMC Med Res Methodol 11:130. 2011
    ..To assess the reporting of loss to follow-up (LTFU) information in articles on randomised controlled trials (RCTs) with time-to-event outcomes, and to assess whether discrepancies affect the validity of study results...
  4. pmc Calculation of NNTs in RCTs with time-to-event outcomes: a literature review
    Mandy Hildebrandt
    Institute for Quality and Efficiency in Health Care IQWiG, Cologne, Germany
    BMC Med Res Methodol 9:21. 2009
    ..The frequency of using NNTs to report results of randomised controlled trials (RCT) investigating time-to-event outcomes and the adequacy of the applied calculation methods are unknown...
  5. pmc Calculating confidence intervals for impact numbers
    Mandy Hildebrandt
    Department of Medical Biometry, Institute for Quality and Efficiency in Health Care IQWiG, Dillenburger Str, 27, 51105 Cologne, Germany
    BMC Med Res Methodol 6:32. 2006
    ..In this paper, we present methods to calculate confidence intervals for the new impact numbers in the situation of cohort studies...
  6. pmc Predicting the risk of falling--efficacy of a risk assessment tool compared to nurses' judgement: a cluster-randomised controlled trial [ISRCTN37794278]
    Gabriele Meyer
    Unit of Health Sciences and Education, University of Hamburg, Martin Luther King Platz 6, D 20146 Hamburg, Germany
    BMC Geriatr 5:14. 2005
    ..The present study will evaluate the clinical efficacy and consequences of different fall risk assessment strategies...
  7. ncbi request reprint Causes of death in obesity: relevant increase in cardiovascular but not in all-cancer mortality
    Ralf Bender
    Institute for Quality and Efficiency in Health Care, Dillenburger Str 27, Cologne D 51105, Germany
    J Clin Epidemiol 59:1064-71. 2006
    ..To assess the relation between body mass index (BMI) and the risk of death from various causes in a prospective cohort study...
  8. ncbi request reprint [Analysis of variance for repeated measurements]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e61-4. 2007
  9. ncbi request reprint [Analysis of variance]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e57-60. 2007
  10. ncbi request reprint [Common significance tests]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e24-5. 2007
  11. ncbi request reprint [What is a confidence interval?]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e17-8. 2007
  12. ncbi request reprint [Multiple testing]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e26-9. 2007
  13. ncbi request reprint [Logistic regression]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e33-5. 2007
  14. ncbi request reprint [Serial data curves]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e22-3. 2007
  15. ncbi request reprint [What is the p-value?]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e15-6. 2007
  16. ncbi request reprint [The 2 by 2 table]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e12-4. 2007
  17. ncbi request reprint [Possibilities and limitations of statistical regression models for the calculation of threshold values for minimum provider volumes]
    Ralf Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln
    Z Arztl Fortbild Qualitatssich 100:93-8. 2006
    ..In order to verify that a minimum provider volume leads to the expected quality improvement, a prospective intervention study is required...
  18. doi request reprint Estimating adjusted NNTs in randomised controlled trials with binary outcomes: a simulation study
    Ralf Bender
    Department of Medical Biometry, Institute for Quality and Efficiency in Health Care IQWiG, D 51105 Cologne, Germany
    Contemp Clin Trials 31:498-505. 2010
    ..Therefore, it is preferable to adjust for balanced covariates in RCTs when the treatment effect is expressed in terms of risk differences and NNTs and the covariate represents a strong predictor...
  19. doi request reprint Attention should be given to multiplicity issues in systematic reviews
    Ralf Bender
    Institute for Quality and Efficiency in Health Care, Dillenburger Street 27, Cologne, Germany
    J Clin Epidemiol 61:857-65. 2008
    ..The objective of this paper is to describe the problem of multiple comparisons in systematic reviews and to provide some guidelines on how to deal with it in practice...
  20. ncbi request reprint Estimating adjusted NNT measures in logistic regression analysis
    Ralf Bender
    Department of Medical Biometry, Institute for Quality and Efficiency in Health Care IQWiG, Cologne, Germany
    Stat Med 26:5586-95. 2007
    ..The proposed method is illustrated by application to data of a cohort study investigating the effect of smoking on coronary heart disease...
  21. ncbi request reprint Tutorial: using confidence curves in medical research
    Ralf Bender
    Institute for Quality and Efficiency in Health Care, Cologne, Germany
    Biom J 47:237-47. 2005
    ..In medical research more emphasis on the choice between the one- and two-sided approaches should be given. One- and two-sided confidence curves are useful complements to the conventional methods of presenting study results...
  22. ncbi request reprint [Multiple regression]
    R Bender
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e30-2. 2007
  23. pmc Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study
    L G Hemkens
    Institute for Quality and Efficiency in Health Care IQWiG, Dillenburger Strasse 27, D 51105, Cologne, Germany
    Diabetologia 52:1732-44. 2009
    ..The aim of this cohort study was to investigate the risk of malignant neoplasms and mortality in patients with diabetes treated either with human insulin or with one of three insulin analogues...
  24. ncbi request reprint [The kappa coefficient]
    U Grouven
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e65-8. 2007
  25. ncbi request reprint [Linear regression and correlation]
    S Lange
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e9-11. 2007
  26. ncbi request reprint [Measures of variability]
    S Lange
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e5-6. 2007
  27. ncbi request reprint [Comparing methods of measurement]
    U Grouven
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e69-73. 2007
  28. ncbi request reprint [Quantiles, cumulative distribution function, and box-plot]
    S Lange
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e3-4. 2007
  29. ncbi request reprint [Equivalence and non-inferiority trials]
    S Lange
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e53-6. 2007
  30. doi request reprint Introduction to the use of regression models in epidemiology
    Ralf Bender
    Institute for Quality and Efficiency in Health Care, Cologne, Germany
    Methods Mol Biol 471:179-95. 2009
    ..This chapter provides a nontechnical introduction to these regression models with illustrating examples from cancer research...
  31. doi request reprint Flexible regression models are useful tools to calculate and assess threshold values in the context of minimum provider volumes
    Ulrich Grouven
    Institute for Quality and Efficiency in Health Care, Cologne, Germany
    J Clin Epidemiol 61:1125-31. 2008
    ..The aim was to review different approaches for the derivation of threshold values and to discuss their strengths and limitations in the context of minimum provider volumes...
  32. ncbi request reprint [Assessment of the number of cardio- and cerebrovascular events due to rofecoxib (Vioxx) in Germany between 2001 and 2004]
    Peter T Sawicki
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen IQWiG, Koln
    Med Klin (Munich) 101:191-7. 2006
    ....
  33. ncbi request reprint [The histogram]
    S Lange
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e7-8. 2007
  34. ncbi request reprint [What is a significance test? General issues]
    S Lange
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e19-21. 2007
  35. ncbi request reprint [Median or mean?]
    S Lange
    Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, Koln, Germany
    Dtsch Med Wochenschr 132:e1-2. 2007
  36. doi request reprint Intervention effects in the case of heterogeneity between three subgroups. Assessment within the framework of systematic reviews
    G Skipka
    Institute for Quality and Efficiency in Health Care, IQWiG, Dillenburger Str 27, 51105 Köln, Germany
    Methods Inf Med 49:613-7. 2010
    ..In this case, the problem of non-transitive relations may occur if the significance level is fixed at 0.05 for all tests...
  37. doi request reprint Logistic regression was preferred to estimate risk differences and numbers needed to be exposed adjusted for covariates
    Ulrich Gehrmann
    Department of Medical Biometry, Institute for Quality and Efficiency in Health Care IQWiG, Dillenburger Street 27, Cologne, Germany
    J Clin Epidemiol 63:1223-31. 2010
    ..A novel proposal is given by logistic regression with average risk difference (LR-ARD) estimation. Finally, the use of ordinary linear regression and unadjusted estimation can be considered...
  38. ncbi request reprint Generating survival times to simulate Cox proportional hazards models by Ralf Bender, Thomas Augustin and Maria Blettner, Statistics in Medicine 2005; 24:1713-1723
    Ralf Bender
    Stat Med 25:1978-9. 2006
  39. ncbi request reprint Calculating the "number needed to be exposed" with adjustment for confounding variables in epidemiological studies
    Ralf Bender
    Department of Epidemiology and Medical Statistics, School of Public Health, University of Bielefeld, PO Box 100131, D 33501 Bielefeld, Germany
    J Clin Epidemiol 55:525-30. 2002
    ..The adjusted number needed to be exposed can be a useful complement to the commonly presented results in epidemiological studies, such as ORs and attributable risks...
  40. ncbi request reprint Effect of Berkson measurement error on parameter estimates in Cox regression models
    Helmut Kuchenhoff
    Department of Statistics, Ludwig Maximilians Universitat, Akademiestr 1, 80799, Munchen, Germany
    Lifetime Data Anal 13:261-72. 2007
    ..Even the effect of a Berkson measurement error with high variance, which is not unrealistic in our example, is a negligible attenuation of the observed effect. However, this effect is more pronounced for multiplicative measurement error...
  41. ncbi request reprint Body weight, blood pressure, and mortality in a cohort of obese patients
    Ralf Bender
    Department of Epidemiology and Medical Statistics, School of Public Health, University of Bielefeld, Bielefeld, Germany
    Am J Epidemiol 156:239-45. 2002
    ..0, 2.7) but not for women (hazard ratio = 0.71, 95% confidence interval: 0.4, 1.2). These findings support previous observations that the risk of death is lower for hypertensive men in high compared with low BMI groups...
  42. ncbi request reprint The impact of non-compliance with the therapeutic regimen on the development of stroke among hypertensive men and women in Gaza, Palestine
    Bernhard T Baune
    Department of Psychiatry and Psychotherapy, University of Muenster, Albert Schweitzer Street 11, D 48129 Muenster, Germany
    Saudi Med J 25:1683-8. 2004
    ..To identify potential risk factors we investigated compliance with the therapeutic regimen and life style factors which may increase the risk for stroke...
  43. ncbi request reprint A new classification plot for the C-peptide suppression test
    Christiane Saddig
    Department of Metabolic Diseases and Nutrition, Heinrich Heine University of Duesseldorf, Duesseldorf, Germany
    JOP 3:16-25. 2002
    ..To evaluate the C-peptide suppression test as a screening test in patients with symptoms of hypoglycemia as compared to the standard fasting test...
  44. ncbi request reprint Confidence intervals for adjusted NNEs: a simulation study
    Ralf Bender
    J Clin Epidemiol 56:205-6. 2003
  45. ncbi request reprint Predictors of adherence to the use of hip protectors in nursing home residents
    Andrea Warnke
    Unit of Health Sciences and Education, University of Hamburg, Hamburg, Germany
    J Am Geriatr Soc 52:340-5. 2004
    ..To assess predictors of hip-protector use in nursing home residents under usual-care conditions and after intervention consisting of structured education of nurses and nursing home residents and provision of free hip protectors...
  46. ncbi request reprint Eight-year trends in food, energy and macronutrient intake in a sample of elderly German subjects
    Svenja M Jungjohann
    Institute of Nutritional Science, Justus Liebig University, Goethestr 55, D 35 390 Giessen, Germany
    Br J Nutr 93:361-78. 2005
    ..79 and -2.56 g/d per year). The healthier food choices and the ability to change food habits could be related to the relatively high health-awareness of the GISELA subjects compared to the federal average of equivalent age groups...
  47. ncbi request reprint Flexible intensive insulin therapy in adults with type 1 diabetes and high risk for severe hypoglycemia and diabetic ketoacidosis
    Alexander Sämann
    Department of Internal Medicine III, Friedrich Schiller University, 07740 Jena, Germany
    Diabetes Care 29:2196-9. 2006
    ..This study evaluates DTTP outcomes in patients at high risk for severe hypoglycemia and severe ketoacidosis...
  48. ncbi request reprint Breastfeeding promotion in non-UNICEF-certified hospitals and long-term breastfeeding success in Germany
    M Dulon
    Department of Epidemiology and Medical Statistics, School of Public Health, University of Bielefeld, Germany
    Acta Paediatr 92:653-8. 2003
    ....