Genomes and Genes
H G Beisel
- Tachylectin-2: crystal structure of a specific GlcNAc/GalNAc-binding lectin involved in the innate immunity host defense of the Japanese horseshoe crab Tachypleus tridentatusH G Beisel
Max Planck Institut fur Biochemie, Am Klopferspitz 18a, 82152 Martinsried, Germany
EMBO J 18:2313-22. 1999..Thus, tachylectin-2 employs strict specificity for certain N-acetyl sugars as well as the surface ligand density for self/non-self recognition...
- The 2.0-A crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systemsN Kairies
Max Planck Institut fur Biochemie, Abteilung Strukturforschung, Am Klopferspitz 18a, 82152 Martinsried, Germany
Proc Natl Acad Sci U S A 98:13519-24. 2001..Our observations provide the first structural evidence of a common ancestor for the innate immunity and the blood coagulation systems...
- Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like foldA Eichinger
Max Planck Institut fur Biochemie, Abteilung Strukturforschung, D 82152 Martinsried, Germany
EMBO J 18:5453-62. 1999..Here we show the binding mode of an arginine-containing inhibitor in the active-site, thus identifying major interaction sites defining a suitable pharmacophor...