H G Beisel

Summary

Country: Germany

Publications

  1. pmc Tachylectin-2: crystal structure of a specific GlcNAc/GalNAc-binding lectin involved in the innate immunity host defense of the Japanese horseshoe crab Tachypleus tridentatus
    H G Beisel
    Max Planck Institut fur Biochemie, Am Klopferspitz 18a, 82152 Martinsried, Germany
    EMBO J 18:2313-22. 1999
  2. pmc The 2.0-A crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems
    N Kairies
    Max Planck Institut fur Biochemie, Abteilung Strukturforschung, Am Klopferspitz 18a, 82152 Martinsried, Germany
    Proc Natl Acad Sci U S A 98:13519-24. 2001
  3. pmc Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold
    A Eichinger
    Max Planck Institut fur Biochemie, Abteilung Strukturforschung, D 82152 Martinsried, Germany
    EMBO J 18:5453-62. 1999

Collaborators

Detail Information

Publications3

  1. pmc Tachylectin-2: crystal structure of a specific GlcNAc/GalNAc-binding lectin involved in the innate immunity host defense of the Japanese horseshoe crab Tachypleus tridentatus
    H G Beisel
    Max Planck Institut fur Biochemie, Am Klopferspitz 18a, 82152 Martinsried, Germany
    EMBO J 18:2313-22. 1999
    ..Thus, tachylectin-2 employs strict specificity for certain N-acetyl sugars as well as the surface ligand density for self/non-self recognition...
  2. pmc The 2.0-A crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems
    N Kairies
    Max Planck Institut fur Biochemie, Abteilung Strukturforschung, Am Klopferspitz 18a, 82152 Martinsried, Germany
    Proc Natl Acad Sci U S A 98:13519-24. 2001
    ..Our observations provide the first structural evidence of a common ancestor for the innate immunity and the blood coagulation systems...
  3. pmc Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold
    A Eichinger
    Max Planck Institut fur Biochemie, Abteilung Strukturforschung, D 82152 Martinsried, Germany
    EMBO J 18:5453-62. 1999
    ..Here we show the binding mode of an arginine-containing inhibitor in the active-site, thus identifying major interaction sites defining a suitable pharmacophor...