H Beckmann

Summary

Country: Germany

Publications

  1. ncbi request reprint The human striatum in schizophrenia. II. Increased number of striatal neurons in schizophrenics
    H Beckmann
    Department of Psychiatry, University of Wurzburg, Germany
    Psychiatry Res 68:99-109. 1997
  2. ncbi request reprint Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder
    J Deckert
    Department of Psychiatry, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany, Istituto di Ricovero e Cura a Carattere Scientifico H San Raffaele, DSNP, Via Prinetti 29, 20127 Milan, Italy
    Hum Mol Genet 8:621-4. 1999
  3. ncbi request reprint Absence of a subgroup of chronic schizophrenia in monozygotic twins. Consequences for considerations on the pathogenesis of schizophrenic psychoses
    B Pfuhlmann
    ,
    Eur Arch Psychiatry Clin Neurosci 249:50-4. 1999
  4. ncbi request reprint Echogenicity of substantia nigra determined by transcranial ultrasound correlates with severity of parkinsonian symptoms induced by neuroleptic therapy
    D Berg
    Department of Neurology, , , Germany
    Biol Psychiatry 50:463-7. 2001
  5. ncbi request reprint Norepinephrine transporter gene (NET) variants in patients with panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Füchsleinstrazze 15, D 97080, Wurzburg, Germany
    Neurosci Lett 333:41-4. 2002
  6. ncbi request reprint The genetic heterogeneity of "schizophrenia"
    H Beckmann
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15 97080 Wurzburg, Germany
    World J Biol Psychiatry 1:35-41. 2000
  7. ncbi request reprint Multidimensional analysis of the concentrations of 17 substances in the CSF of schizophrenics and controls
    H Beckmann
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Federal Republic of Germany
    J Neural Transm 109:931-8. 2002
  8. ncbi request reprint Developmental malformations in cerebral structures in "endogenous psychoses"
    H Beckmann
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Federal Republic of Germany
    J Neural Transm 109:421-31. 2002
  9. ncbi request reprint Developmental malformations in cerebral structures of schizophrenic patients
    H Beckmann
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Germany
    Eur Arch Psychiatry Clin Neurosci 249:44-7. 1999
  10. pmc Splitting schizophrenia: periodic catatonia-susceptibility locus on chromosome 15q15
    G Stober
    1Department of Psychiatry and Psychotherapy, University of Wurzburg, 97080 Wurzburg, Germany
    Am J Hum Genet 67:1201-7. 2000

Detail Information

Publications38

  1. ncbi request reprint The human striatum in schizophrenia. II. Increased number of striatal neurons in schizophrenics
    H Beckmann
    Department of Psychiatry, University of Wurzburg, Germany
    Psychiatry Res 68:99-109. 1997
    ..Cortical development disturbances with a consecutive reduction of naturally occurring cell death during development could be responsible for this increase in absolute striatal neuron numbers in schizophrenics...
  2. ncbi request reprint Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder
    J Deckert
    Department of Psychiatry, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany, Istituto di Ricovero e Cura a Carattere Scientifico H San Raffaele, DSNP, Via Prinetti 29, 20127 Milan, Italy
    Hum Mol Genet 8:621-4. 1999
    ....
  3. ncbi request reprint Absence of a subgroup of chronic schizophrenia in monozygotic twins. Consequences for considerations on the pathogenesis of schizophrenic psychoses
    B Pfuhlmann
    ,
    Eur Arch Psychiatry Clin Neurosci 249:50-4. 1999
    ..e., a lack of communication during childhood, may result in distinct biological damage to functional brain systems and, thus, may play a role in the pathogenesis of these psychoses...
  4. ncbi request reprint Echogenicity of substantia nigra determined by transcranial ultrasound correlates with severity of parkinsonian symptoms induced by neuroleptic therapy
    D Berg
    Department of Neurology, , , Germany
    Biol Psychiatry 50:463-7. 2001
    ..01). CONCLUSIONS: Increased echogenicity of the substantia nigra is associated with impaired function of the nigrostriatal system that can be disclosed by neuroleptic drugs...
  5. ncbi request reprint Norepinephrine transporter gene (NET) variants in patients with panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Füchsleinstrazze 15, D 97080, Wurzburg, Germany
    Neurosci Lett 333:41-4. 2002
    ..Except for a silent substitution (G1287A), overall frequencies of variant alleles were low (< or =0.016). None of the variants under study was found to be associated with PD regardless of an additional diagnosis of agoraphobia...
  6. ncbi request reprint The genetic heterogeneity of "schizophrenia"
    H Beckmann
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15 97080 Wurzburg, Germany
    World J Biol Psychiatry 1:35-41. 2000
    ..Unsystematic schizophrenias, however, are predominantly inherited and "environmental" factors are not very prominent...
  7. ncbi request reprint Multidimensional analysis of the concentrations of 17 substances in the CSF of schizophrenics and controls
    H Beckmann
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Federal Republic of Germany
    J Neural Transm 109:931-8. 2002
    ....
  8. ncbi request reprint Developmental malformations in cerebral structures in "endogenous psychoses"
    H Beckmann
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Federal Republic of Germany
    J Neural Transm 109:421-31. 2002
    ....
  9. ncbi request reprint Developmental malformations in cerebral structures of schizophrenic patients
    H Beckmann
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Germany
    Eur Arch Psychiatry Clin Neurosci 249:44-7. 1999
    ..Nevertheless, the interaction between a genetic predisposition and exogenous noxious agents in such cases still needs to be clarified in our understanding of the etiology of schizophrenic psychoses...
  10. pmc Splitting schizophrenia: periodic catatonia-susceptibility locus on chromosome 15q15
    G Stober
    1Department of Psychiatry and Psychotherapy, University of Wurzburg, 97080 Wurzburg, Germany
    Am J Hum Genet 67:1201-7. 2000
    ..Our findings provide evidence that periodic catatonia is associated with a major disease locus, which maps to chromosome 15q15...
  11. ncbi request reprint Linkage and family-based association study of schizophrenia and the synapsin III locus that maps to chromosome 22q13
    G Stober
    Department of Psychiatry, University of Wurzburg, Federal Republic of Germany
    Am J Med Genet 96:392-7. 2000
    ..In addition, no evidence for gender differences or parent-of-origin effects were found. Thus, the synapsin III locus at chromosome 22q13 is not likely to contain a schizophrenia susceptibility gene...
  12. ncbi request reprint Gender differences and age of onset in the catatonic subtypes of schizophrenia
    G Stober
    Department of Psychiatry, University of Wurzburg, Germany
    Psychopathology 31:307-12. 1998
    ..8% in late-onset probands. Our findings substantiate the hypothesis that periodic catatonia is a clinically homogenous disorder with a major gene effect and an age at onset which is to a large extent genetically determined...
  13. ncbi request reprint [Cycloid psychoses as atypical manic-depressive disorders. Results of a family study]
    B Jabs
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitat Wurzburg, Fuchsleinstrasse 15, 97080, Wurzburg, Germany
    Nervenarzt 77:1096-100, 1102-4. 2006
    ..Whereas a growing body of evidence suggests that cycloid psychoses have to be separated from schizophrenic psychoses, their relations to bipolar affective disorder are less clear...
  14. ncbi request reprint hKCNN3 which maps to chromosome 1q21 is not the causative gene in periodic catatonia, a familial subtype of schizophrenia
    G Stober
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Germany
    Eur Arch Psychiatry Clin Neurosci 250:163-8. 2000
    ..Linkage mapping showed segregation with marker D1S498 (theta = 0.05) and placed hKCNN3 in the genetic linkage map in a cluster of genes near the centromeric region of chromosome 1...
  15. ncbi request reprint Parent-of-origin effect and evidence for differential transmission in periodic catatonia
    G Stober
    Department of Psychiatry, University of Wurzburg, Germany
    Psychiatr Genet 8:213-9. 1998
    ..021). We therefore propose that parent-of-origin effects as well as prenatal mortality and psychosocial factors need further investigation in the periodic catatonia subtype of schizophrenia...
  16. ncbi request reprint Cycloid psychoses are not part of a bipolar affective spectrum: results of a controlled family study
    B Pfuhlmann
    Department of Psychiatry and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, D 97080 Wuerzburg, Germany
    J Affect Disord 83:11-9. 2004
    ..To further clarify this issue a controlled family study was undertaken...
  17. ncbi request reprint Functional PAX-6 gene-linked polymorphic region: potential association with paranoid schizophrenia
    G Stober
    Department of Psychiatry, University of Wurzburg, Germany
    Biol Psychiatry 45:1585-91. 1999
    ....
  18. ncbi request reprint Distribution of the B33 CTG repeat polymorphism in a subtype of schizophrenia
    D Bengel
    Department of Psychiatry, , Germany
    Eur Arch Psychiatry Clin Neurosci 248:78-81. 1998
    ..Nevertheless, that periodic catatonia displays dominant inheritance and anticipation, characteristic of genetic disorders involving trinucleotide repeats, justifies further screening for triplet repeat expansions in this illness...
  19. ncbi request reprint Disturbances of corticogenesis in schizophrenia: morphological findings provide new evidence for the maldevelopmental hypothesis
    P Kalus
    Neurobiological Research Laboratory, Department of Psychiatry, University of Wurzburg, Germany
    Neuropsychobiology 40:1-13. 1999
    ....
  20. ncbi request reprint Polymorphic MAO-A and 5-HT-transporter genes: analysis of interactions in panic disorder
    P Sand
    Department of Psychiatry, University of Wurzburg, Fuchsleinstr 15, 97080 Wurzburg, Germany
    World J Biol Psychiatry 1:147-50. 2000
    ..There was no significant difference in odds ratios, suggesting that the observed increase of genetic liability by the long MAO-A gene promoter allele is not modified by the 5-HTT gene promoter polymorphism...
  21. ncbi request reprint Exonic variants of the GABA(B) receptor gene and panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Germany
    Psychiatr Genet 10:191-4. 2000
    ..There was no indication of an increased vulnerability to panic disorder or agoraphobia with respect to the allelic variants under study...
  22. ncbi request reprint [Hypochondriacal euphoria as a special form of monopolar affective psychosis]
    B E Jabs
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitat Wurzburg
    Psychiatr Prax 28:29-34. 2001
    ..Based upon subtle observation of signs and course over many years, Karl Leonhard developed a concept of affective psychoses that permits a distinction of monopolar from bipolar forms, e.g. monopolar manias and euphoric euphorias...
  23. ncbi request reprint Disturbed neural circuits in a subtype of chronic catatonic schizophrenia demonstrated by F-18-FDG-PET and F-18-DOPA-PET
    M Lauer
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Federal Republic of Germany
    J Neural Transm 108:661-70. 2001
    ....
  24. ncbi request reprint Brain quinolinic acid in Alzheimer's dementia
    E Sofic
    Department of Psychiatry, University of Wurzburg, Federal Republic of Germany
    Eur Arch Psychiatry Neurol Sci 239:177-9. 1989
    ..The data do not support the hypothesis that an accumulation of QA plays a role in neuronal degeneration occurring in the frontal and temporal cortex, putamen and cerebellum of patients with SDAT...
  25. ncbi request reprint Granule cells of the dentate gyrus with basal and recurrent dendrites in schizophrenic patients and controls. A comparative Golgi study
    D Senitz
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Federal Republic of Germany
    J Neural Transm 110:317-26. 2003
    ..Whereas drug influences during lifetime cannot fully be excluded, we tend to interpret this finding as a plastic reaction to prenatal developmental malformations of the impinging rostral entorhinal region...
  26. ncbi request reprint Systematic mutation screening and association study of the A1 and A2a adenosine receptor genes in panic disorder suggest a contribution of the A2a gene to the development of disease
    J Deckert
    Department of Psychiatry, University of Wurzburg, Germany
    Mol Psychiatry 3:81-5. 1998
    ..Replication studies in independent samples with nuclear families applying the transmission disequilibrium test (TDT) are warranted...
  27. ncbi request reprint Exposure to prenatal infections, genetics and the risk of systematic and periodic catatonia
    G Stober
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Federal Republic of Germany
    J Neural Transm 109:921-9. 2002
    ..These findings support the hypothesis that distinct schizophrenia phenotypes are based on different etiological mechanisms...
  28. ncbi request reprint Increased volume of the nucleus accumbens in schizophrenia
    M Lauer
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Federal Republic of Germany
    J Neural Transm 108:645-60. 2001
    ..Most likely, this increase in volume of the ventral striatum reflects a decrease in naturally occuring cell death following prenatal cortical neurodevelopmental disturbances...
  29. ncbi request reprint Naturally occurring benzodiazepines: current status of research and clinical implications
    P Sand
    Department of Psychiatry, University of Wurzburg, Germany
    Eur Arch Psychiatry Clin Neurosci 250:194-202. 2000
    ..g., by gas chromatography/selected ion monitoring-mass spectrometry (GC/SIM-MS). This review summarizes existing evidence of benzodiazepines' occurrence in nature and discusses implications for neuropsychiatric disorders...
  30. ncbi request reprint In vivo and in vitro effects of glucocorticoids on lymphocyte proliferation in depression
    R Rupprecht
    Department of Psychiatry, , Federal Republic of Germany
    Eur Arch Psychiatry Clin Neurosci 241:35-40. 1991
    ..These data support the concept of a decreased functional plasticity of the glucocorticoid receptor in depression also at the cellular level...
  31. ncbi request reprint Systematic search for variation in the human norepinephrine transporter gene: identification of five naturally occurring missense mutations and study of association with major psychiatric disorders
    G Stober
    Institute of Human Genetics, University of Bonn, Germany
    Am J Med Genet 67:523-32. 1996
    ..The detection of a highly polymorphic silent 1287G/A polymorphism was utilized to demonstrate biallelic expression of the NET in adult human brain...
  32. ncbi request reprint (r)-, but not (s)-alpha lipoic acid stimulates deficient brain pyruvate dehydrogenase complex in vascular dementia, but not in Alzheimer dementia
    L Frolich
    Division of Geriatric Psychiatry, Central Institute of Mental Health Mannheim, University of Heidelberg, Germany
    J Neural Transm 111:295-310. 2004
    ....
  33. ncbi request reprint HAT3.1, a novel Arabidopsis homeodomain protein containing a conserved cysteine-rich region
    U Schindler
    University of Pennsylvania, Department of Biology, Philadelphia 19104 6018
    Plant J 4:137-50. 1993
    ..HAT3.1 mRNA was primarily detected in root tissue, implying a regulatory function of this protein in root development...
  34. ncbi request reprint Periodic catatonia: a schizophrenic subtype with major gene effect and anticipation
    G Stober
    Department of Psychiatry, University of Wuerzburg, Germany
    Eur Arch Psychiatry Clin Neurosci 245:135-41. 1995
    ..Thus, periodic catatonia as a specific clinical subtype of schizophrenia is a promising candidate for molecular genetic evaluation...
  35. ncbi request reprint ["Accentuated disposition"--rediscovery of an important concept in personality psychology]
    B Jabs
    Nervenarzt 73:690. 2002
  36. ncbi request reprint Risk assessment in patients with ruptured abdominal aortic aneurysms
    H W Kniemeyer
    Clinic for Vascular Surgery and Phlebology, Elisabeth Krankenhaus Essen, Germany
    Acta Chir Belg 102:176-82. 2002
    ..In a retrospective study attempts are made to identify individual organ-dysfunction risk profiles influencing the outcome...
  37. ncbi request reprint TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif
    H Beckmann
    Howard Hughes Medical Institute, University of Pennsylvania School of Medicine, Philadelphia 19104 6072
    Genes Dev 4:167-79. 1990
    ..Like the other muE3-binding proteins detected in nuclear extracts, in vitro-synthesized TFE3 also binds to the USF/MLTF site found in the adenovirus major late promoter...
  38. pmc Heterodimerization between light-regulated and ubiquitously expressed Arabidopsis GBF bZIP proteins
    U Schindler
    University of Pennsylvania, Department of Biology, Philadelphia 19104 6018
    EMBO J 11:1261-73. 1992
    ..Furthermore, we demonstrate that GBF1, GBF2 and GBF3 heterodimerize and these heterodimers also interact with the G-box, suggesting a potential mechanism for generating additional diversity from these GBF proteins...