Research Topics
| Peter JeschkeSummaryAffiliation: Bayer CropScience Country: Germany Publications
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Detail Information
Publications
Neonicotinoids-from zero to hero in insecticide chemistryPeter Jeschke
Bayer CropScience AG, Research Insecticides Chemistry Insecticides, Building 6240, Alfred Nobel Str 50, D 40789 Monheim am Rhein, Germany
Pest Manag Sci 64:1084-98. 2008..This review comprehensively describes particularly the origin, structure and bonding as well as associated properties of neonicotinoid insecticides...- Overview of the status and global strategy for neonicotinoidsPeter Jeschke
Research Insecticides Chemistry Insecticides, Building 6240, Bayer CropScience AG, Alfred Nobel Strasse 50, D 40789 Monheim am Rhein, Germany
J Agric Food Chem 59:2897-908. 2011..Innovative concepts for life-cycle management, jointly with the introduction of generic products, have made neonicotinoids the most important chemical class for the insecticide market... - The unique role of halogen substituents in the design of modern agrochemicalsPeter Jeschke
Bayer CropScience AG, Research Insecticides Chemistry Insecticides, Monheim am Rhein, Germany
Pest Manag Sci 66:10-27. 2010.... 
Synthesis and anthelmintic activity of cyclohexadepsipeptides with cyclohexylmethyl side chainsPeter Jeschke
Bayer CropScience AG, Research Insecticides, Chemistry Insecticides, Monheim am Rhein, Germany
Bioorg Med Chem Lett 17:3690-5. 2007..Here we report on a simple total synthesis of the precursors for this type of CHDPs and an efficient chemical transformation of the benzylic into the corresponding cyclohexylmethyl side chains...- Synthesis and anthelmintic activity of substituted (R)-phenyllactic acid containing cyclohexadepsipeptidesPeter Jeschke
Bayer CropScience AG, Research and Development, Chemistry Insecticides, Monheim am Rhein, Germany
Bioorg Med Chem Lett 16:4410-5. 2006..Here we report on a simple total synthetic pathway of the precursor for this particular type of CHDPs and an efficient modification of the benzylic side chain (R-PhLac(2))... - Cyclohexadepsipeptides (CHDPs) with improved anthelmintical efficacy against the gastrointestinal nematode (Haemonchus contortus) in sheepP Jeschke
Bayer CropScience AG, Research and Development Chemistry Insecticides, Alfred Nobel Strasse 50, Monheim am Rhein, Germany
Parasitol Res 97:S17-21. 2005..It may be assumed that the identified inflexible region of the major conformers might mimic the active conformation of these CHDPs, which could be helpful for rational design of anthelmintics with less complicated structures... - Influence of the cyclooctadepsipeptides PF1022A and PF1022E as natural products on the design of semi-synthetic anthelmintics such as emodepsideR Jeschke
Bayer CropScience AG, Research and Development, Chemistry lnsecticides, Alfred Nobel Strasse 50, Monheim am Rhein, Germany
Parasitol Res 97:S11-6. 2005.... - Synthesis and anthelmintic activity of 7-substituted 3,4a-dimethyl-4a,5a,8a,8b-tetrahydro-6H-pyrrolo[3',4':4,5]furo[3,2-b]pyridine-6,8(7H)-dionesPeter Jeschke
Bayer CropScience AG, Research Monheim, Global Chemistry Insecticides, Building 6240, Alfred Nobel Str 50, D 40789 Monheim am Rhein, Germany
Bioorg Med Chem Lett 15:2375-9. 2005..The absolute configuration of the most anthelmintically active (4aS,5aS,8aS,8bR)-enantiomer was determined by single crystal X-ray analysis using its stable (4aS,5aS,8aS,8bR)-enantiomer-CuCl2 (2:1)-complex... - The unique role of fluorine in the design of active ingredients for modern crop protectionPeter Jeschke
Bayer CropScience AG, BCS R GCI, Building 6240, Alfred Nobel Strasse 50, 40789 Monheim am Rhein, Germany
Chembiochem 5:571-89. 2004..Therefore, it is still difficult to predict the sites in a molecule at which fluorine substitution will result in optimal desired effects... - Synthesis and anthelmintic activity of cyclohexadepsipeptides with (S,S,S,R,S,R)-configurationPeter Jeschke
Bayer CropScience AG, Research Monheim, Global Chemistry Insecticides, Building Q18, D 51368 Leverkusen, Germany
Bioorg Med Chem Lett 13:3285-8. 2003..A correlation between the major conformer and its anthelmintic activity was found. Here, we report on a simple total synthetic pathway for this particular type of CHDPs... - Synthesis of anthelmintically active N-methylated amidoxime analogues of the cyclic octadepsipeptide PF1022APeter Jeschke
Bayer AG, Bayer CropScience, Research Global Chemistry Insecticides, Alfred Nobel Str 50, D 40789 Monheim, Germany
Pest Manag Sci 58:1205-15. 2002..Here we report on a specific modification at the N-methyl amide linkage by using the mono-thionated PF1022A, resulting in novel anthelmintically active backbone analogues of PF 1022A... - alpha-fluorinated ethers as "exotic" entity in medicinal chemistryPeter Jeschke
aBayer CropScience AG, BCS R I Chemistry Insecticides, Building 6240, Alfred Nobel Strasse 50, D 40789 Monheim, Germany
Mini Rev Med Chem 7:1027-34. 2007..The present review will give an overlook of its use in medicinal chemistry... - Synthesis and anthelmintic activity of thioamide analogues of cyclic octadepsipeptides such as PF1022AP Jeschke
Bayer AG, Crop Protection Business Group, Agricultural Centre Monheim, D 51368 Leverkusen, Germany
Pest Manag Sci 57:1000-6. 2001..Here we report on two different and simple synthetic pathways for this new class of thionated cyclic octadepsipeptides... - Alpha-fluorinated ethers, thioethers, and amines: anomerically biased speciesFrederic Leroux
Laboratoire de Stéréochimie associé au CNRS UMR 7008, Université Louis Pasteur ECPM, 25 rue Becquerel, F 67087 Strasbourg, France
Chem Rev 105:827-56. 2005 - PF1022A and related cyclodepsipeptides - a novel class of anthelminticsJurgen Scherkenbeck
Bayer AG, Leverkusen, Germany
Curr Top Med Chem 2:759-77. 2002.... - Alkaloids from stems and leaves of Stemona japonica and their insecticidal activitiesChun Ping Tang
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, People s Republic of China
J Nat Prod 71:112-6. 2008....