Xenofon Baraliakos

Summary

Country: Germany

Publications

  1. pmc Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Arthritis Res Ther 7:R439-44. 2005
  2. pmc The relationship between inflammation and new bone formation in patients with ankylosing spondylitis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Landgrafenstr, 15, 44652 Herne, Germany
    Arthritis Res Ther 10:R104. 2008
  3. doi request reprint Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Herne, Germany
    Ann Rheum Dis 73:710-5. 2014
  4. ncbi request reprint Withdrawal of biologic therapy in axial spondyloarthritis: the experience in established disease
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Germany
    Clin Exp Rheumatol 31:S43-6. 2013
  5. ncbi request reprint Safety and efficacy of readministration of infliximab after longterm continuous therapy and withdrawal in patients with ankylosing spondylitis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Herne Ruhr University, Bochum, Germany
    J Rheumatol 34:510-5. 2007
  6. ncbi request reprint Vertebral erosions associated with spinal inflammation in patients with ankylosing spondylitis identified by magnetic resonance imaging: changes after 2 years of tumor necrosis factor inhibitor therapy
    Xenofon Baraliakos
    From the Rheumazentrum Ruhrgebiet, Herne, Ruhr University Bochum German Rheumatism Research Center, Berlin and Department of Rheumatology, University of Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Rheumatol 40:1891-6. 2013
  7. ncbi request reprint Withdrawal of medical therapies in axial spondyloarthritis: what would be the optimal trial design?
    Uta Kiltz
    Rheumazentrum Ruhrgebiet, St Josefs Krankenhaus, Herne, Germany
    Clin Exp Rheumatol 31:S47-50. 2013
  8. doi request reprint Do patients with non-radiographic axial spondylarthritis differ from patients with ankylosing spondylitis?
    Uta Kiltz
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Arthritis Care Res (Hoboken) 64:1415-22. 2012
  9. doi request reprint Persistent clinical efficacy and safety of infliximab in ankylosing spondylitis after 8 years--early clinical response predicts long-term outcome
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Landgrafenstr 15, 44652 Herne, Germany
    Rheumatology (Oxford) 50:1690-9. 2011
  10. doi request reprint The natural course of radiographic progression in ankylosing spondylitis: differences between genders and appearance of characteristic radiographic features
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Landgrafenstr 15, 44652 Herne, Germany
    Curr Rheumatol Rep 13:383-7. 2011

Collaborators

Detail Information

Publications24

  1. pmc Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Arthritis Res Ther 7:R439-44. 2005
    ..Discontinuation of long-term therapy with infliximab eventually led to relapse of disease activity in all patients but one...
  2. pmc The relationship between inflammation and new bone formation in patients with ankylosing spondylitis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Landgrafenstr, 15, 44652 Herne, Germany
    Arthritis Res Ther 10:R104. 2008
    ..Whether and how spondylitis and syndesmophyte formation are linked are unclear. Our objective was to investigate whether and how spinal inflammation are associated with new bone formation in ankylosing spondylitis...
  3. doi request reprint Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Herne, Germany
    Ann Rheum Dis 73:710-5. 2014
    ..Compare the radiographic progression of ankylosing spondylitis (AS) patients treated with infliximab (INF) versus historical controls (Herne cohort, HC) never treated with tumour necrosis factor (TNF)-blockers over 8 years...
  4. ncbi request reprint Withdrawal of biologic therapy in axial spondyloarthritis: the experience in established disease
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Germany
    Clin Exp Rheumatol 31:S43-6. 2013
    ..This review summarises what is known on the topic of discontinuation of biologic treatment in patients with AS. ..
  5. ncbi request reprint Safety and efficacy of readministration of infliximab after longterm continuous therapy and withdrawal in patients with ankylosing spondylitis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Herne Ruhr University, Bochum, Germany
    J Rheumatol 34:510-5. 2007
    ....
  6. ncbi request reprint Vertebral erosions associated with spinal inflammation in patients with ankylosing spondylitis identified by magnetic resonance imaging: changes after 2 years of tumor necrosis factor inhibitor therapy
    Xenofon Baraliakos
    From the Rheumazentrum Ruhrgebiet, Herne, Ruhr University Bochum German Rheumatism Research Center, Berlin and Department of Rheumatology, University of Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Rheumatol 40:1891-6. 2013
    ..Spinal inflammation and erosions have been described in magnetic resonance imaging (MRI) examinations of patients with ankylosing spondylitis (AS). MRI scoring systems have implemented these observations...
  7. ncbi request reprint Withdrawal of medical therapies in axial spondyloarthritis: what would be the optimal trial design?
    Uta Kiltz
    Rheumazentrum Ruhrgebiet, St Josefs Krankenhaus, Herne, Germany
    Clin Exp Rheumatol 31:S47-50. 2013
    ..g. TNFi naïve patients or patients who will most likely remain in remission), when to restart and finally dose-adjustment after restart of the therapy. ..
  8. doi request reprint Do patients with non-radiographic axial spondylarthritis differ from patients with ankylosing spondylitis?
    Uta Kiltz
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Arthritis Care Res (Hoboken) 64:1415-22. 2012
    ..The differentiating features are incompletely understood...
  9. doi request reprint Persistent clinical efficacy and safety of infliximab in ankylosing spondylitis after 8 years--early clinical response predicts long-term outcome
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Landgrafenstr 15, 44652 Herne, Germany
    Rheumatology (Oxford) 50:1690-9. 2011
    ..To report for the first time on the efficacy and safety of anti-TNF therapy after 8 years of follow-up in patients with active AS, and analyse possible short-term predictors for long-term clinical outcomes...
  10. doi request reprint The natural course of radiographic progression in ankylosing spondylitis: differences between genders and appearance of characteristic radiographic features
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Landgrafenstr 15, 44652 Herne, Germany
    Curr Rheumatol Rep 13:383-7. 2011
    ..Female AS patients showed more cervical structural lesions, but male patients overall showed more rapid progress, leading us to conclude that dorsal vertebral edges do not add in depiction of radiographic deterioration in AS patients...
  11. ncbi request reprint Anti-TNF-alpha therapy with infliximab in spondyloarthritides
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Landgrafenstr 15, 44652 Herne, Germany
    Expert Rev Clin Immunol 6:9-19. 2010
    ..Serious adverse events on anti-TNF therapy have remained rare as these can be largely prevented by appropriate screening. The large benefits of anti-TNF therapy in AS seem to outweigh the few shortcomings of this treatment...
  12. pmc The effect of two golimumab doses on radiographic progression in ankylosing spondylitis: results through 4 years of the GO-RAISE trial
    Jurgen Braun
    Department of Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany
    Ann Rheum Dis 73:1107-13. 2014
    ..To evaluate radiographic progression in patients with ankylosing spondylitis (AS) receiving two different doses of the tumour necrosis factor antagonist golimumab...
  13. doi request reprint Treatment of ankylosing spondylitis and other spondyloarthritides
    Juergen Braun
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Curr Opin Rheumatol 21:324-34. 2009
    ..The purpose of this review was to collect all available information related to the treatment of ankylosing spondylitis published in the year 2008. This was achieved by a systematic literature search in PubMed...
  14. ncbi request reprint Biologic therapies for spondyloarthritis: what is new?
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Landgrafenstr 15, 44652 Herne, Germany
    Curr Rheumatol Rep 14:422-7. 2012
    ..The anti-IL-17a antibody secukinumab may be efficacious, on the basis of a proof-of-concept trial. Finally, first data on biosimilars of TNF blockers have recently been presented...
  15. doi request reprint Imaging in axial spondyloarthritis: diagnostic problems and pitfalls
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Rheum Dis Clin North Am 38:513-22. 2012
    ..Diagnosis of SpA should result from the combination of clinical, laboratory and imaging findings...
  16. pmc Golimumab reduces spinal inflammation in ankylosing spondylitis: MRI results of the randomised, placebo- controlled GO-RAISE study
    Jurgen Braun
    Rheumazentrum Ruhrgebiet, Herne, Ruhr University, Bochum, Germany
    Ann Rheum Dis 71:878-84. 2012
    ..To evaluate golimumab's effect on MRI-detected spinal inflammation in ankylosing spondylitis (AS)...
  17. doi request reprint OMERACT magnetic resonance imaging initiative on structural and inflammatory lesions in ankylosing spondylitis--report of a special interest group at OMERACT 10 on sacroiliac joint and spine lesions
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Landgrafenstr 15, 44652 Herne, Germany
    J Rheumatol 38:2051-4. 2011
    ....
  18. doi request reprint The natural course of radiographic progression in ankylosing spondylitis--evidence for major individual variations in a large proportion of patients
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Herne, Germany
    J Rheumatol 36:997-1002. 2009
    ..To describe the natural course of radiographic progression and to differentiate rates of progression in patients with ankylosing spondylitis (AS)...
  19. doi request reprint Opinion: Perspectives on imaging in axial spondyloarthritis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Landgrafenstrasse 15, 44652 Herne, Germany
    Nat Rev Rheumatol 9:498-502. 2013
    ..This Perspectives article provides an overview of the role of imaging in the diagnosis and management of axSpA, and also discusses open questions and future perspectives in this field. ..
  20. ncbi request reprint Tumor necrosis factor alpha antagonists in the treatment of axial spondyloarthritis
    Juergen Braun
    Rheumazentrum Ruhrgebiet, Landgrafenstr 15, 44652 Herne, Germany 49 2325 592 131 49 2325 592 136
    Expert Opin Investig Drugs 23:647-59. 2014
    ....
  21. doi request reprint Update of the literature review on treatment with biologics as a basis for the first update of the ASAS/EULAR management recommendations of ankylosing spondylitis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Landgrafenstr 15, 44652 Herne, Germany
    Rheumatology (Oxford) 51:1378-87. 2012
    ..To perform a literature review as basis for the update of the Assessment in SpondyloArthritis international Society/European League Against Rheumatism (ASAS/EULAR) treatment recommendations with biologics in AS...
  22. doi request reprint Spondyloarthritides
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Herne, Germany
    Best Pract Res Clin Rheumatol 25:825-42. 2011
    ..As far as it stands now, TNF blockers seem to have no influence on new bone formation in AS...
  23. doi request reprint Treatment of ankylosing spondylitis in patients refractory to TNF-inhibition: are there alternatives?
    Uta Kiltz
    Rheumazentrum Ruhrgebiet, St Josefs Krankenhaus, Landgrafenstr 15, 44652 Herne, Germany
    Curr Opin Rheumatol 24:252-60. 2012
    ..A variety of new drug classes have been investigated during the last years for the treatment of patients with AS in whom TNF blockers have failed or are contraindicated...
  24. doi request reprint Microsurgical nerve root decompression in scoliotic lumbar spines-the relationship between important anatomical structures in correlation to imaging and implications for daily practice: anatomic cadaveric study
    Amar Ali
    Institute for Spine Research, Ruhr University Bochum, Bochum, Germany
    J Neurosurg Spine 13:123-32. 2010
    ..These results confirm a topographic anatomical discrepancy. This knowledge can be used in daily perioperative practice for patients undergoing microsurgical decompression...