A Zittermann

Summary

Affiliation: Bad Oeynhausen
Country: Germany

Publications

  1. pmc Efficacy and safety of low-dose everolimus as maintenance immunosuppression in cardiac transplant recipients
    Uwe Fuchs
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstraße 11, 32545 Bad Oeynhausen, Germany
    J Transplant 2012:976921. 2012
  2. doi request reprint Body mass index, cardiac surgery and clinical outcome. A single-center experience with 9125 patients
    A Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany Electronic address
    Nutr Metab Cardiovasc Dis 24:168-75. 2014
  3. ncbi request reprint Vitamin D supplementation, body weight and human serum 25-hydroxyvitamin D response: a systematic review
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Centre North Rhine Westphalia NRW, Ruhr University Bochum, GeorgStr 11, 32545, Bad Oeynhausen, Germany
    Eur J Nutr 53:367-74. 2014
  4. pmc Magnesium deficit ? overlooked cause of low vitamin D status?
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westphalia, Ruhr University of Bochum, Georgstra e 11, 32545, Bad Oeynhausen Germany
    BMC Med 11:229. 2013
  5. doi request reprint Vitamin D status and the risk of major adverse cardiac and cerebrovascular events in cardiac surgery
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstrasse 11, Bad Oeynhausen, Germany
    Eur Heart J 34:1358-64. 2013
  6. doi request reprint Association between glomerular filtration rate and 1,25-dihydroxyvitamin D in cardiac surgery
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstrasse, Bad Oeynhausen, Germany
    Scand Cardiovasc J 46:359-65. 2012
  7. ncbi request reprint Safety issues of vitamin D supplementation
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstraße 11, 32545 Bad Oeynhausen, Germany
    Anticancer Agents Med Chem 13:4-10. 2013
  8. doi request reprint Future directions in vitamin D and cardiovascular research
    A Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstraße 11, Bad Oeynhausen, Germany
    Nutr Metab Cardiovasc Dis 22:541-6. 2012
  9. pmc Nonclassical vitamin D action
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstrasse 11, 32545 Bad Oeynhausen, Germany
    Nutrients 2:408-25. 2010
  10. doi request reprint Parameters of mineral metabolism predict midterm clinical outcome in end-stage heart failure patients
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstrasse 11, Bad Oeynhausen, Germany
    Scand Cardiovasc J 45:342-8. 2011

Detail Information

Publications98

  1. pmc Efficacy and safety of low-dose everolimus as maintenance immunosuppression in cardiac transplant recipients
    Uwe Fuchs
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstraße 11, 32545 Bad Oeynhausen, Germany
    J Transplant 2012:976921. 2012
    ..1% of patients in the RD group (P = 0.361). Biochemical safety parameters were comparable in both groups. Our results indicate that low-dose EVL may be as effective and safe as regular dose EVL...
  2. doi request reprint Body mass index, cardiac surgery and clinical outcome. A single-center experience with 9125 patients
    A Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany Electronic address
    Nutr Metab Cardiovasc Dis 24:168-75. 2014
    ..In cardiac surgical patients, the effect of BMI on mortality and major adverse cardiac and cerebrovascular events (MACCE) is not completely clear...
  3. ncbi request reprint Vitamin D supplementation, body weight and human serum 25-hydroxyvitamin D response: a systematic review
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Centre North Rhine Westphalia NRW, Ruhr University Bochum, GeorgStr 11, 32545, Bad Oeynhausen, Germany
    Eur J Nutr 53:367-74. 2014
    ..We therefore aimed to investigate the importance of body weight for the dose-response relation in circulating 25OHD...
  4. pmc Magnesium deficit ? overlooked cause of low vitamin D status?
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westphalia, Ruhr University of Bochum, Georgstra e 11, 32545, Bad Oeynhausen Germany
    BMC Med 11:229. 2013
    ..Please see related research article: http://www.biomedcentral.com/1741-7015/11/187...
  5. doi request reprint Vitamin D status and the risk of major adverse cardiac and cerebrovascular events in cardiac surgery
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstrasse 11, Bad Oeynhausen, Germany
    Eur Heart J 34:1358-64. 2013
    ..We aimed to investigate the association of pre-operative 25-hydroxyvitamin D (25(OH)D) levels with major cardiac and cerebrovascular events (MACCE) in cardiac surgical patients...
  6. doi request reprint Association between glomerular filtration rate and 1,25-dihydroxyvitamin D in cardiac surgery
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstrasse, Bad Oeynhausen, Germany
    Scand Cardiovasc J 46:359-65. 2012
    ..Renal impairment is a risk factor for poor clinical outcome in cardiac surgical patients and low circulating levels of the vitamin D hormone 1,25-dihydroxyvitamin D (1,25[OH](2)D) may contribute to this risk...
  7. ncbi request reprint Safety issues of vitamin D supplementation
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstraße 11, 32545 Bad Oeynhausen, Germany
    Anticancer Agents Med Chem 13:4-10. 2013
    ....
  8. doi request reprint Future directions in vitamin D and cardiovascular research
    A Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstraße 11, Bad Oeynhausen, Germany
    Nutr Metab Cardiovasc Dis 22:541-6. 2012
    ..Final confirmation for a causal relationship between vitamin D and CVD is however still lacking. The present viewpoint article outlines several future research directions to close this gap...
  9. pmc Nonclassical vitamin D action
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstrasse 11, 32545 Bad Oeynhausen, Germany
    Nutrients 2:408-25. 2010
    ..Thus, there is a need to recommend a vitamin D intake that is effective for achieving adequate circulating 25-hydroxyvitamin D concentrations (>75 nmol/L)...
  10. doi request reprint Parameters of mineral metabolism predict midterm clinical outcome in end-stage heart failure patients
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Georgstrasse 11, Bad Oeynhausen, Germany
    Scand Cardiovasc J 45:342-8. 2011
    ..We investigated to which extent disturbances in mineral metabolism predict 90-day clinical outcome in end-stage heart failure patients...
  11. pmc A randomized controlled trial on the efficacy of carbohydrate-reduced or fat-reduced diets in patients attending a telemedically guided weight loss program
    Sabine Frisch
    Klinik für Thorax und Kardiovaskularchirurgie, Herzzentrum NRW, Ruhr Universitat Bochum, Bad Oeynhausen, Germany
    Cardiovasc Diabetol 8:36. 2009
    ..We investigated whether macronutrient composition of energy-restricted diets influences the efficacy of a telemedically guided weight loss program...
  12. doi request reprint Calcitriol deficiency and 1-year mortality in cardiac transplant recipients
    Armin Zittermann
    Klinik für Thorax und Kardiovaskularchirurgie, Herz und Diabeteszentrum NRW, Ruhr Universitat Bochum, Georgstrasse 11, D 32545 Bad Oeynhausen, Germany
    Transplantation 87:118-24. 2009
    ..We investigated whether lower serum calcitriol concentrations are associated with increased 1-year mortality in cardiac transplant recipients...
  13. doi request reprint Vitamin D supplementation enhances the beneficial effects of weight loss on cardiovascular disease risk markers
    Armin Zittermann
    Klinik für Thorax und Kardiovaskularchirurgie and Institut für Laboratoriums und Transfusionsmedizin, Herzzentrum NRW, Ruhr Universitat Bochum, Bad Oeynhausen, Germany
    Am J Clin Nutr 89:1321-7. 2009
    ..However, there is also evidence that calcitriol increases lipogenesis and decreases lipolysis...
  14. doi request reprint Vitamin D in the prevention and treatment of coronary heart disease
    Armin Zittermann
    Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westfalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    Curr Opin Clin Nutr Metab Care 11:752-7. 2008
    ..In addition, human data associating serum vitamin D metabolite levels or oral vitamin D dosages or both with coronary heart disease outcome parameters are reviewed...
  15. doi request reprint Protective and toxic effects of vitamin D on vascular calcification: clinical implications
    Armin Zittermann
    Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westfalia, University Hospital of Ruhr University Bochum, Georgstrasse 11, 32545 Bad Oeynhausen, Germany
    Mol Aspects Med 29:423-32. 2008
    ..Future studies should focus on the impact of vitamin D deficiency on VC and clinical outcome in these groups...
  16. doi request reprint Poor outcome in end-stage heart failure patients with low circulating calcitriol levels
    Armin Zittermann
    Klinik für Thorax und Kardiovaskularchirurgie, Herz und Diabeteszentrum NRW, Ruhr Universitat Bochum, Georgstrasse 11, D 32545 Bad Oeynhausen, Germany
    Eur J Heart Fail 10:321-7. 2008
    ..Vitamin D receptor knockout mice develop typical signs of congestive heart failure (CHF). In approximately 20% of stable CHF patients, frankly low concentrations of the vitamin D hormone calcitriol are found...
  17. ncbi request reprint Patients with congestive heart failure and healthy controls differ in vitamin D-associated lifestyle factors
    Armin Zittermann
    Klinik für Thorax und Kardiovaskularchirurgie, Herz und Diabeteszentrum NRW, Ruhr Universitat Bochum, Georgstrasse 11, D 32545 Bad Oeynhausen, Germany
    Int J Vitam Nutr Res 77:280-8. 2007
    ..001). Our results demonstrate that CHF patients and controls differed in several vitamin D-associated lifestyle factors and in alcohol consumption during earlier periods of their lives...
  18. ncbi request reprint Markers of bone metabolism in congestive heart failure
    Armin Zittermann
    Department of Cardio Thoracic Surgery, Heart Center Northrhine Westfalia, Ruhr University of Bochum, Georgstrasse 11, 32545 Bad Oeynhausen, Germany
    Clin Chim Acta 366:27-36. 2006
    ..Preventive strategies are able to normalize bone metabolism and to attenuate the high bone loss during the first year after heart transplantation...
  19. ncbi request reprint Vitamin D and disease prevention with special reference to cardiovascular disease
    Armin Zittermann
    Department of Cardio Thoracic Surgery, Heart Center North Rhine Westfalia, Ruhr University of Bochum, Bad Oeynhausen, Georgstrasse 11, 32545, Germany
    Prog Biophys Mol Biol 92:39-48. 2006
    ..As a consequence, legislation has to be changed to allow higher amounts of vitamin D in fortified foods and supplements...
  20. ncbi request reprint Vitamin D and vascular calcification
    Armin Zittermann
    Department of Cardiothoracic Surgery, Northrhine Westfalia Heart Center, Ruhr University Bochum, Bad Oeynhausen, Germany
    Curr Opin Lipidol 18:41-6. 2007
    ..The effects of vitamin D excess and deficiency on vascular calcification are reviewed in this article...
  21. doi request reprint Circulating calcitriol concentrations and total mortality
    Armin Zittermann
    Department of Cardio Thoracic Surgery, Heart Center North Rhine Westfalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    Clin Chem 55:1163-70. 2009
    ..We therefore evaluated the predictive value of circulating calcitriol for midterm mortality in patients of a specialized heart center...
  22. ncbi request reprint Vitamin D and the adaptive immune system with special emphasis to allergic reactions and allograft rejection
    Armin Zittermann
    Heart Center North Rhine Westphalia, University Hospital, Ruhr University Bochum, Bad Oeynhausen, Germany
    Inflamm Allergy Drug Targets 8:161-8. 2009
    ..In this context, current strategy of vitamin D supplementation in infants and the possibility of a bimodal effect on allergic reactions of both, vitamin D deficiency and excess are discussed...
  23. doi request reprint Vitamin D deficiency and mortality
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westfalia, Ruhr University Bochum, Georgstrsse 11, D 32545 Bad Oeynhausen, Germany
    Curr Opin Clin Nutr Metab Care 12:634-9. 2009
    ..Deficient 25(OH)D concentrations (<25 nmol/l) are prevalent in Europe and North America...
  24. doi request reprint Sun, vitamin D, and cardiovascular disease
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    J Photochem Photobiol B 101:124-9. 2010
    ..Nevertheless, future randomised clinical trials are needed to evaluate whether vitamin D is effective with respect to primary, secondary, and/or tertiary prevention of CVD...
  25. ncbi request reprint Low vitamin D status is associated with low cord blood levels of the immunosuppressive cytokine interleukin-10
    Armin Zittermann
    Department of Nutrition Science, University of Bonn, Bonn, Germany
    Pediatr Allergy Immunol 15:242-6. 2004
    ..We conclude that the low vitamin D status of infants born in winter may at least in part adversely affect biomarkers of allergy risk...
  26. doi request reprint The estimated benefits of vitamin D for Germany
    A Zittermann
    Clinic for Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    Mol Nutr Food Res 54:1164-71. 2010
    ..To achieve this goal, the daily production of at least 25 microg of vitamin D in the skin or an equivalent oral intake should be guaranteed...
  27. doi request reprint Vitamin D deficiency is an independent predictor of anemia in end-stage heart failure
    Armin Zittermann
    Department of Cardio Thoracic Surgery, Heart Center North Rhine Westphalia, Ruhr University Bochum, Georgstraße 11, 32545 Bad Oeynhausen, Germany
    Clin Res Cardiol 100:781-8. 2011
    ..Prospective randomized studies with administration of vitamin D (metabolites) will have to clarify if the association of vitamin D deficiency with anemia is causal...
  28. ncbi request reprint The role of vitamin D in dyslipidemia and cardiovascular disease
    Armin Zittermann
    Clinic for Thoracic and Cardiovascular Surgery Heart Center North Rhine Westphalia Ruhr University Bochum Georgstraße 11, Bad Oeynhausen, Germany
    Curr Pharm Des 17:933-42. 2011
    ..Adequately designed randomised controlled trials investigating the dose-response effect of vitamin D on different CVD outcome parameters are now warranted...
  29. ncbi request reprint Combined calcium and vitamin D supplementation is not superior to calcium supplementation alone in improving disturbed bone metabolism in patients with congestive heart failure
    S S Schleithoff
    Institute of Nutrition and Food Sciences, University of Bonn, Germany
    Eur J Clin Nutr 62:1388-94. 2008
    ..To clarify the potential role of vitamin D supplementation on bone metabolism in congestive heart failure (CHF) patients with low vitamin D status and insufficient dietary calcium intake...
  30. doi request reprint Simultaneous aortic and mitral valve replacement in octogenarians: a viable option?
    Ariane Maleszka
    Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westfalia, University Hospital of Ruhr University Bochum, Bad Oeynhausen, Germany
    Ann Thorac Surg 86:1804-8. 2008
    ..Few reliable data are available on clinical outcome of octogenarians undergoing simultaneous aortic and mitral valve replacement...
  31. ncbi request reprint Physiologic fluctuations of serum estradiol levels influence biochemical markers of bone resorption in young women
    A Zittermann
    Department of Nutrition Science, University of Bonn, Germany
    J Clin Endocrinol Metab 85:95-101. 2000
    ..The data suggest that normal menstrual cycling in young women is associated with monthly fluctuations in bone turnover. This physiological effect of the menstrual cycle is most probably related to variations in serum E2 concentrations...
  32. ncbi request reprint Diffusion-weighted magnetic resonance imaging for the detection of ischemic brain lesions in coronary artery bypass graft surgery: relation to extracorporeal circulation and heparinization
    N Mirow
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Bad, Oeynhausen, Germany
    J Cardiovasc Surg (Torino) 52:117-26. 2011
    ..We investigated whether the design of extracorporeal circulation (ECC) and the extent of perioperative heparinization have an impact on neurological dysfunction...
  33. ncbi request reprint Wheat bran supplementation does not affect biochemical markers of bone turnover in young adult women with recommended calcium intake
    A Zittermann
    Department of Nutrition Science, University of Bonn, Germany
    Br J Nutr 82:431-5. 1999
    ....
  34. ncbi request reprint Body mass index and disease duration are predictors of disturbed bone turnover in anorexia nervosa. A case-control study
    T Weinbrenner
    Department of Clinical Pharmacology, University of Bonn, Germany
    Eur J Clin Nutr 57:1262-7. 2003
    ..To characterize the influence of body mass index (BMI), body composition, hormonal factors and disease duration on bone metabolism markers in anorexia nervosa (AN) patients...
  35. ncbi request reprint Lactose does not enhance calcium bioavailability in lactose-tolerant, healthy adults
    A Zittermann
    Department of Nutrition Science, University of Bonn, Germany
    Am J Clin Nutr 71:931-6. 2000
    ..There is evidence from animal studies that lactose has a beneficial effect on intestinal calcium absorption. However, data concerning the effect of lactose on calcium absorption in lactose-tolerant adults are inconclusive...
  36. ncbi request reprint Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial
    Stefanie S Schleithoff
    Institute of Nutrition and Food Science, University of Bonn, Bonn, Germany
    Am J Clin Nutr 83:754-9. 2006
    ..In vitro studies suggest that vitamin D suppresses proinflammatory cytokines and increases antiinflammatory cytokines...
  37. ncbi request reprint Frequent detection of hepatitis B core antibodies in heart transplant recipients without preceding hepatitis B infection
    G Tenderich
    Klinik für Thorax und Kardiovaskularchirurgie, Herz und Diabeteszentrum NRW, Bad Oeynhausen, Germany
    Transplant Proc 37:4522-4. 2005
    ..Moreover, our data demonstrated that the presence of anti-HBc in heart recipients frequently occurs but does not necessarily indicate a preceding HBV infection...
  38. ncbi request reprint Evidence for an acute rise of intestinal calcium absorption in response to aerobic exercise
    A Zittermann
    Department of Nutrition Science, University of Bonn, Endenicher Allee 11 13, Germany
    Eur J Nutr 41:189-96. 2002
    ..The acute effects of physical activity on intestinal calcium (Ca) uptake and on bone metabolism are not known...
  39. ncbi request reprint Vitamin D in preventive medicine: are we ignoring the evidence?
    Armin Zittermann
    Department of Nutrition Science, University of Bonn, Endenicher Allee 11 13, 53115 Bonn, Germany
    Br J Nutr 89:552-72. 2003
    ..The oral dose necessary to achieve adequate serum 25(OH)D levels is probably much higher than the current recommendations of 5-15 microg/d...
  40. ncbi request reprint Low serum levels of intact osteocalcin in patients with congestive heart failure
    Stefanie Schulze Schleithoff
    Department of Nutrition Science, University of Bonn, Endenicher Allee 11 13, 53115 Bonn, Germany
    J Bone Miner Metab 21:247-52. 2003
    ..However, the low serum levels of intact osteocalcin and the high ratio of undercarboxylated-to-intact osteocalcin deserve further consideration...
  41. doi request reprint Moderate dosage of tranexamic acid during cardiac surgery with cardiopulmonary bypass and convulsive seizures: incidence and clinical outcome
    A Koster
    Institute for Anaesthesiology, Heart and Diabetes Centre North Rhine Westphalia, Ruhr University Bochum, GeorgStr 11, D 32545 Bad Oeynhausen, Germany
    Br J Anaesth 110:34-40. 2013
    ..Recent investigations indicate an up to seven-fold increase in CS in cardiac surgical patients receiving high doses (≥60 mg kg(-1) body weight) of tranexamic acid (TA)...
  42. ncbi request reprint Preoperative haemostasis testing does not predict requirement of blood products in cardiac surgery
    W Prohaska
    Institut für Laboratoriums and Transfusionsmedizin, Herz und Diabeteszentrum Nordrhein Westfalen, Universitatsklinik der Ruhr Universitat Bochum, Goethestr 11, 32545 Bad Oeynhausen, Germany
    Eur J Med Res 13:525-30. 2008
    ..Since their diagnostic efficacy is often low, routinely performed haemostasis testing has been questioned. We investigated whether preoperatively assessed haemostasis testing can be used to predict the requirement of blood products...
  43. doi request reprint Bosentan effects on hemodynamics and clinical outcome in heart failure patients with pulmonary hypertension awaiting cardiac transplantation
    T Hefke
    Department of Cardio Thoracic Surgery, Heart Center NRW, Bad Oeynhausen, Germany
    Thorac Cardiovasc Surg 60:26-34. 2012
    ..We assessed whether low dose treatment with the dual endothelin-1 receptor antagonist bosentan is associated with improved hemodynamics and clinical outcome in these patients...
  44. ncbi request reprint Effects of vitamin K on calcium and bone metabolism
    A Zittermann
    Department of Nutrition Science, University of Bonn, Germany
    Curr Opin Clin Nutr Metab Care 4:483-7. 2001
    ..In contrast, therapy with very high pharmacological doses of the vitamin K2 menatetrenone has impressively been used to prevent further bone mineral loss and fracture risk in osteoporotic patients...
  45. ncbi request reprint Carbamazepine does not alter biochemical parameters of bone turnover in healthy male adults
    S Brämswig
    Department of Clinical Pharmacology, University of Bonn, 53105 Bonn, Germany
    Calcif Tissue Int 73:356-60. 2003
    ..Variations in 25OHD levels are in line with the seasonal fluctuations in vitamin D status...
  46. doi request reprint Clinical outcome in cardiac transplant recipients receiving tacrolimus retard
    U Fuchs
    Clinic for Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    Transplant Proc 45:2000-4. 2013
    ..Nevertheless, the required dose of TAC retard for achieving acceptable blood trough levels should be investigated in more detail...
  47. doi request reprint Erdheim-Chester disease in a female cardiac surgery patient
    H R Mahoozi
    Clinic for Thoracic and Cardiovascular Surgery, Heart Center NRW, Bad Oeynhausen, Germany
    Thorac Cardiovasc Surg 60:428-30. 2012
    ..We conclude that isolated cardiac ECD should be included in the surgical strategy for cardiac tumors showing infiltrative growth...
  48. ncbi request reprint Reconstructive surgery for an akinetic anterior ventricular wall in ischemic cardiomyopathy
    Masataka Yoda
    Department of Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westphalia, Ruhr University of Bochum, Germany
    Ann Thorac Cardiovasc Surg 15:227-32. 2009
    ....
  49. doi request reprint Everolimus plus dosage reduction of cyclosporine in cardiac transplant recipients with chronic kidney disease: a two-year follow-up study
    U Fuchs
    Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    Transplant Proc 43:1839-46. 2011
    ..In summary, EVL combined with low-dose CSA had modest beneficial effects on kidney function in heart transplant recipients with CKD stages 3-4. A significant percentage of patients had to stop EVL because of various adverse events...
  50. ncbi request reprint A risk score to predict 30-day mortality in patients with intra-aortic balloon pump implantation
    D Saeed
    Department of Cardiothoracic Surgery, Heart Center North Rhine Westphalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    Thorac Cardiovasc Surg 55:163-7. 2007
    ..Several risk factors for early mortality after intra-aortic balloon pump (IABP) implantation have been described...
  51. ncbi request reprint Short-term effects of high soy supplementation on sex hormones, bone markers, and lipid parameters in young female adults
    Armin Zittermann
    Department of Nutrition Science, University of Bonn, Endenicher Allee 11 13, 53115 Bonn, Germany
    Eur J Nutr 43:100-8. 2004
    ..High intake of soy products has been suggested to prevent breast cancer, osteoporosis, and cardiovascular diseases...
  52. ncbi request reprint Vitamin D insufficiency in congestive heart failure: why and what to do about it?
    Armin Zittermann
    Klinik für Thorax und Kardiovaskularchirurgie, Herzzentrum Nordrhein Westfalen, Ruhr Universitat Bochum, Bad Oeynhausen, Germany
    Heart Fail Rev 11:25-33. 2006
    ..At present, daily oral intake of 50-100 microg vitamin D seems to be the most effective way to improve vitamin D status in CHF patients...
  53. ncbi request reprint Low vitamin D status: a contributing factor in the pathogenesis of congestive heart failure?
    Armin Zittermann
    Department of Nutrition Science, University of Bonn, Germany
    J Am Coll Cardiol 41:105-12. 2003
    ..This study was designed to evaluate the association between vitamin D status and congestive heart failure (CHF)...
  54. ncbi request reprint No evidence for an improvement of long-term survival by HLA matching in heart transplant recipients
    G Tenderich
    Heart Center North Rhine Westfalia, Georgstrasse 11, 32545 Bad Oeynhausen, Germany
    Transplant Proc 39:1575-9. 2007
    ..However, several pretransplant factors and transplant era were independently associated with mortality risk...
  55. ncbi request reprint Unusual case of an 18-year-old heart transplant recipient with endocardial fibroelastosis
    U Fuchs
    Heart Center North Rhine Westfalica, Department of Cardio Thoracic Surgery, Ruhr University of Bochum, Bad Oeynhausen, and Department of Pathology, Municipal Hospital of Bielefeld, Germany
    Transplant Proc 38:1511-3. 2006
    ..Autopsies of the explanted heart revealed massive endomyocardial fibroelastosis. We concluded that endomyocardial fibroelastosis has to be considered a cause of heart failure in young adults with unclear cardiomyopathy...
  56. ncbi request reprint Nitrogen metabolism and bone metabolism markers in healthy adults during 16 weeks of bed rest
    K Scheld
    Department of Nutrition Science, University of Bonn, Endenicher Allee 11-13, 53115 Bonn, Germany
    Clin Chem 47:1688-95. 2001
    ..These changes appear in association with the onset of a negative nitrogen balance, but decreased bone collagen synthesis and enhanced collagen breakdown occur after a time lag of several weeks...
  57. doi request reprint [A telemetrically-guided program for weight reduction in overweight subjects (the SMART study)]
    H Körtke
    Klinik für Thorax u Kardiovaskularchirurgie, Herz u Diabeteszentrum NRW, Bad Oeynhausen, Universitat Bochum
    Dtsch Med Wochenschr 133:1297-303. 2008
    ..Compliance with weight reducing programs can be improved by intensive care and control. We tested a telemetrically-guided weight reduction program in overweight and obese persons...
  58. doi request reprint Impact of prior percutaneous coronary intervention on the outcome of coronary artery bypass surgery: a multicenter analysis
    Parwis Massoudy
    Department of Thoracic and Cardiovascular Surgery, West German Heart Center Essen, Essen, Germany
    J Thorac Cardiovasc Surg 137:840-5. 2009
    ..Do prior percutaneous coronary interventions adversely affect the outcome of subsequent coronary artery bypass grafting? We investigated this effect on a multicenter basis...
  59. ncbi request reprint Immunosuppressive therapy with everolimus can be associated with potentially life-threatening lingual angioedema
    Uwe Fuchs
    Heart Center Northrhine Westfalia, Department of Cardio Thoracic Surgery, Ruhr University of Bochum, D 32545 Bad Oeynhausen, Germany
    Transplantation 79:981-3. 2005
    ..We conclude that the potentially life-threatening condition of lingual angioedema should be considered a severe drug reaction after initiation of everolimus therapy in heart transplant recipients...
  60. ncbi request reprint Heart transplantation in a 68-year-old patient with senile systemic amyloidosis
    Uwe Fuchs
    Heart Center North Rhine Westfalia, Department of Cardio Thoracic Surgery, Ruhr University of Bochum, Bad Oeynhausen, Germany
    Am J Transplant 5:1159-62. 2005
    ..At the 2-year follow-up, the patient's physical and mental health was excellent. We conclude that heart transplantation can be an effective treatment in progressive heart failure due to SSA...
  61. ncbi request reprint Clinical outcome of patients with deep sternal wound infection managed by vacuum-assisted closure compared to conventional therapy with open packing: a retrospective analysis
    Uwe Fuchs
    Department of Cardiothoracic Surgery, Heart Center North Rhine Westfalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    Ann Thorac Surg 79:526-31. 2005
    ..We therefore compared clinical outcome of patients whose sternal infection was managed with the vacuum-assisted closure system or with the conventional procedure of open packing...
  62. doi request reprint Efficacy and safety of very low-dose self-management of oral anticoagulation in patients with mechanical heart valve replacement
    Heinrich Koertke
    Clinic for Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    Ann Thorac Surg 90:1487-93. 2010
    ..Self-management improves oral anticoagulation control. Here we provide data of a preplanned interim analysis of very low-dose early self-controlled anticoagulation...
  63. ncbi request reprint Reoperation of the aortic valve in octogenarians
    Thomas Eitz
    Department of Cardiothoracic Surgery, Heart and Diabetes Center NRW, North Rhine Westfalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    Ann Thorac Surg 82:1385-90. 2006
    ..Reliable data on mortality and risk factors in octogenarians after replacement of aortic valve prostheses are scanty, however...
  64. ncbi request reprint [Surgical management of aortic valve stenosis]
    Georg Kleikamp
    Klinik für Thorax und Kardiovaskularchirurgie, Herz und Diabeteszentrum NRW, Universitatsklinik der Ruhr Universitat Bochum, Georgstrasse 11, 32545 Bad Oeynhausen
    Herz 31:670-5. 2006
    ..All newly developed procedures for the treatment of aortic stenosis therefore will have to prove their superiority in future...
  65. ncbi request reprint Clinical outcome of heart transplant recipients receiving tacrolimus with or without mycophenolate mofetil
    Uwe Fuchs
    Department of Cardio Thoracic Surgery, Heart Center, North Rhine Westfalia, Ruhr University of Bochum, Oeynhausen, Germany
    Clin Transplant 20:450-6. 2006
    ..Consequently, no general recommendation can be given at present whether TAC should be combined with MMF or with cortisone in heart transplant recipients...
  66. doi request reprint Mitral regurgitation--evaluation of a multidimensional echocardiographic grading system. A study on 177 patients with chronic primary and secondary mitral regurgitation
    Christoph Langer
    Department of Cardiology, Heart and Diabetes Centre North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    Scand Cardiovasc J 43:311-7. 2009
    ..With regard to chronic primary and secondary MR the purpose of this study was to compare a new multi-dimensional echo-based grading system with an independent pre-operatively used invasive standard...
  67. ncbi request reprint Comparison of sirolimus and everolimus in their effects on blood lipid profiles and haematological parameters in heart transplant recipients
    Gero Tenderich
    Department of Cardio Thoracic Surgery, Heart Center North Rhine Westfalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    Clin Transplant 21:536-43. 2007
    ....
  68. ncbi request reprint Low-dose international normalized ratio self-management: a promising tool to achieve low complication rates after mechanical heart valve replacement
    Heinrich Koertke
    Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia Bad Oeynhausen, Germany Clinic, Ruhr University Bochum, Bochum, Germany
    Ann Thorac Surg 79:1909-14; discussion 1914. 2005
    ..5. This study evaluated the compliance, clinical complications, and survival of patients after mechanical heart valve replacement with low-dose INR self-management compared with conventional-dose anticoagulation...
  69. doi request reprint Cardiac resynchronization therapy: long-term alternative to cardiac transplantation?
    Bert Hansky
    Department of Cardio Thoracic Surgery, Heart and Diabetes Center North Rhine Westfalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    Ann Thorac Surg 87:432-8. 2009
    ..Cardiac transplantation remains the gold standard for treating end-stage heart failure. However, because of donor shortage and posttransplant complications alternative options are needed...
  70. ncbi request reprint Mitroflow synergy prostheses for aortic valve replacement: 19 years experience with 1,516 patients
    Kazutomo Minami
    Department of Cardiothoracic Surgery, Heart Center Northrhine Westfalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    Ann Thorac Surg 80:1699-705. 2005
    ..The aim of this article is to describe the clinical long-term performance of the Mitroflow Synergy pericardial valve (Sorin Group Inc, Mitroflow Division, Vancouver, Canada) in the aortic position for as long as 19 years...
  71. ncbi request reprint Low-dose oral anticoagulation in patients with mechanical heart valve prostheses: final report from the early self-management anticoagulation trial II
    Heinrich Koertke
    Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia Bad Oeynhausen, University Hospital of the Ruhr University of Bochum, Georgstr 11 32545, Bad Oeynhausen, Germany
    Eur Heart J 28:2479-84. 2007
    ..Here, we present data on the safety of low-dose INR self-management...
  72. ncbi request reprint A multidisciplinary network to save the lives of severe, persistent cardiogenic shock patients
    Aly El-Banayosy
    Department of Cardiothoracic Surgery, Heart Center North Rhine Westfalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    Ann Thorac Surg 80:543-7. 2005
    ..We therefore tried to improve the outcome of these patients using a network between local hospitals and a specialized heart center that has facilities for transplantation and ventricular assist device (VAD) implantation...
  73. doi request reprint Is torsion a suitable echocardiographic parameter to detect acute changes in left ventricular afterload in children?
    Kai Thorsten Laser
    Center of Congenital Heart Disease, Heart and Diabetes Center Northrhine Westfalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    J Am Soc Echocardiogr 22:1121-8. 2009
    ..Congenital heart defects such as coarctation or valvular aortic stenosis are followed by changes in left ventricular myocardial deformation mechanics induced by pressure overload...
  74. ncbi request reprint New East-Westfalian Postoperative Therapy Concept: a telemedicine guide for the study of ambulatory rehabilitation of patients after cardiac surgery
    Heinrich Körtke
    Klinik für Thorax und Kardiovaskularchirurgie, Herzzentrum Nordrhein Westfalen, Georgstrasse 11, 32545 Bad Oeynhausen, Germany
    Telemed J E Health 12:475-83. 2006
    ..Our data indicate that home-based rehabilitation is more effective than in-hospital rehabilitation for patients after cardiac surgery...
  75. ncbi request reprint Putting cardiovascular disease and vitamin D insufficiency into perspective
    Armin Zittermann
    Department of Cardio Thoracic Surgery, Heart Center North Rhine Westfalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    Br J Nutr 94:483-92. 2005
    ..However, more controlled clinical trials are needed to investigate whether optimal oral vitamin D supplementation is able to reduce CVD morbidity and mortality...
  76. ncbi request reprint Noninvasive echocardiographic estimation of pulmonary wedge pressure in candidates for and recipients of heart transplantation
    Gero Tenderich
    Department of Cardio Thoracic Surgery, Heart Center North Rhine Westfalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    J Am Soc Echocardiogr 20:480-5. 2007
    ..We assessed the value of deceleration time (dt) of diastolic wave of pulmonary venous flow (PVF) (PVF_dt) as noninvasive estimation of pulmonary wedge pressure (PWP) in candidates for and recipients of heart transplantation...
  77. ncbi request reprint Prevalent platelet dysfunction in patients with aortic valve disease
    Wolfgang Prohaska
    Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center North Rhine Westfalia, University Hospital of the Ruhr, University Bochum, Bad Oeynhausen, Germany
    J Heart Valve Dis 17:542-7. 2008
    ..As a consequence, blood flow is disturbed and a stimulation of components of the hemostasis system is assumed. The possible mechanisms of this process are, however, unclear at present...
  78. ncbi request reprint [Predictive value of ECG changes for acute cardiac rejections in heart transplant recipients]
    Gero Tenderich
    Klinik für Thorax und Kardiovaskularchirurgie, Ruhr Universitat Bochum, Herzzentrum Nordrhein Westfalen, Georgstrasse 11, 32545 Bad Oeynhausen
    Med Klin (Munich) 101:99-106. 2006
    ..However, as an invasive procedure it is associated with a definite risk for complications. Therefore, it was examined whether changes in QT time and QT dispersion on the surface ECG are able to predict an acute cellular rejection...
  79. ncbi request reprint [New Eastern Westfalian Postoperative Therapeutic Concept (NOPT). A telemedically guided study for ambulatory rehabilitation of patients after cardiac surgery]
    Heinrich Körtke
    Klinik für Thorax und Kardiovaskularchirurgie, Herzzentrum Nordrhein Westfalen, Bad Oeynhausen
    Med Klin (Munich) 100:383-9. 2005
    ..Therefore, the possibility of a telemedically monitored rehabilitation at home as an alternative to an in-hospital rehabilitation was evaluated in a pilot study...
  80. ncbi request reprint [Structural valve deterioration of aortic bioprostheses and reoperation in octogenarians. Results and risk factors for survival]
    Thomas Eitz
    Klinik für Thorax und Kardiovaskularchirurgie, Herz und Diabeteszentrum Nordrhein Westfalen, Bad Oeynhausen
    Herz 31:699-703. 2006
    ..However, reliable data on mortality and its risk factors in octogenarians after replacement of aortic bioprostheses are limited...
  81. ncbi request reprint The Bad Oeynhausen concept of INR self-management
    Heinrich Koertke
    Department of Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westphalia, Clinic of the Ruhr University Bochum, Bad Oeynhausen, Germany
    J Thromb Thrombolysis 19:25-31. 2005
    ..The development of portable anticoagulation monitors has enabled self-testing and self-adjustment of anticoagulation therapy...
  82. ncbi request reprint Self-management of oral anticoagulation therapy improves long-term survival in patients with mechanical heart valve replacement
    Heinrich Koertke
    Department of Cardiothoracic Surgery, Heart Center North Rhine Westphalia Bad Oeynhausen, Clinic of the Ruhr University Bochum, Germany
    Ann Thorac Surg 83:24-9. 2007
    ..However, the effects of self-management on long-term survival are currently not known...
  83. doi request reprint No association between single nucleotide polymorphisms and the development of nephrotoxicity after orthotopic heart transplantation
    Bärbel Klauke
    Heart and Diabetescenter NRW, Universitätsklinikum der Ruhr Universität Bochum, Erich and Hanna Klessmann Institut für Kardiovaskuläre Forschung and Entwicklung, Bad Oeynhausen, Germany
    J Heart Lung Transplant 27:741-5. 2008
    ..To determine whether genetic factors are involved in the development of renal dysfunction under immunosuppressive therapy, we screened various genes for sequence variations...
  84. ncbi request reprint Organs from donors with primary brain malignancy: the fate of cardiac allograft recipients
    L Hornik
    Department of Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westphalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    Transplant Proc 36:3133-7. 2004
    ..The phenomenon of malignancy transmission from donors with primary brain malignancy (PBM) which is relatively well documented in renal or liver transplant recipients, has not been analyzed in cardiac allograft recipients...
  85. doi request reprint [Postoperative assessment of daily energy expenditure. Comparison of two methods]
    R Dummler
    Institut für Anästhesiologie und Intensivmedizin, Krankenhaus Bad Oeynhausen, Wielandstr 28, 32545 Bad Oeynhausen, Germany
    Anaesthesist 62:20-6. 2013
    ..Furthermore, postsurgical pain therapy by continuous thoracic epidural anaesthesia (t-PDA) was compared with continuous intravenous pain therapy regarding EESWA in these patients...
  86. ncbi request reprint Heparin-coated extracorporeal circulation in combination with low dose systemic heparinization reduces early postoperative blood loss in cardiac surgery
    N Mirow
    Department of Thoracic and Cardiovascular Surgery, Heart Center NRW, Ruhr University of Bochum, Bad Oeynhausen, Germany
    J Cardiovasc Surg (Torino) 49:277-84. 2008
    ..We investigated the effects of heparin-coated circuits in combination with a reduced systemic heparin dose on early postoperative blood loss (first 12 h), platelet function, and postoperative complications...
  87. ncbi request reprint Oral contraceptives moderately effect bone resorption markers and serum-soluble interleukin-6 receptor concentrations
    A Zittermann
    Department of Nutrition Science, University of Bonn, Endenicher Allee 11 13, 53115 Bonn, Germany
    Calcif Tissue Int 70:11-21. 2002
    ..Results are a further indication that monthly fluctuations of bone resorption in young women are mediated by sex hormones and that osteoclastic activity is stimulated by cytokines in vivo...
  88. ncbi request reprint Long-term survival after cardiac retransplantation: a single-center experience
    Masataka Yoda
    Department of Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westphalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    Int Heart J 49:213-20. 2008
    ..6/68.4%, respectively. Long-term survival after retransplantation was acceptable for patients with CAV and PGF, however, we should select patients carefully if the indication for retransplantation is IACR because of the poor outcome...
  89. ncbi request reprint Heart transplantation in insulin-treated diabetic mellitus patients with diabetes-related complications
    Yoshifumi Ikeda
    Department of Cardio Thoracic Surgery, Heart Center North Rhine Westfalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    Transpl Int 20:528-33. 2007
    ..Our data demonstrate that long-term survival is acceptable in heart transplant recipients with preoperatively diagnosed DM and DRCs. Consequently, advanced DM should no longer be a relative contraindication for heart transplantation...
  90. ncbi request reprint Safety of low-dose aprotinin in coronary artery bypass graft surgery: a single-centre investigation in 2,436 patients in Germany
    Mario Kluth
    Institute for Anaesthesiology, Heart Center North Rhine Westfalia, Ruhr University Bochum, Bad Oeynhausen, Germany
    Drug Saf 31:617-26. 2008
    ..In a recently performed multicentre observational study, the use of aprotinin was dose-dependently associated with a higher risk of renal failure and cardiovascular events...
  91. ncbi request reprint Cytomegalovirus-induced pancytopenia after heart transplantation
    Uwe Fuchs
    Transplantation 78:783-4. 2004
  92. ncbi request reprint Beyond deficiency: potential benefits of increased intakes of vitamin K for bone and vascular health
    Cees Vermeer
    Dept of Biochemistry, University of Maastricht, P O Box 616, 6200 MD Maastricht, The Netherlands
    Eur J Nutr 43:325-35. 2004
    ....
  93. ncbi request reprint Age-dependent effects of atorvastatin on biochemical bone turnover markers: a randomized controlled trial in postmenopausal women
    Heiner K Berthold
    Institute for Clinical Research and Department Clinical Pharmacology, Center for Cardiovascular Diseases, Rotenburg an der Fulda, Germany
    Osteoporos Int 15:459-67. 2004
    ..gt;63 years). In summary, the present data suggest that short-term treatment with atorvastatin may have age-dependent effects on biochemical markers of bone turnover in postmenopausal women...
  94. ncbi request reprint Letter by Zitterman et al regarding article, "Calcium/vitamin D supplementation and cardiovascular events"
    Armin Zittermann
    Circulation 116:e85; author reply e87. 2007
  95. ncbi request reprint Serum 25-hydroxyvitamin D response to oral vitamin D intake in children
    Armin Zittermann
    Am J Clin Nutr 78:496-7. 2003
  96. doi request reprint Everolimus exposure in cardiac transplant recipients is influenced by concomitant calcineurin inhibitor
    Gunnar Brandhorst
    Department of Clinical Chemistry, University Hospital Goettingen, Goettingen, Germany
    Ther Drug Monit 30:113-6. 2008
    ..Our results confirm this interaction under clinical conditions and suggest close drug monitoring when converting the calcineurin inhibitor under concomitant mammalian target of rapamycin-inhibitor therapy...
  97. ncbi request reprint The urgent need to recommend an intake of vitamin D that is effective
    Reinhold Vieth
    Am J Clin Nutr 85:649-50. 2007
  98. ncbi request reprint Is there a role of the Thr164Ile-beta(2)-adrenoceptor polymorphism for the outcome of chronic heart failure?
    Kirsten Leineweber
    Department of Pathophysiology, University of Essen School of Medicine, Hufelandstr 55, 45147 Essen, Germany
    Basic Res Cardiol 101:479-84. 2006
    ..This study aimed to further evaluate the role of the Thr164Ile-beta(2)AR in CHF. For this we hypothesized that the Thr164Ile-beta(2)AR variant should be more abundant in HTX-patients than in patients with stable CHF or healthy controls...