Ingo H Tarner

Summary

Affiliation: Bad Nauheim
Country: Germany

Publications

  1. pmc Natural killer cells trigger differentiation of monocytes into dendritic cells
    Angela L Zhang
    Department of Pathology, Stanford University School of Medicine, Palo Alto, CA 94304 1204, USA
    Blood 110:2484-93. 2007
  2. pmc Treatment of active lupus nephritis with the novel immunosuppressant 15-deoxyspergualin: an open-label dose escalation study
    Hanns Martin Lorenz
    Division of Rheumatology, University Hospital Heidelberg, INF410, 69120 Heidelberg, Germany
    Arthritis Res Ther 13:R36. 2011
  3. ncbi request reprint Developing the concept of adoptive cellular gene therapy of rheumatoid arthritis
    Ingo H Tarner
    University Hospital Giessen, Department of Internal Medicine and Rheumatology, Division of Rheumatology and Clinical Immunology, Kerckhoff Klinik, Bad Nauheim, Germany
    Autoimmun Rev 5:148-52. 2006
  4. pmc Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts
    Elena Neumann
    Department of Internal Medicine and Rheumatology, University of Giessben, Kerckhoff Klinik, D 61231 Bad Nauheim, Benekestr, 2 8, Germany
    Arthritis Res Ther 12:R83. 2010
  5. pmc Synovial fibroblasts spread rheumatoid arthritis to unaffected joints
    Stephanie Lefèvre
    Department of Internal Medicine and Rheumatology, Justus Liebig University Giessen, Kerckhoff Clinic, Bad Nauheim, Germany
    Nat Med 15:1414-20. 2009
  6. ncbi request reprint Emerging targets of biologic therapies for rheumatoid arthritis
    Ingo H Tarner
    Department of Internal Medicine and Rheumatology, Justus Liebig University of Giessen, and Division of Rheumatology and Clinical Immunology at the Kerckhoff Klinik Bad Nauheim, Germany
    Nat Clin Pract Rheumatol 3:336-45. 2007
  7. ncbi request reprint High-resolution molecular analysis for research in rheumatology
    Atsushi Hashimoto
    Department of Rheumatology and Clinical Immunology, University of Giessen, Kerckhoff Klinik Bad Nauheim, Benekestrasse 2 8, 61231 Bad Nauheim, Germany
    Curr Rheumatol Rep 8:1-2. 2006
  8. ncbi request reprint Drug delivery systems for the treatment of rheumatoid arthritis
    Ingo H Tarner
    Department of Internal Medicine and Rheumatology, Division of Rheumatology and Clinical Immunology, Justus Liebig University of Giessen, D 61231 Bad Nauheim, Germany
    Expert Opin Drug Deliv 5:1027-37. 2008
  9. doi request reprint [A wolf in sheep's clothing: atypical systemic lupus erythematosus (SLE) presenting as cardiovascular disease]
    Ingo H Tarner
    Lehrstuhl für Innere Medizin mit Schwerpunkt Rheumatologie, Justus Liebig Universitat Giessen, Abteilung für Rheumatologie, Klinische Immunologie, Osteologie und physikalische Medizin, Kerckhoff Klinik, Bad Nauheim, Germany
    Med Klin (Munich) 105:300-4. 2010
  10. doi request reprint The effect of mild whole-body hyperthermia on systemic levels of TNF-alpha, IL-1beta, and IL-6 in patients with ankylosing spondylitis
    Ingo H Tarner
    Department of Internal Medicine and Rheumatology, Division of Rheumatology, Clinical Immunology and Physical Medicine, Justus Liebig University of Giessen, Kerckhoff Klinik, 61231 Bad Nauheim, Germany
    Clin Rheumatol 28:397-402. 2009

Collaborators

Detail Information

Publications25

  1. pmc Natural killer cells trigger differentiation of monocytes into dendritic cells
    Angela L Zhang
    Department of Pathology, Stanford University School of Medicine, Palo Alto, CA 94304 1204, USA
    Blood 110:2484-93. 2007
    ..However, this process occurs only in the presence of NK cells. We propose that NK cells play a role in the maintenance of T(H)1-mediated inflammatory diseases such as RA by providing a local milieu for monocytes to differentiate into DC...
  2. pmc Treatment of active lupus nephritis with the novel immunosuppressant 15-deoxyspergualin: an open-label dose escalation study
    Hanns Martin Lorenz
    Division of Rheumatology, University Hospital Heidelberg, INF410, 69120 Heidelberg, Germany
    Arthritis Res Ther 13:R36. 2011
    ....
  3. ncbi request reprint Developing the concept of adoptive cellular gene therapy of rheumatoid arthritis
    Ingo H Tarner
    University Hospital Giessen, Department of Internal Medicine and Rheumatology, Division of Rheumatology and Clinical Immunology, Kerckhoff Klinik, Bad Nauheim, Germany
    Autoimmun Rev 5:148-52. 2006
    ....
  4. pmc Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts
    Elena Neumann
    Department of Internal Medicine and Rheumatology, University of Giessben, Kerckhoff Klinik, D 61231 Bad Nauheim, Benekestr, 2 8, Germany
    Arthritis Res Ther 12:R83. 2010
    ..We evaluated, whether passaging during culture and freezing has effects on gene expression and cell proliferation...
  5. pmc Synovial fibroblasts spread rheumatoid arthritis to unaffected joints
    Stephanie Lefèvre
    Department of Internal Medicine and Rheumatology, Justus Liebig University Giessen, Kerckhoff Clinic, Bad Nauheim, Germany
    Nat Med 15:1414-20. 2009
    ..These findings support the hypothesis that the characteristic clinical phenomenon of destructive arthritis spreading between joints is mediated, at least in part, by the transmigration of activated RASFs...
  6. ncbi request reprint Emerging targets of biologic therapies for rheumatoid arthritis
    Ingo H Tarner
    Department of Internal Medicine and Rheumatology, Justus Liebig University of Giessen, and Division of Rheumatology and Clinical Immunology at the Kerckhoff Klinik Bad Nauheim, Germany
    Nat Clin Pract Rheumatol 3:336-45. 2007
    ....
  7. ncbi request reprint High-resolution molecular analysis for research in rheumatology
    Atsushi Hashimoto
    Department of Rheumatology and Clinical Immunology, University of Giessen, Kerckhoff Klinik Bad Nauheim, Benekestrasse 2 8, 61231 Bad Nauheim, Germany
    Curr Rheumatol Rep 8:1-2. 2006
  8. ncbi request reprint Drug delivery systems for the treatment of rheumatoid arthritis
    Ingo H Tarner
    Department of Internal Medicine and Rheumatology, Division of Rheumatology and Clinical Immunology, Justus Liebig University of Giessen, D 61231 Bad Nauheim, Germany
    Expert Opin Drug Deliv 5:1027-37. 2008
    ..This article, therefore, reviews a selection of studies that report promising strategies for joint specific delivery of antiarthritic drugs...
  9. doi request reprint [A wolf in sheep's clothing: atypical systemic lupus erythematosus (SLE) presenting as cardiovascular disease]
    Ingo H Tarner
    Lehrstuhl für Innere Medizin mit Schwerpunkt Rheumatologie, Justus Liebig Universitat Giessen, Abteilung für Rheumatologie, Klinische Immunologie, Osteologie und physikalische Medizin, Kerckhoff Klinik, Bad Nauheim, Germany
    Med Klin (Munich) 105:300-4. 2010
    ..Its atypical presentation impeded a timely diagnosis of SLE significantly, however, in retrospect the correct diagnosis would have been possible at an earlier time point...
  10. doi request reprint The effect of mild whole-body hyperthermia on systemic levels of TNF-alpha, IL-1beta, and IL-6 in patients with ankylosing spondylitis
    Ingo H Tarner
    Department of Internal Medicine and Rheumatology, Division of Rheumatology, Clinical Immunology and Physical Medicine, Justus Liebig University of Giessen, Kerckhoff Klinik, 61231 Bad Nauheim, Germany
    Clin Rheumatol 28:397-402. 2009
    ..In AS patients, hyperthermia caused a significant reduction of all cytokines by 40-50%. Thus, serial mild whole-body hyperthermia in AS results in heat-induced changes of the proinflammatory cytokine network...
  11. doi request reprint The role of corticosteroids for pain relief in persistent pain of inflammatory arthritis: a systematic literature review
    Ingo H Tarner
    Department of Internal Medicine and Rheumatology, Justus Liebig University Giessen, Department of Rheumatology, Clinical Immunology, Osteology and Physical Medicine Kerckhoff Klinik, Benekestrasse 2 8, D 61231 Bad Nauheim, Germany
    J Rheumatol Suppl 90:17-20. 2012
    ....
  12. ncbi request reprint Does our current understanding of the molecular basis of immune tolerance predict new therapies for autoimmune disease?
    Ingo H Tarner
    Department of Internal Medicine and Rheumatology, Justus Liebig University of Giessen, Kerckhoff Klinik Bad Nauheim, Division of Rheumatology and Clinical Immunology, Bad Nauheim, Germany
    Nat Clin Pract Rheumatol 2:491-9. 2006
    ..These landmarks of immune-tolerance research are summarized and their potential use in the immunotherapy of autoimmune disease discussed...
  13. ncbi request reprint Analysis of vascular gene expression in arthritic synovium by laser-mediated microdissection
    Atsushi Hashimoto
    Department of Medicine and Rheumatology, Justus Liebig University of Giessen, Giessen, and University Hospital Regensburg, Germany
    Arthritis Rheum 56:1094-105. 2007
    ..The aim of this study was to analyze the specific synovial vascular expression profiles of several angiogenesis-related genes as well as CD82 in RA compared with osteoarthritis (OA), using laser-mediated microdissection (LMM)...
  14. ncbi request reprint Local production of complement proteins in rheumatoid arthritis synovium
    Elena Neumann
    University of Regensburg, Regensburg, Germany
    Arthritis Rheum 46:934-45. 2002
    ..This study was undertaken to characterize the expression of complement proteins and receptors in RA SF and ST...
  15. ncbi request reprint Retroviral gene therapy of collagen-induced arthritis by local delivery of IL-4
    Ingo H Tarner
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University, School of Medicine, Stanford, California 94305, USA
    Clin Immunol 105:304-14. 2002
    ....
  16. ncbi request reprint Adoptive cellular gene therapy of autoimmune disease
    Anthony J Slavin
    Stanford University School of Medicine, Department of Medicine, Division of Immunology and Rheumatology, Stanford University, Stanford University Medical Center, 300 Pasteur Dve, CCSR 2225, Stanford, CA 94305, USA
    Autoimmun Rev 1:213-9. 2002
    ....
  17. ncbi request reprint Evaluation of differentially expressed genes by a combination of cDNA array and RAP-PCR using the AtlasImage 2.0 software
    Elena Neumann
    Department of Internal Medicine I, University Hospital Regensburg, D 93042, Regensburg, Germany
    J Autoimmun 21:161-6. 2003
    ..To compare RA vs. OA synovial fibroblasts and normal vs. CA expression patterns, global normalization using the sum method is recommended...
  18. ncbi request reprint Treatment of autoimmune disease by adoptive cellular gene therapy
    Ingo H Tarner
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, California 94305, USA
    Ann N Y Acad Sci 998:512-9. 2003
    ....
  19. ncbi request reprint The different stages of synovitis: acute vs chronic, early vs late and non-erosive vs erosive
    Ingo H Tarner
    Department of Internal Medicine I, University Hospital Regensburg, D 93042 Regensburg, Germany
    Best Pract Res Clin Rheumatol 19:19-35. 2005
    ..This chapter will therefore describe the physiological structure of the synovium and the inflammatory pathology of rheumatoid synovitis in early and chronic stages of the disease...
  20. ncbi request reprint Targeted gene therapy: frontiers in the development of 'smart drugs'
    Ingo H Tarner
    Department of Internal Medicine I, University Hospital Regensburg, D 93042 Regensburg, Germany
    Trends Biotechnol 22:304-10. 2004
    ..Special attention is given to advances in, and limitations of, controlled and targeted gene product application in inflammatory diseases...
  21. doi request reprint An early sympathetic nervous system influence exacerbates collagen-induced arthritis via CD4+CD25+ cells
    Peter Härle
    University Hospital Regensburg, Regensburg, Germany
    Arthritis Rheum 58:2347-55. 2008
    ..The aim of the present study was to determine whether CD4+CD25+ T cells are influenced by the SNS of mice and play a disease-modifying role in the early symptomatic phase of the disease...
  22. ncbi request reprint Severe fibrosis and increased expression of fibrogenic cytokines in the gastric wall of systemic sclerosis patients
    Mirko Manetti
    University of Florence, Florence, Italy
    Arthritis Rheum 56:3442-7. 2007
    ..The present study was undertaken to evaluate the fibrotic process and the expression of fibrogenic cytokines in the gastric wall of SSc patients with gastroesophageal involvement...
  23. ncbi request reprint The potential of adiponectin in driving arthritis
    Angela Ehling
    Department of Internal Medicine I, University Hospital Regensburg, Germany
    J Immunol 176:4468-78. 2006
    ..In summary, articular adipose tissue and adipocytokines cannot be regarded as innocent bystanders any more in chronic inflammatory diseases such as arthritis...
  24. ncbi request reprint The potential for gene therapy in the treatment of autoimmune disease
    Ingo H Tarner
    Department of Rheumatology, Stanford University School of Medicine, California 94305 5166, USA
    Clin Immunol 104:204-16. 2002
  25. ncbi request reprint Analysis of gene expression patterns in systemic sclerosis fibroblasts using RNA arbitrarily primed-polymerase chain reaction for differential display
    Rotraud Meyringer
    From the Department of Internal Medicine I, University of Regensburg
    J Rheumatol 34:747-53. 2007
    ....