Klaus Frommer

Summary

Affiliation: Department of Internal Medicine and Rheumatology, Justus Liebig University Giessen, Kerckhoff-Klinik Bad Nauheim
Location: Bad Nauheim, Germany

Publications

  1. ncbi request reprint IGF-independent effects of IGFBP-2 on the human breast cancer cell line Hs578T
    Klaus W Frommer
    Pediatric Endocrinology Section, University Children s Hospital, 72076 Tuebingen, Germany
    J Mol Endocrinol 37:13-23. 2006
  2. pmc Visfatin/pre-B-cell colony-enhancing factor (PBEF), a proinflammatory and cell motility-changing factor in rheumatoid arthritis
    Florian M P Meier
    Department of Internal Medicine and Rheumatology, Justus Liebig University Giessen, and the Kerckhoff Klinik, D 61231 Bad Nauheim, Germany
    J Biol Chem 287:28378-85. 2012
  3. doi request reprint Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database
    Florian M P Meier
    Department of Internal Medicine and Rheumatology, Justus Liebig University Gießen Kerckhoff Klinik, Bad Nauheim, Germany
    Ann Rheum Dis 71:1355-60. 2012
  4. doi request reprint Adiponectin isoforms: a potential therapeutic target in rheumatoid arthritis?
    Klaus W Frommer
    Department of Internal Medicine and Rheumatology Justus Liebig University Giessen Kerckhoff Klinik Benekestrasse 2 8 D 61231 Bad Nauheim, Germany
    Ann Rheum Dis 71:1724-32. 2012
  5. doi request reprint Chemerin induces CCL2 and TLR4 in synovial fibroblasts of patients with rheumatoid arthritis and osteoarthritis
    Kristina Eisinger
    Department of Internal Medicine I, Regensburg University Hospital, D 93042 Regensburg, Germany
    Exp Mol Pathol 92:90-6. 2012
  6. doi request reprint Adiponectin-mediated changes in effector cells involved in the pathophysiology of rheumatoid arthritis
    Klaus W Frommer
    Justus Liebig University Giessen and Kerckhoff Klinik, Bad Nauheim, Germany
    Arthritis Rheum 62:2886-99. 2010
  7. doi request reprint Immune response of human propagated gammadelta-T-cells to neuroblastoma recommend the Vdelta1+ subset for gammadelta-T-cell-based immunotherapy
    Karin Schilbach
    Department of Pediatric Stem Cell Transplantation, University Children s Hospital, University of Tubingen, Tubingen, Germany
    J Immunother 31:896-905. 2008
  8. doi request reprint Expression and function of ETA and ETB receptors in SSc
    K W Frommer
    Department of Internal Medicine and Rheumatology, Justus Liebig University Giessen, Kerckhoff Klinik Bad Nauheim, Bad Nauheim, Germany
    Rheumatology (Oxford) 47:v27-8. 2008
  9. ncbi request reprint Insulin-like growth factors and binding proteins in early milk from mothers of preterm and term infants
    Martin W Elmlinger
    Pediatric Endocrinology Section, University Children s Hospital, Tubingen, Germany
    Horm Res 68:124-31. 2007
  10. doi request reprint [Intracellular signaling transduction pathways. Potential targets in the treatment of rheumatic diseases]
    K W Frommer
    Innere Medizin mit Schwerpunkt Rheumatologie, Kerckhoff Klinik, Abt Rheumatologie und Klin Immunologie, Franz Groedel Institut, Justus Liebig Universität Gießen, Benekestr 2 8, 61231, Bad Nauheim, Deutschland
    Z Rheumatol 71:460-7. 2012

Collaborators

Detail Information

Publications10

  1. ncbi request reprint IGF-independent effects of IGFBP-2 on the human breast cancer cell line Hs578T
    Klaus W Frommer
    Pediatric Endocrinology Section, University Children s Hospital, 72076 Tuebingen, Germany
    J Mol Endocrinol 37:13-23. 2006
    ..Our results suggest that IGFBP-2-induced gene expressions are of functional significance for proliferation, cell adhesion, cell migration and apoptosis, and showed that IGFBP-2 can promote apoptosis in tumor cells independent of IGF...
  2. pmc Visfatin/pre-B-cell colony-enhancing factor (PBEF), a proinflammatory and cell motility-changing factor in rheumatoid arthritis
    Florian M P Meier
    Department of Internal Medicine and Rheumatology, Justus Liebig University Giessen, and the Kerckhoff Klinik, D 61231 Bad Nauheim, Germany
    J Biol Chem 287:28378-85. 2012
    ..The results of this study indicate that visfatin/PBEF is involved in synovial fibroblast activation by triggering fibroblast motility and promoting cytokine synthesis at central sites in RA synovium...
  3. doi request reprint Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database
    Florian M P Meier
    Department of Internal Medicine and Rheumatology, Justus Liebig University Gießen Kerckhoff Klinik, Bad Nauheim, Germany
    Ann Rheum Dis 71:1355-60. 2012
    ..Systemic sclerosis (SSc) is a rare disease requiring multicentre collaboration to reveal comprehensive details of disease-related causes for morbidity and mortality...
  4. doi request reprint Adiponectin isoforms: a potential therapeutic target in rheumatoid arthritis?
    Klaus W Frommer
    Department of Internal Medicine and Rheumatology Justus Liebig University Giessen Kerckhoff Klinik Benekestrasse 2 8 D 61231 Bad Nauheim, Germany
    Ann Rheum Dis 71:1724-32. 2012
    ....
  5. doi request reprint Chemerin induces CCL2 and TLR4 in synovial fibroblasts of patients with rheumatoid arthritis and osteoarthritis
    Kristina Eisinger
    Department of Internal Medicine I, Regensburg University Hospital, D 93042 Regensburg, Germany
    Exp Mol Pathol 92:90-6. 2012
    ..Here, we analyzed whether synovial fibroblasts express chemerin and its receptor CMKLR1. Further, the role of chemerin in synovial fibroblast chemotaxis, proliferation, insulin response and release of inflammatory proteins was studied...
  6. doi request reprint Adiponectin-mediated changes in effector cells involved in the pathophysiology of rheumatoid arthritis
    Klaus W Frommer
    Justus Liebig University Giessen and Kerckhoff Klinik, Bad Nauheim, Germany
    Arthritis Rheum 62:2886-99. 2010
    ....
  7. doi request reprint Immune response of human propagated gammadelta-T-cells to neuroblastoma recommend the Vdelta1+ subset for gammadelta-T-cell-based immunotherapy
    Karin Schilbach
    Department of Pediatric Stem Cell Transplantation, University Children s Hospital, University of Tubingen, Tubingen, Germany
    J Immunother 31:896-905. 2008
    ..Furthermore, in contrast to other cell types, Vdelta1+ T cells do not sustain a growth-promoting or tolerogenic microenvironment. These data make Vdelta1+ T cells an ideal candidate for upcoming immunotherapy trials in Nb...
  8. doi request reprint Expression and function of ETA and ETB receptors in SSc
    K W Frommer
    Department of Internal Medicine and Rheumatology, Justus Liebig University Giessen, Kerckhoff Klinik Bad Nauheim, Bad Nauheim, Germany
    Rheumatology (Oxford) 47:v27-8. 2008
    ....
  9. ncbi request reprint Insulin-like growth factors and binding proteins in early milk from mothers of preterm and term infants
    Martin W Elmlinger
    Pediatric Endocrinology Section, University Children s Hospital, Tubingen, Germany
    Horm Res 68:124-31. 2007
    ..The results provide further evidence that IGFBP-2 and IGF-II in breast milk are relevant factors for the early development of preterm infants...
  10. doi request reprint [Intracellular signaling transduction pathways. Potential targets in the treatment of rheumatic diseases]
    K W Frommer
    Innere Medizin mit Schwerpunkt Rheumatologie, Kerckhoff Klinik, Abt Rheumatologie und Klin Immunologie, Franz Groedel Institut, Justus Liebig Universität Gießen, Benekestr 2 8, 61231, Bad Nauheim, Deutschland
    Z Rheumatol 71:460-7. 2012
    ..The English full-text version of this article is available at SpringerLink (under "Supplemental")...