Affiliation: Bad Oeynhausen
Faust I, Weile J, Fujita B, Kandolf R, Hendig D, Vollmer T, et al
. Heart Transplantation in Systemic Sclerosis: New Impulses for Conventional Scleroderma Transplantation Regimen and Scleroderma Diagnostic Monitoring: 2 Case Reports. Transplant Proc. 2019;51:865-870 pubmed publisher
Riedel L, Fischer B, Ly T, Hendig D, Kuhn J, Knabbe C, et al
. microRNA-29b mediates fibrotic induction of human xylosyltransferase-I in human dermal fibroblasts via the Sp1 pathway. Sci Rep. 2018;8:17779 pubmed publisher
..Our observations will facilitate the understanding of complex molecular fibrotic pathways and provide new opportunities to investigate microRNA-based antifibrotic tools. ..
Faust I, BÃ¶ker K, Eirich C, Akkermann D, Kuhn J, Knabbe C, et al
. Identification and characterization of human xylosyltransferase II promoter single nucleotide variants. Biochem Biophys Res Commun. 2015;458:901-7 pubmed publisher
Faust I, Donhauser E, Fischer B, Ibold B, Kuhn J, Knabbe C, et al
. Characterization of dermal myofibroblast differentiation in pseudoxanthoma elasticum. Exp Cell Res. 2017;360:153-162 pubmed publisher
..These results not only improve our insights into cellular PXE pathophysiology, but might also qualify us to interfere with ECM remodeling in the future. ..
Faust I, BÃ¶ker K, Lichtenberg C, Kuhn J, Knabbe C, Hendig D. First description of the complete human xylosyltransferase-I promoter region. BMC Genet. 2014;15:129 pubmed publisher
..Future studies should analyze the impact of regulatory XYLT1 promoter variations on XT-associated diseases. ..