A Agaimy

Summary

Country: Germany

Publications

  1. ncbi Primary and metastatic high-grade pleomorphic sarcoma/malignant fibrous histiocytoma of the gastrointestinal tract: an approach to the differential diagnosis in a series of five cases with emphasis on myofibroblastic differentiation
    Abbas Agaimy
    Institute of Pathology, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nurnberg, Germany
    Virchows Arch 451:949-57. 2007
  2. ncbi Microscopic gastrointestinal stromal tumors in esophageal and intestinal surgical resection specimens: a clinicopathologic, immunohistochemical, and molecular study of 19 lesions
    Abbas Agaimy
    Institute of Pathology, Nürnberg Clinic Center, Nurnberg, Germany
    Am J Surg Pathol 32:867-73. 2008
  3. ncbi Multiple sporadic gastrointestinal stromal tumors (GISTs) of the proximal stomach are caused by different somatic KIT mutations suggesting a field effect
    Abbas Agaimy
    Institute of Pathology, Nürnberg Clinic Center, Nurnberg, Germany daggerInstitute of Pathology, University of Basel, Basel, Switzerland
    Am J Surg Pathol 32:1553-9. 2008
  4. ncbi Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: a report of three new cases with mutational analysis and comparative genomic hybridization
    Abbas Agaimy
    Institute of Pathology, Klinikum Nürnberg, 90419 Nurnberg, Germany
    Oncol Rep 18:9-15. 2007
  5. ncbi Minute gastric sclerosing stromal tumors (GIST tumorlets) are common in adults and frequently show c-KIT mutations
    Abbas Agaimy
    Institute of Pathology, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nuremberg, Germany
    Am J Surg Pathol 31:113-20. 2007
  6. ncbi Occurrence of other malignancies in patients with gastrointestinal stromal tumors
    Abbas Agaimy
    Institute of Pathology, Nuremberg Clinic Center, Nuremberg, Germany
    Semin Diagn Pathol 23:120-9. 2006
  7. ncbi True smooth muscle neoplasms of the gastrointestinal tract: morphological spectrum and classification in a series of 85 cases from a single institute
    Abbas Agaimy
    Institut fur Pathologie, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nurnberg, Germany
    Langenbecks Arch Surg 392:75-81. 2007
  8. ncbi Epithelioid and sarcomatoid malignant pleural mesothelioma in endoscopic gastric biopsies: a diagnostic pitfall
    Abbas Agaimy
    Institut fur Pathologie, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nurnberg, Germany
    Pathol Res Pract 202:617-22. 2006
  9. ncbi Gastrointestinal stromal tumors of the vermiform appendix: clinicopathologic, immunohistochemical, and molecular study of 2 cases with literature review
    Abbas Agaimy
    Institute of Pathology, Klinikum Nürnberg, 90419 Nurnberg, Germany
    Hum Pathol 39:1252-7. 2008
  10. ncbi Follicular dendritic cell tumor of the gastrointestinal tract: Report of a rare neoplasm and literature review
    Abbas Agaimy
    Institut fur Pathologie, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nurnberg, Germany
    Pathol Res Pract 202:541-8. 2006

Detail Information

Publications32

  1. ncbi Primary and metastatic high-grade pleomorphic sarcoma/malignant fibrous histiocytoma of the gastrointestinal tract: an approach to the differential diagnosis in a series of five cases with emphasis on myofibroblastic differentiation
    Abbas Agaimy
    Institute of Pathology, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nurnberg, Germany
    Virchows Arch 451:949-57. 2007
    ..They should be distinguished from a variety of primary and metastatic pleomorphic neoplasms, in particular high-grade sarcomatous GI stromal tumours (GIST), pleomorphic leiomyosarcoma, sarcomatoid carcinoma and other mimics...
  2. ncbi Microscopic gastrointestinal stromal tumors in esophageal and intestinal surgical resection specimens: a clinicopathologic, immunohistochemical, and molecular study of 19 lesions
    Abbas Agaimy
    Institute of Pathology, Nürnberg Clinic Center, Nurnberg, Germany
    Am J Surg Pathol 32:867-73. 2008
    ..The remarkable variation in the incidence of microscopic GISTs at different GI sites suggests an origin from heterogeneous subsets of interstitial cells of Cajal with varying potentials for neoplastic transformation...
  3. ncbi Multiple sporadic gastrointestinal stromal tumors (GISTs) of the proximal stomach are caused by different somatic KIT mutations suggesting a field effect
    Abbas Agaimy
    Institute of Pathology, Nürnberg Clinic Center, Nurnberg, Germany daggerInstitute of Pathology, University of Basel, Basel, Switzerland
    Am J Surg Pathol 32:1553-9. 2008
    ....
  4. ncbi Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: a report of three new cases with mutational analysis and comparative genomic hybridization
    Abbas Agaimy
    Institute of Pathology, Klinikum Nürnberg, 90419 Nurnberg, Germany
    Oncol Rep 18:9-15. 2007
    ....
  5. ncbi Minute gastric sclerosing stromal tumors (GIST tumorlets) are common in adults and frequently show c-KIT mutations
    Abbas Agaimy
    Institute of Pathology, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nuremberg, Germany
    Am J Surg Pathol 31:113-20. 2007
    ..GIST tumorlets likely represent preclinical (preneoplastic) lesions that need additional stimuli to evolve into clinical GISTs, raising the possibility of a hyperplasia-neoplasia sequence in the development of sporadic GISTs...
  6. ncbi Occurrence of other malignancies in patients with gastrointestinal stromal tumors
    Abbas Agaimy
    Institute of Pathology, Nuremberg Clinic Center, Nuremberg, Germany
    Semin Diagn Pathol 23:120-9. 2006
    ..The potential nonrandom association and causal relationship between GIST and other neoplasms remain to be investigated...
  7. ncbi True smooth muscle neoplasms of the gastrointestinal tract: morphological spectrum and classification in a series of 85 cases from a single institute
    Abbas Agaimy
    Institut fur Pathologie, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nurnberg, Germany
    Langenbecks Arch Surg 392:75-81. 2007
    ..True smooth-muscle neoplasms of the GI tract have been only rarely studied in the KIT era. Their incidence among other GI mesenchymal tumours and their clinicopathological spectrum have not been sufficiently analysed...
  8. ncbi Epithelioid and sarcomatoid malignant pleural mesothelioma in endoscopic gastric biopsies: a diagnostic pitfall
    Abbas Agaimy
    Institut fur Pathologie, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nurnberg, Germany
    Pathol Res Pract 202:617-22. 2006
    ..The major differential diagnoses encompass primary or metastatic adenocarcinoma in case one and cytokeratin-positive (KIT negative!) GI stromal tumors (GISTs) and sarcomatoid carcinoma in case two, as well as other rare entities...
  9. ncbi Gastrointestinal stromal tumors of the vermiform appendix: clinicopathologic, immunohistochemical, and molecular study of 2 cases with literature review
    Abbas Agaimy
    Institute of Pathology, Klinikum Nürnberg, 90419 Nurnberg, Germany
    Hum Pathol 39:1252-7. 2008
    ....
  10. ncbi Follicular dendritic cell tumor of the gastrointestinal tract: Report of a rare neoplasm and literature review
    Abbas Agaimy
    Institut fur Pathologie, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nurnberg, Germany
    Pathol Res Pract 202:541-8. 2006
    ....
  11. ncbi Gastrointestinal stromal tumours: a regular origin in the muscularis propria, but an extremely diverse gross presentation. A review of 200 cases to critically re-evaluate the concept of so-called extra-gastrointestinal stromal tumours
    Abbas Agaimy
    Institut fur Pathologie, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419, Nurnberg, Germany
    Langenbecks Arch Surg 391:322-9. 2006
    ..ICCs form a network surrounding the myenteric plexus and between-muscle fibres of the muscularis propria of the tubular GI tract. The cell of origin of so-called extra-gastrointestinal stromal tumours (EGISTs) is not known...
  12. ncbi Perivascular epithelioid cell sarcoma (malignant PEComa) of the ileum
    A Agaimy
    Institut fur Pathologie, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nurnberg, Germany
    Pathol Res Pract 202:37-41. 2006
    ..The differential diagnosis and malignancy criteria of GI PEComas will be discussed...
  13. ncbi Perineurioma of the stomach. A rare spindle cell neoplasm that should be distinguished from gastrointestinal stromal tumor
    Abbas Agaimy
    Institute of Pathology, Clinic Centre Nuremberg, Prof Ernst Nathan Strasse 1, 90419 Nurnberg, Germany
    Pathol Res Pract 201:463-7. 2005
    ..Gastrointestinal perineuriomas might be under-recognized, as our case was initially diagnosed as a benign GIST...
  14. ncbi Gastrointestinal stromal tumours in patients with other-type cancer: a mere coincidence or an etiological association? A study of 97 GIST cases
    A Agaimy
    Institut fur Pathologie, Klinikum Nürnberg, Nurnberg, Germany
    Z Gastroenterol 43:1025-30. 2005
    ....
  15. ncbi Sporadic Cajal cell hyperplasia is common in resection specimens for distal oesophageal carcinoma. A retrospective review of 77 consecutive surgical resection specimens
    Abbas Agaimy
    Institute of Pathology, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, Nurnberg, Germany
    Virchows Arch 448:288-94. 2006
    ..The possible mechanisms leading to the development of these putative precursor lesions will be discussed...
  16. ncbi Low-grade abdominopelvic sarcoma with myofibroblastic features (low-grade myofibroblastic sarcoma): clinicopathological, immunohistochemical, molecular genetic and ultrastructural study of two cases with literature review
    A Agaimy
    Institute of Pathology, Nuremberg Clinic Centre, Nuremberg, Germany
    J Clin Pathol 61:301-6. 2008
    ..Intra-abdominal LGMS are rare with only four unequivocal examples reported so far. Two further cases in females in their 60s and 70s are analysed here...
  17. ncbi Distribution of neural cell adhesion molecule (NCAM/CD56) in gastrointestinal stromal tumours and their intra-abdominal mesenchymal mimics
    A Agaimy
    Institute of Pathology, Klinikum Nürnberg, Nurnberg, Germany
    J Clin Pathol 61:499-503. 2008
    ..The distribution and reactivity pattern of neural cell adhesion molecule (NCAM/CD56) in gastrointestinal stromal tumours (GISTs) and their mesenchymal mimics have not been investigated in the KIT era...
  18. ncbi V600E BRAF mutations are alternative early molecular events in a subset of KIT/PDGFRA wild-type gastrointestinal stromal tumours
    A Agaimy
    Institute of Pathology, Friedrich Alexander University, Erlangen, Germany
    J Clin Pathol 62:613-6. 2009
    ..However, the frequency and distribution of BRAF mutations within the spectrum of GISTs, and whether they might represent secondary events acquired during tumour progression, remain unknown...
  19. ncbi Lymph node metastasis in gastrointestinal stromal tumours (GIST) occurs preferentially in young patients < or = 40 years: an overview based on our case material and the literature
    Abbas Agaimy
    Institut fur Pathologie, Universitatsklinikum Erlangen, Erlangen, Germany
    Langenbecks Arch Surg 394:375-81. 2009
    ..Data on the clinicopathological and biological profiles of gastrointestinal stromal tumours (GISTs) at higher risk for nodal metastasis are lacking...
  20. ncbi Multiple sporadic gastrointestinal stromal tumours arising at different gastrointestinal sites: pattern of involvement of the muscularis propria as a clue to independent primary GISTs
    Abbas Agaimy
    Institute of Pathology, University Hospital, 91054 Erlangen, Germany
    Virchows Arch 455:101-8. 2009
    ....
  21. ncbi Sporadic segmental Interstitial cell of cajal hyperplasia (microscopic GIST) with unusual diffuse longitudinal growth replacing the muscularis propria: differential diagnosis to hereditary GIST syndromes
    Abbas Agaimy
    Institute of Pathology, University Hospital, Erlangen, Germany
    Int J Clin Exp Pathol 3:549-56. 2010
    ..This peculiar diffuse form of sporadic ICC hyperplasia results from somatic c-KIT mutations and must be distinguished from syndromic ICC hyperplasia associated with hereditary GIST syndromes...
  22. ncbi Benign serrated colorectal fibroblastic polyps/intramucosal perineuriomas are true mixed epithelial-stromal polyps (hybrid hyperplastic polyp/mucosal perineurioma) with frequent BRAF mutations
    Abbas Agaimy
    Institute of Pathology, University Hospital, Erlangen Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany
    Am J Surg Pathol 34:1663-71. 2010
    ..The perineurial stromal component might be derived from modified pericryptic fibroblasts as a consequence of a yet poorly understood epithelial-stromal interaction...
  23. ncbi Leiomyoma of the gallbladder: a case report with review of the literature and discussion of the differential diagnosis
    D L Wachter
    Institute of Pathology, Erlangen University Hospital, Erlangen, Germany
    J Clin Pathol 63:177-9. 2010
    ....
  24. ncbi Hyaline globules in paucicellular leiomyomas of the gastrointestinal tract are distinct from skeinoid fibers and represent degenerating smooth muscle cells
    Abbas Agaimy
    Institute of Pathology, University Hospital of Erlangen, Krankenhausstrasse 12, 91054 Erlagen, Germany
    Pathol Res Pract 205:417-22. 2009
    ..Awareness of this finding would prevent misinterpretation as GIST, particularly in small biopsies...
  25. ncbi Calcifying fibrous tumor of the stomach: clinicopathologic and molecular study of seven cases with literature review and reappraisal of histogenesis
    Abbas Agaimy
    Institute of Pathology, University Hospital, Erlangen, Germany
    Am J Surg Pathol 34:271-8. 2010
    ..They differ from soft tissue CFTs by smaller size, older age at presentation and lack of recurrence, and from peritoneal CFTs by equal gender distribution, older age, and absent multifocal occurrence...
  26. ncbi Severe cytological atypia (large cell change) in focal nodular hyperplasia with numerous mallory bodies. A benign (adaptive) change?
    Abbas Agaimy
    Institute of Pathology, Clinical Center of Nuremberg, Germany
    Pathol Res Pract 199:509-11. 2003
    ..This rare variant of FNH should be differentiated from other neoplastic lesions, in particular from the fibrolamellar variant of hepatocellular carcinoma...
  27. ncbi Distinct biphasic histomorphological pattern in gastrointestinal stromal tumours (GISTs) with common primary mutations but divergent molecular cytogenetic progression
    Abbas Agaimy
    Institute of Pathology, Nürnberg Clinic Centre, Nurnberg, Germany
    Histopathology 54:295-302. 2009
    ..The aim of this study was to shed light on the molecular pathogenesis of GISTs displaying a distinct biphasic histomorphological pattern, which is poorly understood...
  28. ncbi Gastrointestinal stromal tumors (GIST) from risk stratification systems to the new TNM proposal: more questions than answers? A review emphasizing the need for a standardized GIST reporting
    Abbas Agaimy
    Institute of Pathology, Friedrich Alexander University Erlangen, 91054 Erlangen, Germany
    Int J Clin Exp Pathol 3:461-71. 2010
    ....
  29. ncbi Unexpected and potentially misleading TTF-1 expression: a word of caution
    Abbas Agaimy
    Virchows Arch 449:603-5. 2006
  30. ncbi Gastrointestinal stromal tumours (GIST) in kidney transplant recipients--a report of two cases
    Abbas Agaimy
    Nephrol Dial Transplant 22:1489-90. 2007
  31. ncbi Intestinal-type adenocarcinoma arising in a congenital sublingual teratoid cyst
    Abbas Agaimy
    Virchows Arch 450:479-81. 2007
  32. ncbi Perivascular epithelioid cell tumor of the liver coexisting with a gastrointestinal stromal tumor
    Carlos Eduardo Paiva
    Oncological and Hemato oncological Center, Sao Paulo State University, Rua Antonio Nunes da Silva Sobrinho, 180 Jardim Paraiso II Botucatu, Sao Paulo 18610 170, Brazil
    World J Gastroenterol 14:800-2. 2008
    ..Hepatic lesions detected synchronously or metachronously in patients with GISTs may represent histogenetically distinct lesions and should be sampled to confirm or exclude metastatic GISTs...