Research Topics
| Jack WatersSummaryAffiliation: Abteilung Zellphysiologie Country: Germany Publications
| Collaborators
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Detail Information
Publications
Stability and plasticity of developing synapses in hippocampal neuronal culturesF Woodward Hopf
Ernest Gallo Clinic and Research Center, Emeryville, California 94608, Abteilung, Germany
J Neurosci 22:775-81. 2002..These observations provide new information on the stability of developing presynaptic function and suggest that NMDA receptor activation may regulate the stability of developing synapses...- Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivoTanjew Dittgen
Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany
Proc Natl Acad Sci U S A 101:18206-11. 2004..This approach is ideally suited for analysis of gene functions in individual neurons in the intact brain... - Backpropagating action potentials in neurones: measurement, mechanisms and potential functionsJack Waters
Abteilung Zellphysiologie, Max Planck Institut fur medizinische Forschung, Jahnstrasse 29, Heidelberg D 69120, Germany
Prog Biophys Mol Biol 87:145-70. 2005.... - Vesicle pool partitioning influences presynaptic diversity and weighting in rat hippocampal synapsesJack Waters
Department of Molecular and Cellular Physiology, Beckman Center, Stanford Medical School, Stanford 94305, USA
J Physiol 541:811-23. 2002..Since hippocampal single unit firing rates shift between 1 Hz and 10 Hz regimes with behavioural state, differential partitioning may be a mechanism for encoding information in hippocampal circuits... - Supralinear Ca2+ influx into dendritic tufts of layer 2/3 neocortical pyramidal neurons in vitro and in vivoJack Waters
Abteilung Zellphysiologie, Max Planck Institut fur medizinische Forschung, 69120 Heidelberg, Germany
J Neurosci 23:8558-67. 2003..This dendritic supralinearity enables layer 2/3 neurons to integrate ascending sensory input from layer 4 and associative input to layer 1... - Mitochondria and release at hippocampal synapsesJack Waters
Department of Molecular and Cellular Physiology, Beckman Center, Stanford Medical School, Stanford, CA 94305, USA
Pflugers Arch 447:363-70. 2003..A comparison of vesicular release in response to stimulation at 1 Hz and at 10 Hz revealed no differences in release properties between synapses with and without mitochondria... - Boosting of action potential backpropagation by neocortical network activity in vivoJack Waters
Abteilung Zellphysiologie, Max Planck Institut fur medizinische Forschung, 69120 Heidelberg, Germany
J Neurosci 24:11127-36. 2004..Hence, somatic feedback to the dendrites becomes stronger with increasing network activity... - Postsynaptic excitability is necessary for strengthening of cortical sensory responses during experience-dependent developmentShoji Komai
Department of Biomedical Optics, Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany
Nat Neurosci 9:1125-33. 2006..We conclude that somatodendritic excitability of the postsynaptic neuron is needed for the regulation of synaptic strength in the developing sensory cortex... - Dendritic spikes in apical dendrites of neocortical layer 2/3 pyramidal neuronsMatthew Evan Larkum
Abteilung Zellphysiologie, Max Planck Institut fur medizinische Forschung, D 69120 Heidelberg, Germany
J Neurosci 27:8999-9008. 2007..We conclude that L2/3 pyramidal neurons can generate dendritic spikes, sharing with L5 pyramidal neurons fundamental properties of dendritic excitability and control by inhibition... - Background synaptic activity is sparse in neocortexJack Waters
Abteilung Zellphysiologie, Max Planck Institut fur medizinische Forschung, 69120 Heidelberg, Germany
J Neurosci 26:8267-77. 2006..These conditions enhance the effectiveness of each synapse at depolarized potentials. Hence, neocortical networks are relatively quiet at rest, and the effect of synaptic background is weaker than previously thought... - Sindbis vector SINrep(nsP2S726): a tool for rapid heterologous expression with attenuated cytotoxicity in neuronsJinhyun Kim
Max-Planck Institute for Medical Research, Department of Molecular Neurobiology, Jahnstrasse 29, 69120 Heidelberg, Germany
J Neurosci Methods 133:81-90. 2004..As an experimental example, we demonstrate the applicability of this system for high-resolution two-photon imaging of dendritic spines in vivo... - Functional fluorescent Ca2+ indicator proteins in transgenic mice under TET controlMazahir T Hasan
Max Planck Institute for Medical Research, Heidelberg, Germany
PLoS Biol 2:e163. 2004.... - Ca2+ imaging in the mammalian brain in vivoFritjof Helmchen
Abteilung Zellphysiologie, Max Planck Insitut für medizinische Forschung, Jahnstr 29, 69120 Heidelberg, Germany
Eur J Pharmacol 447:119-29. 2002.... - Wilder Penfield in the age of YouTube: visualizing the sequential activation of sensorimotor areas across neocortexDavid Kleinfeld
Department of Physics, University of California at San Diego, La Jolla, CA 92093, USA
Neuron 56:760-2. 2007..imaging activity across the cortical mantle in awake mice, show in this issue of Neuron that touch by a single vibrissa leads to a rapid depolarization of primary sensory and motor areas that subsequently spreads across most of cortex... - Back to basals: do basal dendrites link plateau potentials and Up states?Jack Waters
Feinberg School of Medicine, North-western University, 303 E Chicago Ave, Chicago, IL 60611, USA
J Physiol 585:317. 2007