Michael Koenen

Summary

Affiliation: Abteilung Zellphysiologie
Country: Germany

Publications

  1. pmc Acetylcholine receptor channel subtype directs the innervation pattern of skeletal muscle
    Michael Koenen
    Abteilung Zellphysiologie, Max Planck Institut fur medizinische Forschung, Jahnstrasse 29, 69120 Heidelberg, Germany
    EMBO Rep 6:570-6. 2005
  2. doi request reprint Biophysical characterization of KCNQ1 P320 mutations linked to long QT syndrome 1
    Dierk Thomas
    Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D 69120 Heidelberg, Germany
    J Mol Cell Cardiol 48:230-7. 2010
  3. pmc Transcription profiling of HCN-channel isotypes throughout mouse cardiac development
    Patrick A Schweizer
    Universitatsklinikum Heidelberg, Innere Medizin III, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Basic Res Cardiol 104:621-9. 2009
  4. ncbi request reprint Modification of choline acetyltransferase by integration of green fluorescent protein does not affect enzyme activity and subcellular distribution
    Jan Rathenberg
    Abteilung Zellphysiologie, Max Planck Institut fur medizinische Forschung, Jahnstrasse 29, 69120 Heidelberg, Germany
    Cell Tissue Res 308:1-6. 2002
  5. ncbi request reprint Skipping of Exon 1 in the KCNQ1 gene causes Jervell and Lange-Nielsen syndrome
    Joerg Zehelein
    Universitatsklinikum Heidelberg, Innere Medizin III, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    J Biol Chem 281:35397-403. 2006
  6. ncbi request reprint Cardiac-specific activation of Cre expression at late fetal development
    Jan P Opherk
    Max Planck Institut fur medizinische Forschung, Abteilung Zellphysiologie, Heidelberg, Germany
    Biochem Biophys Res Commun 359:209-13. 2007
  7. ncbi request reprint Atrial-radiofrequency catheter ablation mediated targeting of mesenchymal stromal cells
    Patrick A Schweizer
    Innere Medizin III, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Stem Cells 25:1546-51. 2007
  8. ncbi request reprint Dominant-negative I(Ks) suppression by KCNQ1-deltaF339 potassium channels linked to Romano-Ward syndrome
    Dierk Thomas
    Universitätsklinik Heidelberg, Innere Medizin III, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Cardiovasc Res 67:487-97. 2005

Collaborators

Detail Information

Publications8

  1. pmc Acetylcholine receptor channel subtype directs the innervation pattern of skeletal muscle
    Michael Koenen
    Abteilung Zellphysiologie, Max Planck Institut fur medizinische Forschung, Jahnstrasse 29, 69120 Heidelberg, Germany
    EMBO Rep 6:570-6. 2005
    ..We suggest that one function of the fetal type of AChR is to ensure an orderly innervation pattern of skeletal muscle...
  2. doi request reprint Biophysical characterization of KCNQ1 P320 mutations linked to long QT syndrome 1
    Dierk Thomas
    Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D 69120 Heidelberg, Germany
    J Mol Cell Cardiol 48:230-7. 2010
    ..This study emphasizes the significance of mutation screening for diagnosis, risk-assessment, and mutation-site specific management in LQTS patients...
  3. pmc Transcription profiling of HCN-channel isotypes throughout mouse cardiac development
    Patrick A Schweizer
    Universitatsklinikum Heidelberg, Innere Medizin III, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Basic Res Cardiol 104:621-9. 2009
    ..Furthermore, constantly low HCN transcription in adult myocardium may be required to prevent atrial and ventricular arrhythmogenesis...
  4. ncbi request reprint Modification of choline acetyltransferase by integration of green fluorescent protein does not affect enzyme activity and subcellular distribution
    Jan Rathenberg
    Abteilung Zellphysiologie, Max Planck Institut fur medizinische Forschung, Jahnstrasse 29, 69120 Heidelberg, Germany
    Cell Tissue Res 308:1-6. 2002
    ..In primary neurons the fluorescence was present in the soma and neuritic processes. Hence, this construct will be useful for analyzing the expression and subcellular distribution of ChAT-GFP in cell and tissue culture...
  5. ncbi request reprint Skipping of Exon 1 in the KCNQ1 gene causes Jervell and Lange-Nielsen syndrome
    Joerg Zehelein
    Universitatsklinikum Heidelberg, Innere Medizin III, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    J Biol Chem 281:35397-403. 2006
    ..These data suggest mechanisms that prevent production of truncated KCNQ1 channel subunits in cardiomyocytes of individuals heterozygous for the mutant allele...
  6. ncbi request reprint Cardiac-specific activation of Cre expression at late fetal development
    Jan P Opherk
    Max Planck Institut fur medizinische Forschung, Abteilung Zellphysiologie, Heidelberg, Germany
    Biochem Biophys Res Commun 359:209-13. 2007
    ..The delayed onset of Cre activity in cTnI-Cre mice could provide a useful genetic tool to evaluate the function of loxP targeted cardiac genes without interference of recombination during early heart development...
  7. ncbi request reprint Atrial-radiofrequency catheter ablation mediated targeting of mesenchymal stromal cells
    Patrick A Schweizer
    Innere Medizin III, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Stem Cells 25:1546-51. 2007
    ..This method presents a new strategy for cardiac stem cell application leading to an efficient guidance of MSCs into the myocardium. Disclosure of potential conflicts of interest is found at the end of this article...
  8. ncbi request reprint Dominant-negative I(Ks) suppression by KCNQ1-deltaF339 potassium channels linked to Romano-Ward syndrome
    Dierk Thomas
    Universitätsklinik Heidelberg, Innere Medizin III, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Cardiovasc Res 67:487-97. 2005
    ..In this study, we investigate and discuss dominant-negative I(Ks) current reduction by a KCNQ1 deletion mutation identified in a RWS family...