Yulia V Gerasimova

Summary

Publications

  1. doi request reprint RNA-hydrolyzing activity of human serum albumin and its recombinant analogue
    Yulia V Gerasimova
    Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia
    Bioorg Med Chem Lett 20:1427-31. 2010
  2. pmc Folding of 16S rRNA in a signal-producing structure for the detection of bacteria
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816 USA
    Angew Chem Int Ed Engl 52:10586-8. 2013
  3. pmc Detection of bacterial 16S rRNA using a molecular beacon-based X sensor
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816, USA
    Biosens Bioelectron 41:386-90. 2013
  4. pmc DNA nanotechnology for nucleic acid analysis: DX motif-based sensor
    Dmitry M Kolpashchikov
    Chemistry Department, University of Central Florida, Orlando, FL 32816, USA
    Chembiochem 12:2564-7. 2011
  5. pmc Molecular-beacon-based tricomponent probe for SNP analysis in folded nucleic acids
    Camha Nguyen
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816, USA
    Chemistry 17:13052-8. 2011
  6. doi request reprint Detection of SNP-containing human DNA sequences using a split sensor with a universal molecular beacon reporter
    Yulia V Gerasimova
    Department of Chemistry, University of Central Florida, Orlando, FL, USA
    Methods Mol Biol 1039:69-80. 2013
  7. doi request reprint Connectable DNA logic gates: OR and XOR logics
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd Orlando, FL 32816 2366, USA
    Chem Asian J 7:534-40. 2012
  8. pmc Enzyme-assisted binary probe for sensitive detection of RNA and DNA
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, Orlando, FL 32816, USA
    Chem Commun (Camb) 46:8761-3. 2010
  9. pmc A single molecular beacon probe is sufficient for the analysis of multiple nucleic acid sequences
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, 4000 Central Florida Boulevard, Orlando, FL 32816, USA
    Chembiochem 11:1762-8. 2010
  10. doi request reprint Deoxyribozyme cascade for visual detection of bacterial RNA
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816 USA
    Chembiochem 14:2087-90. 2013

Collaborators

Detail Information

Publications12

  1. doi request reprint RNA-hydrolyzing activity of human serum albumin and its recombinant analogue
    Yulia V Gerasimova
    Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia
    Bioorg Med Chem Lett 20:1427-31. 2010
    ..Analysis of pH dependence suggests an acid-base mechanism of catalysis. The catalytic activity and substrate specificity of albumin in RNA hydrolysis distinguish it from human ribonucleases...
  2. pmc Folding of 16S rRNA in a signal-producing structure for the detection of bacteria
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816 USA
    Angew Chem Int Ed Engl 52:10586-8. 2013
    ..Sixty-four DNA strands hybridize to 16S rRNA to form 32 deoxyribozyme catalytic cores that produce a fluorescent signal. The approach allows detection of 0.6 pM 16S rRNA, or about 3×10(4) bacterial cells in a PCR-free format...
  3. pmc Detection of bacterial 16S rRNA using a molecular beacon-based X sensor
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816, USA
    Biosens Bioelectron 41:386-90. 2013
    ..17 nM. The high specificity of the analysis was proven by differentiating Bacillus subtilis from E. coli 16S rRNA sequences. The sensor responds to the presence of the analyte within seconds...
  4. pmc DNA nanotechnology for nucleic acid analysis: DX motif-based sensor
    Dmitry M Kolpashchikov
    Chemistry Department, University of Central Florida, Orlando, FL 32816, USA
    Chembiochem 12:2564-7. 2011
    ..The sensor uses a molecular beacon probe and three adaptor strands to form a five-stranded assembly, a DX-tile, with a specific analyte. This sensor is a highly selective and affordable tool for the real-time analysis of DNA and RNA...
  5. pmc Molecular-beacon-based tricomponent probe for SNP analysis in folded nucleic acids
    Camha Nguyen
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816, USA
    Chemistry 17:13052-8. 2011
    ..The tricomponent probe promises to simplify nucleic acid analysis at ambient temperatures in such applications as in vivo RNA monitoring, detection of pathogens, and single nucleotide polymorphism (SNP) genotyping by DNA microarrays...
  6. doi request reprint Detection of SNP-containing human DNA sequences using a split sensor with a universal molecular beacon reporter
    Yulia V Gerasimova
    Department of Chemistry, University of Central Florida, Orlando, FL, USA
    Methods Mol Biol 1039:69-80. 2013
    ..It is cost-efficient since it utilizes the same molecular beacon probe for the analysis of many nucleic acid sequences. ..
  7. doi request reprint Connectable DNA logic gates: OR and XOR logics
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd Orlando, FL 32816 2366, USA
    Chem Asian J 7:534-40. 2012
    ..The design of the logic gates presented here may contribute to the development of the first biocompatible molecular computer...
  8. pmc Enzyme-assisted binary probe for sensitive detection of RNA and DNA
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, Orlando, FL 32816, USA
    Chem Commun (Camb) 46:8761-3. 2010
    ..Requiring only two new unmodified DNA oligonucleotides for the detection of each new analyte, the assay is an efficient tool for low-cost analysis of multiple analytes...
  9. pmc A single molecular beacon probe is sufficient for the analysis of multiple nucleic acid sequences
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, 4000 Central Florida Boulevard, Orlando, FL 32816, USA
    Chembiochem 11:1762-8. 2010
    ..In this study one universal MB probe was used to genotype three human polymorphic sites. This approach promises to reduce the cost of multiplex real-time assays and improve the accuracy of single-nucleotide polymorphism genotyping...
  10. doi request reprint Deoxyribozyme cascade for visual detection of bacterial RNA
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816 USA
    Chembiochem 14:2087-90. 2013
    ..The detection limit is 12.5 ng by the naked eye, with the ability to differentiate between closely related pathogenic and nonpathogenic species...
  11. pmc RNA-cleaving deoxyribozyme sensor for nucleic acid analysis: the limit of detection
    Yulia V Gerasimova
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816 2366, USA
    Chembiochem 11:811-7, 729. 2010
    ..The expressions for the theoretical LOD and DE can be used to evaluate nucleic acid and protein enzymes for their application as biosensing platforms...
  12. pmc Two-component covalent inhibitor
    Evan M Cornett
    Chemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816, USA
    Bioorg Med Chem 21:1988-91. 2013
    ..Our findings suggest that TCCI approach has advantages in inactivation of biopolymers in complex multi-component systems...