sophia george

Summary

Affiliation: University of Toronto
Location: Toronto, Canada
Summary:
ovarian cancer
high-grade serous ovarian cancer
BRCA1/2
fallopian tubes
embryonic stem cells
VEGF

Publications

  1. pmc Developmental and adult phenotyping directly from mutant embryonic stem cells
    Sophia H L George
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada M5G 1X5
    Proc Natl Acad Sci U S A 104:4455-60. 2007
  2. doi Functional immobilization of signaling proteins enables control of stem cell fate
    Kristin Alberti
    Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials, Hohe Str 6, D 01069 Dresden, Germany
    Nat Methods 5:645-50. 2008
  3. doi Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner
    Kelly A Purpura
    Department of Chemical Engineering and Applied Chemistry, Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada
    Stem Cells 26:2832-42. 2008
  4. doi Identification of abrogated pathways in fallopian tube epithelium from BRCA1 mutation carriers
    Sophia Hl George
    Department of Pathology, University Health Network, Toronto, Ontario, Canada
    J Pathol 225:106-17. 2011

Collaborators

Detail Information

Publications5

  1. pmc Developmental and adult phenotyping directly from mutant embryonic stem cells
    Sophia H L George
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada M5G 1X5
    Proc Natl Acad Sci U S A 104:4455-60. 2007
    ....
  2. doi Functional immobilization of signaling proteins enables control of stem cell fate
    Kristin Alberti
    Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials, Hohe Str 6, D 01069 Dresden, Germany
    Nat Methods 5:645-50. 2008
    ..The introduced method allows for the robust investigation of cell fate responses from interface-immobilized ligands...
  3. doi Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner
    Kelly A Purpura
    Department of Chemical Engineering and Applied Chemistry, Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada
    Stem Cells 26:2832-42. 2008
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  4. doi Identification of abrogated pathways in fallopian tube epithelium from BRCA1 mutation carriers
    Sophia Hl George
    Department of Pathology, University Health Network, Toronto, Ontario, Canada
    J Pathol 225:106-17. 2011
    ..The altered expression profiles in histologically normal tubal epithelium from BRCA1 heterozygotes suggest that these cells may respond differently to microenvironmental stresses...