Joaquim Gea

Summary

Publications

  1. ncbi request reprint Respiratory diseases and muscle dysfunction
    Joaquim Gea
    Servei de Pneumologia, Hospital del Mar IMIM, Departament de Ciències Experimentals i de la Salut CEXS, Universitat Pompeu Fabra, CIBER de Enfermedades Respiratorias ISC III, Barcelona, Catalunya, Spain
    Expert Rev Respir Med 6:75-90. 2012
  2. ncbi request reprint [Nutritional abnormalities in chronic obstructive pulmonary disease]
    Joaquim Gea
    Servicio de Neumologia, Hospital del Mar IMIM, Barcelona, España Departamento de Ciencias Experimentales y de la Salud CEXS, Universitat Pompeu Fabra, Barcelona, España Centro de Investigación Biomédica en Red de Enfermedades Respiratorias CIBERES, Instituto de Salud Carlos III, Bunyola, Mallorca, España Electronic address
    Med Clin (Barc) 143:78-84. 2014
  3. doi request reprint Pathophysiology of muscle dysfunction in COPD
    Joaquim Gea
    Servei de Pneumologia, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain
    J Appl Physiol (1985) 114:1222-34. 2013
  4. ncbi request reprint Evaluation of the respiratory muscular function by means of diaphragmatic mechanomyographic signals in COPD patients
    Leonardo Sarlabous
    Dept ESAII, Universitat Politecnica de Catalunya, Institut de Bioenginyeria de Catalunya, Barcelona, Spain
    Conf Proc IEEE Eng Med Biol Soc 2009:3925-8. 2009
  5. doi request reprint Rényi entropy and Lempel-Ziv complexity of mechanomyographic recordings of diaphragm muscle as indexes of respiratory effort
    Abel Torres
    Department ESAII, Universitat Politecnica de Catalunya, Institut de Bioenginyeria de Catalunya, Barcelona, Spain
    Conf Proc IEEE Eng Med Biol Soc 2008:2112-5. 2008
  6. doi request reprint Cigarette smoke-induced oxidative stress: A role in chronic obstructive pulmonary disease skeletal muscle dysfunction
    Esther Barreiro
    Pulmonology Department, Municipal Institute of Medical Research, Hospital del Mar, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain
    Am J Respir Crit Care Med 182:477-88. 2010
  7. doi request reprint [Inflammation and oxidative stress in respiratory and limb muscles of patients with severe sepsis]
    Sergio Pascual-Guardia
    Unidad de Investigación en Músculo y Aparato Respiratorio, Servicio de Neumologia, Instituto Municipal de Investigación Médica IMIM Hospital del Mar, Parc de Salut Mar, Departamento de Ciencias Experimentales y de la Salud, Universitat Pompeu Fabra, Parc de Recerca Biomédica de Barcelona PRBB, Barcelona, Espana
    Med Clin (Barc) 141:194-200. 2013
  8. ncbi request reprint Redox balance and cellular inflammation in the diaphragm, limb muscles, and lungs of mechanically ventilated rats
    Judith Marin-Corral
    Institut Municipal d Investigació Mèdica Hospital del Mar, Parc de Recerca Biomedica de Barcelona, Department of Medicine, Medical School, Universitat Autonoma de Barcelona, Barcelona, Spain
    Anesthesiology 112:384-94. 2010
  9. ncbi request reprint Noninvasive measurement of inspiratory muscle performance by means of diaphragm muscle mechanomyographic signals in COPD patients during an incremental load respiratory test
    Abel Torres
    Dept ESAII, Universitat Politecnica de Catalunya, Institut de Bioenginyeria de Catalunya IBEC and CIBER de Bioingeniería, Biomateriales y Nanomedicina CIBERBBN, Barcelona, Spain
    Conf Proc IEEE Eng Med Biol Soc 2010:2493-6. 2010
  10. ncbi request reprint Aging, sex differences, and oxidative stress in human respiratory and limb muscles
    Esther Barreiro
    Muscle and Respiratory System Research Unit and Respiratory Medicine Department, IMIM Hospital del Mar, Universitat Pompeu Fabra, c Dr Aiguader, 80, Barcelona E 08003, Spain
    Free Radic Biol Med 41:797-809. 2006

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Respiratory diseases and muscle dysfunction
    Joaquim Gea
    Servei de Pneumologia, Hospital del Mar IMIM, Departament de Ciències Experimentals i de la Salut CEXS, Universitat Pompeu Fabra, CIBER de Enfermedades Respiratorias ISC III, Barcelona, Catalunya, Spain
    Expert Rev Respir Med 6:75-90. 2012
    ..A multidimensional therapeutic approach is recommended, including pulmonary rehabilitation, an adequate level of physical activity, ventilatory support and nutritional interventions...
  2. ncbi request reprint [Nutritional abnormalities in chronic obstructive pulmonary disease]
    Joaquim Gea
    Servicio de Neumologia, Hospital del Mar IMIM, Barcelona, España Departamento de Ciencias Experimentales y de la Salud CEXS, Universitat Pompeu Fabra, Barcelona, España Centro de Investigación Biomédica en Red de Enfermedades Respiratorias CIBERES, Instituto de Salud Carlos III, Bunyola, Mallorca, España Electronic address
    Med Clin (Barc) 143:78-84. 2014
    ....
  3. doi request reprint Pathophysiology of muscle dysfunction in COPD
    Joaquim Gea
    Servei de Pneumologia, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain
    J Appl Physiol (1985) 114:1222-34. 2013
    ..In the present review we examine the current state of the art of the pathophysiology of muscle dysfunction in COPD...
  4. ncbi request reprint Evaluation of the respiratory muscular function by means of diaphragmatic mechanomyographic signals in COPD patients
    Leonardo Sarlabous
    Dept ESAII, Universitat Politecnica de Catalunya, Institut de Bioenginyeria de Catalunya, Barcelona, Spain
    Conf Proc IEEE Eng Med Biol Soc 2009:3925-8. 2009
    ..This behaviour is similar for both MMGl and MMGr signals. Results suggest that the use of MMG signals could be potentially useful for the evaluation of the respiratory muscular function in COPD patients...
  5. doi request reprint Rényi entropy and Lempel-Ziv complexity of mechanomyographic recordings of diaphragm muscle as indexes of respiratory effort
    Abel Torres
    Department ESAII, Universitat Politecnica de Catalunya, Institut de Bioenginyeria de Catalunya, Barcelona, Spain
    Conf Proc IEEE Eng Med Biol Soc 2008:2112-5. 2008
    ..Our results suggest that these non-linear techniques are useful to detect and quantify changes in the respiratory effort by analyzing MMG respiratory signals...
  6. doi request reprint Cigarette smoke-induced oxidative stress: A role in chronic obstructive pulmonary disease skeletal muscle dysfunction
    Esther Barreiro
    Pulmonology Department, Municipal Institute of Medical Research, Hospital del Mar, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain
    Am J Respir Crit Care Med 182:477-88. 2010
    ..Inflammation and oxidative stress contribute to muscle dysfunction in patients with chronic obstructive pulmonary disease (COPD). Oxidants contained in cigarette smoke (CS) induce adverse effects on tissues through oxidative phenomena...
  7. doi request reprint [Inflammation and oxidative stress in respiratory and limb muscles of patients with severe sepsis]
    Sergio Pascual-Guardia
    Unidad de Investigación en Músculo y Aparato Respiratorio, Servicio de Neumologia, Instituto Municipal de Investigación Médica IMIM Hospital del Mar, Parc de Salut Mar, Departamento de Ciencias Experimentales y de la Salud, Universitat Pompeu Fabra, Parc de Recerca Biomédica de Barcelona PRBB, Barcelona, Espana
    Med Clin (Barc) 141:194-200. 2013
    ..Levels of oxidative stress and inflammation were evaluated in a respiratory muscle, the external intercostal, and a limb muscle, the vastus lateralis, of patients with sepsis...
  8. ncbi request reprint Redox balance and cellular inflammation in the diaphragm, limb muscles, and lungs of mechanically ventilated rats
    Judith Marin-Corral
    Institut Municipal d Investigació Mèdica Hospital del Mar, Parc de Recerca Biomedica de Barcelona, Department of Medicine, Medical School, Universitat Autonoma de Barcelona, Barcelona, Spain
    Anesthesiology 112:384-94. 2010
    ..The authors aimed to explore whether high VT mechanical ventilation per se induces early oxidative stress and inflammation in the diaphragm, limb muscles, and lungs of healthy rats exposed to ventilator-induced lung injury...
  9. ncbi request reprint Noninvasive measurement of inspiratory muscle performance by means of diaphragm muscle mechanomyographic signals in COPD patients during an incremental load respiratory test
    Abel Torres
    Dept ESAII, Universitat Politecnica de Catalunya, Institut de Bioenginyeria de Catalunya IBEC and CIBER de Bioingeniería, Biomateriales y Nanomedicina CIBERBBN, Barcelona, Spain
    Conf Proc IEEE Eng Med Biol Soc 2010:2493-6. 2010
    ..45 - right: 0.63; Multistate Lempel-Ziv, left: 0.39 - right: 0.64). These results suggest that the information provided by MMG signals could be used in order to evaluate the respiratory effort and the muscular efficiency in COPD patients...
  10. ncbi request reprint Aging, sex differences, and oxidative stress in human respiratory and limb muscles
    Esther Barreiro
    Muscle and Respiratory System Research Unit and Respiratory Medicine Department, IMIM Hospital del Mar, Universitat Pompeu Fabra, c Dr Aiguader, 80, Barcelona E 08003, Spain
    Free Radic Biol Med 41:797-809. 2006
    ....
  11. ncbi request reprint Clinical outcomes of expiratory muscle training in severe COPD patients
    Susana Mota
    Departament de Pneumologia, Hospital de la Santa Creu i de Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain
    Respir Med 101:516-24. 2007
    ..Although both general and inspiratory muscle training have shown clinical benefits, the effects of specific expiratory muscle training remain controversial...
  12. ncbi request reprint Does oxidative stress modulate limb muscle atrophy in severe COPD patients?
    Clara Fermoselle
    Pulmonology Dept, Muscle and Respiratory System Research Unit, IMIM Hospital del Mar, Health and Experimental Sciences Dept, Universitat Pompeu Fabra, PRBB, Barcelona, Spain
    Eur Respir J 40:851-62. 2012
    ..Oxidative stress does not seem to directly modulate muscle protein loss in these patients...
  13. doi request reprint Mass of intercostal muscles associates with risk of multiple exacerbations in COPD
    Roberto Güerri
    Servei de Medicina Interna, Hospital del Mar, Barcelona, Spain
    Respir Med 104:378-88. 2010
    ..We hypothesized that a decrease in respiratory muscle mass is associated with increased risk of multiple hospital admissions due to acute exacerbations of the disease...
  14. doi request reprint UCP3 overexpression neutralizes oxidative stress rather than nitrosative stress in mouse myotubes
    Esther Barreiro
    Muscle and Respiratory System Research Unit Pneumology Department, IMIM Hospital del Mar, Centro de Investigación en Red de Enfermedades Respiratorias CibeRes, CEXS, Universitat Pompeu Fabra, Barcelona Biomedical Research Park, Barcelona, Spain
    FEBS Lett 583:350-6. 2009
    ..We conclude that protein oxidation rather than nitration is neutralized by UPC3 overexpression in mouse myotubes exposed to abundant reactive oxygen species...
  15. doi request reprint Association between Ω3 and Ω6 fatty acid intakes and serum inflammatory markers in COPD
    Jordi de Batlle
    Centre for Research in Environmental Epidemiology CREAL, Barcelona, Spain
    J Nutr Biochem 23:817-21. 2012
    ..96; P=.034) and CRP (OR=1.95; P=.039) concentrations. Therefore, this study provides the first evidence of an association between dietary intake of omega-3 and omega-6 fatty acids and serum inflammatory markers in COPD patients...
  16. doi request reprint Muscle and blood redox status after exercise training in severe COPD patients
    Diego A Rodriguez
    Servei de Pneumologia, Hospital Clinic, IDIBAPS, Universitat de Barcelona, Barcelona, Catalonia, Spain
    Free Radic Biol Med 52:88-94. 2012
    ..In addition, in these patients, resting protein oxidation levels correlate between skeletal muscle and blood compartments...
  17. doi request reprint Dietary modulation of oxidative stress in chronic obstructive pulmonary disease patients
    Jordi de Batlle
    Centre for Research in Environmental Epidemiology CREAL, Barcelona, Spain
    Free Radic Res 44:1296-303. 2010
    ..These results provide new data for a potential dietary modulation of systemic oxidative stress in COPD patients, particularly in those that continue smoking...
  18. ncbi request reprint Application of the empirical mode decomposition method to the analysis of respiratory mechanomyographic signals
    Abel Torres
    Departament of Biomedical Signal and Systems, at the Biomedical Engineering Research Centre, Universitat Politecnica de Catalunya, Barcelona, Spain
    Conf Proc IEEE Eng Med Biol Soc 2007:1566-9. 2007
    ..The obtained correlation coefficients between respiratory and MMG parameters were higher than the ones obtained with a Wavelet multiresolution decomposition method utilized in a previous work...
  19. ncbi request reprint [Determination of maximal diaphragm strength in chronic obstructive pulmonary disease: cervical magnetic stimulation versus traditional sniff maneuver]
    Juana Martínez-Llorens
    Servei de Medicina Respiratòria, Unitat de Recerca en Múscul i Aparell Respiratori URMAR, Hospital del Mar IMIM, Departament CEXS, Universitat Pompeu Fabra, Barcelona, Espana
    Arch Bronconeumol 42:509-15. 2006
    ..The aim of the present study was to compare this inhalation technique with traditional voluntary forced inspiration (sniff test) in a group of patients with chronic obstructive pulmonary disease (COPD)...
  20. ncbi request reprint Molecular and physiological events in respiratory muscles and blood of rats exposed to inspiratory threshold loading
    Marisol Domínguez-Álvarez
    Respiratory Medicine Muscle and Respiratory System Research Unit, IMIM Hospital del Mar, Health and Experimental Sciences Department CEXS, Universitat Pompeu Fabra, Barcelona Biomedical Research Park PRBB, Barcelona, Catalonia, Spain Centro de Investigación en Red de Enfermedades Respiratorias CIBERES, Instituto de Salud Carlos III ISCIII, Bunyola, Majorca, Balearic Islands, Spain
    Transl Res 163:478-93. 2014
    ..We conclude that TNF-α synthesized by inflammatory cells or myofibers could have differential effects on muscle structure and function in response to chronic, noninvasive, high-intensity inspiratory threshold loading. ..
  21. ncbi request reprint [Activation of satellite cells in the intercostal muscles of patients with chronic obstructive pulmonary disease]
    Juana Martínez-Llorens
    Servei de Pneumologia, Hospital del Mar IMIM, Barcelona, Espana
    Arch Bronconeumol 44:239-44. 2008
    ..The aim of this study was to analyze the number and activation of those cells along with the expression of markers of microstructural damage that are frequently associated with regeneration...
  22. pmc Factors affecting the relationship between psychological status and quality of life in COPD patients
    Eva Balcells
    Servei de Pneumologia, Hospital del Mar IMIM, Passeig Maritim 25 29, 08003 Barcelona, Spain
    Health Qual Life Outcomes 8:108. 2010
    ....
  23. doi request reprint [Phenotypic characterization and course of chronic obstructive pulmonary disease in the PAC-COPD Study: design and methods]
    J Garcia-Aymerich
    Centre for Research in Environmental Epidemiology CREAL, Institut Municipal d Investigació Mèdica Hospital del Mar, Universitat Pompeu Fabra, CIBER de Epidemiología y Salud Pública CIBERESP, Barcelona, Espana
    Arch Bronconeumol 45:4-11. 2009
    ....
  24. doi request reprint Injury of peripheral muscles in smokers with chronic obstructive pulmonary disease
    Mauricio Orozco-Levi
    Group of Research in Function, Injury and Immune Response LIF, Hospital del Mar, Barcelona, Catalonia, Spain
    Ultrastruct Pathol 36:228-38. 2012
    ..These findings support the theory that systemic factors with deleterious effect are acting on peripheral muscles of smokers with COPD, increasing the susceptibility of the muscle fibers to membrane and sarcomere injury...
  25. doi request reprint Nasal inspiratory pressure: an alternative for the assessment of inspiratory muscle strength?
    Juana Martínez-Llorens
    Servei de Pneumologia URMAR, Hospital del Mar IMIM Parc de Salut Mar, CEXS, Universitat Pompeu Fabra, CIBER de Enfermedades Respiratorias, ISC III Barcelona, Spain
    Arch Bronconeumol 47:169-75. 2011
    ..However, since this manoeuvre presents certain problems, alternative techniques have been developed over the last few years. One of the most promising is determination of sniff nasal inspiratory pressure (SNIP)...
  26. ncbi request reprint [Non-invasive functional evaluation of the reserve in fatigue and the diaphragm structure using transthoracic echography in B and M modes]
    Mauricio Orozco-Levi
    Servicio de Neumologia, Hospital del Mar, Barcelona, Spain
    Arch Bronconeumol 46:571-9. 2010
    ..The present study was designed to evaluate the potential use of echography as a non-invasive method to fulfil these objectives...
  27. ncbi request reprint [Improvement in quality of life and exercise capacity without muscular biology changes after general training in patients with severe chronic obstructive pulmonary disease]
    Sergio Pascual-Guardia
    Grupo de Investigación en EPOC y Cáncer de Pulmón, Servicio de Neumologia, Instituto Municipal de Investigación Médica IMIM Hospital del Mar, Parc de Salut Mar, Departamento de Ciencias Experimentales y de la Salud, Universitat Pompeu Fabra, Parc de Recerca Biomédica de Barcelona PRBB, Barcelona, Espana
    Med Clin (Barc) 140:200-6. 2013
    ....
  28. doi request reprint Global muscle dysfunction as a risk factor of readmission to hospital due to COPD exacerbations
    Jordi Vilaro
    FCS Blanquerna, Universitat Ramon Llull, Barcelona, Spain
    Respir Med 104:1896-902. 2010
    ..We hypothesise that most of these risk factors may have a converging and deleterious effects on both respiratory and peripheral muscle function in COPD patients...
  29. ncbi request reprint [Global muscle dysfunction and exacerbation of COPD: a cohort study]
    Juana M Martinez-Llorens
    Unitat de Recerca en Múscul, Institut Municipal d Investigacio Medica, Servei de Pneumologia, Hospital del Mar, Universitat Autonoma, CEXS Universitat Pompeu Fabra, Barcelona, Spain
    Med Clin (Barc) 122:521-7. 2004
    ..The purpose of this study was to evaluate on a prospective fashion the effects of clinical relapses of chronic obstructive pulmonary disease (COPD) on both peripheral and respiratory skeletal muscle functions...
  30. ncbi request reprint Cigarette smoke-induced oxidative stress in skeletal muscles of mice
    Esther Barreiro
    Pulmonology Department Muscle and Respiratory System Research Unit, URMAR, IMIM Hospital del Mar, Health and Experimental Sciences Department, Universitat Pompeu Fabra, Barcelona, Spain
    Respir Physiol Neurobiol 182:9-17. 2012
    ..In AKR/J mice, chronic exposure to CS induces lung emphysema concomitantly with greater oxidative modifications on muscle proteins in both respiratory and limb muscles, and systemic inflammation...
  31. ncbi request reprint Multistate Lempel-Ziv (MLZ) index interpretation as a measure of amplitude and complexity changes
    Leonardo Sarlabous
    Dept ESAII, Universitat Politecnica de Catalunya, Institut de Bioenginyeria de Catalunya IBEC, Barcelona, Spain
    Conf Proc IEEE Eng Med Biol Soc 2009:4375-8. 2009
    ..Furthermore, it has been observed that the MLZ index with high number of levels practically is not affected by the existence of impulsive, sinusoidal, constant and Gaussian noises compared with the RMS amplitude parameter...
  32. doi request reprint High-intensity vs. sham inspiratory muscle training in patients with chronic heart failure: a prospective randomized trial
    Ester Marco
    Physical Medicine and Rehabilitation Department, Hospital del Mar, Barcelona, Catalonia, Spain
    Eur J Heart Fail 15:892-901. 2013
    ..The purpose of this study was to evaluate the effectiveness, feasibility, and safety of a 4-week high-intensity inspiratory muscle training (hi-IMT) in patients with chronic heart failure (CHF)...
  33. ncbi request reprint Dual morphometrical changes of the deltoid muscle in patients with COPD
    Nuria Hernandez
    Grup de Recerca de Pneumologia, URRA Hospital del Mar IMIM CEXS, Universitat Pompeu Fabra, Barcelona, Spain
    Respir Physiol Neurobiol 134:219-29. 2003
    ..We conclude that factors with opposite effect (promotion of either atrophy or hypertrophy) exert relevant roles in the histomorphometrical characteristics of the deltoid muscles in COPD patients...
  34. pmc Oxidative stress in the external intercostal muscles of patients with obstructive sleep apnoea
    Esther Barreiro
    Muscle and Respiratory System Research Unit, IMIM Hospital del Mar, Centro de Investigación en Red de Enfermedades Respiratorias, Experimental Sciences and Health Department CEXS, Universitat Pompeu Fabra, PRBB, Barcelona, Spain
    Thorax 62:1095-101. 2007
    ..It was therefore hypothesised that oxidative stress levels would be increased in these muscles, and that treatment with continuous positive airway pressure (CPAP) would modify the oxidative stress levels and improve muscle dysfunction...
  35. ncbi request reprint Oxidative stress time course in the rat diaphragm after freezing-thawing cycles
    Jacobo Sellares
    Muscle and Respiratory System Research Unit, Respiratory Medicine Department, IMIM Hospital del Mar, Universitat Pompeu Fabra, c Dr Aiguader, 80, E 08003 Barcelona, Spain
    Respir Physiol Neurobiol 155:156-66. 2007
    ..Protein oxidation was significantly increased in the rat diaphragms exposed to freezing-thawing cycles of different time lengths, while Mn-SOD was substantially reduced in all muscles...
  36. ncbi request reprint Do epigenetic events take place in the vastus lateralis of patients with mild chronic obstructive pulmonary disease?
    Ester Puig-Vilanova
    Pulmonology Department Muscle and Respiratory System Research Unit URMAR, IMIM Hospital del Mar, Parc de Salut Mar, Health and Experimental Sciences Department CEXS, Universitat Pompeu Fabra UPF, Barcelona Biomedical Research Park PRBB, Barcelona, Spain Centro de Investigación en Red de Enfermedades Respiratorias CIBERES, Instituto de Salud Carlos III ISCIII, Madrid, Spain
    PLoS ONE 9:e102296. 2014
    ..The study of patients at early stages of their disease is of interest as they are a target for timely therapeutic interventions that may slow down the course of the disease and prevent the deleterious effects of major comorbidities. ..
  37. ncbi request reprint Endobronchial ultrasound for the diagnosis of peripheral pulmonary lesions. A controlled study with fluoroscopy
    Albert Sánchez-Font
    Servei de Pneumologia, Hospital del Mar Parc de Salut Mar, Universitat Autònoma de Barcelona y Universitat Pompeu Fabra, Ciber de enfermedades respiratorias CIBERES, ISCIII, Barcelona, España Electronic address
    Arch Bronconeumol 50:166-71. 2014
    ..Endobronchial ultrasound (EBUS) can increase the diagnostic yield of bronchoscopic diagnosis of PPL...
  38. doi request reprint The day hospital: analysis of results, costs and management of pneumology resources
    Francesc Cots
    Servei d Epidemiologia i Avaluació, Hospital del Mar IMIM, Parc de Salut Mar, CIBERESP, ISC III, Barcelona, Espana
    Arch Bronconeumol 49:54-62. 2013
    ..Day hospital units specialized in pulmonology are a relatively new instrument for providing care to complex respiratory patients. However, the number of studies focused on the efficacy and efficiency of day hospitals is scarce...
  39. ncbi request reprint The "oil well analogy" as a comprehensive interpretation of factors leading to muscle injury and wasting
    Mauricio Orozco-Levi
    Muscle and Respiratory System Research Unit URMAR, Municipal Institute of Medical Research IMIM, Respiratory Medicine Department, Hospital del Mar, CEXS, Universitat Pompeu Fabra, Barcelona, Spain
    Ultrastruct Pathol 30:247-52. 2006
    ....
  40. doi request reprint Oxidative stress and inflammation in the normal airways and blood of patients with lung cancer and COPD
    Esther Barreiro
    Pulmonology Department, Muscle and Respiratory System Research Unit, IMIM Institut Hospital del Mar, Parc de Salut Mar, and Health and Experimental Sciences Department, Universitat Pompeu Fabra, Universitat Autonoma de Barcelona, Parc de Recerca Biomedica de Barcelona, E 08003 Barcelona, Spain Centro de Investigación en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Bunyola, Majorca, Balearic Islands, Spain Electronic address
    Free Radic Biol Med 65:859-71. 2013
    ..Furthermore, the potential predictive value for LC development of these molecular events warrants attention and should be explored in future larger longitudinal studies. ..
  41. ncbi request reprint [The evolution of the human species: a long journey for the respiratory system]
    Joaquim Gea
    Servicio de Neumologia, Hospital del Mar, Barcelona, Espana
    Arch Bronconeumol 44:263-70. 2008
    ..The pulmonary ventilation and perfusion gradients moved from a dorsoventral to a craniocaudal axis, while the structural organization of the respiratory muscles underwent only minor changes...
  42. ncbi request reprint Muscle glucose metabolism in chronic obstructive pulmonary disease patients
    Antonio Sancho-Muñoz
    Servicio de Neumologia, Hospital del Mar IMIM, Barcelona, Espana
    Arch Bronconeumol 50:221-7. 2014
    ..Metabolic changes in muscle are difficult to study in vivo, due to the lack of non-invasive techniques. Our aim was to evaluate metabolic activity simultaneously in various muscle groups in COPD patients...
  43. doi request reprint Characteristics of patients admitted for the first time for COPD exacerbation
    Eva Balcells
    Servei de Pneumologia, Hospital del Mar IMIM, Passeig Maritim 25 29, Barcelona, Spain
    Respir Med 103:1293-302. 2009
    ..This study describes the characteristics of a large sample of patients hospitalised for the first time for a chronic obstructive pulmonary disease (COPD) exacerbation...
  44. ncbi request reprint Prospective comparison of severity scores for predicting mortality in community-acquired pneumonia
    Sonia Luque
    Pharmacy Department, Hospital del Mar, Barcelona, Parc de Salut Mar, Passeig Maritim 25 29, 08003 Barcelona, Spain
    Rev Esp Quimioter 25:147-54. 2012
    ..So far, which score performs better in CAP remains controversial. The objective was to compare PSI and CURB-65 and the general model, MPM-II, for predicting 30-day mortality in patients admitted with CAP...
  45. ncbi request reprint [Short-stay respiratory unit: a new option for inpatient care]
    Joan Maria Broquetas
    Servicio de Neumologia, Hospital del Mar IMIM, Barcelona, Espana
    Arch Bronconeumol 44:252-6. 2008
    ..The aim of this study was to analyze the impact of a new instrument --a short-stay respiratory unit-- on the quality of care delivered by the respiratory medicine department of a tertiary care hospital...
  46. ncbi request reprint Inspiratory muscle training in patients with chronic obstructive pulmonary disease: structural adaptation and physiologic outcomes
    Alba Ramirez-Sarmiento
    Servei de Pneumologia, Hospital del Mar Grup de Recerca de Pneumologia, Unitat de Recerca Respiratoria i Ambiental, Barcelona, Spain
    Am J Respir Crit Care Med 166:1491-7. 2002
    ..No changes were observed in the control muscle. The study demonstrates that inspiratory training induces a specific functional improvement of the inspiratory muscles and adaptive changes in the structure of external intercostal muscles...
  47. ncbi request reprint [Update on the mechanisms of muscle dysfunction in COPD]
    Joaquim Gea
    Servicio de Neumología Hospital del Mar, Unidad de Investigación en Músculo y Aparato Respiratorio URMAR, IMIM, Passeig Marítim 27, Barcelona, Spain
    Arch Bronconeumol 44:328-37. 2008
    ..All of these factors interact in different ways in each muscle group, giving rise to various phenotypes and specific contractile capacities...
  48. doi request reprint [Skeletal muscle dysfunction in COPD]
    Joaquim Gea
    Servicio de Neumologia, Hospital del Mar IMIM, Departamento de Ciencias Experimentales y de Salud, Universidad Pompeu Fabra, CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Barcelona, Espana
    Arch Bronconeumol 45:36-41. 2009
    ..Therefore, although functional loss can develop in distinct muscular territories, the causes - and consequently the therapeutic approaches - differ, including nutritional support, muscle training and/or rest, depending on the muscle...
  49. ncbi request reprint Inspiratory pressure evaluation by means of the entropy of respiratory mechanomyographic signals
    Abel Torres
    Department of Systtems Engineering, Biomedical Engineering Research Centre, Politechnical University of Catalonia, Barcelona, Spain
    Conf Proc IEEE Eng Med Biol Soc 1:5735-8. 2006
    ..With this non linear filtering method we have obtained higher correlation coefficients (with both entropy and amplitude parameters) than with the Wavelet multiresolution technique proposed in a previous work...
  50. ncbi request reprint [Increased inspiratory oxygen fractions (FIO2) using a conventional drug delivery nebuliser]
    Joaquim Gea
    Servicio de Neumologia, Hospital del Mar, Instituto Municipal de Investigación Médica IMIM, Universitat Pompeu Fabra, Barcelona, Espana
    Arch Bronconeumol 46:230-7. 2010
    ..The purpose of this approach is to avoid the risks inherent in breathing high inspiratory oxygen fractions (FIO(2))...
  51. ncbi request reprint Text mining and medicine: usefulness in respiratory diseases
    David Piedra
    Instituto de Investigación del Hospital del Mar IMIM, Barcelona, España Electronic address
    Arch Bronconeumol 50:113-9. 2014
    ..This review aims to provide an overview of text and data mining, and of the potential usefulness of this bioinformatic technique in the exercise of care in respiratory medicine and in research in the same field. ..
  52. ncbi request reprint [Basic research in pulmonology]
    Joaquim Gea
    Servicio de Neumología URMAR, Hospital del Mar IMIM, Departament CEXS, Universitat Pompeu Fabra, CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Barcelona, Espana
    Arch Bronconeumol 44:621-8. 2008
    ..Finally, 2 studies analyzed the diagnosis and treatment of tuberculosis and other pulmonary infections...
  53. ncbi request reprint Both oxidative and nitrosative stress are associated with muscle wasting in tumour-bearing rats
    Esther Barreiro
    Muscle and Respiratory System Research Unit, IMIM and CEXS, Universitat Pompeu Fabra, Barcelona, Spain
    FEBS Lett 579:1646-52. 2005
    ....