Diego Gazzolo

Summary

Publications

  1. ncbi request reprint Biochemical markers of perinatal brain damage
    Pasquale Florio
    Department of Pediatrics, University of Siena, Siena, Italy
    Front Biosci (Schol Ed) 2:47-72. 2010
  2. pmc Sustained lung inflation in the delivery room in preterm infants at high risk of respiratory distress syndrome (SLI STUDY): study protocol for a randomized controlled trial
    Carlo Dani
    Department of Surgical and Medical Critical Care, Section of Neonatology, Careggi University Hospital, Viale Morgagni 85, Florence 50141, Italy
    Trials 14:67. 2013
  3. pmc Evaluation of splanchnic oximetry, Doppler flow velocimetry in the superior mesenteric artery and feeding tolerance in very low birth weight IUGR and non-IUGR infants receiving bolus versus continuous enteral nutrition
    Valentina Bozzetti
    Department of Neonatal Intensive Care, MBBM Foundation, San Gerardo Hospital, Via Pergolesi 33, 20900 Monza, Italy
    BMC Pediatr 12:106. 2012
  4. ncbi request reprint Antenatal glucocorticoids supplementation and central nervous system development
    Diego Gazzolo
    Department of Maternal, Fetal and Neonatal Health, C Arrigo Children s Hospital, Spalto Marengo 46, I 15100 Alessandria, Italy
    Curr Drug Metab 14:160-6. 2013
  5. ncbi request reprint Selective serotonin reuptake inhibitors in pregnancy
    V Bellissima
    Cesare Arrigo Children s Hospital, Alessandria, Italy
    Curr Med Chem 19:4554-61. 2012
  6. ncbi request reprint Measurement of urinary S100B protein concentrations for the early identification of brain damage in asphyxiated full-term infants
    Diego Gazzolo
    Department of Neonatology, Giannina Gaslini Children s University Hospital, Genoa, Italy
    Arch Pediatr Adolesc Med 157:1163-8. 2003
  7. ncbi request reprint Urinary S100B protein measurements: A tool for the early identification of hypoxic-ischemic encephalopathy in asphyxiated full-term infants
    Diego Gazzolo
    Department of Pediatrics, G Gaslini Children s University Hospital, Genoa, Italy
    Crit Care Med 32:131-6. 2004
  8. ncbi request reprint Phentolamine administration increases blood S100B protein levels in pediatric open-heart surgery patients
    D Gazzolo
    Department of Pediatrics, G Gaslini University Hospital, Genoa, Italy
    Acta Paediatr 92:1427-32. 2003
  9. doi request reprint Neuromarkers and unconventional biological fluids
    Diego Gazzolo
    Department of Maternal, Fetal and Neonatal Medicine, C Arrigo Children s Hospital, Spalto Marengo 46, Alessandria, Italy
    J Matern Fetal Neonatal Med 23:66-9. 2010
  10. ncbi request reprint S100B protein in urine of preterm newborns with ominous outcome
    Diego Gazzolo
    Department of Pediatrics, G Gaslini Children s Hospital, University of Genoa, Italy
    Pediatr Res 58:1170-4. 2005

Collaborators

Detail Information

Publications76

  1. ncbi request reprint Biochemical markers of perinatal brain damage
    Pasquale Florio
    Department of Pediatrics, University of Siena, Siena, Italy
    Front Biosci (Schol Ed) 2:47-72. 2010
    ....
  2. pmc Sustained lung inflation in the delivery room in preterm infants at high risk of respiratory distress syndrome (SLI STUDY): study protocol for a randomized controlled trial
    Carlo Dani
    Department of Surgical and Medical Critical Care, Section of Neonatology, Careggi University Hospital, Viale Morgagni 85, Florence 50141, Italy
    Trials 14:67. 2013
    ..We planned the present randomized controlled trial to confirm or refute these findings...
  3. pmc Evaluation of splanchnic oximetry, Doppler flow velocimetry in the superior mesenteric artery and feeding tolerance in very low birth weight IUGR and non-IUGR infants receiving bolus versus continuous enteral nutrition
    Valentina Bozzetti
    Department of Neonatal Intensive Care, MBBM Foundation, San Gerardo Hospital, Via Pergolesi 33, 20900 Monza, Italy
    BMC Pediatr 12:106. 2012
    ..In literature there is no consensus regarding the impact of enteral feeding on intestinal blood flow and hence regarding the best regimen and the best rate of delivering the enteral nutrition...
  4. ncbi request reprint Antenatal glucocorticoids supplementation and central nervous system development
    Diego Gazzolo
    Department of Maternal, Fetal and Neonatal Health, C Arrigo Children s Hospital, Spalto Marengo 46, I 15100 Alessandria, Italy
    Curr Drug Metab 14:160-6. 2013
    ....
  5. ncbi request reprint Selective serotonin reuptake inhibitors in pregnancy
    V Bellissima
    Cesare Arrigo Children s Hospital, Alessandria, Italy
    Curr Med Chem 19:4554-61. 2012
    ..Milder forms of depression should be treated with alternative methods. In this paper we have reviewed the literature on effects of SSRIs on embryonic, fetal and infant development...
  6. ncbi request reprint Measurement of urinary S100B protein concentrations for the early identification of brain damage in asphyxiated full-term infants
    Diego Gazzolo
    Department of Neonatology, Giannina Gaslini Children s University Hospital, Genoa, Italy
    Arch Pediatr Adolesc Med 157:1163-8. 2003
    ..We investigated whether measurements of urine levels of S100B in asphyxiated full-term newborns may be a useful tool for early detection of postasphyxia brain damage...
  7. ncbi request reprint Urinary S100B protein measurements: A tool for the early identification of hypoxic-ischemic encephalopathy in asphyxiated full-term infants
    Diego Gazzolo
    Department of Pediatrics, G Gaslini Children s University Hospital, Genoa, Italy
    Crit Care Med 32:131-6. 2004
    ..Hypoxic-ischemic encephalopathy (HIE) is one of the major causes of perinatal mortality and morbidity. To date, there are no reliable methods to detect which infants will develop brain damage after asphyxia insult...
  8. ncbi request reprint Phentolamine administration increases blood S100B protein levels in pediatric open-heart surgery patients
    D Gazzolo
    Department of Pediatrics, G Gaslini University Hospital, Genoa, Italy
    Acta Paediatr 92:1427-32. 2003
    ..This study reports the cerebral effects of phentolamine using blood S100B protein levels and the middle cerebral artery pulsatility index (MCA PI)...
  9. doi request reprint Neuromarkers and unconventional biological fluids
    Diego Gazzolo
    Department of Maternal, Fetal and Neonatal Medicine, C Arrigo Children s Hospital, Spalto Marengo 46, Alessandria, Italy
    J Matern Fetal Neonatal Med 23:66-9. 2010
    ..Results open up a new cue on the use of these markers in perinatal medicine as a key protein for investigations focusing on fetal/neonatal development...
  10. ncbi request reprint S100B protein in urine of preterm newborns with ominous outcome
    Diego Gazzolo
    Department of Pediatrics, G Gaslini Children s Hospital, University of Genoa, Italy
    Pediatr Res 58:1170-4. 2005
    ..The positive predictive value was 78.6%, the negative predictive value was 100%. Measurement of urine S100B protein levels in preterm newborns could be useful to identify newborns at higher risk of neonatal death...
  11. ncbi request reprint High maternal blood S100B concentrations in pregnancies complicated by intrauterine growth restriction and intraventricular hemorrhage
    Diego Gazzolo
    Department of Pediatrics and Neuroscience, G Gaslini Children s University Hospital, Genoa, Italy
    Clin Chem 52:819-26. 2006
    ..We also explored the prognostic accuracy of maternal serum S100B for IVH in the newborn...
  12. doi request reprint New markers of neonatal neurology
    Diego Gazzolo
    Department of Pediatrics and Neuroscience, G Gaslini Children s Hospital University of Genoa, Genoa, Italy
    J Matern Fetal Neonatal Med 22:57-61. 2009
    ....
  13. ncbi request reprint Circulating biochemical markers of brain damage in infants complicated by ischemia reperfusion injury
    Diego Gazzolo
    Department of Pediatrics, Neuroscience and Cardiovascular Surgery, G Gaslini Children s Hospital University of Genoa, Genoa, Italy
    Cardiovasc Hematol Agents Med Chem 7:108-26. 2009
    ....
  14. pmc Diagnostic accuracy of S100B urinary testing at birth in full-term asphyxiated newborns to predict neonatal death
    Diego Gazzolo
    Department of Obstetrics, G Gaslini Children s Hospital University of Genoa, Genoa, Italy
    PLoS ONE 4:e4298. 2009
    ..We studied the possibility that urine S100B measurement may identify which PA-affected infants are at risk of early postnatal death...
  15. ncbi request reprint Kangaroo care improves post-extubation cardiorespiratory parameters in infants after open heart surgery
    D Gazzolo
    Department of Neonatology, G Gaslini Children s Hospital, Genoa, Italy
    Acta Paediatr 89:728-9. 2000
    ..8 vs 12 +/- 1.2 mmHg) significantly decreased (p <0.05 for all), while oxygen saturation (78 +/- 6 vs 74 5 mmHg) and transcutaneous oxygen pressure increased (42 +/- 2 vs 38 +/- 3 mmHg) (p < 0.05 for all)...
  16. ncbi request reprint Circulating adrenomedullin is increased in preterm newborns developing intraventricular hemorrhage
    D Gazzolo
    Department of Neonatology, G Gaslini University Hospital, Genoa, Italy
    Pediatr Res 50:544-7. 2001
    ..This study suggests that adrenomedullin blood concentration might be a promising tool for identifying preterm infants at risk of IVH immediately after birth, when imaging assessment and clinical symptoms of hemorrhage are still silent...
  17. ncbi request reprint S100B blood levels correlate with rewarming time and cerebral Doppler in pediatric open heart surgery
    Diego Gazzolo
    Department of Pediatrics, Giannina Gaslini Children s University Hospital, 1 16147 Genoa, Italy
    J Card Surg 17:279-84. 2002
    ..Blood S100B levels are emerging as a marker of brain distress, and could offer a reliable monitoring tool at different times during and after open heart surgery...
  18. ncbi request reprint Circulating S100beta protein is increased in intrauterine growth-retarded fetuses
    Diego Gazzolo
    Department of Pediatrics, Giannina Gaslini Children s University Hospital, Genoa, Italy
    Pediatr Res 51:215-9. 2002
    ..This study provides evidence that circulating S100beta protein is increased in IUGR fetuses and correlates with cerebral hemodynamics, suggesting that it may represent an index of cerebral cell damage in the perinatal period...
  19. ncbi request reprint Elevated S100B protein as an early indicator of intracranial haemorrhage in infants subjected to extracorporeal membrane oxygenation
    D Gazzolo
    Department of Neonatology, G Gaslini Children s University Hospital, Genoa, Italy
    Acta Paediatr 91:218-21. 2002
    ..0 microg/L, 4.12 microg/L, respectively). MCA PI values in the ICH group were also significantly higher, but only 24 h before any ultrasound pattern of bleeding was detected (ICH: 2.31 +/- 0.22 vs control: 1.81 +/- 0.24) (p < 0.05)...
  20. ncbi request reprint S100B protein is increased in asphyxiated term infants developing intraventricular hemorrhage
    Diego Gazzolo
    Department of Neonatology, G Gaslini Children s University Hospital, Genoa, Italy
    Crit Care Med 30:1356-60. 2002
    ..To establish whether S100B protein may be useful in the early detection of intraventricular hemorrhage in asphyxiated term infants...
  21. ncbi request reprint Adrenomedullin blood concentrations in infants subjected to cardiopulmonary bypass: correlation with monitoring parameters and prediction of poor neurological outcome
    Pasquale Florio
    Department of Pediatrics, Obstetrics, and Reproductive Medicine, University of Siena, Siena, Italy
    Clin Chem 54:202-6. 2008
    ..We evaluated whether cardiopulmonary bypass (CPB) affects cerebrovascular resistance and plasma concentrations of adrenomedullin (AM), a vasoactive peptide regulating cerebral blood flow...
  22. ncbi request reprint Perioperative activin A concentrations as a predictive marker of neurologic abnormalities in children after open heart surgery
    Pasquale Florio
    Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Siena, Italy
    Clin Chem 53:982-5. 2007
    ....
  23. ncbi request reprint Urinary S100B protein concentrations are increased in intrauterine growth-retarded newborns
    Pasquale Florio
    Department of Pediatrics, Obstetrics, and Reproductive Medicine, University of Siena, Siena, Italy
    Pediatrics 118:e747-54. 2006
    ..Intrauterine growth retardation is one of the major causes of perinatal mortality and morbidity. To date, there are no reliable methods to detect brain damage in these patients...
  24. ncbi request reprint S100B protein levels in saliva: correlation with gestational age in normal term and preterm newborns
    Diego Gazzolo
    Department of Pediatrics, Service of Epidemiology and Biostatistics Scientific Direction, Giannina Gaslini Children s University Hospital, Genoa, Italy
    Clin Biochem 38:229-33. 2005
    ..It has been suggested to act as a cytokine with neurotrophic effects at physiological concentrations...
  25. ncbi request reprint Near Infrared Spectroscopy in healthy preterm and term newborns: correlation with gestational age and standard monitoring parameters
    Lucia Gabriella Tina
    Department of Maternal, Fetal and Neonatal Medicine, G Garibaldi Hospital, Catania, Italy
    Curr Neurovasc Res 6:148-54. 2009
    ..NIRS reference curve could be particularly useful in sick newborns brain monitoring...
  26. ncbi request reprint Maternal glucocorticoid supplementation and S100B protein concentrations in cord blood and urine of preterm infants
    Diego Gazzolo
    Department of Pediatrics and Obstetrics, G Gaslini Children s University Hospital, I 16167 Genoa, Italy
    Clin Chem 49:1215-8. 2003
  27. doi request reprint Antenatal glucocorticoid treatment affects preterm infants' S100B urine concentration in a dose-dependent manner
    Andrea Sannia
    Dept of Neonatology Obstetrics and Neuroscience, G Gaslini Children s University Hospital, Genoa, Italy
    Clin Chim Acta 411:1539-41. 2010
    ..We investigated whether antenatal GC administration affects CNS function in a dose-dependent manner by measuring urine concentrations of a well-established brain damage marker, S100B...
  28. doi request reprint Biomarkers of brain damage in preterm infants
    Francesco M Risso
    Department of Neonatology, G Gaslini Children s University Hospital, Genoa, Italy
    J Matern Fetal Neonatal Med 25:101-4. 2012
    ..This could be especially useful in perinatal medicine that requires even more non-invasive techniques in order to fulfill the minimal handling in diagnostic and therapeutic strategy performance...
  29. doi request reprint Perinatal asphyxia: kidney failure does not affect S100B urine concentrations
    Francesco M Risso
    Department of Neonatology Obstetrics and Neuroscience, G Gaslini Children s University Hospital, Genoa, Italy
    Clin Chim Acta 413:150-3. 2012
    ....
  30. doi request reprint S100B protein maternal and fetal bloodstreams gradient in healthy and small for gestational age pregnancies
    Andrea Sannia
    Dept of Neonatology Obstetrics and Neuroscience, G Gaslini Children s University Hospital, Genoa, Italy
    Clin Chim Acta 412:1337-40. 2011
    ..The present study investigates in healthy and small gestational age fetuses (SGA) whether S100B concentrations differ among fetal and maternal bloodstreams...
  31. ncbi request reprint Amniotic fluid levels of S100B protein in normal and trisomy-21 foetuses
    Diego Gazzolo
    Department of Paediatrics, Giannina Gaslini Children s University Hospital, I 16147 Genoa, Italy
    Clin Chim Acta 330:131-3. 2003
    ..The present case-control study was aimed at investigating whether overproduction of S100B protein is detectable in the amniotic fluid of foetuses with trisomy-21...
  32. ncbi request reprint Activin A in asphyxiated full-term newborns with hypoxic ischemic encephalopathy
    Pasquale Florio
    Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Siena, Italy
    Front Biosci (Elite Ed) 2:36-42. 2010
    ..66 ng/L activin-A achieved a sensitivity of 93.33 per cent and a specificity of 96.63 per cent, respectively, as HIE diagnostic test. These findings show that activin A increased in AFTNs with HIE before the appearance of related signs...
  33. doi request reprint S100B urine concentrations in late preterm infants are gestational age and gender dependent
    Andrea Sannia
    Dept Critical Care and Perinatal Medicine G Gaslini Children s Hospital, Genoa, Italy
    Clin Chim Acta 417:31-4. 2013
    ..Therefore, we aimed at offering a reference curve in LP period of a well-established neurotrophic and brain damage marker namely S100B protein...
  34. doi request reprint First intention high-frequency oscillatory and conventional mechanical ventilation in premature infants without antenatal glucocorticoid prophylaxis
    Vincenzo Salvo
    Department of Maternal, Fetal and Neonatal Medicine, University of Messina, Messina, Italy
    Pediatr Crit Care Med 13:72-9. 2012
    ....
  35. ncbi request reprint S100B protein and near infrared spectroscopy in preterm and term newborns
    Lucia Gabriella Tina
    Department of Maternal, Fetal and Neonatal Medicine, G Garibaldi Hospital, Catania, Italy
    Front Biosci (Elite Ed) 2:159-64. 2010
    ..77; FTOE: r=-0.69; P less than 0.01) has been found. The present study shows that NIRS parameters and S100B protein correlation may be of help in brain function monitoring...
  36. doi request reprint Urine S100 BB and A1B dimers are valuable predictors of adverse outcome in full-term asphyxiated infants
    Francesco M Risso
    Department of Neonatology, G Gaslini Children s University Hospital, Genoa, Italy
    Acta Paediatr 102:e467-72. 2013
    ..To investigate whether S100A1B and BB dimers are predictors of early perinatal death in newborns with perinatal asphyxia (PA)...
  37. ncbi request reprint Cerebrospinal fluid activin a measurement in asphyxiated full-term newborns predicts hypoxic ischemic encephalopathy
    Pasquale Florio
    Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Siena, Italy
    Clin Chem 50:2386-9. 2004
  38. ncbi request reprint High urinary concentrations of activin A in asphyxiated full-term newborns with moderate or severe hypoxic ischemic encephalopathy
    Pasquale Florio
    Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Tuscany, Italy
    Clin Chem 53:520-2. 2007
    ..We measured activin A in urine collected immediately after birth in asphyxiated full-term newborns, and assessed the ability of the measurements to predict the occurrence of perinatal encephalopathy...
  39. doi request reprint Human milk and formulae: neurotrophic and new biological factors
    Laura D Serpero
    Department of Neurology, Ophthalmology and Genetics, Genoa University, Genoa, Italy
    Early Hum Dev 88:S9-12. 2012
    ....
  40. ncbi request reprint Levels of S100B protein are higher in mature human milk than in colostrum and milk-formulae milks
    Diego Gazzolo
    Department of Obstetrics and Pediatrics, Giannina Gaslini Children s University Hospital, I 16147 Genoa, Italy
    Clin Nutr 23:23-6. 2004
    ..The present study investigates the concentrations of this protein in colostrum, human milk at different levels of maturation and in milk-formulae...
  41. ncbi request reprint Pediatric concentrations of S100B protein in blood: age- and sex-related changes
    Diego Gazzolo
    Department of Pediatrics, Giannina Gaslini Children s University Hospital, I 16147 Genoa, Italy
    Clin Chem 49:967-70. 2003
  42. doi request reprint N-SIPPV versus bi-level N-CPAP for early treatment of respiratory distress syndrome in preterm infants
    Alberto Ricotti
    Neonatal Intensive Care Unit, C Arrigo Children s Hospital, Alessandria, Italy
    J Matern Fetal Neonatal Med 26:1346-51. 2013
    ..Further randomized studies to assess the advantages and the efficacy of different methods of NIV for the treatment of the RDS are needed. ..
  43. doi request reprint Antenatal maternal antidepressants drugs affect Activin A concentrations in maternal blood, in amniotic fluid and in fetal cord blood
    Valentina Bellissima
    Department of Maternal, Fetal and Neonatal Medicine, Cesare Arrigo Children s Hospital, Alessandria, Italy
    J Matern Fetal Neonatal Med 24:31-4. 2011
    ..We investigated, in pregnant women and in fetal biological fluids whether the concentrations of a brain protein, Activin A, changed in association with the use of selective serotonin re-uptake inhibitors (SSRI)...
  44. ncbi request reprint Increased S100B in cerebrospinal fluid of infants with bacterial meningitis: relationship to brain damage and routine cerebrospinal fluid findings
    Diego Gazzolo
    Department of Pediatrics and Obstetrics and Gynecology, Giannina Gaslini Children s University Hospital, Genoa, Italy
    Clin Chem 50:941-4. 2004
  45. ncbi request reprint S100B protein concentrations in amniotic fluid are higher in monoamniotic than in diamniotic twins and singleton pregnancies
    Diego Gazzolo
    Department of Pediatrics, Giannina Gaslini Children s University Hospital, I 16147 Genoa, Italy
    Clin Chem 49:997-9. 2003
  46. doi request reprint S100B Protein concentration in milk-formulas for preterm and term infants. Correlation with industrial preparation procedures
    Francesco Nigro
    Department of Maternal, Fetal and Neonatal Health, G Garibaldi Hospital, Catania, Italy
    Mol Nutr Food Res 52:609-13. 2008
    ..New feeding strategies in preterm and term infants are therefore warranted in order to preserve S100B protein during industrial preparation...
  47. ncbi request reprint Activin A in brain injury
    Pasquale Florio
    Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Siena, Italy
    Adv Clin Chem 43:117-30. 2007
    ..This approach may also facilitate the diagnosis of subclinical lesions at stages when monitoring procedures are unable to detect brain lesion and furthermore establish a prognosis...
  48. ncbi request reprint Human milk contains S100B protein
    Diego Gazzolo
    Department of Pediatrics, Giannina Gaslini Children s University Hospital, I 16147 Genoa, Italy
    Biochim Biophys Acta 1619:209-12. 2003
    ..This finding could be related to a possible trophic role, which has been hypothesized for the protein...
  49. doi request reprint Elevated Activin A urine levels are predictors of intraventricular haemorrhage in preterm newborns
    Andrea Sannia
    Department of Critical Care and Perinatal Medicine, G Gaslini Children s Hospital, Genoa, Italy
    Acta Paediatr 102:e449-54. 2013
    ..We evaluated the usefulness of urine Activin A concentrations for the early detection of perinatal IVH...
  50. ncbi request reprint High maternal and fetal plasma urocortin levels in pregnancies complicated by hypertension
    Pasquale Florio
    Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Siena, Italy
    J Hypertens 24:1831-40. 2006
    ....
  51. ncbi request reprint S100 beta protein is increased in fetuses with neural tube defect
    Emanuela Marinoni
    Centre for Scientific Research, San Pietro Hospital, Fatebenefratelli, Rome, Italy
    Front Biosci (Elite Ed) 2:47-51. 2010
    ..This study indicates that NTD is associated with increased serum concentration of S100B in fetuses and mothers. Moreover, it gives information on S100B levels in the fetal circulation in early-mid gestation...
  52. ncbi request reprint Ontogenetic localization and distribution of S-100beta protein in human placental tissues
    Emanuela Marinoni
    Laboratory of Perinatal Medicine and Molecular Biology, Second Institute of Obstetrics and Gynecology, University of Rome La Sapienza, Rome, Italy
    Obstet Gynecol 99:1093-9. 2002
    ..To investigate whether S-100beta, a brain-specific protein found in amniotic fluid and fetal circulation, is present in fetoplacental tissues throughout gestation...
  53. ncbi request reprint Adrenomedullin increases in term asphyxiated newborns developing intraventricular hemorrhage
    Romolo Di Iorio
    Laboratory of Perinatal Medicine and Molecular Biology, Institute of Gynecology, Perinatology and Child Health, University La Sapienza, Rome, Italy
    Clin Biochem 37:1112-6. 2004
    ..The aim of this study was to investigate whether circulating AM was increased in infants with prenatal asphyxia who developed intraventricular hemorrhage (IVH)...
  54. doi request reprint Italia-Netherland PhD Program: the I.O. PhD Research Program
    Valentina Bellissima
    Department of Maternal, Fetal and Neonatal Medicine, C Arrigo Children s Hospital, Alessandria, Italy
    J Matern Fetal Neonatal Med 24:111-3. 2011
    ..Five manuscripts have been published and/or submitted to international Journals regarding pneumology, perinatal asphyxia and teratology, whilst about 60-70% of data regarding clinical studies have already been collected...
  55. doi request reprint Metabolomic analysis of bronchoalveolar lavage fluid in preterm infants complicated by respiratory distress syndrome: preliminary results
    Adele Fabiano
    Department of Maternal, Fetal and Neonatal Medicine, CasilinoHospital, Rome, Italy
    J Matern Fetal Neonatal Med 24:55-8. 2011
    ..The aim of the present preliminary study was to analyze metabolic profiles in preterm infants complicated by respiratory distress syndrome (RDS) trough bronchoalveolar lavage fluid (BALF) measurement...
  56. ncbi request reprint Reference values of blood cell counts in the first days of life
    Giovanni Melioli
    Clinical Pathology Laboratories, G Gaslini Children s Hospital, Genoa, Italy
    Front Biosci (Elite Ed) 3:871-8. 2011
    ..This study shares updated reference values for hematological parameters in the early phases after birth and offers additional support for improving the management of sick infants...
  57. ncbi request reprint Lack of effect of dietary nucleotide supplementation on erythrocyte 2,3-diphosphoglycerate concentration. A study on preterm neonates
    Fabio Scopesi
    Department of Neonatal Care, Genoa University, G Gaslini Institute, Genoa, Italy
    J Matern Fetal Neonatal Med 19:343-6. 2006
    ..Recently we demonstrated an increased 2,3-diphosphoglycerate (2,3-DPG) erythrocyte concentration in rat pups subjected to nucleotide-enriched artificial feeding...
  58. doi request reprint Preterm and term newborn: primary investigations
    Francesco M Risso
    NICU G Gaslini Children s Hospital, Genoa, Italy
    J Matern Fetal Neonatal Med 25:70-2. 2012
    ....
  59. doi request reprint The S100B protein in biological fluids: more than a lifelong biomarker of brain distress
    Fabrizio Michetti
    Institute of Anatomy and Cell Biology, Universita Cattolica Sacro Cuore, Roma, Italy
    J Neurochem 120:644-59. 2012
    ..This possibility makes this protein a candidate not only for a biomarker but also for a potential therapeutic target...
  60. ncbi request reprint [Markers of brain injury in non-invasive biological fluids]
    L Moresco
    Department of Fetal, Maternal and Neonatal Medicine, C Armgo, Alessandria, Italy
    Minerva Pediatr 62:141-3. 2010
    ..The present article is aimed at investigating the role of dosage biochemical markers in non-invasive biological fluids such as S100B, a calcium binding protein, activin A, a protein expressed in Central nervous System (CNS)...
  61. ncbi request reprint S100B protein cord blood levels and development of fetal behavioral states: a study in normal and small-for-dates fetuses
    D Gazzolo
    Department of Pediatrics, Giannina Gaslini Children s University Hospital, Genoa, Italy
    J Matern Fetal Neonatal Med 11:378-84. 2002
    ..We aimed to determine whether S100B protein levels in cord blood and the development of fetal behavioral states were altered and interrelated in small-for-dates (SFD) fetuses...
  62. pmc Perinatal S100B Protein Assessment in Human Unconventional Biological Fluids: A Minireview and New Perspectives
    Diego Gazzolo
    Department of Maternal, Fetal and Neonatal Medicine, C Arrigo Children s Hospital, Alessandria, Italy
    Cardiovasc Psychiatry Neurol 2010:703563. 2010
    ..Results offer new possibilities for the use of S100B in perinatal medicine as a key-protein for the investigations focusing on central nervous system development and damage...
  63. doi request reprint Isoprostanes in dystrophinopathy: Evidence of increased oxidative stress
    Salvatore Grosso
    Department of Pediatrics, Obstetrics and Reproductive Medicine, Viale Mario Bracci 36, 53100 Siena, Italy
    Brain Dev 30:391-5. 2008
    ..The condition of oxidative stress might act as an adjunctive cause of extra-muscular cell damage to which these patients are exposed for their entire life...
  64. ncbi request reprint S100B protein in biological fluids: a tool for perinatal medicine
    Fabrizio Michetti
    Institute of Anatomy, Catholic University, Largo Francesco Vito 1, I 00168 Rome, Italy
    Clin Chem 48:2097-104. 2002
    ..Finally, because of the neurotrophic role putatively played by S100B, its measurement in biological fluids at pre-/perinatal ages makes it a candidate for the laboratory evaluation of brain maturation...
  65. doi request reprint Maternal dietary habits and mycotoxin occurrence in human mature milk
    Fabio Galvano
    STAFA Department, Mediterranean University of Reggio Calabria, Reggio Calabria, Italy
    Mol Nutr Food Res 52:496-501. 2008
    ..The findings support the possibility of dietary recommendations to woman, during pregnancy and lactation, aimed to tentatively reduce the OTA contamination of human milk...
  66. ncbi request reprint Maternal nitric oxide supplementation decreases cord blood S100B in intrauterine growth-retarded fetuses
    Diego Gazzolo
    Clin Chem 48:647-50. 2002
  67. ncbi request reprint S100A1B and S100BB urine levels in preterm and term healthy newborns
    Diego Gazzolo
    Clin Chim Acta 384:186-7. 2007
  68. ncbi request reprint Systemic endotoxin administration results in increased S100B protein blood levels and periventricular brain white matter injury in the preterm fetal sheep
    Yves Garnier
    Department of Obstetrics and Gynecology, University Hospitals of Aachen and Cologne, Kerpenerstrasse 62, 50924 Cologne, Germany
    Eur J Obstet Gynecol Reprod Biol 124:15-22. 2006
    ..The aim of the present study was to clarify, whether intravenous application of endotoxin results in neuropathological findings and increased blood levels of the S100B protein, which is a consolidated marker of brain injury...
  69. ncbi request reprint Prenatal stress reduces S100B in the neonatal rat hippocampus
    Daniel L A van den Hove
    Department of Pediatrics, Faculty of Medicine, Maastricht University, Maastricht, The Netherlands
    Neuroreport 17:1077-80. 2006
    ..In conclusion, the observed reduction in neonatal hippocampal S100B levels, as a consequence of prenatal stress, may be involved in affecting postnatal brain development...
  70. ncbi request reprint S100B protein blood concentrations in pulmonary and systemic circulation: correlations with oxygenation status and sampling modalities
    Gian Paolo Ussia
    Clin Chim Acta 380:243-4. 2007
  71. ncbi request reprint S100B testing in pregnancy
    Fabrizio Michetti
    Institute of Anatomy and Cell Biology, Catholic University, Largo Francesco Vito 1, I 00168, Rome, Italy
    Clin Chim Acta 335:1-7. 2003
    ..It appears also to be relevant that a neurotrophic role has been hypothesized for the protein, which in fact exhibits in amniotic fluid, in cord blood and in placenta patterns of concentration related to the gestational age...
  72. ncbi request reprint Acute hypoxia increases S100beta protein in association with blood flow redistribution away from peripheral circulations in fetal sheep
    Dino A Giussani
    Department of Physiology, University of Cambridge, Cambridge, CB2 3EG, United Kingdom
    Pediatr Res 58:179-84. 2005
    ..These findings open up a new role for changes in fetal S100beta concentrations as a possible early marker of fetal hypoxia with associated acidemia in perinatal medicine...
  73. ncbi request reprint Effects of temperature on pre-analytical stability of S100B protein concentrations in urine of healthy full-term infants
    Diego Gazzolo
    Clin Chim Acta 350:231-2. 2004
  74. ncbi request reprint Amniotic fluid S100B protein in mid-gestation and intrauterine fetal death
    Pasquale Florio
    Department of Paediatrics, Obstetrics, and Reproductive Medicine, University of Siena, Policlinico Le Scotte, Viale Bracci, 53100 Siena, Italy
    Lancet 364:270-2. 2004
    ..000 MoM [1.062-1.121]). Sensitivity, specificity, and positive and negative predictive values of S100B as a diagnostic test were 100%, suggesting that measurement of this protein at amniocentesis could be useful to identify at-risk women...
  75. ncbi request reprint Lowering the dose of antenatal steroids: the effects of a single course of betamethasone on somatic growth and brain cell proliferation in the rat
    Matteo Bruschettini
    Division of Neuroscience, Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience EURON, Maastricht, The Netherlands
    Am J Obstet Gynecol 194:1341-6. 2006
    ..In summary, we show for the first time that a lower dose (equivalent to 6 mg) induces fewer and less severe effects on somatic growth, whereas it does not affect cell proliferation within the brain...
  76. ncbi request reprint A single course of antenatal betamethasone reduces neurotrophic factor S100B concentration in the hippocampus and serum in the neonatal rat
    Matteo Bruschettini
    Department of Psychiatry and Neuropsychology, Division of Cellular Neuroscience, Faculty of Medicine, University of Maastricht, Maastricht, The Netherlands
    Brain Res Dev Brain Res 159:113-8. 2005
    ..This suggests that lowering the dose of antenatal betamethasone may be less detrimental for brain maturation and therefore we reiterate the need for clinical trials with a low dose regimen...