Screening for asymptomatic coronary artery disease can reduce cardiovascular mortality and morbidity in type 2 diabetic patientsCarmine Gazzaruso
Clinical Institute Beato Matteo ICBM, Hospital Group San Donato, Vigevano, Pavia, Italy
Intern Emerg Med 7:257-66. 2012
..This may be due to specific diagnostic and therapeutic interventions in diabetic patients with proven CAD at screening...
- Lipoprotein(a) and homocysteine as genetic risk factors for vascular and neuropathic diabetic foot in type 2 diabetes mellitus
Carmine Gazzaruso
Internal Medicine, Diabetes, Endocrine Metabolic Diseases and Cardiovascular Prevention Unit and the Centre for Applied Clinical Research Ce R C A, Clinical Institute Beato Matteo, Corso Pavia 84, 27029, Vigevano, Italy
Endocrine 41:89-95. 2012
..Our study has shown for the first time that high Lp(a) and Hcy levels are associated with the development of VDF, while low Lp(a) levels appear to be associated with delayed wound healing in patients with neuropathic foot ulcerations...
- Erectile dysfunction can improve the effectiveness of the current guidelines for the screening for asymptomatic coronary artery disease in diabetes
Carmine Gazzaruso
Internal Medicine, Diabetes, Endocrine Metabolic Diseases and Cardiovascular Prevention Unit and the Centre for Applied Clinical Research Ce R C A, Clinical Institute Beato Matteo, Corso Pavia 84, Vigevano, 27029, Pavia, Italy
Endocrine 40:273-9. 2011
..This study first shows that ED can improve the effectiveness in discriminating diabetic men to screen for asymptomatic CAD, when it is added to the list of RFs of the current screening guidelines...
Erectile dysfunction and coronary artery disease in patients with diabetesCarmine Gazzaruso
Internal Medicine, Vascular and Endocrine Metabolic Diseases Unit and Centre for Applied Clinical Research Ce R C A Clinical Institute Beato Matteo ICBM, Hospital Group San Donato, Vigevano, Italy
Curr Diabetes Rev 7:143-7. 2011
..At last, the review reports current guidelines and recent data available in the literature on the treatment of ED in patients with and without CAD and on the prevention of CAD in patients with ED...
- Association of the metabolic syndrome and insulin resistance with silent myocardial ischemia in patients with type 2 diabetes mellitus
Carmine Gazzaruso
IRCCS Maugeri Foundation Hospital, Pavia, Italy
Am J Cardiol 97:236-9. 2006
..Other studies are needed to establish whether metabolic syndrome and HOMA are reliable markers to identify diabetic patients for additional screening for silent CAD...
- Relationship between erectile dysfunction and silent myocardial ischemia in apparently uncomplicated type 2 diabetic patients
Carmine Gazzaruso
Internal Medicine Unit, IRCCS Maugeri Foundation Hospital, Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy
Circulation 110:22-6. 2004
..In diabetic patients, CAD is often silent. Among diabetic patients with silent CAD, the prevalence of ED has never been evaluated. We investigated whether ED is associated with asymptomatic CAD in type 2 diabetic patients...
- Improvement of blood glucose control and insulin sensitivity during a long-term (60 weeks) randomized study with amino acid dietary supplements in elderly subjects with type 2 diabetes mellitus
Sebastiano B Solerte
Geriatric Clinic, Department of Internal Medicine, University of Pavia, Pavia, Italy
Am J Cardiol 101:82E-88E. 2008
..This effect was consistent during the long-term observation period of 60 weeks and was also present after the crossover from AAs to placebo...
- Nutritional supplements with oral amino acid mixtures increases whole-body lean mass and insulin sensitivity in elderly subjects with sarcopenia
Sebastiano B Solerte
Geriatric Clinic, Department of Internal Medicine, University of Pavia, Pavia, Italy
Am J Cardiol 101:69E-77E. 2008
..The improvement in the amount of whole-body lean mass could be linked to increased insulin sensitivity and anabolic conditions related to IGF-1 availability...
- Erectile dysfunction as a predictor of cardiovascular events and death in diabetic patients with angiographically proven asymptomatic coronary artery disease: a potential protective role for statins and 5-phosphodiesterase inhibitors
Carmine Gazzaruso
Cardio Metabolic Unit and the Centre for Applied Clinical Research Ce R C A Clinical Institute Beato Matteo, Hospital Group San Donato, Vigevano, Italy
J Am Coll Cardiol 51:2040-4. 2008
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- Decreased release of the angiogenic peptide vascular endothelial growth factor in Alzheimer's disease: recovering effect with insulin and DHEA sulfate
Sebastiano Bruno Solerte
Department of Internal Medicine and Geriatrics, University of Pavia, Pavia, Piazza Borromeo 2, IT 27100, Italy
Dement Geriatr Cogn Disord 19:1-10. 2005
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- Metabolic effects of orally administered amino acid mixture in elderly subjects with poorly controlled type 2 diabetes mellitus
Sebastiano B Solerte
Department of Internal Medicine, Geriatric Clinic, University of Pavia, Pavia, Italy
Am J Cardiol 93:23A-29A. 2004
..We suggest that increased amino acid availability for skeletal muscle function and strength could ameliorate metabolic control and insulin sensitivity in elderly patients with poorly controlled type 2 diabetes...
- Assessment of asymptomatic coronary artery disease in apparently uncomplicated type 2 diabetic patients: a role for lipoprotein(a) and apolipoprotein(a) polymorphism
Carmine Gazzaruso
Internal Medicine Unit, Diabetes Center, IRCCS Maugeri Foundation Hospital, Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy
Diabetes Care 25:1418-24. 2002
..We investigated the association of Lp(a) and apo(a) polymorphism with angiographically documented asymptomatic CAD in type 2 diabetic patients without evident complications...
