Marie Soleil Gauthier

Summary

Publications

  1. doi request reprint Adipose tissue inflammation and insulin resistance: all obese humans are not created equal
    Marie Soleil Gauthier
    Diabetes and Metabolism Unit, Department of Medicine, Section of Endocrinology, Boston University Medical Center, Boston, MA 02118, U S A
    Biochem J 430:e1-4. 2010
  2. pmc Decreased AMP-activated protein kinase activity is associated with increased inflammation in visceral adipose tissue and with whole-body insulin resistance in morbidly obese humans
    Marie Soleil Gauthier
    Diabetes and Metabolism Unit, Section of Endocrinology, Boston University School of Medicine, Boston, MA 02118, USA
    Biochem Biophys Res Commun 404:382-7. 2011
  3. pmc Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue
    X Julia Xu
    Diabetes and Metabolism Unit, Section of Endocrinology, Boston University School of Medicine, Boston, MA 02118, USA
    J Lipid Res 53:792-801. 2012
  4. pmc A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells
    Lauren E Nelson
    Endocrinology, Diabetes, and Nutrition Section, Department of Medicine, Boston University School of Medicine, Massachusetts, USA
    Am J Physiol Cell Physiol 303:C4-C13. 2012
  5. pmc Acute exercise activates AMPK and eNOS in the mouse aorta
    Jose M Cacicedo
    Diabetes and Metabolism Research Unit, Department of Medicine and Section of Endocrinology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Physiol Heart Circ Physiol 301:H1255-65. 2011
  6. pmc Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells
    Gabriela Suchankova
    Department of Medicine, Section of Endocrinology, Boston Medical Center, Boston, MA 02118, USA
    Biochem Biophys Res Commun 378:836-41. 2009
  7. doi request reprint Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individuals
    Marie Soleil Gauthier
    Institut de Recherches Cliniques de Montréal M S G, J R P, M E L, B C, R R L, Montreal, QC H2W 1R7, Canada Montreal Diabetes Research Center at the Centre de Recherche du Centre Hospitalier de l Université de Montréal CRCHUM M S G, M E L, R S, S R M M, M P, R R L, Montreal, QC H2X 0A9, Canada McGill University and Centre d Innovation Génome Québec R S, Montreal, QC H3A 0G1, Canada Molecular Nutrition Unit at the CRCHUM S R M M, M P, Montreal, QC H2X 0A9, Canada Diabetes and Metabolism Research Unit N B R, and Department of Medicine and Section of Endocrinology N B R, Boston University School of Medicine, Boston, Massachusetts 02118 Departments of Biochemistry B C, M P and Nutrition M E L, M P, R R L, Faculty of Medicine, Universite de Montreal, Montreal, QC H3C 3J7, Canada
    J Clin Endocrinol Metab 99:E2518-28. 2014
  8. pmc AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance
    Marie Soleil Gauthier
    Diabetes and Metabolism Unit, Department of Medicine Section of Endocrinology, Boston University Medical Center, Boston, Massachusetts 02118, USA
    J Biol Chem 283:16514-24. 2008

Collaborators

Detail Information

Publications8

  1. doi request reprint Adipose tissue inflammation and insulin resistance: all obese humans are not created equal
    Marie Soleil Gauthier
    Diabetes and Metabolism Unit, Department of Medicine, Section of Endocrinology, Boston University Medical Center, Boston, MA 02118, U S A
    Biochem J 430:e1-4. 2010
    ..Further studies will be required for this purpose, as well as to identify the pathogenetic factors that determine whether or not adipose tissue of an obese individual becomes inflamed...
  2. pmc Decreased AMP-activated protein kinase activity is associated with increased inflammation in visceral adipose tissue and with whole-body insulin resistance in morbidly obese humans
    Marie Soleil Gauthier
    Diabetes and Metabolism Unit, Section of Endocrinology, Boston University School of Medicine, Boston, MA 02118, USA
    Biochem Biophys Res Commun 404:382-7. 2011
    ..Whether adipose tissue AMPK dysregulation is a causal factor for the development of the inflammation and insulin resistance remains to be determined...
  3. pmc Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue
    X Julia Xu
    Diabetes and Metabolism Unit, Section of Endocrinology, Boston University School of Medicine, Boston, MA 02118, USA
    J Lipid Res 53:792-801. 2012
    ..However, most changes in gene expression appear to be depot-specific...
  4. pmc A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells
    Lauren E Nelson
    Endocrinology, Diabetes, and Nutrition Section, Department of Medicine, Boston University School of Medicine, Massachusetts, USA
    Am J Physiol Cell Physiol 303:C4-C13. 2012
    ..Collectively, these findings suggest the existence of a novel reciprocal interaction between AMPK/SIRT1 and p53 that may have implications for the pathogenesis and treatment of metabolic diseases...
  5. pmc Acute exercise activates AMPK and eNOS in the mouse aorta
    Jose M Cacicedo
    Diabetes and Metabolism Research Unit, Department of Medicine and Section of Endocrinology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Physiol Heart Circ Physiol 301:H1255-65. 2011
    ..The results also suggest that AMPK likely is the principal activator of eNOS in this setting and that its own activation may be mediated by both SIRT1-LKB1 and CaMKKβ...
  6. pmc Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells
    Gabriela Suchankova
    Department of Medicine, Section of Endocrinology, Boston Medical Center, Boston, MA 02118, USA
    Biochem Biophys Res Commun 378:836-41. 2009
    ..Collectively, these findings raise the possibility that glucose-induced changes in AMPK are linked to alterations in SIRT1 abundance and activity and possibly cellular redox state...
  7. doi request reprint Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individuals
    Marie Soleil Gauthier
    Institut de Recherches Cliniques de Montréal M S G, J R P, M E L, B C, R R L, Montreal, QC H2W 1R7, Canada Montreal Diabetes Research Center at the Centre de Recherche du Centre Hospitalier de l Université de Montréal CRCHUM M S G, M E L, R S, S R M M, M P, R R L, Montreal, QC H2X 0A9, Canada McGill University and Centre d Innovation Génome Québec R S, Montreal, QC H3A 0G1, Canada Molecular Nutrition Unit at the CRCHUM S R M M, M P, Montreal, QC H2X 0A9, Canada Diabetes and Metabolism Research Unit N B R, and Department of Medicine and Section of Endocrinology N B R, Boston University School of Medicine, Boston, Massachusetts 02118 Departments of Biochemistry B C, M P and Nutrition M E L, M P, R R L, Faculty of Medicine, Universite de Montreal, Montreal, QC H3C 3J7, Canada
    J Clin Endocrinol Metab 99:E2518-28. 2014
    ..Altered fatty-acid (FA) metabolism in sc adipose tissue (SAT) contributes to obesity-associated IR...
  8. pmc AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance
    Marie Soleil Gauthier
    Diabetes and Metabolism Unit, Department of Medicine Section of Endocrinology, Boston University Medical Center, Boston, Massachusetts 02118, USA
    J Biol Chem 283:16514-24. 2008
    ..Finally, this AMPK activation appears to restrain the energy depletion and oxidative stress caused by lipolysis...