Elaine R Garvican

Summary

Publications

  1. ncbi Chondrocytes harvested from osteochondritis dissecans cartilage are able to undergo limited in vitro chondrogenesis despite having perturbations of cell phenotype in vivo
    E R Garvican
    Musculoskeletal Research Group, The University of Liverpool Veterinary Teaching Hospital, Leahurst, Neston, Wirral, United Kingdom
    J Orthop Res 26:1133-40. 2008
  2. ncbi MMP-mediated collagen breakdown induced by activated protein C in equine cartilage is reduced by corticosteroids
    Elaine R Garvican
    Musculoskeletal Research Group, University of Liverpool Veterinary Teaching Hospital, Leahurst, Neston, Wirral CH647TE, United Kingdom
    J Orthop Res 28:370-8. 2010
  3. ncbi Biomarkers of cartilage turnover. Part 2: Non-collagenous markers
    Elaine R Garvican
    Musculoskeletal Research Group, School of Veterinary Science, University of Liverpool, Leahurst Campus, Neston, Wirral CH64 7TE, UK
    Vet J 185:43-9. 2010
  4. ncbi Biomarkers of cartilage turnover. Part 1: Markers of collagen degradation and synthesis
    Elaine R Garvican
    Musculoskeletal Research Group, School of Veterinary Science, University of Liverpool, Leahurst Campus, Neston, Wirral CH64 7TE, UK
    Vet J 185:36-42. 2010
  5. ncbi MT3-MMP (MMP-16) is downregulated by in vitro cytokine stimulation of cartilage, but unaltered in naturally occurring equine osteoarthritis and osteochondrosis
    E R Garvican
    Musculoskeletal Research Group, University of Liverpool, Wirral, United Kingdom
    Connect Tissue Res 49:62-7. 2008

Detail Information

Publications5

  1. ncbi Chondrocytes harvested from osteochondritis dissecans cartilage are able to undergo limited in vitro chondrogenesis despite having perturbations of cell phenotype in vivo
    E R Garvican
    Musculoskeletal Research Group, The University of Liverpool Veterinary Teaching Hospital, Leahurst, Neston, Wirral, United Kingdom
    J Orthop Res 26:1133-40. 2008
    ..However, this chondrogenic differentiation potential is inferior to that seen in aged-matched normal chondrocytes...
  2. ncbi MMP-mediated collagen breakdown induced by activated protein C in equine cartilage is reduced by corticosteroids
    Elaine R Garvican
    Musculoskeletal Research Group, University of Liverpool Veterinary Teaching Hospital, Leahurst, Neston, Wirral CH647TE, United Kingdom
    J Orthop Res 28:370-8. 2010
    ..The collagenolysis associated with IL-1+APC synergy, and the inhibition of this effect by corticosteroids may involve gelatinase activation and downregulation of MMP expression, respectively...
  3. ncbi Biomarkers of cartilage turnover. Part 2: Non-collagenous markers
    Elaine R Garvican
    Musculoskeletal Research Group, School of Veterinary Science, University of Liverpool, Leahurst Campus, Neston, Wirral CH64 7TE, UK
    Vet J 185:43-9. 2010
    ..Collagen-based biomarkers were discussed in part one...
  4. ncbi Biomarkers of cartilage turnover. Part 1: Markers of collagen degradation and synthesis
    Elaine R Garvican
    Musculoskeletal Research Group, School of Veterinary Science, University of Liverpool, Leahurst Campus, Neston, Wirral CH64 7TE, UK
    Vet J 185:36-42. 2010
    ..The second part of the review considers the non-collagenous biomarkers of cartilage matrix turnover...
  5. ncbi MT3-MMP (MMP-16) is downregulated by in vitro cytokine stimulation of cartilage, but unaltered in naturally occurring equine osteoarthritis and osteochondrosis
    E R Garvican
    Musculoskeletal Research Group, University of Liverpool, Wirral, United Kingdom
    Connect Tissue Res 49:62-7. 2008
    ..The results suggest that MT3-MMP may not have a role in matrix destruction in equine cartilage diseases. Further work is required to characterize its regulation and function...