Guilherme J M Garcia

Summary

Publications

  1. pmc Biophysical model of ion transport across human respiratory epithelia allows quantification of ion permeabilities
    Guilherme J M Garcia
    Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Biophys J 104:716-26. 2013
  2. pmc A mechanochemical model for auto-regulation of lung airway surface layer volume
    Gregory Herschlag
    Department of Mathematics, University of North Carolina, Chapel Hill, NC, USA
    J Theor Biol 325:42-51. 2013
  3. doi Predicting postsurgery nasal physiology with computational modeling: current challenges and limitations
    Dennis O Frank-Ito
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Otolaryngol Head Neck Surg 151:751-9. 2014
  4. doi Computational model for the regulation of extracellular ATP and adenosine in airway epithelia
    Guilherme J M Garcia
    Department of Pharmacology, University of North Carolina, Chapel Hill, NC, 27599, USA
    Subcell Biochem 55:51-74. 2011
  5. pmc Computed nasal resistance compared with patient-reported symptoms in surgically treated nasal airway passages: a preliminary report
    Julia S Kimbell
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina School of Medicine, Chapel Hill, 27599, USA
    Am J Rhinol Allergy 26:e94-8. 2012

Collaborators

Detail Information

Publications5

  1. pmc Biophysical model of ion transport across human respiratory epithelia allows quantification of ion permeabilities
    Guilherme J M Garcia
    Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Biophys J 104:716-26. 2013
    ..By providing a method to quantify all the ion permeabilities of respiratory epithelia, the model may aid us in understanding the physiology that regulates normal airway surface hydration...
  2. pmc A mechanochemical model for auto-regulation of lung airway surface layer volume
    Gregory Herschlag
    Department of Mathematics, University of North Carolina, Chapel Hill, NC, USA
    J Theor Biol 325:42-51. 2013
    ....
  3. doi Predicting postsurgery nasal physiology with computational modeling: current challenges and limitations
    Dennis O Frank-Ito
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Otolaryngol Head Neck Surg 151:751-9. 2014
    ..This study evaluates whether computer models based on a surgeon's edits of presurgery scans can accurately predict results from computer models based on postoperative scans of the same patient using computational fluid dynamics...
  4. doi Computational model for the regulation of extracellular ATP and adenosine in airway epithelia
    Guilherme J M Garcia
    Department of Pharmacology, University of North Carolina, Chapel Hill, NC, 27599, USA
    Subcell Biochem 55:51-74. 2011
    ..This study shows that computational modeling, coupled to experimental validation, provides a powerful approach for the identification of key therapeutic targets for the improvement of airway clearance in obstructive respiratory diseases...
  5. pmc Computed nasal resistance compared with patient-reported symptoms in surgically treated nasal airway passages: a preliminary report
    Julia S Kimbell
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina School of Medicine, Chapel Hill, 27599, USA
    Am J Rhinol Allergy 26:e94-8. 2012
    ..The goal of this study was to develop methods for comparing nasal resistance computed by computational fluid dynamics (CFD) models with patient-reported symptoms of NAO using early data from a 4-year prospective study...