Guilherme J M Garcia

Summary

Publications

  1. pmc Biophysical model of ion transport across human respiratory epithelia allows quantification of ion permeabilities
    Guilherme J M Garcia
    Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Biophys J 104:716-26. 2013
  2. pmc A mechanochemical model for auto-regulation of lung airway surface layer volume
    Gregory Herschlag
    Department of Mathematics, University of North Carolina, Chapel Hill, NC, USA
    J Theor Biol 325:42-51. 2013
  3. doi Computational model for the regulation of extracellular ATP and adenosine in airway epithelia
    Guilherme J M Garcia
    Department of Pharmacology, University of North Carolina, Chapel Hill, NC, 27599, USA
    Subcell Biochem 55:51-74. 2011
  4. pmc Computed nasal resistance compared with patient-reported symptoms in surgically treated nasal airway passages: a preliminary report
    Julia S Kimbell
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina School of Medicine, Chapel Hill, 27599, USA
    Am J Rhinol Allergy 26:e94-8. 2012

Collaborators

Detail Information

Publications4

  1. pmc Biophysical model of ion transport across human respiratory epithelia allows quantification of ion permeabilities
    Guilherme J M Garcia
    Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Biophys J 104:716-26. 2013
    ..By providing a method to quantify all the ion permeabilities of respiratory epithelia, the model may aid us in understanding the physiology that regulates normal airway surface hydration...
  2. pmc A mechanochemical model for auto-regulation of lung airway surface layer volume
    Gregory Herschlag
    Department of Mathematics, University of North Carolina, Chapel Hill, NC, USA
    J Theor Biol 325:42-51. 2013
    ....
  3. doi Computational model for the regulation of extracellular ATP and adenosine in airway epithelia
    Guilherme J M Garcia
    Department of Pharmacology, University of North Carolina, Chapel Hill, NC, 27599, USA
    Subcell Biochem 55:51-74. 2011
    ..This study shows that computational modeling, coupled to experimental validation, provides a powerful approach for the identification of key therapeutic targets for the improvement of airway clearance in obstructive respiratory diseases...
  4. pmc Computed nasal resistance compared with patient-reported symptoms in surgically treated nasal airway passages: a preliminary report
    Julia S Kimbell
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina School of Medicine, Chapel Hill, 27599, USA
    Am J Rhinol Allergy 26:e94-8. 2012
    ..The goal of this study was to develop methods for comparing nasal resistance computed by computational fluid dynamics (CFD) models with patient-reported symptoms of NAO using early data from a 4-year prospective study...