Identification and prospective validation of clinically relevant chronic obstructive pulmonary disease (COPD) subtypesJudith Garcia-Aymerich
Centre for Research in Environmental Epidemiology, Doctor Aiguader 88, 08003 Barcelona, Catalonia, Spain
Thorax 66:430-7. 2011
..Chronic obstructive pulmonary disease (COPD) is increasingly considered a heterogeneous condition. It was hypothesised that COPD, as currently defined, includes different clinically relevant subtypes...
- Dietary habits of firstly admitted Spanish COPD patients
Jordi de Batlle
Centre for Research in Environmental Epidemiology CREAL, Doctor Aiguader 88, 08003 Barcelona, Spain
Respir Med 103:1904-10. 2009
..We described dietary habits in a Spanish sample of COPD patients and assessed its adequacy according to dietary recommendations, which so far have never been published...
- Physical activity and clinical and functional status in COPD
Judith Garcia-Aymerich
Centre for Research in Environmental Epidemiology, 08003 Barcelona, Catalonia, Spain
Chest 136:62-70. 2009
..Our objective was to assess the relationship between regular physical activity and the clinical and functional characteristics of COPD...
Prospective study of physical activity and risk of asthma exacerbations in older womenJudith Garcia-Aymerich
Center for research in environmental epidemiology CREAL, Doctor Aiguader 88, 08003 Barcelona, Catalonia, Spain
Am J Respir Crit Care Med 179:999-1003. 2009
..The potential role of physical activity in preventing asthma exacerbations is unknown...
- [Phenotypic characterization and course of chronic obstructive pulmonary disease in the PAC-COPD Study: design and methods]
J Garcia-Aymerich
Centre for Research in Environmental Epidemiology CREAL, Institut Municipal d Investigació Mèdica Hospital del Mar, Universitat Pompeu Fabra, CIBER de Epidemiología y Salud Pública CIBERESP, Barcelona, Espana
Arch Bronconeumol 45:4-11. 2009
..This project will enable us to reconsider the definition and classification of COPD and to better understand the factors associated with its natural history...
- Time-dependent confounding in the study of the effects of regular physical activity in chronic obstructive pulmonary disease: an application of the marginal structural model
Judith Garcia-Aymerich
Centre for Research in Environmental Epidemiology, Barcelona, Catalonia, Spain
Ann Epidemiol 18:775-83. 2008
..We sought to assess the presence of time-dependent confounding in the association between physical activity and COPD development and course by comparing risk estimates between standard statistical methods and MSMs...
- [Validation of the Yale Physical Activity Survey in chronic obstructive pulmonary disease patients]
David Donaire-González
Centre de Recerca en Epidemiologia Ambiental CREAL, Barcelona, Espana
Arch Bronconeumol 47:552-60. 2011
..Our aim was to validate the Yale Physical Activity Survey in COPD patients in order to quantify and classify their levels of physical activity...
- Factors affecting the relationship between psychological status and quality of life in COPD patients
Eva Balcells
Servei de Pneumologia, Hospital del Mar IMIM, Passeig Maritim 25 29, 08003 Barcelona, Spain
Health Qual Life Outcomes 8:108. 2010
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Cured meat consumption increases risk of readmission in COPD patientsJordi de Batlle
Centre for Research in Environmental Epidemiology CREAL, Hospital del Mar Research Institute IMIM, CIBER Epidemiologia y Salud Pública CIBERESP, and Dept of Experimental and Health Sciences, Universitat Pompeu Fabra UPF, Barcelona, Spain
Eur Respir J 40:555-60. 2012
..02, 95% CI 1.31-3.12; p=0.001). High cured meat consumption increases the risk of COPD readmission in COPD patients. The assessment of the effectiveness of healthy diet advice should be considered in the future...
- Effects of an integrated care intervention on risk factors of COPD readmission
Judith Garcia-Aymerich
Centre for Research in Environmental Epidemiology, Institut Municipal d Investigacio Medica, Barcelona, Spain
Respir Med 101:1462-9. 2007
..CONCLUSIONS: This IC trial improved disease knowledge, and treatment adherence, after 1 year of intervention, suggesting that these factors may play a role in the prevention of severe COPD exacerbations triggering hospital admissions...
- The effects of regular physical activity on adult-onset asthma incidence in women
Marta Benet
Centre for Research in Environmental Epidemiology, Doctor Aiguader 88, 08003 Barcelona, Catalonia, Spain
Respir Med 105:1104-7. 2011
..Potential benefit of physical activity in asthma incidence is scarce and controversial. We aimed to assess the association between regular physical activity and adult-onset asthma...
- Characteristics of patients admitted for the first time for COPD exacerbation
Eva Balcells
Servei de Pneumologia, Hospital del Mar IMIM, Passeig Maritim 25 29, Barcelona, Spain
Respir Med 103:1293-302. 2009
..This study describes the characteristics of a large sample of patients hospitalised for the first time for a chronic obstructive pulmonary disease (COPD) exacerbation...
- Dietary modulation of oxidative stress in chronic obstructive pulmonary disease patients
Jordi de Batlle
Centre for Research in Environmental Epidemiology CREAL, Barcelona, Spain
Free Radic Res 44:1296-303. 2010
..These results provide new data for a potential dietary modulation of systemic oxidative stress in COPD patients, particularly in those that continue smoking...
- Paradoxical results in the study of risk factors of chronic obstructive pulmonary disease (COPD) re-admission
Judith Garcia-Aymerich
Respiratory and Environmental Health Research Unit, IMIM, Doctor Aiguader 80, 08003 Barcelona, Catalonia, Spain
Respir Med 98:851-7. 2004
..Residual confounding may still account for part of the remaining excess risk. True adverse effects of some pharmacological treatments cannot be excluded...
- Physical activity and its determinants in severe chronic obstructive pulmonary disease
Judith Garcia-Aymerich
Respiratory and Environmental Health Research Unit, Municipal Institute of Medical Research IMIM, Barcelona, Spain
Med Sci Sports Exerc 36:1667-73. 2004
..Surprisingly, little is known about their levels of physical activity practice. We assessed the levels and determinants of physical activity practice in severe COPD patients...
- Health-related quality of life and mortality in male patients with chronic obstructive pulmonary disease
Antonia Domingo-Salvany
Health Services Research Unit and Respiratory and Environmental Health Research Unit, Institut Municipal d Investigacio Medica IMIM IMAS, Barcelona, Spain
Am J Respir Crit Care Med 166:680-5. 2002
..6. HRQL measures provide independent and relevant information on the health status of male patients with COPD. Their use should be considered for a more thorough evaluation and staging of patients with COPD...
- [Phenotypic heterogeneity of chronic obstructive pulmonary disease]
Judith Garcia-Aymerich
Centro de Investigación en Epidemiología Ambiental CREAL, Barcelona, Espana
Arch Bronconeumol 45:129-38. 2009
..The information provided has the potential to increase our understanding of the heterogeneity of COPD phenotypes and help us plan future studies on aspects that are as yet unexplored...
- Regular physical activity modifies smoking-related lung function decline and reduces risk of chronic obstructive pulmonary disease: a population-based cohort study
Judith Garcia-Aymerich
Centre for Research in Environmental Epidemiology CREAL, Institut Municipal d Investigacio Medica IMIM, Doctor Aiguader 88, 08003 Barcelona, Catalonia, Spain
Am J Respir Crit Care Med 175:458-63. 2007
..We hypothesized that higher levels of regular physical activity could reduce the risk of COPD by modifying smoking-related lung function decline...
- Echocardiographic abnormalities in patients with COPD at their first hospital admission
Xavier Freixa
Depts of Cardiology, Hospital Clinic IDIBAPS, University of Barcelona, Barcelona, Spain
Eur Respir J 41:784-91. 2013
..Considering the prognostic and therapeutic implications of cardiac comorbidity, echocardiography should be considered in the assessment of patients with clinically significant COPD...
- Association between Ω3 and Ω6 fatty acid intakes and serum inflammatory markers in COPD
Jordi de Batlle
Centre for Research in Environmental Epidemiology CREAL, Barcelona, Spain
J Nutr Biochem 23:817-21. 2012
..96; P=.034) and CRP (OR=1.95; P=.039) concentrations. Therefore, this study provides the first evidence of an association between dietary intake of omega-3 and omega-6 fatty acids and serum inflammatory markers in COPD patients...
- Mass of intercostal muscles associates with risk of multiple exacerbations in COPD
Roberto Güerri
Servei de Medicina Interna, Hospital del Mar, Barcelona, Spain
Respir Med 104:378-88. 2010
..We hypothesized that a decrease in respiratory muscle mass is associated with increased risk of multiple hospital admissions due to acute exacerbations of the disease...
- Lung function impairment, COPD hospitalisations and subsequent mortality
Judith Garcia-Aymerich
Centre for Research in Environmental Epidemiology CREAL, Barcelona, Spain
Thorax 66:585-90. 2011
..A study was undertaken to examine the associations between lung function impairment and COPD hospitalisation, and COPD hospitalisation and mortality...
- Assessment of dietary patterns in nutritional epidemiology: principal component analysis compared with confirmatory factor analysis
Raphaelle Varraso
INSERM U1018 CESP, Respiratory and Environmental Epidemiology Team Team 5, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif Cedex, France
Am J Clin Nutr 96:1079-92. 2012
..The authors proposed the alternative use of confirmatory factor analysis (CFA) to define such patterns...
- A framework for multiple imputation in cluster analysis
Xavier Basagana
Centre for Research in Environmental Epidemiology, Doctor Aiguader 88, 08003 Barcelona, Catalonia, Spain
Am J Epidemiol 177:718-25. 2013
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- HLA Distribution in COPD Patients
Rosa Faner
1Fundació Investigació Sanitaria Illes Balears FISIB, Palma de Mallorca, Barcelona, Spain
COPD 10:138-46. 2013
..Conclusions: By and large, HLA distribution was similar in COPD patients and controls, but the HLA class II allele DRB1*14 may contribute to the pathogenesis of severe COPD with emphysema...
- Telemedicine enhances quality of forced spirometry in primary care
Felip Burgos
Servei de Pneumologia, HospitalClínic, CIBER de Enfermedades Respiratorias, Universitat de Barcelona, Barcelona, Spain
Eur Respir J 39:1313-8. 2012
..The web-based remote support for primary care by specialists generated a sustained positive impact on quality of testing. The study expands the potential of primary care for diagnosis and management of patients with pulmonary diseases...
- Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar
Josep M Anto
Centre for Research in Environmental Epidemiology, Barcelona, Spain
J Allergy Clin Immunol 129:943-54.e4. 2012
..This review helps to define phenotypes of allergic diseases in MeDALL...
- Validity of instruments to measure physical activity may be questionable due to a lack of conceptual frameworks: a systematic review
Elena Gimeno-Santos
Centre for Research in Environmental Epidemiology, Barcelona, Spain
Health Qual Life Outcomes 9:86. 2011
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- Differences in COPD care among doctors who control the disease: general practitioner vs. pneumologist
Judith Garcia-Aymerich
Respiratory and Environmental Health Research Unit, , Doctor Aiguader 80, E-08003-Barcelona, Catalonia, Spain
Respir Med 100:332-9. 2006
..Medical control of COPD patients needs more investigation and a wider inclusion in international guidelines...
- [Rate and characteristics of asthma exacerbations: the ASMAB I study]
Ferran Morell
Servei de Pneumologia, Hospital Universitari Vall d Hebron, Barcelona, Spain
Arch Bronconeumol 44:303-11. 2008
..The aim of this study was to determine the incidence and clinical characteristics of asthma exacerbations seen by emergency services in Barcelona, Spain (the ASMAB-I study)...
- [Evaluation of regular physical activity in COPD patients with an accelerometer and a questionnaire: a pilot study]
Eva Balcells Vilarnau
Arch Bronconeumol 43:524-5. 2007
- Physical activity and bronchial hyperresponsiveness: European Community Respiratory Health Survey II
Rafea Shaaban
INSERM U700, Epidémiologie des Maladies Respiratoires, Faculte Xavier Bichat, BP 416, 16 rue Henri Huchard, 75018 Paris, France
Thorax 62:403-10. 2007
..The relationship between physical activity and BHR in men and women aged 28.0-56.5 years randomly selected from 24 centres in 11 countries participating in the European Community Respiratory Health Survey II was investigated...
