Tamara García-Barrera

Summary

Publications

  1. doi request reprint Biological responses related to agonistic, antagonistic and synergistic interactions of chemical species
    T García-Barrera
    Department of Chemistry and Materials Science, Faculty of Experimental Sciences, University of Huelva, Huelva, Spain
    Anal Bioanal Chem 403:2237-53. 2012
  2. doi request reprint Characterization of metal profiles in serum during the progression of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Science, University of Huelva, Campus de El Carmen, 21007, Huelva, Spain
    Metallomics 6:292-300. 2014
  3. doi request reprint Antagonistic interaction of selenomethionine enantiomers on methylmercury toxicity in the microalgae Chlorella sorokiniana
    Fernando Moreno
    Environmental and Bioanalytical Chemistry Group, Departamento de Química y Ciencia de los Materiales Profesor José Carlos Vílchez Martín, Facultad de Ciencias Experimentales, Universidad de Huelva, Campus El Carmen, 21007 Huelva, Spain
    Metallomics 6:347-55. 2014
  4. doi request reprint Elucidation of the defence mechanism in microalgae Chlorella sorokiniana under mercury exposure. Identification of Hg-phytochelatins
    Verónica Gómez-Jacinto
    Environmental and Bioanalytical Chemistry Group, Departamento de Química y Ciencia de los Materiales Profesor José Carlos Vílchez Martín, Facultad de Ciencias Experimentales, Universidad de Huelva, Campus El Carmen, 21007 Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Spain International Campus of Excellence on Agrofood ceiA3, University of Huelva, Spain Electronic address
    Chem Biol Interact 238:82-90. 2015
  5. doi request reprint Application of metabolomics based on direct mass spectrometry analysis for the elucidation of altered metabolic pathways in serum from the APP/PS1 transgenic model of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry and CC MM Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain
    J Pharm Biomed Anal 107:378-85. 2015
  6. doi request reprint Deciphering metabolic abnormalities associated with Alzheimer's disease in the APP/PS1 mouse model using integrated metabolomic approaches
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain
    Biochimie 110:119-28. 2015
  7. doi request reprint Metabolomic screening of regional brain alterations in the APP/PS1 transgenic model of Alzheimer's disease by direct infusion mass spectrometry
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain
    J Pharm Biomed Anal 102:425-35. 2015
  8. doi request reprint Metabolomics reveals significant impairments in the immune system of the APP/PS1 transgenic mice of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry and CCMM, Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, Huelva, Spain
    Electrophoresis 36:577-87. 2015
  9. doi request reprint Application of a novel metabolomic approach based on atmospheric pressure photoionization mass spectrometry using flow injection analysis for the study of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Science, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Electronic address
    Talanta 131:480-9. 2015
  10. doi request reprint Region-specific metabolic alterations in the brain of the APP/PS1 transgenic mice of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry, CC MM, Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Electronic address
    Biochim Biophys Acta 1842:2395-402. 2014

Collaborators

  • Jürgen Gailer
  • Raúl González-Domínguez
  • José Luis Gómez-Ariza
  • Miguel Ángel García-Sevillano
  • Javier Vitorica
  • Verónica Gómez-Jacinto
  • Carlos Vílchez-Lobato
  • Inés Garbayo-Nores
  • Fernando Moreno
  • Amanda Gago-Tinoco
  • Rocío Castilla-Quintero
  • M J Bebianno
  • Nieves Abril
  • Juan López-Barea
  • Francisco Navarro
  • Francisco Navarro-Roldán
  • Antonia Garcia
  • Julián Blasco-Moreno
  • José Luiz Gómez-Ariza
  • Coral Barbas
  • Zaida Montero-Lobato
  • Carmen Pueyo
  • Elham Zeini Jahromi
  • Macarena González-Fernández
  • Fernando Lorenzo

Detail Information

Publications21

  1. doi request reprint Biological responses related to agonistic, antagonistic and synergistic interactions of chemical species
    T García-Barrera
    Department of Chemistry and Materials Science, Faculty of Experimental Sciences, University of Huelva, Huelva, Spain
    Anal Bioanal Chem 403:2237-53. 2012
    ..In the present paper, the interactions of the most widely studied elements in this context (Se, Hg and As) are discussed, as well as other important interactions between different elements...
  2. doi request reprint Characterization of metal profiles in serum during the progression of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Science, University of Huelva, Campus de El Carmen, 21007, Huelva, Spain
    Metallomics 6:292-300. 2014
    ..Finally, correlation analysis indicated that these metal abnormalities can be interrelated, participating in common processes such as oxidative stress, altered homeostasis and uptake into brain, as well as impaired glucose metabolism. ..
  3. doi request reprint Antagonistic interaction of selenomethionine enantiomers on methylmercury toxicity in the microalgae Chlorella sorokiniana
    Fernando Moreno
    Environmental and Bioanalytical Chemistry Group, Departamento de Química y Ciencia de los Materiales Profesor José Carlos Vílchez Martín, Facultad de Ciencias Experimentales, Universidad de Huelva, Campus El Carmen, 21007 Huelva, Spain
    Metallomics 6:347-55. 2014
    ..The present paper reports new data about the relationship between the mechanism of detoxification of methylmercury and selenomethionine enantiomers through the study of the metabolic intermediates by means of speciation analysis...
  4. doi request reprint Elucidation of the defence mechanism in microalgae Chlorella sorokiniana under mercury exposure. Identification of Hg-phytochelatins
    Verónica Gómez-Jacinto
    Environmental and Bioanalytical Chemistry Group, Departamento de Química y Ciencia de los Materiales Profesor José Carlos Vílchez Martín, Facultad de Ciencias Experimentales, Universidad de Huelva, Campus El Carmen, 21007 Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Spain International Campus of Excellence on Agrofood ceiA3, University of Huelva, Spain Electronic address
    Chem Biol Interact 238:82-90. 2015
    ....
  5. doi request reprint Application of metabolomics based on direct mass spectrometry analysis for the elucidation of altered metabolic pathways in serum from the APP/PS1 transgenic model of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry and CC MM Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain
    J Pharm Biomed Anal 107:378-85. 2015
    ....
  6. doi request reprint Deciphering metabolic abnormalities associated with Alzheimer's disease in the APP/PS1 mouse model using integrated metabolomic approaches
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain
    Biochimie 110:119-28. 2015
    ..Therefore, these results demonstrate the potential of metabolomics and the use of transgenic animal models to understand the pathogenesis of Alzheimer's disease. ..
  7. doi request reprint Metabolomic screening of regional brain alterations in the APP/PS1 transgenic model of Alzheimer's disease by direct infusion mass spectrometry
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain
    J Pharm Biomed Anal 102:425-35. 2015
    ..Therefore, these findings demonstrate the potential of metabolomic screening and the use of transgenic models for understanding pathogenesis of Alzheimer's disease. ..
  8. doi request reprint Metabolomics reveals significant impairments in the immune system of the APP/PS1 transgenic mice of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry and CCMM, Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, Huelva, Spain
    Electrophoresis 36:577-87. 2015
    ..Therefore, these findings highlight the importance of the proper metabolic functioning of peripheral immune system in the development of neurodegenerative disorders such as AD. ..
  9. doi request reprint Application of a novel metabolomic approach based on atmospheric pressure photoionization mass spectrometry using flow injection analysis for the study of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Science, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Electronic address
    Talanta 131:480-9. 2015
    ..Therefore, it could be concluded that this metabolomic tool presents a great potential for analysis of biological samples, considering its high-throughput screening capability, fast analysis and comprehensive metabolite coverage...
  10. doi request reprint Region-specific metabolic alterations in the brain of the APP/PS1 transgenic mice of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry, CC MM, Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Electronic address
    Biochim Biophys Acta 1842:2395-402. 2014
    ..g. glutamate, glycine, serine, N-acetyl-aspartate), not previously described to our knowledge. Therefore, these findings could provide a new insight into brain pathology in Alzheimer's disease. ..
  11. doi request reprint Metabolite profiling for the identification of altered metabolic pathways in Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Science, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain Electronic address
    J Pharm Biomed Anal 107:75-81. 2015
    ....
  12. doi request reprint Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Science, University of Huelva, Huelva, Spain Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Huelva, Spain
    Electrophoresis 35:3321-30. 2014
    ..However, the most interesting results are related to the association of several vascular risk factors with Alzheimer's disease. ..
  13. doi request reprint Development of a metabolomic approach based on urine samples and direct infusion mass spectrometry
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Science, Campus de El Carmen, University of Huelva, 21007 Huelva, Spain International Campus of Excellence on Agrofood ceiA3, University of Huelva, 21007 Huelva, Spain Research Center of Health and Environment CYSMA, Campus de El Carmen, University of Huelva, 21007 Huelva, Spain
    Anal Biochem 465:20-7. 2014
    ..Finally, the optimized approach was tested in a pilot metabolomic investigation of urine samples from transgenic mice models of Alzheimer's disease (APP/PS1) in order to illustrate the potential of the methodology. ..
  14. doi request reprint Use of elemental and molecular-mass spectrometry to assess the toxicological effects of inorganic mercury in the mouse Mus musculus
    Miguel Ángel García-Sevillano
    Department of Chemistry and Materials Science, Faculty of Experimental Science, University of Huelva, Campus de El Carmen, 21007, Huelva, Spain
    Anal Bioanal Chem 406:5853-65. 2014
    ....
  15. doi request reprint Metabolic signatures associated with environmental pollution by metals in Doñana National Park using P. clarkii as bioindicator
    Amanda Gago-Tinoco
    Department of Chemistry and Material Science, Faculty of Experimental Sciences, University of Huelva, Campus de El Carmen, 21007, Huelva, Spain
    Environ Sci Pollut Res Int 21:13315-23. 2014
    ..In this way, metal-induced toxicity could be related to metabolic impairments, principally oxidative stress, metabolic dysfunction, and dyslipidemia. ..
  16. doi request reprint Homeostasis of metals in the progression of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Science, University of Huelva, Campus de El Carmen, 21007, Huelva, Spain
    Biometals 27:539-49. 2014
    ..Therefore, this study may contribute to our understanding of the pathological mechanisms related to metals in Alzheimer's disease. ..
  17. doi request reprint Omics technologies and their applications to evaluate metal toxicity in mice M. spretus as a bioindicator
    Miguel Ángel García-Sevillano
    Department of Chemistry and Materials Science, Faculty of Experimental Science, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain International Agrofood Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain
    J Proteomics 104:4-23. 2014
    ..This article is part of a Special Issue entitled: Environmental and structural proteomics...
  18. doi request reprint Combination of metabolomic and phospholipid-profiling approaches for the study of Alzheimer's disease
    Raúl González-Domínguez
    Department of Chemistry and CC MM, Faculty of Experimental Science, University of Huelva, Campus de El Carmen, 21007, Huelva, Spain International Agrofood Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007, Huelva, Spain
    J Proteomics 104:37-47. 2014
    ....
  19. ncbi request reprint Comparative study of atomic fluorescence spectroscopy and inductively coupled plasma mass spectrometry for mercury and arsenic multispeciation
    José Luis Gómez-Ariza
    Dpto Química y CC MM, Facultad de Ciencias Experimentales, Universidad de Huelva, Campus de El Carmen, 21071, Huelva, Spain
    Anal Bioanal Chem 382:485-92. 2005
    ....
  20. doi request reprint A combination of metallomics and metabolomics studies to evaluate the effects of metal interactions in mammals. Application to Mus musculus mice under arsenic/cadmium exposure
    Miguel Ángel García-Sevillano
    Department of Chemistry and Materials Science, Faculty of Experimental Science, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain International Agrofood Campus of Excellence International ceiA3, University of Huelva, Spain Research Center of Health and Environment CYSMA, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain
    J Proteomics 104:66-79. 2014
    ..In addition, heavy metal and metalloid causes differential liver injury, manifested by steatosis (non-alcoholic fatty liver disease, NAFLD) and infiltration of blood cells into the space of Disse...
  21. doi request reprint Liquid chromatography-inductively coupled plasma-based metallomic approaches to probe health-relevant interactions between xenobiotics and mammalian organisms
    José Luis Gómez-Ariza
    Department of Chemistry and Material Sciences, Faculty of Experimental Science, University of Huelva, Campus de El Carmen, 21007 Huelva, Spain
    Metallomics 3:566-77. 2011
    ....