Genomes and Genes


Francisco García de Gracia



  1. Acevedo M, García de Gracia F, Miranda Cárdenas C, Soto Rifo R, Aguayo F, Leon O. Differences in the internalization of self-inactivating VSVG-pseudotyped murine leukemia virus-based vectors in human and murine cells. J Virol Methods. 2018;255:14-22 pubmed publisher
    ..In conclusion, the SIN-VSVG-MLV vector showed significantly different rates of infectivity depending on the host cell type, possibly due to differential rates of viral internalization. ..
  2. Ajamian L, Abel K, Rao S, Vyboh K, García de Gracia F, Soto Rifo R, et al. HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA. Biomolecules. 2015;5:2808-39 pubmed publisher
    ..This work uncovers a novel and unique regulatory circuit involving several UPF proteins that ultimately regulate vRNA nuclear export and trafficking. ..