Cao X, Dang L, Zheng X, Lu Y, Lu Y, Ji R, et al
. Targeting super-enhancer-driven oncogenic transcription by CDK7 inhibition in anaplastic thyroid cancer. Thyroid. 2019;: pubmed publisher
..Taken together, these findings demonstrate transcriptional addiction in ATC pathobiology and identify CDK7 and PPP1R15A as potential biomarkers and therapeutic targets for ATC. ..
Sun Y, Du F, Gao M, Ji Q, Li Z, Zhang Y, et al
. Anlotinib for the Treatment of Patients With Locally Advanced or Metastatic Medullary Thyroid Cancer. Thyroid. 2018;: pubmed publisher
..Anlotinib demonstrated a durable antitumor activity with manageable adverse event profile in locally advanced or metastatic MTC. ..
Deng X, Feng N, Zheng M, Ye X, Lin H, Yu X, et al
. PM2.5 exposure-induced autophagy is mediated by lncRNA loc146880 which also promotes the migration and invasion of lung cancer cells. Biochim Biophys Acta Gen Subj. 2017;1861:112-125 pubmed publisher
..The lncRNA, in turn, up-regulates autophagy and promotes the malignant behaviors of lung cancer cells. The results show the toxicological effects of PM2.5 in lung tumor progression and metastasis. ..
Liu C, Yu Y, Yin G, Zhang J, Wen W, Ruan X, et al
. C14orf93 (RTFC) is identified as a novel susceptibility gene for familial nonmedullary thyroid cancer. Biochem Biophys Res Commun. 2017;482:590-596 pubmed publisher
..The R115Q, V205M and G209D RTFC mutants enhance the colony forming capacity of thyroid cancer cells, and are able to transform normal thyroid cells. In summary, our data suggest the roles of RTFC in thyroid carcinogenesis. ..