Soren Gantt

Summary

Publications

  1. doi request reprint Human herpesvirus 8-associated neoplasms: the roles of viral replication and antiviral treatment
    Soren Gantt
    Department of Pediatrics, University of Washington, Seattle Children s Hospital, Seattle, WA 98101, USA
    Curr Opin Infect Dis 24:295-301. 2011
  2. pmc The immunologic basis for severe neonatal herpes disease and potential strategies for therapeutic intervention
    Soren Gantt
    Department of Pediatrics, Division of Infectious Diseases, University of Washington and Seattle Children s Hospital, Seattle, WA 98105, USA
    Clin Dev Immunol 2013:369172. 2013
  3. pmc Clinical presentation and outcome of epidemic Kaposi sarcoma in Ugandan children
    Soren Gantt
    Seattle Children s Hospital, Seattle, WA, USA
    Pediatr Blood Cancer 54:670-4. 2010
  4. pmc Genetic analyses of HIV-1 env sequences demonstrate limited compartmentalization in breast milk and suggest viral replication within the breast that increases with mastitis
    Soren Gantt
    Department of Pediatrics, Seattle Children s Hospital Research Institute, 1900 Ninth Ave, Seattle, WA 98101 1304, USA
    J Virol 84:10812-9. 2010
  5. pmc Cytomegalovirus and Epstein-Barr virus in breast milk are associated with HIV-1 shedding but not with mastitis
    Soren Gantt
    Departments of Pediatrics, Seattle Children s Hospital Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA
    AIDS 22:1453-60. 2008
  6. pmc Effects of short-course zidovudine on the selection of nevirapine-resistant HIV-1 in women taking single-dose nevirapine
    Mark A Micek
    University of Washington, Seattle, Washington, USA
    J Infect Dis 205:1811-5. 2012
  7. ncbi request reprint Laboratory indicators of mastitis are not associated with elevated HIV-1 DNA loads or predictive of HIV-1 RNA loads in breast milk
    Soren Gantt
    Department of Pediatrics, University of Washington, Seattle, WA 98109, USA
    J Infect Dis 196:570-6. 2007
  8. pmc The HIV protease inhibitor nelfinavir inhibits Kaposi's sarcoma-associated herpesvirus replication in vitro
    Soren Gantt
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    Antimicrob Agents Chemother 55:2696-703. 2011
  9. doi request reprint An artesunate-containing antimalarial treatment regimen did not suppress cytomegalovirus viremia
    Soren Gantt
    Seattle Children s Hospital, Seattle, WA, USA
    J Clin Virol 58:276-8. 2013
  10. doi request reprint Valganciclovir dosing using area under the curve calculations in pediatric solid organ transplant recipients
    David Villeneuve
    Department of Pharmacy, Seattle Children s Hospital, Seattle, WA, USA
    Pediatr Transplant 17:80-5. 2013

Detail Information

Publications13

  1. doi request reprint Human herpesvirus 8-associated neoplasms: the roles of viral replication and antiviral treatment
    Soren Gantt
    Department of Pediatrics, University of Washington, Seattle Children s Hospital, Seattle, WA 98101, USA
    Curr Opin Infect Dis 24:295-301. 2011
    ..In this review, we highlight the importance of human herpesvirus 8 (HHV-8) lytic replication and the potential for antiviral therapies to prevent or treat HHV-8-related neoplasms...
  2. pmc The immunologic basis for severe neonatal herpes disease and potential strategies for therapeutic intervention
    Soren Gantt
    Department of Pediatrics, Division of Infectious Diseases, University of Washington and Seattle Children s Hospital, Seattle, WA 98105, USA
    Clin Dev Immunol 2013:369172. 2013
    ....
  3. pmc Clinical presentation and outcome of epidemic Kaposi sarcoma in Ugandan children
    Soren Gantt
    Seattle Children s Hospital, Seattle, WA, USA
    Pediatr Blood Cancer 54:670-4. 2010
    ..Kaposi sarcoma (KS) is one of the most common pediatric cancers in sub-Saharan Africa. Few data are available about the clinical presentation or response to treatment of children with epidemic (HIV-associated) KS...
  4. pmc Genetic analyses of HIV-1 env sequences demonstrate limited compartmentalization in breast milk and suggest viral replication within the breast that increases with mastitis
    Soren Gantt
    Department of Pediatrics, Seattle Children s Hospital Research Institute, 1900 Ninth Ave, Seattle, WA 98101 1304, USA
    J Virol 84:10812-9. 2010
    ..However, phylogenetic trees demonstrate extensive mixing of viruses between milk and blood specimens. HIV-1 replication in breast milk appears to increase with inflammation, contributing to higher milk viral loads during mastitis...
  5. pmc Cytomegalovirus and Epstein-Barr virus in breast milk are associated with HIV-1 shedding but not with mastitis
    Soren Gantt
    Departments of Pediatrics, Seattle Children s Hospital Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA
    AIDS 22:1453-60. 2008
    ..Bacterial infections may cause clinical mastitis, but whether other copathogens common in HIV-1 infection are associated with subclinical mastitis or HIV-1 shedding is unknown...
  6. pmc Effects of short-course zidovudine on the selection of nevirapine-resistant HIV-1 in women taking single-dose nevirapine
    Mark A Micek
    University of Washington, Seattle, Washington, USA
    J Infect Dis 205:1811-5. 2012
    ..003). NVP mutants decayed to <2% in 24/35 (68.6%) at a median 6 months postpartum, with no differences based on ZDV use (logrank P = .99). Short-course ZDV was associated with reduced NVP-resistance mutations among women taking sdNVP...
  7. ncbi request reprint Laboratory indicators of mastitis are not associated with elevated HIV-1 DNA loads or predictive of HIV-1 RNA loads in breast milk
    Soren Gantt
    Department of Pediatrics, University of Washington, Seattle, WA 98109, USA
    J Infect Dis 196:570-6. 2007
    ..An improved understanding of the relationship between indicators of inflammation and HIV-1 loads in breast milk could improve MTCT prevention strategies...
  8. pmc The HIV protease inhibitor nelfinavir inhibits Kaposi's sarcoma-associated herpesvirus replication in vitro
    Soren Gantt
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    Antimicrob Agents Chemother 55:2696-703. 2011
    ..Nelfinavir may provide unique benefits for the prevention or treatment of HIV-associated KS and potentially other human herpesviruses by direct inhibition of replication...
  9. doi request reprint An artesunate-containing antimalarial treatment regimen did not suppress cytomegalovirus viremia
    Soren Gantt
    Seattle Children s Hospital, Seattle, WA, USA
    J Clin Virol 58:276-8. 2013
    ..Only a small number of case reports are available describing the clinical effects of artesunate on CMV infection, and these yielded inconsistent results...
  10. doi request reprint Valganciclovir dosing using area under the curve calculations in pediatric solid organ transplant recipients
    David Villeneuve
    Department of Pharmacy, Seattle Children s Hospital, Seattle, WA, USA
    Pediatr Transplant 17:80-5. 2013
    ..An AUC calculated using two sample times might allow for fewer blood draws in the future...
  11. pmc Nevirapine resistance by timing of HIV type 1 infection in infants treated with single-dose nevirapine
    Mark A Micek
    Department of Global Health, University of Washington, Seattle, Washington, USA
    Clin Infect Dis 50:1405-14. 2010
    ..We hypothesized that the selection, acquisition, and decay of nevirapine-resistant HIV-1 differs in infants, varying by the timing of HIV-1 infection...
  12. doi request reprint Insights into the broad cellular effects of nelfinavir and the HIV protease inhibitors supporting their role in cancer treatment and prevention
    Soren Gantt
    University of British Columbia, Child and Family Research Institute, Room A5 147, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada
    Curr Opin Oncol 25:495-502. 2013
    ..With the widespread use of protease inhibitors, there was a reduction in the incidence and mortality of HIV-associated malignancies. Studies later found these drugs to have promising direct antitumor effects...
  13. doi request reprint Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump
    Xuan Qin
    Microbiology Laboratory, A9601, Seattle Children s Hospital, 4800 Sand Point Way, NE, Seattle, WA 98105, USA
    Int J Antimicrob Agents 38:81-3. 2011
    ..aureus. The native plasmids carrying vga(A)(LC) were transferable to a susceptible laboratory strain of S. aureus in vitro, in which they conferred resistance patterns similar to the parent isolates...