Gary L Gallia

Summary

Publications

  1. ncbi Lumbopelvic reconstruction after combined L5 spondylectomy and total sacrectomy for en bloc resection of a malignant fibrous histiocytoma
    Gary L Gallia
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Neurosurgery 67:E498-502. 2010
  2. pmc Erlotinib inhibits growth of a patient-derived chordoma xenograft
    I Mei Siu
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 8:e78895. 2013
  3. ncbi Total L-5 spondylectomy and reconstruction of the lumbosacral junction. Technical note
    Gary L Gallia
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Neurosurg Spine 7:103-11. 2007
  4. doi Establishment of a human glioblastoma stemlike brainstem rodent tumor model
    I Mei Siu
    Departments of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    J Neurosurg Pediatr 6:92-7. 2010
  5. pmc Factors associated with survival for patients with glioblastoma with poor pre-operative functional status
    Kaisorn L Chaichana
    Neuro Oncology Outcomes Laboratory, Department of Neurosurgery, Johns Hopkins University, Baltimore, MD 21202, USA
    J Clin Neurosci 20:818-23. 2013
  6. doi Seizure control for patients undergoing meningioma surgery
    Kaisorn L Chaichana
    Department of Neurosurgery, Neuro Oncology Outcomes Laboratory, Johns Hopkins University, Baltimore, Maryland, USA
    World Neurosurg 79:515-24. 2013
  7. pmc Evaluation of tyrosine kinase inhibitor combinations for glioblastoma therapy
    Avadhut D Joshi
    Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 7:e44372. 2012
  8. ncbi Evaluation of a system for high-accuracy 3D image-based registration of endoscopic video to C-arm cone-beam CT for image-guided skull base surgery
    Daniel J Mirota
    Department of Computer Science, Johns Hopkins University, Baltimore, MD 21218, USA
    IEEE Trans Med Imaging 32:1215-26. 2013
  9. doi Endoscopic resection of esthesioneuroblastoma
    Gary L Gallia
    Department of Neurosurgery, Phipps Building, Room 101, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    J Clin Neurosci 19:1478-82. 2012
  10. ncbi Thoracic kyphotic deformity reduction with a distractible titanium cage via an entirely posterior approach
    Daniel M Sciubba
    Department of Neurological Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Neurosurgery 60:223-30; discussion 230-1. 2007

Detail Information

Publications61

  1. ncbi Lumbopelvic reconstruction after combined L5 spondylectomy and total sacrectomy for en bloc resection of a malignant fibrous histiocytoma
    Gary L Gallia
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Neurosurgery 67:E498-502. 2010
    ..Primary sacral neoplasms that extend superiorly to involve the distal lumbar spine represent complex surgical problems. Treatment options for these patients are often limited to hemicorporectomy...
  2. pmc Erlotinib inhibits growth of a patient-derived chordoma xenograft
    I Mei Siu
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 8:e78895. 2013
    ..This is the first demonstration of antitumor activity in a patient-derived chordoma xenograft model and these findings support further evaluation of EGFR inhibitors in this disease. ..
  3. ncbi Total L-5 spondylectomy and reconstruction of the lumbosacral junction. Technical note
    Gary L Gallia
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Neurosurg Spine 7:103-11. 2007
    ..The authors conclude that this technique can be safely performed in appropriately selected patients with neoplasms involving L-5...
  4. doi Establishment of a human glioblastoma stemlike brainstem rodent tumor model
    I Mei Siu
    Departments of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    J Neurosurg Pediatr 6:92-7. 2010
    ..It is therefore essential to develop a reliable animal model to screen new therapeutic agents for the treatment of this type of tumor...
  5. pmc Factors associated with survival for patients with glioblastoma with poor pre-operative functional status
    Kaisorn L Chaichana
    Neuro Oncology Outcomes Laboratory, Department of Neurosurgery, Johns Hopkins University, Baltimore, MD 21202, USA
    J Clin Neurosci 20:818-23. 2013
    ..005), tumor size >2 cm (p = 0.01), radical tumor resection (p=0.01), and temozolomide (p = 0.001). This study identifies a subset of patients with poor functional status who may benefit from aggressive surgical resection...
  6. doi Seizure control for patients undergoing meningioma surgery
    Kaisorn L Chaichana
    Department of Neurosurgery, Neuro Oncology Outcomes Laboratory, Johns Hopkins University, Baltimore, Maryland, USA
    World Neurosurg 79:515-24. 2013
    ..The factors associated with the onset of seizures as well as factors associated with seizure control remains poorly understood...
  7. pmc Evaluation of tyrosine kinase inhibitor combinations for glioblastoma therapy
    Avadhut D Joshi
    Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 7:e44372. 2012
    ..Improved targeted therapies, with drug properties favorable to intracranial tumors, are likely required to form effective drug combinations for GBM...
  8. ncbi Evaluation of a system for high-accuracy 3D image-based registration of endoscopic video to C-arm cone-beam CT for image-guided skull base surgery
    Daniel J Mirota
    Department of Computer Science, Johns Hopkins University, Baltimore, MD 21218, USA
    IEEE Trans Med Imaging 32:1215-26. 2013
    ..82 mm for the conventional tracker-based method. Image-based registration was highly robust against CBCT image quality factors of noise and resolution, permitting integration with low-dose intraoperative CBCT. ..
  9. doi Endoscopic resection of esthesioneuroblastoma
    Gary L Gallia
    Department of Neurosurgery, Phipps Building, Room 101, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    J Clin Neurosci 19:1478-82. 2012
    ..Longer follow-up on larger numbers of patients is required to clarify the utility of purely endoscopic approaches in the management of this malignant tumor...
  10. ncbi Thoracic kyphotic deformity reduction with a distractible titanium cage via an entirely posterior approach
    Daniel M Sciubba
    Department of Neurological Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Neurosurgery 60:223-30; discussion 230-1. 2007
    ..We describe a technique in which kyphotic deformity of the thoracic and thoracolumbar spine is corrected, decompressed, and stabilized with a circumferential fixation construct from a lone posterior approach...
  11. pmc Establishment and characterization of a primary human chordoma xenograft model
    I Mei Siu
    Department of Neurosurgery, The Johns Hopkins University, Baltimore, MD, USA
    J Neurosurg 116:801-9. 2012
    ..Currently, there are only a few established chordoma cell lines and no primary xenograft model. In this study, the authors aimed to develop a primary chordoma xenograft model...
  12. doi Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells
    Gary L Gallia
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Mol Cancer Ther 8:386-93. 2009
    ..These results suggest that local delivery of an Akt small-molecule inhibitor is effective against experimental intracranial glioma, with no observed resistance to glioblastoma multiforme cells grown in stem cell conditions...
  13. doi Endonasal endoscopic resection of esthesioneuroblastoma: the Johns Hopkins Hospital experience and review of the literature
    Gary L Gallia
    Department of Neurosurgery, Johns Hopkins Hospital, 600 North Wolfe Street, Phipps Building, Baltimore, MD 21287, USA
    Neurosurg Rev 34:465-75. 2011
    ..Longer follow-up on a larger number of patients is required to further demonstrate the utility of endoscopic approaches in the management of this malignancy...
  14. pmc Multiple resections for patients with glioblastoma: prolonging survival
    Kaisorn L Chaichana
    Department of Neurosurgery, Johns Hopkins University, Baltimore, MD 21202, USA
    J Neurosurg 118:812-20. 2013
    ....
  15. pmc Extra-dimensional Demons: a method for incorporating missing tissue in deformable image registration
    Sajendra Nithiananthan
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA
    Med Phys 39:5718-31. 2012
    ..Tissue excision is explicitly modeled by increasing the dimensionality of the deformation field to allow motion beyond the dimensionality of the image. The accuracy of the model is tested in phantom, simulations, and cadaver models...
  16. pmc The genetic landscape of the childhood cancer medulloblastoma
    D Williams Parsons
    Ludwig Center for Cancer Genetics and Therapeutics and Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21231, USA
    Science 331:435-9. 2011
    ....
  17. ncbi Spinal pelvic reconstruction after total sacrectomy for en bloc resection of a giant sacral chordoma. Technical note
    Gary L Gallia
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland 21287 7713, USA
    J Neurosurg Spine 3:501-6. 2005
    ..They describe a novel spinal pelvic reconstruction technique that addresses some of the biomechanical limitations...
  18. doi An objective and automated method for assessing surgical skill in endoscopic sinus surgery using eye-tracking and tool-motion data
    Narges Ahmidi
    Department of Computer Science, The Johns Hopkins University, Baltimore, MD 21287, USA
    Int Forum Allergy Rhinol 2:507-15. 2012
    ..We investigate this hypothesis by developing a statistical model of surgery and testing the model experimentally in the context of endoscopic sinus surgery (ESS)...
  19. doi Craniofacial resection of midline anterior skull base malignancies: a reassessment of outcomes in the modern era
    Shaan M Raza
    Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    World Neurosurg 78:128-36. 2012
    ..Given recent advancements in open surgical approaches, there is a need to review the technique of open craniofacial resection in the modern surgical era...
  20. pmc Evaluation of retinoic acid therapy for OTX2-positive medulloblastomas
    Renyuan Bai
    Department of Neurosurgery, Johns Hopkins University, CRB II Rm 257, 1550 Orleans Street, Baltimore, MD 21231, USA
    Neuro Oncol 12:655-63. 2010
    ..These findings suggest a mechanism for RA-mediated anti-tumor effect on OTX2-positive MB cells and indicate that therapeutic targeting of OTX2 might be effective if FGF pathway-mediated resistance can be overcome...
  21. doi Animal model of intramedullary spinal cord glioma using human glioblastoma multiforme neurospheres
    Wesley Hsu
    Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    J Neurosurg Spine 16:315-9. 2012
    ..In this study, the authors' goal was to develop a novel spinal cord tumor model using a human neurosphere cell line...
  22. ncbi Targeting the AKT pathway in glioblastoma
    Kelli A McDowell
    Ludwig Collaborative Laboratory, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Curr Pharm Des 17:2411-20. 2011
    ..Inhibitors of the Akt pathway represent a potential treatment option against GBM and additional research efforts are required to fully explore and develop this possible treatment strategy...
  23. doi Glioblastoma multiforme in the Muir-Torre syndrome
    Zev A Binder
    Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Clin Neurol Neurosurg 113:411-5. 2011
    ..Immunohistochemical analysis of the patient's colon carcinoma and his GBM both revealed loss of the mismatch repair proteins mutS homolog 2 (MSH2) and mutS homolog 6 (MSH6)...
  24. pmc Local delivery of rapamycin: a toxicity and efficacy study in an experimental malignant glioma model in rats
    Betty Tyler
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, USA
    Neuro Oncol 13:700-9. 2011
    ..These results suggest that the local delivery of rapamycin for the treatment of gliomas should be further investigated...
  25. doi Expanded endonasal endoscopic approach for resection of a growth hormone-secreting pituitary macroadenoma coexistent with a cavernous carotid artery aneurysm
    Xuewei Xia
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    J Clin Neurosci 19:1437-41. 2012
    ..Vascular imaging studies and a low index for suspicion are required for preoperative identification of such complex situations...
  26. doi Expanded endonasal endoscopic approach for resection of a skull base low-grade smooth muscle neoplasm
    Vafi Salmasi
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Childs Nerv Syst 28:151-8. 2012
    ..This case adds to the growing body of literature supporting a role for endoscopic procedures in the treatment of skull base pathologies in pediatric patients...
  27. doi Perioperative and long-term outcomes from the management of parasagittal meningiomas invading the superior sagittal sinus
    Shaan M Raza
    Division of Neurosurgical Oncology, Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    Neurosurgery 67:885-93; discussion 893. 2010
    ..Invasion is often considered a contraindication to surgery because of associated morbidity, such as cerebral venous thrombosis...
  28. ncbi Epilepsy and temporal lobe injury after skull base proton beam therapy
    Ricardo Horacio Roda
    Department of Neurology, Room 5050, Outpatient Center, Johns Hopkins University School of Medicine, 601 North Caroline Street, Baltimore, Maryland 21287, USA
    J Clin Neurosci 16:1220-1. 2009
    ..We present three patients who developed temporal lobe injury and epilepsy after proton beam therapy to the skull base. This particular form of treatment-related toxicity should be considered when treating skull base tumors...
  29. doi Solitary spinal metastasis of Hürthle cell thyroid carcinoma
    Daniel M Sciubba
    Department of Neurosurgery, Johns Hopkins University, 600 N Wolfe Street, Meyer 8 161, Baltimore, MD 21287, USA
    J Clin Neurosci 17:797-801. 2010
    ..We discuss aspects of the diagnosis, management, patient selection, and surgical treatment of metastatic Hürthle cell carcinoma in reference to the literature...
  30. ncbi Perioperative continuous cerebrospinal fluid pressure monitoring in patients with spontaneous cerebrospinal fluid leaks: presentation of a novel technique
    Douglas D Reh
    Johns Hopkins Sinus Center, The Johns Hopkins University, School of Medicine, 601 N Caroline Street, Baltimore, MD 21287, USA
    Am J Rhinol Allergy 24:238-43. 2010
    ..We propose a novel technique for more accurate measurement of CSFP in patients with spontaneous CSF leaks...
  31. pmc Intratumoral concentrations of imatinib after oral administration in patients with glioblastoma multiforme
    Matthias Holdhoff
    Brain Cancer Program, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Cancer Research Building II, Suite 1 M 16 1550 Orleans Street, Baltimore, MD, 21231, USA
    J Neurooncol 97:241-5. 2010
    ....
  32. ncbi Surgery insight: current management of epidural spinal cord compression from metastatic spine disease
    Timothy F Witham
    Department of Neurosurgery, at Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Nat Clin Pract Neurol 2:87-94; quiz 116. 2006
    ..Spinal stereotactic radiosurgery, vertebroplasty, and kyphoplasty, are emerging treatment options that are beginning to be used in selected patients with MESCC...
  33. ncbi Concomitant conus medullaris ependymoma and filum terminale lipoma: case report
    Gary L Gallia
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Neurosurgery 58:E1214; discussion E1214. 2006
    ..In this report, we describe the clinical presentation, radiographic findings, operative details, and pathological features of a patient with a conus medullaris ependymoma and a filum terminale lipoma...
  34. ncbi Robotic path planning for surgeon skill evaluation in minimally-invasive sinus surgery
    Narges Ahmidi
    Department of Computer Science, Johns Hopkins University, Baltimore, MD 21218, USA
    Med Image Comput Comput Assist Interv 15:471-8. 2012
    ..We also show that motions coded with DCC predict OSATS scores with 90% accuracy. Finally, the combination of SPP and DCC identifies surgical skill with 93% accuracy...
  35. pmc Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells
    Genevieve L Weber
    Ludwig Collaborative Laboratory, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Oncotarget 2:833-49. 2011
    ..We conclude that PIK3R1, like PIK3CA, is a potential therapeutic target in GBM and that it also influences tumor cell growth and motility...
  36. pmc Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme
    Ren Yuan Bai
    Ludwig Collaborative Laboratory, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    Neuro Oncol 13:974-82. 2011
    ..Our findings indicate that mebendazole is a possible novel anti-brain tumor therapeutic that could be further tested in clinical trials...
  37. pmc Frameless stereotaxy in a transmandibular, circumglossal, retropharyngeal cervical decompression in a Klippel-Feil patient: technical note
    Daniel M Sciubba
    Department on Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Eur Spine J 15:1286-91. 2006
    ..This technical note illustrates the previously undescribed, successful use of frameless stereotaxy to the transmandibular, circumglossal, retropharyngeal surgical approach in a patient with Klippel-Feil syndrome...
  38. pmc Podocalyxin-like protein is expressed in glioblastoma multiforme stem-like cells and is associated with poor outcome
    Zev A Binder
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America Johns Hopkins Physical Science Oncology Center and Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 8:e75945. 2013
    ..Moreover, high PODXL expression correlates with increasing glioma grade and decreased overall survival in patients with GBM. ..
  39. pmc Exomic sequencing of four rare central nervous system tumor types
    Chetan Bettegowda
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Oncotarget 4:572-83. 2013
    ..Our study supports the hypothesis that pathologically similar tumors arising in different age groups and from different compartments may represent distinct disease processes with varied genetic composition...
  40. doi Glioblastoma cell growth is suppressed by disruption of Fibroblast Growth Factor pathway signaling
    Watcharin Loilome
    Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, MD 21231, USA
    J Neurooncol 94:359-66. 2009
    ..Subsequent reduction in the cyclin D1, cyclin D2 and CDK4 cell cycle regulators was also observed. Our results indicate that FGF signaling pathway inhibition as a monotherapy will slow, but not arrest growth of glioblastoma cells...
  41. pmc Detection of circulating tumor DNA in early- and late-stage human malignancies
    Chetan Bettegowda
    Ludwig Center for Cancer Genetics and Therapeutics, Howard Hughes Medical Institute and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA
    Sci Transl Med 6:224ra24. 2014
    ..Together, these data suggest that ctDNA is a broadly applicable, sensitive, and specific biomarker that can be used for a variety of clinical and research purposes in patients with multiple different types of cancer. ..
  42. pmc Soft-tissue imaging with C-arm cone-beam CT using statistical reconstruction
    Adam S Wang
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA
    Phys Med Biol 59:1005-26. 2014
    ....
  43. pmc Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma
    Kaisorn L Chaichana
    Corresponding authors Kaisorn L Chaichana, MD, The Johns Hopkins Hospital, Department of Neurosurgery, Johns Hopkins University, 600 North Wolfe Street, Meyer 8 184, Baltimore, MD 21202 Alfredo Quiñones Hinojosa, MD, The Johns Hopkins Hospital, Department of Neurosurgery, Johns Hopkins University, Cancer Research Building II, 1550 Orleans Street, Room 247, Baltimore, MD 21231
    Neuro Oncol 16:113-22. 2014
    ..The goals were to evaluate whether there is an association between EOR and RV with survival and recurrence and to establish minimum EOR and maximum RV thresholds...
  44. pmc An integrated genomic analysis of human glioblastoma multiforme
    D Williams Parsons
    Ludwig Center for Cancer Genetics and Therapeutics, and Howard Hughes Medical Institute at Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21231, USA
    Science 321:1807-12. 2008
    ..These studies demonstrate the value of unbiased genomic analyses in the characterization of human brain cancer and identify a potentially useful genetic alteration for the classification and targeted therapy of GBMs...
  45. pmc 5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft
    Alexandra Borodovsky
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Oncotarget 4:1737-47. 2013
    ..These results have implications for clinical trials of demethylating agents for patients with IDH mutated gliomas. ..
  46. pmc Intraoperative C-arm cone-beam computed tomography: quantitative analysis of surgical performance in skull base surgery
    Stella Lee
    Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA
    Laryngoscope 122:1925-32. 2012
    ....
  47. doi A system for video-based navigation for endoscopic endonasal skull base surgery
    Daniel J Mirota
    Department of Computer Science, Johns Hopkins University, Baltimore, MD 21218, USA
    IEEE Trans Med Imaging 31:963-76. 2012
    ..These data are then used to update the current camera pose. We present a method for validation of our system, which achieves submillimeter (0.70 mm mean) target registration error (TRE) results...
  48. ncbi Regression of intracranial meningioma following intratumoral hemorrhage
    João Paulo C de Almeida
    Department of Neurosurgery, Johns Hopkins University, 600 North Wolfe Street, Meyer Building 8 161, Baltimore, Maryland 21287, USA
    J Clin Neurosci 16:1246-9. 2009
    ..We review the literature on hemorrhage in meningiomas and postulate some pathophysiologic mechanisms for the bleeding and subsequent tumor resolution seen in this patient...
  49. pmc Coexpression of neuronatin splice forms promotes medulloblastoma growth
    I Mei Siu
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21231 USA
    Neuro Oncol 10:716-24. 2008
    ..Our findings suggest that the frequently observed overexpression of both NNAT splice forms in MB enhances growth in this cancer...
  50. ncbi Clinical features of sellar and suprasellar meningiomas
    Ratchaneewan Kwancharoen
    Division of Endocrinology and Metabolism, Department of Medicine, Pituitary Center, Johns Hopkins University School of Medicine Baltimore, 1830 East Monument Street 333, Baltimore, MD, 21287, USA
    Pituitary 17:342-8. 2014
    ..The diagnosis is suggested by the radiologist in approximately 2/3 of the cases. An improved method to differentiate preoperatively these tumors from adenomas would be desirable. ..
  51. ncbi Rapamycin rescues ABT-737 efficacy in small cell lung cancer
    Eric E Gardner
    Authors Affiliations Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine Departments of Oncology and Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland and Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New YorkAuthors Affiliations Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine Departments of Oncology and Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland and Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York
    Cancer Res 74:2846-56. 2014
    ..These data have direct translational implications for SCLC clinical trials...
  52. doi Expanded endonasal endoscopic approach for resection of a large skull base aneurysmal bone cyst in a pediatric patient with extensive cranial fibrous dysplasia
    Vafi Salmasi
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Childs Nerv Syst 27:649-56. 2011
    ..This case adds to the growing body of evidence supporting a role for expanded endonasal endoscopic procedures in pediatric patients with skull base pathologies...
  53. doi Application of technology for minimally invasive neurosurgery
    Masaru Ishii
    Department of Otolaryngology, Head and Neck Surgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Neurosurg Clin N Am 21:585-94, v. 2010
    ..This article highlights current technologies for minimally invasive cranial neurosurgery...
  54. ncbi Intracranial aneurysm following radiation therapy during childhood for a brain tumor. Case report and review of the literature
    Daniel M Sciubba
    Department of Neurosurgery, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    J Neurosurg 105:134-9. 2006
    ..This case serves to remind clinicians of the possibility, albeit rare, that intracranial aneurysms may form following cranial radiotherapy...
  55. doi Expanded endonasal endoscopic approach for resection of a juvenile nasopharyngeal angiofibroma with skull base involvement
    Gary L Gallia
    Department of Neurosurgery and Oncology, Johns Hopkins Hospital, Phipps Building, Room 118, Baltimore, Maryland 21287, USA
    J Clin Neurosci 17:1423-7. 2010
    ..Additionally, we review the literature of endoscopic approaches to JNAs with skull base involvement...
  56. ncbi A novel rat model for the study of intraosseous metastatic spine cancer
    Ajay Mantha
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Neurosurg Spine 2:303-7. 2005
    ..In this study the authors describe the technique for creating an intraosseous spinal tumor model in rats and present a functional and histological analysis...
  57. ncbi Diethylstilbestrol (DES)-induced clear cell adenocarcinoma of the vagina metastasizing to the brain
    Li Mei Lin
    Department of Neurosurgery, Johns Hopkins School of Medicine, 600 North Wolfe Street, Meyer 8 161, Baltimore, MD 21287, USA
    Gynecol Oncol 105:273-6. 2007
    ..Vaginal CCA commonly metastasizes to the lungs and the supraclavicular lymph nodes; however we present a rare case of diethylstilbestrol-induced vaginal CCA with cerebral metastases...
  58. ncbi Synovial sarcoma of the frontal sinus. Case report
    Gary L Gallia
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Neurosurg 103:1077-80. 2005
    ..The authors present a case of synovial sarcoma arising from the frontal sinus and review the literature of synovial sarcomas arising from the paranasal sinuses...
  59. pmc Harvey Cushing's Approaches to Tumors in His Early Career: From the Skull Base to the Cranial Vault
    Courtney Pendleton
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
    Skull Base 21:271-6. 2011
    ..While Cushing's experience with selected skull base pathology has been previously reported, the breadth of his contributions to operative approaches to the skull base has been neglected...
  60. ncbi Local treatment of malignant brain tumors using implantable chemotherapeutic polymers
    Gary L Gallia
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Natl Compr Canc Netw 3:721-8. 2005
    ..In this article, we summarize these trials and discuss ongoing clinical trials involving implantable chemotherapy-containing polymers in the treatment of patients with malignant gliomas...
  61. ncbi Vertebral synovial chondromatosis. Report of two cases and review of the literature
    Gary L Gallia
    Departments of Neurosurgery, Pathology, and Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Neurosurg Spine 1:211-8. 2004
    ....