K K Koh

Summary

Affiliation: Gachon Medical School

Publications

  1. ncbi request reprint Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia
    Kwang Kon Koh
    Department of Cardiology, Gachon Medical School, Incheon, Korea
    J Am Coll Cardiol 45:1649-53. 2005
  2. ncbi request reprint The effects of simvastatin, losartan, and combined therapy on soluble CD40 ligand in hypercholesterolemic, hypertensive patients
    Seung Hwan Han
    Vascular Medicine and Atherosclerosis Unit, Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, South Korea
    Atherosclerosis 190:205-11. 2007
  3. pmc Leptin and cardiovascular disease: response to therapeutic interventions
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Division of Cardiology, Gachon University Gil Medical Center, 1198 Kuwol dong, Namdong gu, Incheon, South Korea 405 760
    Circulation 117:3238-49. 2008
  4. ncbi request reprint Inflammatory markers and the metabolic syndrome: insights from therapeutic interventions
    Kwang Kon Koh
    Division of Cardiology, Gil Heart Center, Gachon Medical School, Incheon, Korea
    J Am Coll Cardiol 46:1978-85. 2005
  5. ncbi request reprint Vascular effects of step I diet in hypercholesterolemic patients with coronary artery disease
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Department of Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon, Korea
    Am J Cardiol 92:708-10. 2003
  6. ncbi request reprint Should progestins be blamed for the failure of hormone replacement therapy to reduce cardiovascular events in randomized controlled trials?
    Kwang Kon Koh
    Division of Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon, Korea 405 760
    Arterioscler Thromb Vasc Biol 24:1171-9. 2004
  7. ncbi request reprint Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension
    Kwang Kon Koh
    Department of Cardiology, Vascular Medicine and Atherosclerosis Unit, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Korea
    Am J Cardiol 93:1432-5, A10. 2004
  8. ncbi request reprint Effects of conventional or lower doses of hormone replacement therapy in postmenopausal women
    Kwang Kon Koh
    Department of Cardiology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Arterioscler Thromb Vasc Biol 24:1516-21. 2004
  9. ncbi request reprint Simvastatin combined with ramipril treatment in hypercholesterolemic patients
    Kwang Kon Koh
    Department of Cardiology, Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon, Korea
    Hypertension 44:180-5. 2004
  10. ncbi request reprint Comparative effects of statin and fibrate on nitric oxide bioactivity and matrix metalloproteinase in hyperlipidemia
    Kwang Kon Koh
    Cardiology, Gachon Medical School, Incheon, South Korea
    Int J Cardiol 97:239-44. 2004

Collaborators

Detail Information

Publications65

  1. ncbi request reprint Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia
    Kwang Kon Koh
    Department of Cardiology, Gachon Medical School, Incheon, Korea
    J Am Coll Cardiol 45:1649-53. 2005
    ..We compared vascular and metabolic responses (and adverse responses) to statin and fibrate therapies alone or in combination in patients with combined hyperlipidemia...
  2. ncbi request reprint The effects of simvastatin, losartan, and combined therapy on soluble CD40 ligand in hypercholesterolemic, hypertensive patients
    Seung Hwan Han
    Vascular Medicine and Atherosclerosis Unit, Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, South Korea
    Atherosclerosis 190:205-11. 2007
    ..Simvastatin, losartan and combined therapy significantly reduced sCD40L to the greatest extent in patients with high baseline sCD40L levels...
  3. pmc Leptin and cardiovascular disease: response to therapeutic interventions
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Division of Cardiology, Gachon University Gil Medical Center, 1198 Kuwol dong, Namdong gu, Incheon, South Korea 405 760
    Circulation 117:3238-49. 2008
  4. ncbi request reprint Inflammatory markers and the metabolic syndrome: insights from therapeutic interventions
    Kwang Kon Koh
    Division of Cardiology, Gil Heart Center, Gachon Medical School, Incheon, Korea
    J Am Coll Cardiol 46:1978-85. 2005
    ....
  5. ncbi request reprint Vascular effects of step I diet in hypercholesterolemic patients with coronary artery disease
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Department of Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon, Korea
    Am J Cardiol 92:708-10. 2003
    ..Step I diet therapy improved endothelium-dependent vasodilation with an increase in plasma nitrogen oxide and a decrease in oxidant stress in hypercholesterolemic patients with coronary artery disease...
  6. ncbi request reprint Should progestins be blamed for the failure of hormone replacement therapy to reduce cardiovascular events in randomized controlled trials?
    Kwang Kon Koh
    Division of Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon, Korea 405 760
    Arterioscler Thromb Vasc Biol 24:1171-9. 2004
    ....
  7. ncbi request reprint Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension
    Kwang Kon Koh
    Department of Cardiology, Vascular Medicine and Atherosclerosis Unit, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Korea
    Am J Cardiol 93:1432-5, A10. 2004
    ..001 by ANOVA) with no differences between the 2, and only candesartan therapy significantly lowered plasma levels of monocyte chemoattractant protein-1 (p = 0.004 by ANOVA)...
  8. ncbi request reprint Effects of conventional or lower doses of hormone replacement therapy in postmenopausal women
    Kwang Kon Koh
    Department of Cardiology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Arterioscler Thromb Vasc Biol 24:1516-21. 2004
    ..In the current study, we compared the effects of lower doses of HRT (L-HRT) and conventional doses of HRT (C-HRT) on a variety of relevant cardiovascular parameters...
  9. ncbi request reprint Simvastatin combined with ramipril treatment in hypercholesterolemic patients
    Kwang Kon Koh
    Department of Cardiology, Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon, Korea
    Hypertension 44:180-5. 2004
    ..001 by ANOVA). Simvastatin combined with ramipril significantly improved endothelium-dependent vasodilation and fibrinolysis potential and reduced plasma levels of oxidant stress and inflammation markers in hypercholesterolemic patients...
  10. ncbi request reprint Comparative effects of statin and fibrate on nitric oxide bioactivity and matrix metalloproteinase in hyperlipidemia
    Kwang Kon Koh
    Cardiology, Gachon Medical School, Incheon, South Korea
    Int J Cardiol 97:239-44. 2004
    ..Because the lipoprotein effects of statin and fibric acid derivatives therapies differ, we studied the effects of these therapies in patients with hyperlipidemia on lipoproteins, vasomotor function, and plaque stability...
  11. ncbi request reprint Vascular effects of simvastatin combined with ramipril in hypercholesterolemic patients with coronary artery disease, compared with simvastatin alone: a randomized, double-blind, placebo-controlled, crossover study
    Kwang Kon Koh
    kVascular Medicine and Atherosclerosis Unit, Cardiology, Gil Heart Center, Gachon Medical School, Kuwol dong 1198, Namdong gu, Incheon 405 760, Korea
    Atherosclerosis 177:147-53. 2004
    ..However, simvastatin combined with ramipril did not significantly change, compared with simvastatin alone...
  12. ncbi request reprint Angiotensin II type 1 receptor blockers reduce tissue factor activity and plasminogen activator inhibitor type-1 antigen in hypertensive patients: a randomized, double-blind, placebo-controlled study
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Korea
    Atherosclerosis 177:155-60. 2004
    ..ARBs significantly reduced TF activity, PAI-1 antigen levels, and aldosterone levels in hypertensive patients. The clinical significance of the varying potency of some ARBs needs to be further investigated...
  13. ncbi request reprint Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients
    Kwang Kon Koh
    Cardiology, Vascular Medicine and Atherosclerosis Unit, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon, Korea
    Circulation 110:3687-92. 2004
    ..Therefore, we compared vascular and metabolic responses to these therapies either alone or in combination in hypercholesterolemic, hypertensive patients...
  14. ncbi request reprint Significant differential effects of lower doses of hormone therapy or tibolone on markers of cardiovascular disease in post-menopausal women: a randomized, double-blind, crossover study
    Kwang Kon Koh
    Division of Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Korea
    Eur Heart J 26:1362-8. 2005
    ..The objective was to compare the effects of L-HT and tibolone on lipid profile, vasodilation, and factors associated with inflammation and haemostasis...
  15. ncbi request reprint Vascular and metabolic effects of combined therapy with ramipril and simvastatin in patients with type 2 diabetes
    Kwang Kon Koh
    Department of Cardiology, Gachon Medical School, Incheon, Korea
    Hypertension 45:1088-93. 2005
    ..015 by ANOVA). Ramipril combined with simvastatin had beneficial vascular and metabolic effects when compared with monotherapy in patients with type 2 diabetes...
  16. ncbi request reprint Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Division of Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon, Korea 405 760
    Diabetes Care 28:1419-24. 2005
    ..We hypothesize fenofibrate improves endothelial function by enhancing insulin sensitivity...
  17. ncbi request reprint Anti-inflammatory and metabolic effects of candesartan in hypertensive patients
    Kwang Kon Koh
    Cardiology, Gachon Medical School, Incheon, South Korea
    Int J Cardiol 108:96-100. 2006
    ..The mechanisms of this benefit may relate to the ability of AT1 receptor blockers to reduce inflammation and insulin resistance...
  18. ncbi request reprint Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients
    Kwang Kon Koh
    Department of Cardiology, Vascular Medicine and Atherosclerosis Unit, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon, Korea 405 760
    J Am Coll Cardiol 42:905-10. 2003
    ..We investigated the vascular effects of candesartan in hypertensive patients...
  19. ncbi request reprint Significant differential effects of hormone therapy or tibolone on markers of cardiovascular disease in postmenopausal women: a randomized, double-blind, placebo-controlled, crossover study
    Kwang Kon Koh
    Division of Cardiology, Gil Heart Center, Gachon Medical School, Namdong gu, Incheon, Korea
    Arterioscler Thromb Vasc Biol 23:1889-94. 2003
    ..The objective was to compare the effects of tibolone and hormone therapy (HT) on lipid profile, vasodilation, and factors associated with inflammation and hemostasis...
  20. ncbi request reprint Comparative effects of diet and simvastatin on markers of thrombogenicity in patients with coronary artery disease
    Kwang Kon Koh
    Department of Cardiology, Gachon Medical School, Namdong gu, Incheon, South Korea
    Am J Cardiol 91:1231-4. 2003
  21. ncbi request reprint Non-lipid effects of statin on hypercholesterolemic patients established to have coronary artery disease who remained hypercholesterolemic while eating a step-II diet
    K K Koh
    Department of Cardiology, Gachon Medical School, Inchon, South Korea
    Coron Artery Dis 12:305-11. 2001
    ..The beneficial effects of statins on clinical events may involve nonlipid mechanisms that affect endothelial function, such as inflammatory responses, formation of thrombi, and stabilization of plaque...
  22. ncbi request reprint Effects of HMG-CoA reductase inhibitor on hemostasis
    K K Koh
    Division of Cardiology, Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, 405 760, Inchon, South Korea
    Int J Cardiol 76:23-32. 2000
    ..Thus, favorable effects of statins on hemostasis may be relevant to decreasing or delaying the progression and clinical manifestations of atherosclerosis...
  23. ncbi request reprint Effects of statins on vascular wall: vasomotor function, inflammation, and plaque stability
    K K Koh
    Heart Center, Division of Cardiology, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Inchon, 405 760 South Korea
    Cardiovasc Res 47:648-57. 2000
    ..Statins decrease the adhesion of monocyte to endothelial cells. Accordingly, statins exert their cardiovascular benefits through a direct antiatherogenic properties in the arterial wall, beyond their effects on plasma lipids...
  24. ncbi request reprint Vascular effects of estrogen in type II diabetic postmenopausal women
    K K Koh
    Department of Cardiology, Inchon, South Korea
    J Am Coll Cardiol 38:1409-15. 2001
    ..We assessed the effects of estrogen on vascular dilatory and other homeostatic functions potentially affected by nitric oxide (NO)-potentiating properties in type II diabetic postmenopausal women...
  25. ncbi request reprint Effects of estrogen on the vascular wall: vasomotor function and inflammation
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Division of Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, South Korea
    Cardiovasc Res 55:714-26. 2002
  26. ncbi request reprint Effects of continuous combined hormone replacement therapy on inflammation in hypertensive and/or overweight postmenopausal women
    Kwang Kon Koh
    Department of Cardiology, Gachon Medical School, Incheon, Korea
    Arterioscler Thromb Vasc Biol 22:1459-64. 2002
    ..We observed that estrogen did not show cardioprotective benefits in type 2 diabetic postmenopausal women. We hypothesized that hypertensive and/or overweight women may be less likely to realize cardiovascular benefits from estrogen...
  27. ncbi request reprint Effect of hormone replacement therapy on nitric oxide bioactivity and monocyte chemoattractant protein-1 levels
    K K Koh
    Cardiology, Gachon Medical School, Inchon, South Korea 405 760
    Int J Cardiol 81:43-50. 2001
    ..We investigated the effect of hormone replacement therapy (HRT) on vasomotor function and monocyte chemoattractant protein (MCP)-1 levels, an important serological marker of inflammation...
  28. ncbi request reprint Comparative effects of diet and statin on NO bioactivity and matrix metalloproteinases in hypercholesterolemic patients with coronary artery disease
    Kwang Kon Koh
    Department of Cardiology, Gachon Medical School, Incheon, Korea
    Arterioscler Thromb Vasc Biol 22:e19-23. 2002
    ..Furthermore, we investigated the mechanism of regulation suggested by experimental studies...
  29. ncbi request reprint Can a healthy endothelium influence the cardiovascular effects of hormone replacement therapy?
    Kwang Kon Koh
    Division of Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol Dong Namdong Gu, 405 760 Inchon, South Korea
    Int J Cardiol 87:1-8. 2003
    ..Therefore, optimizing the clinical benefits of these regimens in postmenopausal women depends largely on promoting a healthy endothelium through life-style modifications that diminish coronary risk...
  30. ncbi request reprint Vascular effects of synthetic or natural progestagen combined with conjugated equine estrogen in healthy postmenopausal women
    K K Koh
    Department of Cardiology, Menopause Clinic, Gachon Medical School, Inchon, Korea
    Circulation 103:1961-6. 2001
    ..Nonetheless, observational studies report no differences in risk for clinical cardiovascular events between users of unopposed estrogen and users of estrogen combined with synthetic progestin...
  31. ncbi request reprint Additive beneficial effects of fenofibrate combined with candesartan in the treatment of hypertriglyceridemic hypertensive patients
    Kwang Kon Koh
    Department of Cardiology, Laboratory Medicine, Gachon Medical School, Incheon, Korea
    Diabetes Care 29:195-201. 2006
    ..We investigated vascular and metabolic responses to these therapies either alone or in combination in hypertriglyceridemic hypertensive patients...
  32. ncbi request reprint Combined therapy with ramipril and simvastatin has beneficial additive effects on tissue factor activity and prothrombin fragment 1+2 in patients with type 2 diabetes
    Kwang Kon Koh
    Cardiology, Laboratory Medicine, Gachon Medical School, Incheon, Republic of Korea
    Atherosclerosis 194:230-7. 2007
    ..204 by ANOVA). Ramipril combined with simvastatin significantly reduces plasma TF activity and F1+2 levels to a greater extent than monotherapy with either drug in patients with type 2 diabetes...
  33. ncbi request reprint Vascular and metabolic effects of candesartan: insights from therapeutic interventions
    Kwang Kon Koh
    Division of Cardiology, Gil Heart Center, Gachon Medical School, Incheon, Korea
    J Hypertens Suppl 24:S31-8. 2006
    ..Hypertensive patients have impaired endothelial functions that have positive predictive power with respect to future cardiovascular events...
  34. doi request reprint Does reversal of oxidative stress and inflammation provide vascular protection?
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Division of Cardiology, Gachon University, Gil Medical Center, 1198 Kuwol dong, Namdong gu, Incheon 405 760, South Korea
    Cardiovasc Res 81:649-59. 2009
    ..Thus, combination therapy may be an important paradigm for treating and slowing progression of atherosclerosis, coronary heart disease, and co-morbid metabolic disorders characterized by endothelial dysfunction and insulin resistance...
  35. pmc Simvastatin improves flow-mediated dilation but reduces adiponectin levels and insulin sensitivity in hypercholesterolemic patients
    Kwang Kon Koh
    Divison of Cardiology, Gil Medical Center, Gachon University, Incheon, Korea
    Diabetes Care 31:776-82. 2008
    ..We hypothesized that simvastatin may reduce adiponectin levels and insulin sensitivity in hypercholesterolemic patients...
  36. pmc Distinct vascular and metabolic effects of different classes of anti-hypertensive drugs
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Cardiology, Gil Medical Center, Gachon University, Incheon, Republic of Korea
    Int J Cardiol 140:73-81. 2010
    ..This is not explained by changes in blood pressure alone. We hypothesized that distinct vascular and metabolic effects of anti-hypertensive drugs may explain these differential effects...
  37. pmc Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients
    Kwang Kon Koh
    Cardiology, Gil Medical Center, Gachon University, Incheon, Republic of Korea
    Atherosclerosis 204:483-90. 2009
    ..Therefore, we hypothesized that simvastatin and pravastatin may have differential metabolic effects in hypercholesterolemic patients...
  38. ncbi request reprint Controversies regarding hormone therapy: Insights from inflammation and hemostasis
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Division of Cardiology, Gil Medical Center, Gachon Medical School, Incheon, Korea
    Cardiovasc Res 70:22-30. 2006
    ..We also briefly discuss effects of lower doses of HT and tibolone in postmenopausal women...
  39. ncbi request reprint Additive beneficial cardiovascular and metabolic effects of combination therapy with ramipril and candesartan in hypertensive patients
    Kwang Kon Koh
    Cardiology, Gachon Medical School, Incheon, Korea
    Eur Heart J 28:1440-7. 2007
    ..Therefore, we hypothesized that combination therapy has additive beneficial effects to simultaneously improve endothelial dysfunction and adipocytokine profiles in patients with hypertension...
  40. doi request reprint Amlodipine improves endothelial function and metabolic parameters in patients with hypertension
    Kwang Kon Koh
    Gil Medical Center, Gachon University, Incheon, Korea
    Int J Cardiol 133:23-31. 2009
    ..We hypothesized that amlodipine therapy in hypertensive subjects will improve endothelial dysfunction and metabolic parameters...
  41. ncbi request reprint Effect of hormone replacement therapy on tissue factor activity, C-reactive protein, and the tissue factor pathway inhibitor
    Kwang Kon Koh
    Department of Cardiology, South Korea Gachon Medical School, Incheon, South Korea
    Am J Cardiol 91:371-3. 2003
  42. ncbi request reprint Statin attenuates increase in C-reactive protein during estrogen replacement therapy in postmenopausal women
    Kwang Kon Koh
    Gachon Medical College, Inchon, South Korea
    Circulation 105:1531-3. 2002
    ....
  43. ncbi request reprint Effects of statin on plaque stability and thrombogenicity in hypercholesterolemic patients with coronary artery disease
    Ji Won Son
    Cardiology, Gachon Medical School, Inchon, South Korea
    Int J Cardiol 88:77-82. 2003
    ..Experimental studies have shown that lipoproteins or mevalonate regulate matrix metalloproteinase (MMP)-9, tissue factor (TF), plasminogen activator inhibitor-1 (PAI-1) expression, providing nonlipid mechanism...
  44. ncbi request reprint Efficacy of heparin-coated stent in early setting of acute myocardial infarction
    E K Shin
    Division of Cardiology, Gachon University Gil Medical Center, Inchon, South Korea
    Catheter Cardiovasc Interv 52:306-12. 2001
    ..Angiographic restenosis rate compares favorably to the binary restenosis rate from other studies with uncoated stents...
  45. doi request reprint Antiatherosclerotic and anti-insulin resistance effects of adiponectin: basic and clinical studies
    Seung Hwan Han
    Division of Cardiology, Gachon University Gil Hospital, Incheon 405 760, Korea
    Prog Cardiovasc Dis 52:126-40. 2009
    ..The effects of lifestyle modifications and cardiovascular drugs on adiponectin levels and insulin resistance suggest plausible mechanisms that may be important for understanding and treating atherosclerosis and coronary heart disease...
  46. pmc Vascular and metabolic effects of treatment of combined hyperlipidemia: focus on statins and fibrates
    Kwang Kon Koh
    Division of Cardiology, Gil Heart Center, Gachon Medical School, Incheon, Republic of Korea
    Int J Cardiol 124:149-59. 2008
    ..When statins are combined with gemfibrozil therapy, this is more likely to be accompanied by myopathy. However, this limitation is not observed when fenofibrate, bezafibrate, or ciprofibrate are used in combination therapy...
  47. pmc Atorvastatin causes insulin resistance and increases ambient glycemia in hypercholesterolemic patients
    Kwang Kon Koh
    Department of Cardiology, Gachon University, Gil Medical Center, Incheon, Korea
    J Am Coll Cardiol 55:1209-16. 2010
    ..We investigated whether atorvastatin might decrease insulin sensitivity and increase ambient glycemia in hypercholesterolemic patients...
  48. ncbi request reprint Efonidipine simultaneously improves blood pressure, endothelial function, and metabolic parameters in nondiabetic patients with hypertension
    Kwang Kon Koh
    Department of Cardiology, Gil Heart Center, Gachon Medical School, Incheon, Korea
    Diabetes Care 30:1605-7. 2007
  49. pmc Combination therapy for treatment or prevention of atherosclerosis: focus on the lipid-RAAS interaction
    Kwang Kon Koh
    Division of Cardiology, Gachon University, Gil Medical Center, Incheon, Republic of Korea
    Atherosclerosis 209:307-13. 2010
    ....
  50. ncbi request reprint Vascular effects of diet and statin in hypercholesterolemic patients
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Division of Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, South Korea
    Int J Cardiol 95:185-91. 2004
    ....
  51. ncbi request reprint Effects of hormone replacement therapy on coagulation and fibrinolysis in postmenopausal women
    Kwang Kon Koh
    Gil Heart Center, Gachon Medical School, Incheon, Korea
    Int J Hematol 76:44-6. 2002
    ..However, HRT at conventional dosages improves fibrinolysis potential in healthy postmenopausal women...
  52. pmc Are statins effective for simultaneously treating dyslipidemias and hypertension?
    Kwang Kon Koh
    Vascular Medicine and Atherosclerosis Unit, Division of Cardiology, Gachon University, Gil Medical Center, 1198 Kuwol dong, Namdong gu, Incheon 405 760, South Korea
    Atherosclerosis 196:1-8. 2008
    ..However, based on published results from both small clinical studies and large randomized clinical trials, statins modestly lower blood pressure in patients with high, but not normal, blood pressure, regardless of cholesterol level...
  53. ncbi request reprint Beneficial vascular and metabolic effects of peroxisome proliferator-activated receptor-alpha activators
    Seung Hwan Han
    Division of Cardiology, Gil Heart Center, Gachon Medical School, Incheon, Korea
    Hypertension 46:1086-92. 2005
    ..In this review, we discuss the mechanisms underlying the vascular and metabolic effects of fibrates that may act synergistically to prevent or regress atherosclerosis and coronary heart disease...
  54. ncbi request reprint Reciprocal relationships between abnormal metabolic parameters and endothelial dysfunction
    Seung Hwan Han
    Division of Cardiology, Gachon Medical School, Incheon, South Korea
    Curr Opin Lipidol 18:58-65. 2007
    ..We review pathophysiological mechanisms underlying reciprocal relationships between endothelial dysfunction and insulin resistance and recent insights from therapeutic interventions to improve both metabolic and vascular function...
  55. ncbi request reprint Images in cardiovascular medicine. Neovascularization from coronary artery leaking to fungus ball in the lung
    Kwang Kon Koh
    Division of Cardiology, Gil Heart Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon, Korea 405 760
    Circulation 114:e551-2. 2006
  56. ncbi request reprint Adiponectin and cardiovascular disease: response to therapeutic interventions
    Seung Hwan Han
    Division of Cardiology, Gil Heart Center, Gachon Medical School, Incheon, Korea
    J Am Coll Cardiol 49:531-8. 2007
    ..The effects of lifestyle modifications and cardiovascular drugs on adiponectin levels and insulin resistance suggest plausible mechanisms that may be important for treating atherosclerosis and coronary heart disease...
  57. pmc Thrombosuction utilizing an export aspiration catheter during primary percutaneous coronary intervention in acute myocardial infarction
    Woong Chol Kang
    Division of Cardiology, Gil Medical Center, Gachon University of Medicine and Science, 1198 Kuwol dong, Namdong gu, Incheon, Korea
    Yonsei Med J 48:261-9. 2007
    ..We evaluated the efficacy of a thrombus reduction technique using an export aspiration catheter for thrombosuction during primary PCI...
  58. ncbi request reprint The union of vascular and metabolic actions of insulin in sickness and in health
    Jeong A Kim
    Arterioscler Thromb Vasc Biol 25:889-91. 2005
  59. ncbi request reprint Combination treatment to prevent atherosclerosis
    Kwang Kon Koh
    Hypertension 50:e67; author reply e68. 2007
  60. ncbi request reprint Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms
    Jeong A Kim
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, MD 20892 1632, USA
    Circulation 113:1888-904. 2006
    ..In the present review, we discuss pathophysiological mechanisms, including inflammatory processes, that couple endothelial dysfunction with insulin resistance and emphasize important therapeutic implications...
  61. doi request reprint Combination therapy for treatment or prevention of atherosclerosis
    Kwang Kon Koh
    Hypertension 52:e18; author reply e19. 2008
  62. ncbi request reprint Left anterior descending coronary artery myocardial bridging detected by 64-multidetector computed tomography
    Kwang Kon Koh
    Int J Cardiol 128:e62-4. 2008
    ..Coronary angiogram confirmed the middle third of the left anterior descending coronary artery myocardial bridging. Multidetector computed tomography is a reliable and noninvasive tool for diagnosing coronary myocardial bridging...
  63. ncbi request reprint Cardiovascular actions of insulin
    Ranganath Muniyappa
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892 1632, USA
    Endocr Rev 28:463-91. 2007
    ....
  64. ncbi request reprint Diffuse three-vessel coronary artery spasm
    Seung Hwan Han
    Int J Cardiol 102:161-4. 2005
    ..She performed an exercise test on Bruce protocol and exercised up to 11 min (13 METs) without chest pain. Following ergonovine provocation test, diffuse three-vessel coronary artery spasm was identified...
  65. ncbi request reprint Fenofibrate, statins, and inflammation
    Kwang Kon Koh
    Circ Res 98:e49. 2006