Benicio N Frey

Summary

Publications

  1. ncbi request reprint The role of hippocampus in the pathophysiology of bipolar disorder
    Benicio N Frey
    Bipolar Disorders Program and Laboratory of Molecular Psychiatry, Hospital de Clinicas de Porto Alegre, Rio Grande do Sul, Brazil
    Behav Pharmacol 18:419-30. 2007
  2. ncbi request reprint Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: an in vivo 1H MRS study
    Benicio N Frey
    MOOD CNS Program, Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, TX 78229, USA
    Bipolar Disord 9:119-27. 2007
  3. doi request reprint Neuronal correlates of brain-derived neurotrophic factor Val66Met polymorphism and morphometric abnormalities in bipolar disorder
    Koji Matsuo
    Department of Psychiatry, The University of Texas Health Science Center, San Antonio, TX, USA
    Neuropsychopharmacology 34:1904-13. 2009
  4. ncbi request reprint Effects of lithium and valproate on serum and hippocampal neurotrophin-3 levels in an animal model of mania
    Julio C Walz
    Bipolar Disorders Program, Centro de Pesquisas, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos, 2350, 90035 003 Porto Alegre, RS, Brazil
    J Psychiatr Res 42:416-21. 2008
  5. ncbi request reprint Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorder
    Benicio N Frey
    Department of Psychiatry, Psychiatric Genetics Research Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Neuroreport 18:1567-70. 2007
  6. ncbi request reprint Increased oxidative stress as a mechanism for decreased BDNF levels in acute manic episodes
    Flavio Kapczinski
    Bipolar Disorders Program and Laboratory of Molecular Psychiatry, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil
    Rev Bras Psiquiatr 30:243-5. 2008
  7. ncbi request reprint Increased serum glial cell line-derived neurotrophic factor immunocontent during manic and depressive episodes in individuals with bipolar disorder
    Adriane R Rosa
    Bipolar Disorders Program, Centro de Pesquisas, Hospital de Clinicas de Porto Alegre, and Department of Biochemistry, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    Neurosci Lett 407:146-50. 2006
  8. ncbi request reprint Celecoxib as an adjunct in the treatment of depressive or mixed episodes of bipolar disorder: a double-blind, randomized, placebo-controlled study
    Fabiano G Nery
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Hum Psychopharmacol 23:87-94. 2008
  9. pmc Effects of lithium and valproate on amphetamine-induced oxidative stress generation in an animal model of mania
    Benicio N Frey
    Departamento de Bioquimica, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul, and the Bipolar Disorders Program, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil
    J Psychiatry Neurosci 31:326-32. 2006
  10. ncbi request reprint Glial fibrillary acidic protein expression after electroconvulsive shocks in rat brain
    Keila M Ceresér
    Laboratorio de Psiquiatría Experimental, Centro de Pesquisas, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2350, 90035 003 Porto Alegre, RS, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 30:663-7. 2006

Collaborators

Detail Information

Publications12

  1. ncbi request reprint The role of hippocampus in the pathophysiology of bipolar disorder
    Benicio N Frey
    Bipolar Disorders Program and Laboratory of Molecular Psychiatry, Hospital de Clinicas de Porto Alegre, Rio Grande do Sul, Brazil
    Behav Pharmacol 18:419-30. 2007
    ..In conclusion, the available evidence suggests that the hippocampus plays an important role in the pathophysiology of BD...
  2. ncbi request reprint Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: an in vivo 1H MRS study
    Benicio N Frey
    MOOD CNS Program, Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, TX 78229, USA
    Bipolar Disord 9:119-27. 2007
    ..We hypothesized that BD subjects would present abnormal cellular metabolism within the DLPFC, as reflected by lower N-acetyl-aspartate (NAA) and creatine + phosphocreatine (Cr + PCr)...
  3. doi request reprint Neuronal correlates of brain-derived neurotrophic factor Val66Met polymorphism and morphometric abnormalities in bipolar disorder
    Koji Matsuo
    Department of Psychiatry, The University of Texas Health Science Center, San Antonio, TX, USA
    Neuropsychopharmacology 34:1904-13. 2009
    ....
  4. ncbi request reprint Effects of lithium and valproate on serum and hippocampal neurotrophin-3 levels in an animal model of mania
    Julio C Walz
    Bipolar Disorders Program, Centro de Pesquisas, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos, 2350, 90035 003 Porto Alegre, RS, Brazil
    J Psychiatr Res 42:416-21. 2008
    ..These results suggest that both Li and VPT modulate serum and central (hippocampal) NT-3 levels, and further support that the regulation of neurotrophic signaling systems may be related to the mechanisms of action of mood stabilizers...
  5. ncbi request reprint Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorder
    Benicio N Frey
    Department of Psychiatry, Psychiatric Genetics Research Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Neuroreport 18:1567-70. 2007
    ..These results indicate that bipolar disorder met-carriers have abnormal energy metabolism in the left dorsolateral prefrontal cortex...
  6. ncbi request reprint Increased oxidative stress as a mechanism for decreased BDNF levels in acute manic episodes
    Flavio Kapczinski
    Bipolar Disorders Program and Laboratory of Molecular Psychiatry, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil
    Rev Bras Psiquiatr 30:243-5. 2008
    ....
  7. ncbi request reprint Increased serum glial cell line-derived neurotrophic factor immunocontent during manic and depressive episodes in individuals with bipolar disorder
    Adriane R Rosa
    Bipolar Disorders Program, Centro de Pesquisas, Hospital de Clinicas de Porto Alegre, and Department of Biochemistry, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    Neurosci Lett 407:146-50. 2006
    ..These results further support the role of neurotrophins in the pathophysiology of bipolar disorder. Whether the observed increase in GDNF immunocontent correspond to a pathological or an adaptive response remains to be determined...
  8. ncbi request reprint Celecoxib as an adjunct in the treatment of depressive or mixed episodes of bipolar disorder: a double-blind, randomized, placebo-controlled study
    Fabiano G Nery
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Hum Psychopharmacol 23:87-94. 2008
    ..To investigate whether the cox-2 inhibitor celecoxib has antidepressant effects in bipolar disorder (BD) patients during depressive or mixed phases...
  9. pmc Effects of lithium and valproate on amphetamine-induced oxidative stress generation in an animal model of mania
    Benicio N Frey
    Departamento de Bioquimica, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul, and the Bipolar Disorders Program, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil
    J Psychiatry Neurosci 31:326-32. 2006
    ..We studied the effects of the mood stabilizers lithium and valproate on amphetamine-induced oxidative stress in an animal model of mania...
  10. ncbi request reprint Glial fibrillary acidic protein expression after electroconvulsive shocks in rat brain
    Keila M Ceresér
    Laboratorio de Psiquiatría Experimental, Centro de Pesquisas, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2350, 90035 003 Porto Alegre, RS, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 30:663-7. 2006
    ..The aim of the present study was to assess the effect of electroconvulsive shock (ECS) in glial fibrillary acidic protein (GFAP) expression in rat brain...
  11. ncbi request reprint Serum neurotrophin-3 is increased during manic and depressive episodes in bipolar disorder
    Julio C Walz
    Bipolar Disorders Program, Centro de Pesquisas, Hospital de Clinicas de Porto Alegre, and Department of Biochyemistry, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    Neurosci Lett 415:87-9. 2007
    ..001) and depressed (p<0.001) BD patients, as compared with euthymic patients and normal controls. These findings suggest that the NT-3 signaling system may play a role in the pathophysiology of BD...
  12. doi request reprint Allostatic load in bipolar disorder: implications for pathophysiology and treatment
    Flavio Kapczinski
    Bipolar Disorders Program and Laboratory of Molecular Psychiatry, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos 2350, 90035 000, Porto Alegre, RS, Brazil
    Neurosci Biobehav Rev 32:675-92. 2008
    ....