Stephen B Freedman

Summary

Publications

  1. pmc Impact of emergency department probiotic treatment of pediatric gastroenteritis: study protocol for the PROGUT (Probiotic Regimen for Outpatient Gastroenteritis Utility of Treatment) randomized controlled trial
    Stephen B Freedman
    Sections of Paediatric Emergency Medicine and Gastroenterology, Alberta Children s Hospital, Alberta Children s Hospital Research Institute, University of Calgary, 2888 Shaganappi Trail NW, Calgary, AB T3B 6A8, Canada
    Trials 15:170. 2014
  2. doi request reprint Pediatric abdominal radiograph use, constipation, and significant misdiagnoses
    Stephen B Freedman
    Divisions of Pediatric Emergency Medicine and Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Hospital for Sick Children, and Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Faculty of Medicine, University of Toronto, Toronto, ON Electronic address
    J Pediatr 164:83-88.e2. 2014
  3. doi request reprint Treatment of acute gastroenteritis in children: an overview of systematic reviews of interventions commonly used in developed countries
    Stephen B Freedman
    Sections of Pediatric Emergency Medicine and Gastroenterology, Alberta Children s Hospital, Alberta Children s Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada
    Evid Based Child Health 8:1123-37. 2013
  4. doi request reprint Bolus fluid therapy and sodium homeostasis in paediatric gastroenteritis
    Stephen B Freedman
    Sections of Emergency Medicine and Gastroenterology, Department of Paediatrics, Alberta Children s Hospital, Alberta, Canada
    J Paediatr Child Health 49:215-22. 2013
  5. doi request reprint Health care provider and caregiver preferences regarding nasogastric and intravenous rehydration
    Stephen B Freedman
    Divisions of aPediatric Emergency Medicine, Hospital for Sick Children Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatrics 130:e1504-11. 2012
  6. doi request reprint Time-series analysis of ondansetron use in pediatric gastroenteritis
    Stephen B Freedman
    The Hospital for Sick Children, The University of Toronto, Toronto, Canada
    J Pediatr Gastroenterol Nutr 54:381-6. 2012
  7. ncbi request reprint Emergency department revisits in children with gastroenteritis
    Stephen B Freedman
    Sections of Pediatric Emergency Medicine Gastroenterology, Alberta Children s Hospital Research Institute, University of Calgary, Calgary, Alberta Divisions of Paediatric Emergency Medicine and Child Health Evaluative Sciences, The Hospital for Sick Children Biostatistics Department, University Health Network Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada
    J Pediatr Gastroenterol Nutr 57:612-8. 2013
  8. pmc Rapid versus standard intravenous rehydration in paediatric gastroenteritis: pragmatic blinded randomised clinical trial
    Stephen B Freedman
    Division of Paediatric Emergency Medicine, Hospital for Sick Children, Toronto, ON, Canada
    BMJ 343:d6976. 2011
  9. doi request reprint The treatment of pediatric gastroenteritis: a comparative analysis of pediatric emergency physicians' practice patterns
    Stephen B Freedman
    Division of Pediatric Emergency Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Acad Emerg Med 18:38-45. 2011
  10. doi request reprint Prospective assessment of practice pattern variations in the treatment of pediatric gastroenteritis
    Stephen B Freedman
    Division of Pediatric Emergency Medicine, Hospital for Sick Children, University of Toronto, Toronto, Canada
    Pediatrics 127:e287-95. 2011

Detail Information

Publications32

  1. pmc Impact of emergency department probiotic treatment of pediatric gastroenteritis: study protocol for the PROGUT (Probiotic Regimen for Outpatient Gastroenteritis Utility of Treatment) randomized controlled trial
    Stephen B Freedman
    Sections of Paediatric Emergency Medicine and Gastroenterology, Alberta Children s Hospital, Alberta Children s Hospital Research Institute, University of Calgary, 2888 Shaganappi Trail NW, Calgary, AB T3B 6A8, Canada
    Trials 15:170. 2014
    ..Although clinical trials in children with gastroenteritis have been performed, most have significant flaws, and guidelines do not consistently endorse their use...
  2. doi request reprint Pediatric abdominal radiograph use, constipation, and significant misdiagnoses
    Stephen B Freedman
    Divisions of Pediatric Emergency Medicine and Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Hospital for Sick Children, and Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Faculty of Medicine, University of Toronto, Toronto, ON Electronic address
    J Pediatr 164:83-88.e2. 2014
    ....
  3. doi request reprint Treatment of acute gastroenteritis in children: an overview of systematic reviews of interventions commonly used in developed countries
    Stephen B Freedman
    Sections of Pediatric Emergency Medicine and Gastroenterology, Alberta Children s Hospital, Alberta Children s Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada
    Evid Based Child Health 8:1123-37. 2013
    ..Acute gastroenteritis (AGE) is an extremely common paediatric condition, which results in significant morbidity in children and is a financial burden to the society...
  4. doi request reprint Bolus fluid therapy and sodium homeostasis in paediatric gastroenteritis
    Stephen B Freedman
    Sections of Emergency Medicine and Gastroenterology, Department of Paediatrics, Alberta Children s Hospital, Alberta, Canada
    J Paediatr Child Health 49:215-22. 2013
    ..The study aims to assess the risk of developing hyponatraemia when large-volume bolus fluid rehydration therapy is administered...
  5. doi request reprint Health care provider and caregiver preferences regarding nasogastric and intravenous rehydration
    Stephen B Freedman
    Divisions of aPediatric Emergency Medicine, Hospital for Sick Children Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatrics 130:e1504-11. 2012
    ..Despite evidence supporting its use, nasogastric rehydration is rarely used in North America. We conducted a prospective, cross-sectional, 3-phase study to evaluate current perspectives...
  6. doi request reprint Time-series analysis of ondansetron use in pediatric gastroenteritis
    Stephen B Freedman
    The Hospital for Sick Children, The University of Toronto, Toronto, Canada
    J Pediatr Gastroenterol Nutr 54:381-6. 2012
    ..We aimed to determine whether increasing ondansetron usage is associated with improved outcomes in children with gastroenteritis...
  7. ncbi request reprint Emergency department revisits in children with gastroenteritis
    Stephen B Freedman
    Sections of Pediatric Emergency Medicine Gastroenterology, Alberta Children s Hospital Research Institute, University of Calgary, Calgary, Alberta Divisions of Paediatric Emergency Medicine and Child Health Evaluative Sciences, The Hospital for Sick Children Biostatistics Department, University Health Network Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada
    J Pediatr Gastroenterol Nutr 57:612-8. 2013
    ..The aim of the study was to determine whether intravenous fluid administration is independently associated with a reduction in unscheduled emergency department (ED) revisits within 7 days...
  8. pmc Rapid versus standard intravenous rehydration in paediatric gastroenteritis: pragmatic blinded randomised clinical trial
    Stephen B Freedman
    Division of Paediatric Emergency Medicine, Hospital for Sick Children, Toronto, ON, Canada
    BMJ 343:d6976. 2011
    ..To determine if rapid rather than standard intravenous rehydration results in improved hydration and clinical outcomes when administered to children with gastroenteritis...
  9. doi request reprint The treatment of pediatric gastroenteritis: a comparative analysis of pediatric emergency physicians' practice patterns
    Stephen B Freedman
    Division of Pediatric Emergency Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Acad Emerg Med 18:38-45. 2011
    ..This study sought to describe the ED treatments administered to children with acute gastroenteritis and to compare management between Canadian and U.S. physicians practicing pediatric emergency medicine (PEM)...
  10. doi request reprint Prospective assessment of practice pattern variations in the treatment of pediatric gastroenteritis
    Stephen B Freedman
    Division of Pediatric Emergency Medicine, Hospital for Sick Children, University of Toronto, Toronto, Canada
    Pediatrics 127:e287-95. 2011
    ....
  11. ncbi request reprint Impact of increasing ondansetron use on clinical outcomes in children with gastroenteritis
    Stephen B Freedman
    Sections of Emergency Medicine and Gastroenterology, Department of Pediatrics, Alberta Children s Hospital and Research Institute, University of Calgary, Calgary, Alberta
    JAMA Pediatr 168:321-9. 2014
    ..Ondansetron hydrochloride use in children with gastroenteritis is increasing rapidly; however, little is known about its impact on outcomes...
  12. doi request reprint Evaluation of a clinical dehydration scale in children requiring intravenous rehydration
    Laura M Kinlin
    Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Pediatrics 129:e1211-9. 2012
    ..To evaluate the reliability and validity of a previously derived clinical dehydration scale (CDS) in a cohort of children with gastroenteritis and evidence of dehydration...
  13. doi request reprint Ondansetron dosing in pediatric gastroenteritis: a prospective cohort, dose-response study
    Stephen B Freedman
    Division of Pediatric Emergency Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Paediatr Drugs 12:405-10. 2010
    ..Ondansetron is increasingly used to prevent emesis in children with acute gastroenteritis; however, the optimal dose is unknown...
  14. pmc Validation of the modified Vesikari score in children with gastroenteritis in 5 US emergency departments
    David Schnadower
    Division of Pediatric Emergency Medicine Division of Gastroenterology, Hepatology, and Nutrition, Washington University School of Medicine in St Louis, St Louis, MO Division of Pediatric Emergency Medicine, Medical College of Wisconsin, Milwaukee, WI Division of Pediatric Emergency Medicine, Children s National Medical Center, Washington DC Division of Pediatric Emergency Medicine, Columbia University College of Physician and Surgeons, New York, NY Division of Pediatric Emergency Medicine, Northwestern Feinberg School of Medicine, Chicago, IL Division of Pediatric Emergency Medicine, Wayne State School of Medicine, Detroit, MI Division of Pediatric Emergency Medicine, Cincinnati Children s Hospital, Cincinnati, OH Sections of Paediatric Emergency Medicine and Gastroenterology, Alberta Children s Hospital, Alberta Children s Hospital Research Institute, University of Calgary, Calgary, Canada
    J Pediatr Gastroenterol Nutr 57:514-9. 2013
    ..We sought to evaluate, in a US cohort, the reliability, construct validity, and generalizability of a gastroenteritis severity scale previously derived in a Canadian population, the modified Vesikari score (MVS)...
  15. doi request reprint North American practice patterns of intravenous magnesium therapy in severe acute asthma in children
    Suzanne Schuh
    The Hospital for Sick Children, University of Toronto, Ontario, Canada
    Acad Emerg Med 17:1189-96. 2010
    ....
  16. ncbi request reprint Evaluation of a gastroenteritis severity score for use in outpatient settings
    Stephen B Freedman
    MDCM, MSc, FRCPC, FAAP, Hospital for Sick Children, Division of Pediatric Emergency Medicine, 555 University Ave, Toronto, ON M5G 1X8, Canada
    Pediatrics 125:e1278-85. 2010
    ....
  17. ncbi request reprint Oral ondansetron for gastroenteritis in a pediatric emergency department
    Stephen B Freedman
    Division of Pediatric Emergency Medicine, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    N Engl J Med 354:1698-705. 2006
    ..We conducted a double-blind trial to determine whether a single oral dose of ondansetron, an antiemetic, would improve outcomes in children with gastroenteritis...
  18. ncbi request reprint The crying infant: diagnostic testing and frequency of serious underlying disease
    Stephen B Freedman
    Hospital for Sick Children, Division of Pediatric Emergency Medicine, 555 University Ave, Toronto, Ontario, Canada
    Pediatrics 123:841-8. 2009
    ..Secondary outcomes included the individual contributions of history, physical examination, and laboratory investigations in determining a diagnosis...
  19. ncbi request reprint Acute infectious pediatric gastroenteritis: beyond oral rehydration therapy
    Stephen B Freedman
    University of Toronto, Division of Pediatric Emergency Medicine, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
    Expert Opin Pharmacother 8:1651-65. 2007
    ..Finally, more aggressive intravenous rehydration strategies are being employed; however, at present, limited data from randomized clinical trials are available to support its routine use...
  20. doi request reprint Assessing the palatability of oral rehydration solutions in school-aged children: a randomized crossover trial
    Stephen B Freedman
    The Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON M5G 1X8, Canada
    Arch Pediatr Adolesc Med 164:696-702. 2010
    ..To compare the palatability of 3 oral rehydration solutions...
  21. ncbi request reprint Radiation exposure from imaging tests in pediatric emergency medicine: a survey of physician knowledge and risk disclosure practices
    Kathy Boutis
    Division of Emergency Medicine, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
    J Emerg Med 47:36-44. 2014
    ..Disclosing potential future malignancy risks from diagnostic tests that expose children to ionizing radiation in the emergency department may be challenging...
  22. ncbi request reprint Ondansetron and the risk of cardiac arrhythmias: a systematic review and postmarketing analysis
    Stephen B Freedman
    Sections of Pediatric Emergency Medicine and Gastroenterology, Alberta Children s Hospital, Alberta Children s Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada
    Ann Emerg Med 64:19-25.e6. 2014
    ..To explore the risk of cardiac arrhythmias associated with ondansetron administration in the context of recent recommendations for identification of high-risk individuals...
  23. doi request reprint Development of a Caregiver Gastroenteritis Knowledge Questionnaire
    Stephen B Freedman
    Department of Pediatrics, Division of Pediatric Emergency Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Ambul Pediatr 8:261-5. 2008
    ....
  24. doi request reprint The implementation of a gastroenteritis education program
    Stephen B Freedman
    Division of Paediatric Emergency Medicine, Department of Paediatrics, The Hospital for Sick Children, The University of Toronto, Toronto, ON, Canada M5G 1X8
    Am J Emerg Med 29:271-7. 2011
    ..The objective of this study is to determine if intensive gastroenteritis education results in greater caregiver knowledge and a reduction in future emergency department (ED) visits...
  25. ncbi request reprint Predictors of outcomes in pediatric enteritis: a prospective cohort study
    Stephen B Freedman
    Division of Pediatric Emergency Medicine, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Pediatrics 123:e9-16. 2009
    ..To guide management, we hypothesized that clinical variables available at the initial assessment could be identified that will predict the need for intravenous fluid administration...
  26. doi request reprint Waiver of informed consent in pediatric resuscitation research: a systematic review
    Mohamed Eltorki
    Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Acad Emerg Med 20:822-34. 2013
    ..Our review focused both on opinions and on the ability to conduct research without informed consent in life-threatening situations...
  27. ncbi request reprint Pediatric myocarditis: emergency department clinical findings and diagnostic evaluation
    Stephen B Freedman
    Division of Pediatric Emergency Medicine, Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
    Pediatrics 120:1278-85. 2007
    ..The goal was to determine, in children with myocarditis, the frequency of various presenting symptoms and the sensitivity of clinical and laboratory investigations routinely available in the emergency department...
  28. doi request reprint Parental knowledge of potential cancer risks from exposure to computed tomography
    Kathy Boutis
    Division of Emergency Medicine, Department of Pediatrics, The Hospital for Sick Children, and University of Toronto, Toronto, Canada
    Pediatrics 132:305-11. 2013
    ..We also examined willingness to proceed with recommended CT after risk disclosure and preference to be informed of potential risks...
  29. doi request reprint Predictors of clinically significant upper gastrointestinal hemorrhage among children with hematemesis
    Stephen B Freedman
    Division of Paediatric Emergency Medicine, The Hospital for Sick Children, Toronto, ON, Canada
    J Pediatr Gastroenterol Nutr 54:737-43. 2012
    ..The aim of the study was to determine the proportion of children with hematemesis who experience a clinically significant upper gastrointestinal hemorrhage (UGIH) and to identify variables predicting their occurrence...
  30. doi request reprint Pediatric cellulitis: success of emergency department short-course intravenous antibiotics
    April J Kam
    Division of Paediatric Emergency Medicine, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Pediatr Emerg Care 26:171-6. 2010
    ..The objective of this study was to determine the failure rate of ED short-course IV antibiotic therapy (IV-short course)...
  31. ncbi request reprint Easing the strain on a pediatric tertiary care center: use of a redistribution system
    Stephen B Freedman
    Division of Paediatric Emergency Medicine, Department of Paediatrics, The Hospital for Sick Children, Toronto, Canada
    Arch Pediatr Adolesc Med 161:870-6. 2007
    ..To evaluate the ability of a regionalized system to safely transfer patients requiring admission from a referral center to either regional or community hospitals...
  32. doi request reprint Successful discharge of children with gastroenteritis requiring intravenous rehydration
    Stephen B Freedman
    Division of Paediatric Emergency Medicine and Division of Gastroenterology, Hepatology and Nutrition, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Emerg Med 46:9-20. 2014
    ..Emergency Department (ED) revisits are very common in children with gastroenteritis administered intravenous rehydration...