Simon Fredriksson

Summary

Publications

  1. ncbi request reprint A sensitive proximity ligation assay for active PSA
    Lei Zhu
    Department of Clinical Chemistry, Biomedicum Helsinki University Central Hospital, FI 00029 Helsinki, Finland
    Biol Chem 387:769-72. 2006
  2. pmc Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals
    Stine Buch Thorsen
    Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Strandboulevarden 49, DK 2100, Copenhagen, Denmark
    J Transl Med 11:253. 2013
  3. pmc Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study
    Stine B Thorsen
    Institute of Veterinary Disease Biology and Sino Danish Breast Cancer Research Centre, Faculty of Health and Medical Sciences, University of Copenhagen, Strandboulevarden 49, DK 2100 Copenhagen, Denmark
    BMC Cancer 13:598. 2013
  4. pmc Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood
    Martin Lundberg
    Olink Bioscience, Uppsala Science Park, 75183 Uppsala, Sweden
    Nucleic Acids Res 39:e102. 2011
  5. ncbi request reprint Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer
    Simon Fredriksson
    Stanford Genome Technology Center, Bio X, Stanford University, Stanford, CA, USA
    Clin Chem 54:582-9. 2008
  6. ncbi request reprint Multiplexed protein detection by proximity ligation for cancer biomarker validation
    Simon Fredriksson
    Stanford Genome Technology Center, Stanford, California 94305, USA
    Nat Methods 4:327-9. 2007
  7. pmc Multigene amplification and massively parallel sequencing for cancer mutation discovery
    Fredrik Dahl
    Stanford Genome Technology Center, Stanford University, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 104:9387-92. 2007
  8. pmc Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability
    Erika Assarsson
    Olink Bioscience, Uppsala, Sweden
    PLoS ONE 9:e95192. 2014
  9. pmc Multiplex amplification of all coding sequences within 10 cancer genes by Gene-Collector
    Simon Fredriksson
    Stanford Genome Technology Center, Bio X, Stanford, California 94305, USA
    Nucleic Acids Res 35:e47. 2007
  10. ncbi request reprint Proximity ligation assays for sensitive and specific protein analyses
    Sigrun M Gustafsdottir
    Rudbeck Laboratory, Department of Genetics and Pathology, Uppsala University, SE 75185 Uppsala, Sweden
    Anal Biochem 345:2-9. 2005

Collaborators

  • Hanlee Ji
  • Fredrik Dahl
  • Albert Koong
  • Mats Nilsson
  • Odd Terje Brustugun
  • Michael Zhang
  • Johan Stenberg
  • Martin Lundberg
  • Erika Assarsson
  • Jan Stenvang
  • Stine B Thorsen
  • Nick Gee
  • Stine Buch Thorsen
  • Nils Brunner
  • Mick Knowles
  • Anna Eriksson
  • Mats Gullberg
  • Lei Zhu
  • Edith Schallmeiner
  • Ulf Landegren
  • Sigrun M Gustafsdottir
  • Johan Björkesten
  • Patrik Lindstedt
  • Emma Rennel Dickens
  • Sandra Ohlsson
  • Daniel Ekman
  • Stine Bucht Thorsen
  • Göran Holmquist
  • Ann Catrin Andersson
  • Gabriella Edfeldt
  • Anne Sofie Schrohl
  • Sidse O Würtz
  • Lena Vinther
  • Sarah Louise T Christensen
  • Birgitte S Nielsen
  • Ib Jarle Christensen
  • Sarah Lt Christensen
  • Hans Jørgen Nielsen
  • Andrea Villablanca
  • Birgitte Sander Nielsen
  • Kirstine Christensen Belling
  • Susanne Møller
  • Bonnie Tran
  • Ale Närvänen
  • Ping Wu
  • Ulf Hakan Stenman
  • Hannu Koistinen
  • Mathias Howell
  • Malin Jarvius
  • Jonas Jarvius
  • Ola Söderberg

Detail Information

Publications10

  1. ncbi request reprint A sensitive proximity ligation assay for active PSA
    Lei Zhu
    Department of Clinical Chemistry, Biomedicum Helsinki University Central Hospital, FI 00029 Helsinki, Finland
    Biol Chem 387:769-72. 2006
    ..Our results show that a highly sensitive immunopeptidometric assay can be developed using proximity ligation. This principle should facilitate establishment of specific assays for active forms of other proteases...
  2. pmc Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals
    Stine Buch Thorsen
    Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Strandboulevarden 49, DK 2100, Copenhagen, Denmark
    J Transl Med 11:253. 2013
    ....
  3. pmc Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study
    Stine B Thorsen
    Institute of Veterinary Disease Biology and Sino Danish Breast Cancer Research Centre, Faculty of Health and Medical Sciences, University of Copenhagen, Strandboulevarden 49, DK 2100 Copenhagen, Denmark
    BMC Cancer 13:598. 2013
    ..To pursue additional prognostic information from MMP-9 and TIMP-1, the level of the MMP-9 and TIMP-1 complex (MMP-9:TIMP-1) was investigated in plasma from breast cancer patients...
  4. pmc Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood
    Martin Lundberg
    Olink Bioscience, Uppsala Science Park, 75183 Uppsala, Sweden
    Nucleic Acids Res 39:e102. 2011
    ..Assay performance was also confirmed for a multiplex version of PEA...
  5. ncbi request reprint Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer
    Simon Fredriksson
    Stanford Genome Technology Center, Bio X, Stanford University, Stanford, CA, USA
    Clin Chem 54:582-9. 2008
    ..Sensitive methods are needed for biomarker discovery and validation. We tested one promising technology, multiplex proximity ligation assay (PLA), in a pilot study profiling plasma biomarkers in pancreatic and ovarian cancer...
  6. ncbi request reprint Multiplexed protein detection by proximity ligation for cancer biomarker validation
    Simon Fredriksson
    Stanford Genome Technology Center, Stanford, California 94305, USA
    Nat Methods 4:327-9. 2007
    ..The procedure can use a single polyclonal antibody batch for each target protein, simplifying affinity-reagent creation for new biomarker candidates...
  7. pmc Multigene amplification and massively parallel sequencing for cancer mutation discovery
    Fredrik Dahl
    Stanford Genome Technology Center, Stanford University, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 104:9387-92. 2007
    ..Seven cancer cell lines and one normal genomic DNA sample were studied with multiple mutations and polymorphisms identified among the 10 genes. Mutations and polymorphisms in the TP53 gene were confirmed by traditional sequencing...
  8. pmc Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability
    Erika Assarsson
    Olink Bioscience, Uppsala, Sweden
    PLoS ONE 9:e95192. 2014
    ..All-in-all, the development of the current multiplex technique is a step toward robust high throughput protein marker discovery and research. ..
  9. pmc Multiplex amplification of all coding sequences within 10 cancer genes by Gene-Collector
    Simon Fredriksson
    Stanford Genome Technology Center, Bio X, Stanford, California 94305, USA
    Nucleic Acids Res 35:e47. 2007
    ..Gene-Collector has utility for numerous applications such as high throughput resequencing, SNP analyses, and pathogen detection...
  10. ncbi request reprint Proximity ligation assays for sensitive and specific protein analyses
    Sigrun M Gustafsdottir
    Rudbeck Laboratory, Department of Genetics and Pathology, Uppsala University, SE 75185 Uppsala, Sweden
    Anal Biochem 345:2-9. 2005