Roger M Francis

Summary

Publications

  1. ncbi request reprint Back pain in osteoporotic vertebral fractures
    R M Francis
    School of Clinical Medical Sciences, University of Newcastle, Newcastle upon Tyne, UK
    Osteoporos Int 19:895-903. 2008
  2. ncbi request reprint What do we currently know about nutrition and bone health in relation to United Kingdom public health policy with particular reference to calcium and vitamin D?
    R M Francis
    Musculoskeletal Unit, Freeman Hospital, University of Newcastle upon Tyne, Newcastle upon Tyne, NE7 7DN, UK
    Br J Nutr 99:155-9. 2008
  3. ncbi request reprint The effects of testosterone on osteoporosis in men
    R M Francis
    Musculoskeletal Unit, Freeman Hospital, Newcastle upon Tyne, UK
    Clin Endocrinol (Oxf) 50:411-4. 1999
  4. ncbi request reprint Calcium, vitamin D and involutional osteoporosis
    Roger M Francis
    University of Newcastle upon Tyne, Musculoskeletal Unit, Freeman Hospital, Newcastle upon Tyne, UK
    Curr Opin Clin Nutr Metab Care 9:13-7. 2006
  5. ncbi request reprint Calcium and vitamin D in the prevention of osteoporotic fractures
    R M Francis
    School of Clinical Medical Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE7 7DN
    QJM 99:355-63. 2006
  6. ncbi request reprint Calcium and vitamin D in osteoporosis: chairman's introduction to proceedings
    R M Francis
    Musculoskeletal Unit, Freeman Hospital, University of Newcastle upon Tyne, Newcastle upon Tyne, NE7 7DN, UK
    Calcif Tissue Int 70:69. 2002
  7. ncbi request reprint Acute and long-term management of patients with vertebral fractures
    R M Francis
    Department of Medicine Geriatrics, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    QJM 97:63-74. 2004
  8. doi request reprint The prevalence of osteoporosis in patients with severe hip and knee osteoarthritis awaiting joint arthroplasty
    Elizabeth A Lingard
    Department of Orthopaedic Surgery, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK
    Age Ageing 39:234-9. 2010
  9. ncbi request reprint Mutifactorial analysis of risk factors for reduced bone mineral density in patients with Crohn's disease
    Sarah A Bartram
    Department of Medicine, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, United Kingdom
    World J Gastroenterol 12:5680-6. 2006
  10. ncbi request reprint Self-report overestimates true height loss: implications for diagnosis of osteoporosis
    Fraser Birrell
    Department of Rheumatology, University of Newcastle upon Tyne, 4th Floor, Cookson Building, UK
    Clin Rheumatol 24:590-2. 2005

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Back pain in osteoporotic vertebral fractures
    R M Francis
    School of Clinical Medical Sciences, University of Newcastle, Newcastle upon Tyne, UK
    Osteoporos Int 19:895-903. 2008
    ....
  2. ncbi request reprint What do we currently know about nutrition and bone health in relation to United Kingdom public health policy with particular reference to calcium and vitamin D?
    R M Francis
    Musculoskeletal Unit, Freeman Hospital, University of Newcastle upon Tyne, Newcastle upon Tyne, NE7 7DN, UK
    Br J Nutr 99:155-9. 2008
    ....
  3. ncbi request reprint The effects of testosterone on osteoporosis in men
    R M Francis
    Musculoskeletal Unit, Freeman Hospital, Newcastle upon Tyne, UK
    Clin Endocrinol (Oxf) 50:411-4. 1999
    ..Further studies are required to confirm the safety and efficacy of this treatment in eugonadal men with osteoporosis...
  4. ncbi request reprint Calcium, vitamin D and involutional osteoporosis
    Roger M Francis
    University of Newcastle upon Tyne, Musculoskeletal Unit, Freeman Hospital, Newcastle upon Tyne, UK
    Curr Opin Clin Nutr Metab Care 9:13-7. 2006
    ....
  5. ncbi request reprint Calcium and vitamin D in the prevention of osteoporotic fractures
    R M Francis
    School of Clinical Medical Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE7 7DN
    QJM 99:355-63. 2006
  6. ncbi request reprint Calcium and vitamin D in osteoporosis: chairman's introduction to proceedings
    R M Francis
    Musculoskeletal Unit, Freeman Hospital, University of Newcastle upon Tyne, Newcastle upon Tyne, NE7 7DN, UK
    Calcif Tissue Int 70:69. 2002
  7. ncbi request reprint Acute and long-term management of patients with vertebral fractures
    R M Francis
    Department of Medicine Geriatrics, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    QJM 97:63-74. 2004
    ..Choice of treatment will depend on the underlying causes of bone loss, efficacy in any particular situation, cost, patient preference and the potential non-skeletal advantages and disadvantages...
  8. doi request reprint The prevalence of osteoporosis in patients with severe hip and knee osteoarthritis awaiting joint arthroplasty
    Elizabeth A Lingard
    Department of Orthopaedic Surgery, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK
    Age Ageing 39:234-9. 2010
    ..the presence of osteoporosis in patients with hip and knee osteoarthritis (OA) has important implications for understanding disease progression and providing optimal surgical and medical management...
  9. ncbi request reprint Mutifactorial analysis of risk factors for reduced bone mineral density in patients with Crohn's disease
    Sarah A Bartram
    Department of Medicine, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, United Kingdom
    World J Gastroenterol 12:5680-6. 2006
    ..To determine the prevalence of osteoporosis in a cohort of patients with Crohn's disease (CD) and to identify the relative significance of risk factors for osteoporosis...
  10. ncbi request reprint Self-report overestimates true height loss: implications for diagnosis of osteoporosis
    Fraser Birrell
    Department of Rheumatology, University of Newcastle upon Tyne, 4th Floor, Cookson Building, UK
    Clin Rheumatol 24:590-2. 2005
    ..In clinical practice, objective confirmation of reported height loss should be undertaken, wherever possible, prior to further investigation...
  11. ncbi request reprint Low bone mineral density measurements in care home residents--a treatable cause of fractures
    Terry J Aspray
    Department of Geriatric Medicine, Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, UK
    Age Ageing 35:37-41. 2006
    ..to assess predictors of fracture risk and treatment for osteoporosis among elderly care home residents...
  12. ncbi request reprint Assessment of vitamin D status in male osteoporosis
    Ziad H Al-oanzi
    School of Clinical and Laboratory Sciences, The Medical School, University of Newcastle, Newcastle upon Tyne, United Kingdom
    Clin Chem 52:248-54. 2006
    ....
  13. doi request reprint Treatment of osteoporosis in women intolerant of oral bisphosphonates
    Terry J Aspray
    Musculoskeletal Unit, Freeman Hospital, Newcastle upon Tyne, UK
    Maturitas 71:76-8. 2012
    ..Finally, consideration is given to clinical risk factors, including aspects of lifestyle which may be modified to decrease fracture risk...
  14. ncbi request reprint Non-response to osteoporosis treatment
    Roger M Francis
    University of Newcastle upon Tyne, UK
    J Br Menopause Soc 10:76-80. 2004
    ..Consideration should also be given to the addition of calcium and vitamin D supplementation and the use of alternative treatments for osteoporosis...
  15. pmc Osteoporosis
    S P Tuck
    Musculoskeletal Unit, Freeman Hospital, Newcastle upon Tyne, UK
    Postgrad Med J 78:526-32. 2002
    ..It is important that treatment is tailored to the individual patient, to ensure compliance and optimise the potential benefits...
  16. ncbi request reprint Androgen replacement in aging men
    R M Francis
    Musculoskeletal Unit, Freeman Hospital, Newcastle upon Tyne, UK
    Calcif Tissue Int 69:235-8. 2001
    ..Further studies are required to confirm the safety and efficacy of testosterone replacement in hypogonadal and eugonadal men with osteoporosis...
  17. doi request reprint How the Newcastle Thousand Families birth cohort study has contributed to the understanding of the impact of birth weight and early life socioeconomic position on disease in later life
    Mark S Pearce
    Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK
    Maturitas 72:23-8. 2012
    ....
  18. ncbi request reprint Effect of intermittent cyclical disodium etidronate therapy on bone mineral density in men with vertebral fractures
    F H Anderson
    Freeman Hospital, High Heaton, Newcastle upon Tyne, UK
    Age Ageing 26:359-65. 1997
    ..to investigate the effects of oral intermittent cyclical etidronate therapy on bone mineral density (BMD) in men with idiopathic vertebral osteoporosis...
  19. doi request reprint Zic1 transcription factor in bone: neural developmental protein regulates mechanotransduction in osteocytes
    Michail Kalogeropoulos
    Musculoskeletal Research Group, ICM, The Medical School, Newcastle University, Newcastle upon Tyne, UK
    FASEB J 24:2893-903. 2010
    ..We conclude that Zic1, a neural developmental transcription factor, plays an important role in shear flow mechanotransduction in osteocytes...
  20. pmc Lifecourse study of bone health at age 49-51 years: the Newcastle thousand families cohort study
    Mark S Pearce
    School of Clinical Medical Sciences, University of Newcastle upon Tyne, Sir James Spence Institute of Child Health, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK
    J Epidemiol Community Health 59:475-80. 2005
    ....
  21. ncbi request reprint Mutational and polymorphic analysis of the estradiol receptor-alpha gene in men with symptomatic vertebral fractures
    L C Allcroft
    School of Clinical and Laboratory Sciences, The Medical School, University of Newcastle, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK
    Calcif Tissue Int 71:400-5. 2002
    ..Furthermore, polymorphic variation of the ER-alpha gene appears to have little effect on the pathogenesis of osteoporosis in men...
  22. ncbi request reprint A randomized controlled trial of calcium with vitamin D, alone or in combination with intravenous pamidronate, for the treatment of low bone mineral density associated with Crohn's disease
    S A Bartram
    Musculoskeletal Unit Department of Biochemistry, Freeman Hospital, Newcastle upon Tyne, UK
    Aliment Pharmacol Ther 18:1121-7. 2003
    ..Osteoporosis is a common complication of Crohn's disease...
  23. ncbi request reprint Vitamin D-binding protein gene microsatellite polymorphism influences BMD and risk of fractures in men
    Z H Al-oanzi
    School of Clinical and Laboratory Sciences, The Medical School, University of Newcastle, Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK
    Osteoporos Int 19:951-60. 2008
    ..We confirm the results of an earlier study in a different cohort, showing relationship between certain genotypes of (TAAAn)-Alu repeats and reduced BMD and vertebral fractures...
  24. ncbi request reprint Mitochondrial DNA deletion associated oxidative stress and severe male osteoporosis
    S S Varanasi
    Department of Clinical Biochemistry, University of Newcastle, Newcastle upon Tyne, UK
    Osteoporos Int 10:143-9. 1999
    ..727/cm(2); Z-score -2.58) and the proportion of affected mitochondria was lower (25%). The significance of these findings is discussed and the possible relation between oxidative stress and accelerated bone loss is examined...
  25. pmc Influence of IL-6, COL1A1, and VDR gene polymorphisms on bone mineral density in Crohn's disease
    C E Todhunter
    Department of Medicine, Freeman Hospital, High Heaton, Newcastle upon Tyne, NE7 7DN, UK
    Gut 54:1579-84. 2005
    ..The pathogenesis of reduced bone mineral density (BMD) is multifactorial. A range of genetic factors have been implicated in other populations of patients with osteoporosis...
  26. ncbi request reprint Differences in bone mineral density and geometry in men and women: the Newcastle Thousand Families Study at 50 years old
    S P Tuck
    Department of Rheumatology, Musculoskeletal Unit, Freeman Hospital, Freeman Road, Newcastle upon Tyne NE7 7DN, UK
    Br J Radiol 78:493-8. 2005
    ..We conclude that there are gender differences in BMD, skeletal size and geometry in middle aged men and women, which together with the subsequent rate of bone loss, may influence fracture risk in later life...
  27. ncbi request reprint The use of digital X-ray radiogrammetry and peripheral dual energy X-ray absorptiometry in patients attending fracture clinic after distal forearm fracture
    M R Reed
    Freeman Hospital, Heaton, Newcastle upon Tyne, UK
    Bone 34:716-9. 2004
    ..The potential advantage of DXR over calcaneal pDXA measurements is that standard forearm X-ray obtained as part of fracture management could be used...
  28. ncbi request reprint Randomized controlled trial of hip protectors among women living in the community
    Yvonne F Birks
    Primary Care Hip Protector Trial Group, York Trials Unit, Department of Health Sciences, York University, Area 4, Seebhom Rowntree Building, YO10 5DD, UK
    Osteoporos Int 15:701-6. 2004
    ..To assess whether hip protectors used among women living in the community in the United Kingdom and at high risk of hip fracture, lead to a reduction in hip fracture...
  29. pmc Nutrition and bone health projects funded by the UK Food Standards Agency: have they helped to inform public health policy?
    Margaret Ashwell
    Ashwell Associates Europe Ltd, Ashwell, Hertfordshire SG7 5PZ and Oxford Brookes University, Oxford OX3 0BP, UK
    Br J Nutr 99:198-205. 2008
    ..The major research gap identified was the need to investigate vitamin D status to define deficiency, insufficiency and depletion across age and ethnic groups in relation to bone health...
  30. ncbi request reprint Clodronate reduces vertebral fracture risk in women with postmenopausal or secondary osteoporosis: results of a double-blind, placebo-controlled 3-year study
    Eugene McCloskey
    Division of Genomic Medicine, The World Health Organization Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, United Kingdom
    J Bone Miner Res 19:728-36. 2004
    ..The incidence of vertebral fractures was significantly reduced by 46%. The effect was not modified by the underlying cause of osteoporosis or other baseline factors including bone mineral density, QUS, weight, and smoking...
  31. ncbi request reprint Association between vertebral fracture and increased mortality in osteoporotic patients
    Tarja Jalava
    Leiras, Helsinki, Finland
    J Bone Miner Res 18:1254-60. 2003
    ..Prevalent vertebral fractures were associated with increased mortality, but other known predictors of mortality explain a significant proportion of the excess risk...
  32. ncbi request reprint A prospective evaluation of bone mineral density measurement in females who have fallen
    Julia L Newton
    Institute for Ageing and Health, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Age Ageing 32:497-502. 2003
    ..This predicts overall fracture risk as effectively as dual X-ray at the spine and hip, although site specific measurements provide the best estimate of fracture risk at a particular location...