Maria Christina Zennaro

Summary

Country: France

Publications

  1. doi request reprint Mineralocorticoid receptors in the metabolic syndrome
    Maria Christina Zennaro
    INSERM, U970, Paris Cardiovascular Research Center PARCC, 75015 Paris, France
    Trends Endocrinol Metab 20:444-51. 2009
  2. pmc A network perspective on metabolic inconsistency
    Nikolaus Sonnenschein
    School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany
    BMC Syst Biol 6:41. 2012
  3. doi request reprint Aldosterone resistance: structural and functional considerations and new perspectives
    Maria Christina Zennaro
    INSERM U970, Paris Cardiovascular Research Center, Paris, France
    Mol Cell Endocrinol 350:206-15. 2012
  4. doi request reprint Aldosterone-producing adenoma formation in the adrenal cortex involves expression of stem/progenitor cell markers
    Sheerazed Boulkroun
    Institut National de la Santé et de la Recherche Médicale Unité 970, PARCC, 56 rue Leblanc, 75015 Paris, France
    Endocrinology 152:4753-63. 2011
  5. doi request reprint Genetics of mineralocorticoid excess: an update for clinicians
    Maria Christina Zennaro
    INSERM, UMRS_970, Paris Cardiovascular Research Center, 56 rue Leblanc, 75015 Paris, France
    Eur J Endocrinol 169:R15-25. 2013
  6. pmc Mineralocorticoid receptor mutations and a severe recessive pseudohypoaldosteronism type 1
    Edwige Ludiwyne Hubert
    INSERM, U970, Paris Cardiovascular Research Center PARCC, 56, rue Leblanc, 75015 Paris, France
    J Am Soc Nephrol 22:1997-2003. 2011
  7. doi request reprint KCNJ5 mutations in aldosterone producing adenoma and relationship with adrenal cortex remodeling
    Sheerazed Boulkroun
    Institut National de la Sante et de la Recherche Medicale INSERM, U970, Paris Cardiovascular Research Center, Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France
    Mol Cell Endocrinol 371:221-7. 2013
  8. doi request reprint Prevalence, clinical, and molecular correlates of KCNJ5 mutations in primary aldosteronism
    Sheerazed Boulkroun
    Institut National de la Sante et de la Recherche Medicale, Unité Mixte de Recherche Scientifique 970, Paris Cardiovascular Research Center, Paris, France
    Hypertension 59:592-8. 2012
  9. doi request reprint Mineralocorticoid receptor mutations differentially affect individual gene expression profiles in pseudohypoaldosteronism type 1
    Fabio L Fernandes-Rosa
    Department of Puericulture and Pediatrics, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto 14040 900, Brazil
    J Clin Endocrinol Metab 96:E519-27. 2011
  10. ncbi request reprint Different inactivating mutations of the mineralocorticoid receptor in fourteen families affected by type I pseudohypoaldosteronism
    Paola Sartorato
    Institut National de la Sante et de la Recherche Medicale, Unité 478, Faculte de Medecine Xavier Bichat, 75018 Paris, France
    J Clin Endocrinol Metab 88:2508-17. 2003

Collaborators

  • Decio Armanini
  • Pierre Francois Plouin
  • Herve Lefebvre
  • Enzo Lalli
  • Jerome Fagart
  • Bruno Feve
  • Ursula Kuhnle
  • Marcus Quinkler
  • Véronique Abadie
  • Sheerazed Boulkroun
  • Franco Veglio
  • Claudio Letizia
  • Xavier Jeunemaitre
  • Brigitte Escoubet
  • Fabio L Fernandes-Rosa
  • Edwige Ludiwyne Hubert
  • Nikolaus Sonnenschein
  • Arndt Benecke
  • Marie Edith Rafestin-Oblin
  • Marc Lombes
  • Say Viengchareun
  • Lucie Pujo
  • Paola Sartorato
  • Laurent Pascual Le Tallec
  • Laurence Mangin
  • Sylvie Chillon
  • Jean Pierre Laisy
  • Camille Couffignal
  • Cédric Laouénan
  • France Mentre
  • Jean Michel Serfaty
  • Sebastian Eilebrecht
  • Jose Felipe Golib Dzib
  • Annick Lesne
  • Marc Thorsten Hütt
  • Debora Gomes
  • Michel Fay
  • Nicolas Tchitchek
  • Chantal Metz
  • Raphaël Teissier
  • Sonir R Antonini
  • Elodie Jouanno
  • Françoise Gary
  • Dimitris T Papadimitriou
  • Aurélie Claës
  • Marie Hélène Lecornec
  • Paola Loli
  • Christiane De Gennes
  • Elodie Poisson
  • Marie Christine Lecomte
  • Yasmina Khaldi
  • Patrick Niaudet
  • Eliana di Battista
  • Anna Maria Fusco
  • Véronique Poulet-Young
  • Alain Racine
  • Remi Salomon
  • Anne Laure Lapeyraque
  • Maurizio Bosio
  • Arturo Naselli
  • Jean Pierre Chabrolle
  • Massimiliano Caprio
  • Anne Dejean
  • Olivier Kirsh
  • Laurent Pascual-Le Tallec

Detail Information

Publications16

  1. doi request reprint Mineralocorticoid receptors in the metabolic syndrome
    Maria Christina Zennaro
    INSERM, U970, Paris Cardiovascular Research Center PARCC, 75015 Paris, France
    Trends Endocrinol Metab 20:444-51. 2009
    ....
  2. pmc A network perspective on metabolic inconsistency
    Nikolaus Sonnenschein
    School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany
    BMC Syst Biol 6:41. 2012
    ..A network-driven interpretation of gene expression data has the potential of suggesting novel classifiers for pathological cellular states and of contributing to a general theoretical understanding of gene regulation...
  3. doi request reprint Aldosterone resistance: structural and functional considerations and new perspectives
    Maria Christina Zennaro
    INSERM U970, Paris Cardiovascular Research Center, Paris, France
    Mol Cell Endocrinol 350:206-15. 2012
    ..We will also discuss genotype-phenotype correlations and new clinical and genetic entities that may prove relevant for patient's care in neonates with renal salt losing syndromes and/or failure to thrive...
  4. doi request reprint Aldosterone-producing adenoma formation in the adrenal cortex involves expression of stem/progenitor cell markers
    Sheerazed Boulkroun
    Institut National de la Santé et de la Recherche Médicale Unité 970, PARCC, 56 rue Leblanc, 75015 Paris, France
    Endocrinology 152:4753-63. 2011
    ..Our data suggest that both APA and adjacent ZG present characteristics of stem/precursor cells; the reexpression of genes involved in fetal adrenal development could underlie excessive ZG cell proliferation and APA formation...
  5. doi request reprint Genetics of mineralocorticoid excess: an update for clinicians
    Maria Christina Zennaro
    INSERM, UMRS_970, Paris Cardiovascular Research Center, 56 rue Leblanc, 75015 Paris, France
    Eur J Endocrinol 169:R15-25. 2013
    ..Finally, we outline the cardiovascular, renal, and metabolic consequences of mineralocorticoid excess beyond blood pressure regulation...
  6. pmc Mineralocorticoid receptor mutations and a severe recessive pseudohypoaldosteronism type 1
    Edwige Ludiwyne Hubert
    INSERM, U970, Paris Cardiovascular Research Center PARCC, 56, rue Leblanc, 75015 Paris, France
    J Am Soc Nephrol 22:1997-2003. 2011
    ..This might prove relevant for patient's care in neonatal salt losing disorders and may affect renal salt handling and blood pressure in the general population...
  7. doi request reprint KCNJ5 mutations in aldosterone producing adenoma and relationship with adrenal cortex remodeling
    Sheerazed Boulkroun
    Institut National de la Sante et de la Recherche Medicale INSERM, U970, Paris Cardiovascular Research Center, Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France
    Mol Cell Endocrinol 371:221-7. 2013
    ..The cell composition of APA was not significantly different between groups. These results indicate that KCNJ5 mutations are not correlated with adrenal cortex remodeling in APA...
  8. doi request reprint Prevalence, clinical, and molecular correlates of KCNJ5 mutations in primary aldosteronism
    Sheerazed Boulkroun
    Institut National de la Sante et de la Recherche Medicale, Unité Mixte de Recherche Scientifique 970, Paris Cardiovascular Research Center, Paris, France
    Hypertension 59:592-8. 2012
    ..KCNJ5 mutation carriers are more likely to be females; younger age and higher aldosterone levels at diagnosis suggest that KCNJ5 mutations may be associated with a more florid phenotype of primary aldosteronism...
  9. doi request reprint Mineralocorticoid receptor mutations differentially affect individual gene expression profiles in pseudohypoaldosteronism type 1
    Fabio L Fernandes-Rosa
    Department of Puericulture and Pediatrics, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto 14040 900, Brazil
    J Clin Endocrinol Metab 96:E519-27. 2011
    ..Type 1 pseudohypoaldosteronism (PHA1), a primary form of mineralocorticoid resistance, is due to inactivating mutations of the NR3C2 gene, coding for the mineralocorticoid receptor (MR)...
  10. ncbi request reprint Different inactivating mutations of the mineralocorticoid receptor in fourteen families affected by type I pseudohypoaldosteronism
    Paola Sartorato
    Institut National de la Sante et de la Recherche Medicale, Unité 478, Faculte de Medecine Xavier Bichat, 75018 Paris, France
    J Clin Endocrinol Metab 88:2508-17. 2003
    ..Their absence in some families underscores the importance of an extensive investigation of the hMR gene and the role of precise diagnostic procedures to allow for identification of other genes potentially involved in the disease...
  11. ncbi request reprint Protein inhibitor of activated signal transducer and activator of transcription 1 interacts with the N-terminal domain of mineralocorticoid receptor and represses its transcriptional activity: implication of small ubiquitin-related modifier 1 modification
    Laurent Pascual Le Tallec
    Institut National de la Sante et de la Recherche Medicale, U478, Faculte de Medecine Xavier Bichat, 16 rue Henri Huchard, 75870 Paris Cedex 18, France
    Mol Endocrinol 17:2529-42. 2003
    ..Taken together, our results identify a novel function for PIAS1 which interacts with the N-terminal domain of hMR and represses its ligand-dependent transcriptional activity, at least in part, through SUMO modifications...
  12. doi request reprint Cardiovascular effects of aldosterone: insight from adult carriers of mineralocorticoid receptor mutations
    Brigitte Escoubet
    Assistance Publique Hopitaux de Paris, Hopital Bichat Claude Bernard, Paris, France
    Circ Cardiovasc Genet 6:381-90. 2013
    ..This suggests that the cardiovascular consequences of aldosterone excess require full mineralocorticoid receptor signaling. Clinical Trial Registration- http://www.clinicaltrials.gov; unique identifier: NCT00646828. ..
  13. ncbi request reprint Mineralocorticoid receptor mutations are the principal cause of renal type 1 pseudohypoaldosteronism
    Lucie Pujo
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Department of Genetics, Paris, France
    Hum Mutat 28:33-40. 2007
    ..The other patients without MR mutations might have different diseases resembling to PHA1 in the neonatal period, which could be identified by extensive clinical and functional exploration...
  14. doi request reprint Adrenal cortex remodeling and functional zona glomerulosa hyperplasia in primary aldosteronism
    Sheerazed Boulkroun
    INSERM U970, Paris Cardiovascular Research Center, Paris, France
    Hypertension 56:885-92. 2010
    ..Transcriptional phenotyping is not in favor of this being an intermediate step toward the formation of aldosterone-producing adenoma...
  15. ncbi request reprint Brown adipocytes are novel sites of expression and regulation of adiponectin and resistin
    Say Viengchareun
    INSERM U478, Institut Fédératif de Recherche Claude Bernard, Faculte de Medecine Xavier Bichat, 16 rue Henri Huchard, 75018, Paris, France
    FEBS Lett 532:345-50. 2002
    ....
  16. ncbi request reprint Mineralocorticoid resistance
    Maria Christina Zennaro
    Institut National de la Sante et de la Recherche Medicale, Unité 478, Faculte de Medecine, Xavier Bichat, B P 416, 16 rue H Huchard, 75870 Paris 18, France
    Trends Endocrinol Metab 15:264-70. 2004
    ..Precise clinical diagnosis and establishment of intermediate phenotypes should be helpful for identifying other genes involved in PHA1 and gaining new insight into the regulation of sodium homeostasis...