Michel Werner

Summary

Country: France

Publications

  1. doi request reprint Structure-function analysis of RNA polymerases I and III
    Michel Werner
    CEA, IRCM, F 91057 Evry Cedex, France
    Curr Opin Struct Biol 19:740-5. 2009
  2. doi request reprint Mediator-dependent recruitment of TFIIH modules in preinitiation complex
    Cyril Esnault
    CEA, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Mol Cell 31:337-46. 2008
  3. pmc Genome-wide location analysis reveals a role of TFIIS in RNA polymerase III transcription
    Yad Ghavi-Helm
    CEA, iBiTec S, Gif sur Yvette Cedex F 91191, France
    Genes Dev 22:1934-47. 2008
  4. doi request reprint Direct interaction of RNA polymerase II and mediator required for transcription in vivo
    Julie Soutourina
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, Service de Biologie Intégrative et Génétique Moléculaire, Gif sur Yvette Cedex, France
    Science 331:1451-4. 2011
  5. pmc Two RNA polymerase I subunits control the binding and release of Rrn3 during transcription
    Frederic Beckouët
    CEA, iBiTec S, Service de Biologie Intégrative and Génétique Moléculaire, Gif sur Yvette Cedex F 91191, France
    Mol Cell Biol 28:1596-605. 2008
  6. pmc Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells
    Lucie Carrière
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Nucleic Acids Res 40:270-83. 2012

Collaborators

  • Julie Soutourina
  • Yad Ghavi-Helm
  • Lucie Carrière
  • Jean Christophe Aude
  • Pierre Thuriaux
  • Frederic Beckouët
  • Cyril Esnault
  • Celine Keime
  • Sébastien Graziani
  • Ivo Gut
  • Sylvie Jounier
  • Mario Foglio
  • Janos Murvai
  • Fayçal Boussouar
  • Olivier Alibert
  • Matthieu Gerard
  • Hélène Humbertclaude
  • Marta Gut
  • Mark Lathrop
  • Sylvie Labarre-Mariotte
  • Frank Holstege
  • Yasuhisa Nogi
  • Olivier Gadal
  • Magali Michaut
  • Yukiko Imazawa
  • Benjamin Albert
  • Sylvain Brun
  • Claire Boschiero
  • Joel Acker
  • Nynke Van Berkum

Detail Information

Publications6

  1. doi request reprint Structure-function analysis of RNA polymerases I and III
    Michel Werner
    CEA, IRCM, F 91057 Evry Cedex, France
    Curr Opin Struct Biol 19:740-5. 2009
    ..Unexpectedly, even though Pol I and III, but not Pol II, have an intrinsic RNA cleavage activity, it was found that TFIIS Pol II cleavage stimulation factor also played a general role in Pol III transcription...
  2. doi request reprint Mediator-dependent recruitment of TFIIH modules in preinitiation complex
    Cyril Esnault
    CEA, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Mol Cell 31:337-46. 2008
    ..We conclude that the Mediator head module plays a critical role in TFIIH and TFIIE recruitment to the PIC. We identify steps in PIC formation that suggest a branched assembly pathway...
  3. pmc Genome-wide location analysis reveals a role of TFIIS in RNA polymerase III transcription
    Yad Ghavi-Helm
    CEA, iBiTec S, Gif sur Yvette Cedex F 91191, France
    Genes Dev 22:1934-47. 2008
    ..In vitro transcription assays suggested that TFIIS may affect Pol III start site selection. These data provide strong in vivo and in vitro evidence in favor of a role of TFIIS as a general Pol III transcription factor...
  4. doi request reprint Direct interaction of RNA polymerase II and mediator required for transcription in vivo
    Julie Soutourina
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, Service de Biologie Intégrative et Génétique Moléculaire, Gif sur Yvette Cedex, France
    Science 331:1451-4. 2011
    ..Our findings suggest that a direct interaction between Mediator and Pol II is generally required for transcription of class II genes in eukaryotes...
  5. pmc Two RNA polymerase I subunits control the binding and release of Rrn3 during transcription
    Frederic Beckouët
    CEA, iBiTec S, Service de Biologie Intégrative and Génétique Moléculaire, Gif sur Yvette Cedex F 91191, France
    Mol Cell Biol 28:1596-605. 2008
    ..These data suggest a dual role of the Rpa49-Rpa34 dimer during the recruitment of Rrn3 and its subsequent dissociation from the elongating polymerase...
  6. pmc Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells
    Lucie Carrière
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Nucleic Acids Res 40:270-83. 2012
    ..We found that, as in Saccharomyces cerevisiae, TFIIS is associated with class III genes and also with SINEs suggesting that TFIIS is a Pol III transcription factor in mammals...