Michel Werner

Summary

Country: France

Publications

  1. doi request reprint Structure-function analysis of RNA polymerases I and III
    Michel Werner
    CEA, IRCM, F 91057 Evry Cedex, France
    Curr Opin Struct Biol 19:740-5. 2009
  2. pmc Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells
    Lucie Carrière
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Nucleic Acids Res 40:270-83. 2012
  3. pmc Genome-wide location analysis reveals a role of TFIIS in RNA polymerase III transcription
    Yad Ghavi-Helm
    CEA, iBiTec S, Gif sur Yvette Cedex F 91191, France
    Genes Dev 22:1934-47. 2008
  4. doi request reprint Mediator-dependent recruitment of TFIIH modules in preinitiation complex
    Cyril Esnault
    CEA, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Mol Cell 31:337-46. 2008
  5. pmc Two RNA polymerase I subunits control the binding and release of Rrn3 during transcription
    Frederic Beckouët
    CEA, iBiTec S, Service de Biologie Intégrative and Génétique Moléculaire, Gif sur Yvette Cedex F 91191, France
    Mol Cell Biol 28:1596-605. 2008
  6. pmc Mediator links transcription and DNA repair by facilitating Rad2/XPG recruitment
    Fanny Eyboulet
    FRE3377, Institut de Biologie et de Technologies de Saclay iBiTec S, Commissariat à l Energie Atomique et aux Energies Alternatives CEA, F 91191 Gif sur Yvette Cedex, France
    Genes Dev 27:2549-62. 2013
  7. pmc Rsc4 connects the chromatin remodeler RSC to RNA polymerases
    Julie Soutourina
    Service de Biochimie et Génétique Moléculaire, Bâtiment 144, CEA Saclay, F 91191 Gif sur Yvette Cedex, France
    Mol Cell Biol 26:4920-33. 2006
  8. doi request reprint Direct interaction of RNA polymerase II and mediator required for transcription in vivo
    Julie Soutourina
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, Service de Biologie Intégrative et Génétique Moléculaire, Gif sur Yvette Cedex, France
    Science 331:1451-4. 2011
  9. pmc An Rpb4/Rpb7-like complex in yeast RNA polymerase III contains the orthologue of mammalian CGRP-RCP
    Magali Siaut
    Service de Biochimie et de Génétique Moléculaire, CEA Saclay, F 91191 Gif sur Yvette Cedex, France
    Mol Cell Biol 23:195-205. 2003
  10. ncbi request reprint The yeast homolog of human PinX1 is involved in rRNA and small nucleolar RNA maturation, not in telomere elongation inhibition
    Benjamin Guglielmi
    Service de Biochimie et Génétique Moléculaire, Bâtiment 144, Commissariat à l Energie Atomique Saclay, F 91191 Gif sur Yvette Cedex, France
    J Biol Chem 277:35712-9. 2002

Collaborators

  • Julie Soutourina
  • Andre Sentenac
  • Isabelle Callebaut
  • Christine Conesa
  • Pierre Thuriaux
  • Yad Ghavi-Helm
  • Jean Christophe Aude
  • Fanny Eyboulet
  • Olivier Alibert
  • Lucie Carrière
  • Frederic Beckouët
  • Cyril Esnault
  • Magali Siaut
  • Benjamin Guglielmi
  • Mirène Fauchon
  • Helen Neil
  • Thomas Eychenne
  • Camille Cibot
  • Celine Keime
  • Sylvie Jounier
  • Mario Foglio
  • Janos Murvai
  • Ivo Gut
  • Matthieu Gerard
  • Marta Gut
  • Fayçal Boussouar
  • Sébastien Graziani
  • Hélène Humbertclaude
  • Mark Lathrop
  • Claire Boschiero
  • Magali Michaut
  • Yukiko Imazawa
  • Sylvie Labarre-Mariotte
  • Frank Holstege
  • Yasuhisa Nogi
  • Olivier Gadal
  • Benjamin Albert
  • Sylvain Brun
  • Joel Acker
  • Nynke Van Berkum
  • Maria Laura Ferri
  • Emilie Levivier
  • Cécile Zaros
  • Magali Court
  • Cyrille Petat
  • Gilles Lagniel
  • Gérard Marguerie
  • Pascal Soularue
  • Luis Lombardia
  • Jean Labarre

Detail Information

Publications11

  1. doi request reprint Structure-function analysis of RNA polymerases I and III
    Michel Werner
    CEA, IRCM, F 91057 Evry Cedex, France
    Curr Opin Struct Biol 19:740-5. 2009
    ..Unexpectedly, even though Pol I and III, but not Pol II, have an intrinsic RNA cleavage activity, it was found that TFIIS Pol II cleavage stimulation factor also played a general role in Pol III transcription...
  2. pmc Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells
    Lucie Carrière
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Nucleic Acids Res 40:270-83. 2012
    ..We found that, as in Saccharomyces cerevisiae, TFIIS is associated with class III genes and also with SINEs suggesting that TFIIS is a Pol III transcription factor in mammals...
  3. pmc Genome-wide location analysis reveals a role of TFIIS in RNA polymerase III transcription
    Yad Ghavi-Helm
    CEA, iBiTec S, Gif sur Yvette Cedex F 91191, France
    Genes Dev 22:1934-47. 2008
    ..In vitro transcription assays suggested that TFIIS may affect Pol III start site selection. These data provide strong in vivo and in vitro evidence in favor of a role of TFIIS as a general Pol III transcription factor...
  4. doi request reprint Mediator-dependent recruitment of TFIIH modules in preinitiation complex
    Cyril Esnault
    CEA, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Mol Cell 31:337-46. 2008
    ..We conclude that the Mediator head module plays a critical role in TFIIH and TFIIE recruitment to the PIC. We identify steps in PIC formation that suggest a branched assembly pathway...
  5. pmc Two RNA polymerase I subunits control the binding and release of Rrn3 during transcription
    Frederic Beckouët
    CEA, iBiTec S, Service de Biologie Intégrative and Génétique Moléculaire, Gif sur Yvette Cedex F 91191, France
    Mol Cell Biol 28:1596-605. 2008
    ..These data suggest a dual role of the Rpa49-Rpa34 dimer during the recruitment of Rrn3 and its subsequent dissociation from the elongating polymerase...
  6. pmc Mediator links transcription and DNA repair by facilitating Rad2/XPG recruitment
    Fanny Eyboulet
    FRE3377, Institut de Biologie et de Technologies de Saclay iBiTec S, Commissariat à l Energie Atomique et aux Energies Alternatives CEA, F 91191 Gif sur Yvette Cedex, France
    Genes Dev 27:2549-62. 2013
    ..Our results suggest that Mediator is involved in DNA repair by facilitating Rad2 recruitment to transcribed genes...
  7. pmc Rsc4 connects the chromatin remodeler RSC to RNA polymerases
    Julie Soutourina
    Service de Biochimie et Génétique Moléculaire, Bâtiment 144, CEA Saclay, F 91191 Gif sur Yvette Cedex, France
    Mol Cell Biol 26:4920-33. 2006
    ....
  8. doi request reprint Direct interaction of RNA polymerase II and mediator required for transcription in vivo
    Julie Soutourina
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, Service de Biologie Intégrative et Génétique Moléculaire, Gif sur Yvette Cedex, France
    Science 331:1451-4. 2011
    ..Our findings suggest that a direct interaction between Mediator and Pol II is generally required for transcription of class II genes in eukaryotes...
  9. pmc An Rpb4/Rpb7-like complex in yeast RNA polymerase III contains the orthologue of mammalian CGRP-RCP
    Magali Siaut
    Service de Biochimie et de Génétique Moléculaire, CEA Saclay, F 91191 Gif sur Yvette Cedex, France
    Mol Cell Biol 23:195-205. 2003
    ..These RNA polymerase subunits appear to have evolved to meet the distinct requirements of the multiple forms of RNA polymerases...
  10. ncbi request reprint The yeast homolog of human PinX1 is involved in rRNA and small nucleolar RNA maturation, not in telomere elongation inhibition
    Benjamin Guglielmi
    Service de Biochimie et Génétique Moléculaire, Bâtiment 144, Commissariat à l Energie Atomique Saclay, F 91191 Gif sur Yvette Cedex, France
    J Biol Chem 277:35712-9. 2002
    ..Conversely, we found that Gno1p does not exhibit the in vivo telomerase inhibitor activity of PinX1...
  11. ncbi request reprint Sulfur sparing in the yeast proteome in response to sulfur demand
    Mirène Fauchon
    Service de Biochimie et Génétique Moléculaire, Batiment 142, CEA Saclay, F 91191 Gif sur Yvette Cedex, France
    Mol Cell 9:713-23. 2002
    ..This proteomic adaptation is essentially regulated at the mRNA level. The main transcriptional activator of the sulfate assimilation pathway, Met4p, plays an essential role in this sulfur-sparing response...