Michel Werner

Summary

Country: France

Publications

  1. ncbi Structure-function analysis of RNA polymerases I and III
    Michel Werner
    CEA, IRCM, F 91057 Evry Cedex, France
    Curr Opin Struct Biol 19:740-5. 2009
  2. ncbi Mediator-dependent recruitment of TFIIH modules in preinitiation complex
    Cyril Esnault
    CEA, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Mol Cell 31:337-46. 2008
  3. ncbi Genome-wide location analysis reveals a role of TFIIS in RNA polymerase III transcription
    Yad Ghavi-Helm
    CEA, iBiTec S, Gif sur Yvette Cedex F 91191, France
    Genes Dev 22:1934-47. 2008
  4. ncbi Direct interaction of RNA polymerase II and mediator required for transcription in vivo
    Julie Soutourina
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, Service de Biologie Intégrative et Génétique Moléculaire, Gif sur Yvette Cedex, France
    Science 331:1451-4. 2011
  5. ncbi Two RNA polymerase I subunits control the binding and release of Rrn3 during transcription
    Frederic Beckouët
    CEA, iBiTec S, Service de Biologie Intégrative and Génétique Moléculaire, Gif sur Yvette Cedex F 91191, France
    Mol Cell Biol 28:1596-605. 2008
  6. ncbi Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells
    Lucie Carrière
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Nucleic Acids Res 40:270-83. 2012

Collaborators

  • Julie Soutourina
  • Yad Ghavi-Helm
  • Lucie Carrière
  • Jean Christophe Aude
  • Frederic Beckouët
  • Cyril Esnault
  • Pierre Thuriaux
  • Marta Gut
  • Mario Foglio
  • Janos Murvai
  • Matthieu Gerard
  • Hélène Humbertclaude
  • Celine Keime
  • Sébastien Graziani
  • Sylvie Jounier
  • Olivier Alibert
  • Ivo Gut
  • Fayçal Boussouar
  • Mark Lathrop
  • Jean-Christophe Aude
  • Claire Boschiero
  • Frank Holstege
  • Benjamin Albert
  • Magali Michaut
  • Yukiko Imazawa
  • Sylvie Labarre-Mariotte
  • Olivier Gadal
  • Sylvain Brun
  • Joel Acker
  • Yasuhisa Nogi
  • Nynke Van Berkum

Detail Information

Publications6

  1. ncbi Structure-function analysis of RNA polymerases I and III
    Michel Werner
    CEA, IRCM, F 91057 Evry Cedex, France
    Curr Opin Struct Biol 19:740-5. 2009
    ..Unexpectedly, even though Pol I and III, but not Pol II, have an intrinsic RNA cleavage activity, it was found that TFIIS Pol II cleavage stimulation factor also played a general role in Pol III transcription...
  2. ncbi Mediator-dependent recruitment of TFIIH modules in preinitiation complex
    Cyril Esnault
    CEA, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Mol Cell 31:337-46. 2008
    ..We conclude that the Mediator head module plays a critical role in TFIIH and TFIIE recruitment to the PIC. We identify steps in PIC formation that suggest a branched assembly pathway...
  3. ncbi Genome-wide location analysis reveals a role of TFIIS in RNA polymerase III transcription
    Yad Ghavi-Helm
    CEA, iBiTec S, Gif sur Yvette Cedex F 91191, France
    Genes Dev 22:1934-47. 2008
    ..In vitro transcription assays suggested that TFIIS may affect Pol III start site selection. These data provide strong in vivo and in vitro evidence in favor of a role of TFIIS as a general Pol III transcription factor...
  4. ncbi Direct interaction of RNA polymerase II and mediator required for transcription in vivo
    Julie Soutourina
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, Service de Biologie Intégrative et Génétique Moléculaire, Gif sur Yvette Cedex, France
    Science 331:1451-4. 2011
    ..Our findings suggest that a direct interaction between Mediator and Pol II is generally required for transcription of class II genes in eukaryotes...
  5. ncbi Two RNA polymerase I subunits control the binding and release of Rrn3 during transcription
    Frederic Beckouët
    CEA, iBiTec S, Service de Biologie Intégrative and Génétique Moléculaire, Gif sur Yvette Cedex F 91191, France
    Mol Cell Biol 28:1596-605. 2008
    ..These data suggest a dual role of the Rpa49-Rpa34 dimer during the recruitment of Rrn3 and its subsequent dissociation from the elongating polymerase...
  6. ncbi Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells
    Lucie Carrière
    Commissariat à l Énergie Atomique et aux Énergies Alternatives, iBiTec S, F 91191 Gif sur Yvette Cedex, France
    Nucleic Acids Res 40:270-83. 2012
    ..We found that, as in Saccharomyces cerevisiae, TFIIS is associated with class III genes and also with SINEs suggesting that TFIIS is a Pol III transcription factor in mammals...