E Weitzenblum

Summary

Country: France

Publications

  1. ncbi request reprint Pulmonary hypertension in chronic obstructive pulmonary disease
    Emmanuel Weitzenblum
    Pneumonol Alergol Pol 81:390-8. 2013
  2. ncbi request reprint Sleep and chronic obstructive pulmonary disease
    Emmanuel Weitzenblum
    Service de Pneumologie, Hopital de Hautepierre, Hopitaux Universitaires de Strasbourg, 67098 Strasbourg, France
    Sleep Med Rev 8:281-94. 2004
  3. pmc Chronic cor pulmonale
    Emmanuel Weitzenblum
    Service de Pneumologie, Hopital de Hautepierre, 67098 Strasbourg Cedex, France
    Heart 89:225-30. 2003
  4. ncbi request reprint Obstructive sleep apnea syndrome and the pulmonary circulation
    Emmanuel Weitzenblum
    Division of Pneumology, Hopital de Hautepierre, Strasbourg, France
    Ital Heart J 6:795-8. 2005
  5. ncbi request reprint [Obesity-hypoventilation syndrome]
    E Weitzenblum
    Service de Pneumologie, Hopitaux Universitaires de Strasbourg
    Rev Mal Respir 23:7S65-7S67. 2006
  6. ncbi request reprint [Sleep apnea syndrome: background; epidemiology]
    E Weitzenblum
    Service de Pneumologie, Hopital de Hautepierre, Strasbourg
    Rev Mal Respir 21:S7-12. 2004
  7. doi request reprint Overlap syndrome: obstructive sleep apnea in patients with chronic obstructive pulmonary disease
    Emmanuel Weitzenblum
    Departement de Pneumologie, Hopitaux Universitaries de Strasbourg, France
    Proc Am Thorac Soc 5:237-41. 2008
  8. ncbi request reprint [Obesity-hypoventilation syndrome]
    E Weitzenblum
    Service de Pneumologie, Pôle de Pathologie Thoracique, Hopital de Hautepierre, CHU de Strasbourg, France
    Rev Mal Respir 25:391-403. 2008
  9. doi request reprint [Pulmonary function tests in chronic obstructive pulmonary disease]
    Emmanuel Weitzenblum
    Service de Pneumologie, Nouvel Hopital Civil, Hopitaux Universitaires de Strasbourg, Strasbourg Cedex, France
    Presse Med 38:421-31. 2009
  10. doi request reprint Pulmonary hypertension in chronic obstructive pulmonary disease and interstitial lung diseases
    Emmanuel Weitzenblum
    Department of Pulmonology, Nouvel Hopital Civil, 67091 Strasbourg, France
    Semin Respir Crit Care Med 30:458-70. 2009

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Pulmonary hypertension in chronic obstructive pulmonary disease
    Emmanuel Weitzenblum
    Pneumonol Alergol Pol 81:390-8. 2013
    ..Patients with severe PH should be referred to a specialist PH centre where the possibility of inclusion in a controlled clinical trial should be considered...
  2. ncbi request reprint Sleep and chronic obstructive pulmonary disease
    Emmanuel Weitzenblum
    Service de Pneumologie, Hopital de Hautepierre, Hopitaux Universitaires de Strasbourg, 67098 Strasbourg, France
    Sleep Med Rev 8:281-94. 2004
    ..At present data are not sufficient for justifying the use of isolated nocturnal oxygen therapy in COPD patients with nocturnal desaturation but with mild daytime hypoxaemia (PaO2 > 60 mmHg)...
  3. pmc Chronic cor pulmonale
    Emmanuel Weitzenblum
    Service de Pneumologie, Hopital de Hautepierre, 67098 Strasbourg Cedex, France
    Heart 89:225-30. 2003
  4. ncbi request reprint Obstructive sleep apnea syndrome and the pulmonary circulation
    Emmanuel Weitzenblum
    Division of Pneumology, Hopital de Hautepierre, Strasbourg, France
    Ital Heart J 6:795-8. 2005
    ....
  5. ncbi request reprint [Obesity-hypoventilation syndrome]
    E Weitzenblum
    Service de Pneumologie, Hopitaux Universitaires de Strasbourg
    Rev Mal Respir 23:7S65-7S67. 2006
  6. ncbi request reprint [Sleep apnea syndrome: background; epidemiology]
    E Weitzenblum
    Service de Pneumologie, Hopital de Hautepierre, Strasbourg
    Rev Mal Respir 21:S7-12. 2004
  7. doi request reprint Overlap syndrome: obstructive sleep apnea in patients with chronic obstructive pulmonary disease
    Emmanuel Weitzenblum
    Departement de Pneumologie, Hopitaux Universitaries de Strasbourg, France
    Proc Am Thorac Soc 5:237-41. 2008
    ..Patients who are markedly hypoxemic during daytime (Pa(O(2)) < 55-60 mm Hg) should be given conventional long-term O(2) therapy in addition to nocturnal ventilation...
  8. ncbi request reprint [Obesity-hypoventilation syndrome]
    E Weitzenblum
    Service de Pneumologie, Pôle de Pathologie Thoracique, Hopital de Hautepierre, CHU de Strasbourg, France
    Rev Mal Respir 25:391-403. 2008
    ..It is defined as chronic alveolar hypoventilation (PaO2<70 mmHg, PaCO2 > or =45 mmHg) in obese patients (body mass index>30 kg/m2) who have no other respiratory disease explaining the hypoxemia-hypercapnia...
  9. doi request reprint [Pulmonary function tests in chronic obstructive pulmonary disease]
    Emmanuel Weitzenblum
    Service de Pneumologie, Nouvel Hopital Civil, Hopitaux Universitaires de Strasbourg, Strasbourg Cedex, France
    Presse Med 38:421-31. 2009
    ..Measurement of CO transfer capacity is recommended in the presence of emphysema; cardiopulmonary exercise testing (bicycle) is recommended before initiating exercise training...
  10. doi request reprint Pulmonary hypertension in chronic obstructive pulmonary disease and interstitial lung diseases
    Emmanuel Weitzenblum
    Department of Pulmonology, Nouvel Hopital Civil, 67091 Strasbourg, France
    Semin Respir Crit Care Med 30:458-70. 2009
    ..quot;New" vasodilator drugs have rarely been used in COPD and ILD patients exhibiting severe PH. In advanced ILD the presence of PH is a supplemental argument for considering lung transplantation...
  11. doi request reprint Cor pulmonale
    E Weitzenblum
    University Hospital, Strasbourg, France
    Chron Respir Dis 6:177-85. 2009
    ..Vasodilators (prostacyclin, endothelin receptor antagonists, sildenafil, nitric oxide) could be considered in patients with severe PH but controlled studies in this field are presently lacking...
  12. doi request reprint [The Overlap Syndrome: association of COPD and Obstructive Sleep Apnoea]
    E Weitzenblum
    Service de Pneumologie, Nouvel Hopital Civil, CHU de Strasbourg, 1, Place de l Hopital, 67091 Strasbourg Cedex, France
    Rev Mal Respir 27:329-40. 2010
    ..Patients who are markedly hypoxaemic during the daytime (PaO(2)<55-60 mmHg) should be given conventional long-term O(2) therapy in addition to nocturnal ventilation...
  13. ncbi request reprint [Physiological functional tests to evaluate pulmonary arterial hypertension]
    A Chaouat
    Departement de Pneumologie, Hopital de Hautepierre, Strasbourg, France
    Rev Mal Respir 22:991-7. 2005
    ..Pulmonary arterial hypertension (PAH) is a rare and complex disease, which requires careful diagnostic evaluation...
  14. ncbi request reprint The obesity-hypoventilation syndrome revisited: a prospective study of 34 consecutive cases
    R Kessler
    Department of Pulmonology and Sleep Laboratory, University Hospital, Strasbourg, France
    Chest 120:369-76. 2001
    ..We compare also OHS patients with a group of patients with the association of OSAS and COPD, also known as "overlap" patients...
  15. ncbi request reprint Outcome of COPD patients with mild daytime hypoxaemia with or without sleep-related oxygen desaturation
    A Chaouat
    Dept of Pneumology, University Hospital, Strasbourg, France
    Eur Respir J 17:848-55. 2001
    ..Such isolated nocturnal hypoxaemia or sleep-related worsening of moderate daytime hypoxaemia does not appear to favour the development of pulmonary hypertension, nor to lead to worsening of daytime blood gases...
  16. ncbi request reprint [Pulmonary hypertension associated with disorders of the respiratory system]
    A Chaouat
    Service de Pneumologie, Hopitaux Universitaires de Strasbourg
    Presse Med 34:1465-74. 2005
    ..Oxygen therapy (at least 16 h/day) is currently the best treatment for this type of pulmonary arterial hypertension...
  17. ncbi request reprint Drug therapy of sleep-related hypoxaemia
    E Weitzenblum
    University Hospital, Strasbourg, France
    Lung 168:948-54. 1990
    ..It must be emphasized that almitrine is ineffective in about 25% of COPD patients ("nonresponders") and that almitrine can be used with conventional O2 therapy in patients with severe hypoxemia (daytime PaO2 less than 55 mmHg)...
  18. ncbi request reprint Chronic obstructive pulmonary disease and sleep apnea syndrome
    E Weitzenblum
    Department of Pulmonology, , France
    Sleep 15:S33-5. 1992
    ..We conclude that the risk of developing respiratory insufficiency and cor pulmonale is higher in overlap patients...
  19. ncbi request reprint [Alveolar hypoventilation in the obese: the obesity-hypoventilation syndrome]
    E Weitzenblum
    Service de Pneumologie, Hopital de Hautepierre, 67098 Strasbourg Cedex, France
    Rev Pneumol Clin 58:83-90. 2002
    ..It should be recalled that the term Pickwickian syndrome designates obesity-hypoventilation syndrome (with or without obstructive apnea) and not obstructive sleep apnea syndrome...
  20. ncbi request reprint One year treatment with almitrine improves hypoxaemia but does not increase pulmonary artery pressure in COPD patients
    E Weitzenblum
    Hopital Universitaire, Strasbourg, France
    Eur Respir J 4:1215-22. 1991
    ..Pulmonary artery mean pressure (PAP) was stable in both groups: from 26.8 +/- 2.1 to 25.4 +/- 1.9 mmHg in group A, and from 20.6 +/- 1.1 to 20.9 +/- 1.5 mmHg in group P.(ABSTRACT TRUNCATED AT 250 WORDS)..
  21. ncbi request reprint "Natural history" of pulmonary hypertension in a series of 131 patients with chronic obstructive lung disease
    R Kessler
    Service de Pneumologie, , , 67 200 Strasbourg, France
    Am J Respir Crit Care Med 164:219-24. 2001
    ..However, in individual cases, the models of linear or logistic regression do not allow a pertinent prediction of the level of Ppa or the presence of PH at the second right heart catheterization...
  22. ncbi request reprint [Long-term oxygen therapy for chronic respiratory failure. Rationale, indications, modalities]
    E Weitzenblum
    Service de Pneumologie, hôpital universitaire de Strasbourg, 67098 Strasbourg Cedex, France
    Rev Pneumol Clin 58:195-212. 2002
    ..Patient compliance is however often insufficient. In addition to education, the best way to improve patient participation is to strive for improved quality of life with oxygen therapy (portable device, liquid oxygen) in these patients...
  23. ncbi request reprint [COPD: from early symptoms to chronic respiratory failure]
    Romain Kessler
    Hopitaux Universitaires de Strasbourg, 67098 Strasbourg 2
    Rev Prat 54:1414-8. 2004
    ..Each smoker has to be considered as potentially having COPD. Lung function measurements are required in these patients...
  24. ncbi request reprint Correlation between high-resolution computed tomography findings and lung function in pulmonary Langerhans cell histiocytosis
    Matthieu Canuet
    Department of Pneumology, University Hospital, Strasbourg, France
    Respiration 74:640-6. 2007
    ..The correlation between high-resolution computed tomography (HRCT) findings and lung function have not been studied in depth...
  25. ncbi request reprint Plasma DNA microsatellite panel as sensitive and tumor-specific marker in lung cancer patients
    Michèle Beau-Faller
    Laboratoire de Biochimie et de Biologie Moĺculaire, Hopital de Hautepierre, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Int J Cancer 105:361-70. 2003
    ..Analysis of plasma DNA using this targeted panel could be a valuable noninvasive test and a useful tool to monitor disease progression without assessing the tumor...
  26. ncbi request reprint Renal hyporesponsiveness to brain natriuretic peptide: both generation and renal activity of cGMP are decreased in patients with pulmonary hypertension
    Anne Charloux
    Institut de Physiologie, Service de Physiologie et d Explorations Fonctionnelles et EA 3072, 4 rue Kirschleger, 67085 Strasbourg Cedex, France
    Peptides 27:2993-9. 2006
    ..Therefore, PH patients hyporesponsiveness to cardiac natriuretic peptides is likely located both upstream and downstream cGMP generation. Natriuretic peptide signalling pathway disruptions might be accessible to therapy...
  27. ncbi request reprint Severe pulmonary hypertension and chronic obstructive pulmonary disease
    Ari Chaouat
    Service de Pneumologie, Hopital de Hautepierre, Avenue Moliere, 67098 Strasbourg Cedex, France
    Am J Respir Crit Care Med 172:189-94. 2005
    ..Severe pulmonary hypertension occurs occasionally in patients with chronic obstructive pulmonary disease (COPD), but no detailed description of these patients is available...
  28. ncbi request reprint Reduced pulsatility does not explain renal hyporesponsiveness to cardiac natriuretic peptides in pulmonary hypertension
    Anne Charloux
    Laboratoire des Regulations Physiologiques et des Rythmes Biologiques chez l Homme, Institut de Physiologie, 4 rue Kirschleger, 67085 Strasbourg Cedex, France
    Peptides 27:864-70. 2006
    ..In PH patients, the decrease in ANP-BNP renal efficiency is not attributable to a loss of the rhythmic pulsatility of these hormones...
  29. ncbi request reprint Evaluation of unattended automated titration to determine therapeutic continuous positive airway pressure in patients with obstructive sleep apnea
    Romain Kessler
    Service de Pneumologie, Hopital de Hautepierre, Hopitaux Universitaires de Strasbourg, France
    Chest 123:704-10. 2003
    ..The aims of the present study were to compare two different devices for automated titration and to verify if unattended automated titration is a feasible strategy to determine the therapeutic CPAP...
  30. ncbi request reprint [Therapeutic management of primary pulmonary hypertension]
    A Chaouat
    Service de Pneumologie, Hopital de Hautepierre, 1 Avenue Moliere, F67098 Strasbourg
    Presse Med 31:320-8. 2002
    ..If epoprostenol fails or provokes severe side effects, pulmonary or cardio-pulmonary transplantation should be envisaged...
  31. ncbi request reprint Procoagulant membrane microparticles correlate with the severity of pulmonary arterial hypertension
    Babe Bakouboula
    Hopitaux Universitaires de Strasbourg, Fédération de cardiologie, Strasbourg, France
    Am J Respir Crit Care Med 177:536-43. 2008
    ..Procoagulant microparticles constitute valuable hallmarks of cell damage. Microparticles also behave as cellular effectors...
  32. ncbi request reprint Allelic imbalance at loci containing FGFR, FGF, c-Met and HGF candidate genes in non-small cell lung cancer sub-types, implication for progression
    M Beau-Faller
    Laboratoire de Biochimie et de Biologie Moleculaire, Hopital de Hautepierre, Hopitaux Universitaires de Strasbourg, 67000 Strasbourg, France
    Eur J Cancer 39:2538-47. 2003
    ..Finally, alterations at loci containing FGFR and HGF candidate genes were inversely correlated to the lymph node status in SQC and ADC, respectively...
  33. ncbi request reprint [Pleural effusion complicating a totally implanted venous device]
    A Blanc
    Service de Pneumologie, Hopital de Hautepierre, Strasbourg, France
    Rev Mal Respir 23:363-6. 2006
    ..Totally implanted venous devices (TIVD) are an essential tool for repeated intravenous treatments such as chemotherapy for cancer and antibiotics for cystic fibrosis...
  34. ncbi request reprint [Sequential administration of a reduced dose of almitrine to patients with chronic obstructive bronchopneumopathies. A controlled multicenter study]
    E Weitzenblum
    Service de Pneumologie, Hopital de Hautepierre, CHRU, Strasbourg
    Rev Mal Respir 9:455-63. 1992
    ..001). The outcome of the neurological and electrophysiological assessments did not show any significant difference between the two groups.(ABSTRACT TRUNCATED AT 250 WORDS)..
  35. pmc Endoglin germline mutation in a patient with hereditary haemorrhagic telangiectasia and dexfenfluramine associated pulmonary arterial hypertension
    A Chaouat
    Service de Pneumologie, Hopital de Hautepierre, Strasbourg, France
    Thorax 59:446-8. 2004
    ..This report highlights the critical role of the TGF-beta signalling pathway in this condition...
  36. ncbi request reprint [Pulmonary artery hypertension]
    A Chaouat
    Service de Pneumologie, Hopital de Hautepierre, Strasbourg
    Rev Mal Respir 19:S61-74. 2002
  37. ncbi request reprint [Coagulation disorders and arterial thromboembolic events in non-small-cell lung cancer. A case report]
    A Blanc
    Service de Pneumologie, Hôpitaux Civils de Strasbourg, BP 426, 67091 Strasbourg Cedex
    Rev Pneumol Clin 60:175-9. 2004
    ..The role of anticancer chemotherapy as a favoring factor for thromboembolic events is also emphasized in patients with non-small-cell lung cancer...
  38. ncbi request reprint Dry powder ipratropium bromide is as safe and effective as metered-dose inhaler formulation: a cumulative dose-response study in chronic obstructive pulmonary disease patients
    Antoine Cuvelier
    Service de Pneumologie, Hopital de Bois Guillaume, CHU de Rouen 76031 Rouen Cedex, France
    Respir Care 47:159-66. 2002
    ..The new lactose powder formulation of ipratropium bromide inhaled via the breath-activated DPI is a safe and effective alternative to the chlorofluorocarbon-propelled MDI...
  39. ncbi request reprint [Use of linezolid for the treatment of lung infections in adults with cystic fibrosis]
    D Betton
    Service de Pharmacie, Hopital de Hautepierre, Hopitaux Universitaires de Strasbourg, Avenue Moliere, 67097 Strasbourg Cedex
    Rev Pneumol Clin 62:374-8. 2006
    ....
  40. doi request reprint Spontaneous short-term variations of circulating endothelin-1 in pulmonary hypertension
    Anne Charloux
    Transl Res 151:119-21. 2008
    ....
  41. ncbi request reprint Pulmonary arterial hypertension in France: results from a national registry
    Marc Humbert
    UPRES EA 2705, Service de Pneumologie et Reanimation Respiratoire, Hopital Antoine Beclere, Assistance Publique Hopitaux de Paris, Universite Paris Sud, 157 rue de la Porte de Trivaux, 92140 Clamart, France
    Am J Respir Crit Care Med 173:1023-30. 2006
    ..Pulmonary arterial hypertension (PAH) is an orphan disease for which the trend is for management in designated centers with multidisciplinary teams working in a shared-care approach...
  42. ncbi request reprint Severe pulmonary hypertension in COPD: is it a distinct disease?
    Emmanuel Weitzenblum
    Chest 127:1480-2. 2005
  43. ncbi request reprint Interleukin-6 gene polymorphism confers susceptibility to pulmonary hypertension in chronic obstructive pulmonary disease
    Saadia Eddahibi
    INSERM U492 and Département de Physiologie, Hôpital H Mondor, Creteil, France
    Proc Am Thorac Soc 3:475-476. 2006