Research Topics
Genomes and Genes | Michel J WeberSummaryCountry: France Publications
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Publications
Cooperative dimerization of the POU domain protein Brn-2 on a new motif activates the neuronal promoter of the human aromatic L-amino acid decarboxylase geneClaire Dugast-Darzacq
Laboratoire de Biologie Moleculaire Eucaryote, CNRS UMR 5099 IFR 109, 118 route de Narbonne, 31062, Cedex, Toulouse, France
Brain Res Mol Brain Res 120:151-63. 2004..By site directed mutagenesis of the POU domain of Brn-2, the dimerization interface on the TB element was localized to the hydrophobic pocket of the POU specific domain and the C-terminal part of the POU homeodomain...
New human and mouse microRNA genes found by homology searchMichel J Weber
Laboratoire de Biologie Moleculaire Eucaryote, UMR5099, CNRS and Université Paul Sabatier, IFR109, Toulouse, France
FEBS J 272:59-73. 2005..I also discuss the presence of human miRNAs in introns of paralogous genes and in miRNA clusters...
Mammalian small nucleolar RNAs are mobile genetic elementsMichel J Weber
Laboratoire de Biologie Moleculaire Eucaryote, CNRS Université de Toulouse Paul Sabatier, Toulouse, France
PLoS Genet 2:e205. 2006..I furthermore propose that retroposition followed by genetic drift is a mechanism that increased snoRNA diversity during vertebrate evolution to eventually acquire new RNA-modification functions...
snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAsLaurent Lestrade
, , 118 route de Narbonne, 31062 Toulouse Cedex, France
Nucleic Acids Res 34:D158-62. 2006..The database is available online at http://www-snorna.biotoul.fr/. It can also be accessed from the human UCSC Genome Browser via the sno/miRNA track...
