P Voisin

Summary

Country: France

Publications

  1. ncbi Is micronuclei yield variability a problem for overexposure dose assessment to ionizing radiation?
    N Paillole
    Institut de Protection et de Surete Nucleaire, Département de Protection de la santé de l Homme et de Dosimétrie, I P S N, Fontenay aux Roses, France
    Mutat Res 413:47-56. 1998
  2. ncbi Cytogenetic damage in lymphocytes for the purpose of dose reconstruction: a review of three recent radiation accidents
    A Wojcik
    Department of Radiation Biology and Health Protection, Institute of Nuclear Chemistry and Technology, Warszawa, Poland
    Cytogenet Genome Res 104:200-5. 2004
  3. ncbi Towards a standardization of biological dosimetry by cytogenetics
    P Voisin
    Institute of Protection and Nuclear Safety IPSN, Fontenay aux Roses, France
    Cell Mol Biol (Noisy-le-grand) 48:501-4. 2002
  4. ncbi Mathematical methods in biological dosimetry: the 1996 Iranian accident
    P Voisin
    Laboratoire de Dosimétrie Biologique Multiparamétrique, Institut de Protection et Sûreté Nucléaire, Fontenay aux Roses, France
    Int J Radiat Biol 76:1545-54. 2000
  5. ncbi The cytogenetic dosimetry of recent accidental overexposure
    P Voisin
    Laboratoire de Dosimétrie Biologique Multiparamétrique, Institut de Protection et Sûreté Nucléaire, IPSN, Fontenay aux Roses, France
    Cell Mol Biol (Noisy-le-grand) 47:557-64. 2001
  6. ncbi Radio-induced structural membrane modifications: a potential bioindicator of ionizing radiation exposure?
    M Benderitter
    Institut de Protection et de Surete Nucleaire, Département de Protection de la santé de l Homme et de Dosimétrie, Fontenay aux Roses, France
    Int J Radiat Biol 75:1043-53. 1999
  7. ncbi Study of the tools available in biological dosimetry to estimate the dose in cases of accidental complex overexposure to ionizing radiation: the Lilo accident
    L Roy
    Institute for Radiological Protection and Nuclear Safety IRSN, Fontenay aux Roses, France
    Int J Radiat Biol 82:39-48. 2006
  8. ncbi Is FISH painting an appropriate biological marker for dose estimates of suspected accidental radiation overexposure? A review of cases investigated in France from 1995 to 1996
    I Sorokine-Durm
    Institut de Protection et de Surete Nucleaire, Département de Protection de la santé de l Homme et de Dosimétrie, IPSN, Fontenay aux Roses, France
    Environ Health Perspect 105:1427-32. 1997
  9. ncbi Effects of chronic 137Cs ingestion on barrier properties of jejunal epithelium in rats
    I Dublineau
    Institut de Radioprotection et de Surete Nucleaire, Direction de la RadioProtection de l Homme, Service de Radiobiologie et d Epidemiologie, Laboratoire de Radiotoxicologie Experimentale, Fontenay aux Roses, France
    J Toxicol Environ Health A 70:810-9. 2007
  10. ncbi A new image analysis system for biological dosimetry by fluorescent in situ hybridization. Step 1: metaphase finder and automatic metaphase acquisition validation
    L Roy
    Institut de Protection et de Surete Nucleaire, Département de Protection de la santé de I Homme et de Dosimétrie, IPSN, Fontenay aux Roses, France
    J Radiat Res 42:165-77. 2001

Collaborators

Detail Information

Publications25

  1. ncbi Is micronuclei yield variability a problem for overexposure dose assessment to ionizing radiation?
    N Paillole
    Institut de Protection et de Surete Nucleaire, Département de Protection de la santé de l Homme et de Dosimétrie, I P S N, Fontenay aux Roses, France
    Mutat Res 413:47-56. 1998
    ..32 gy...
  2. ncbi Cytogenetic damage in lymphocytes for the purpose of dose reconstruction: a review of three recent radiation accidents
    A Wojcik
    Department of Radiation Biology and Health Protection, Institute of Nuclear Chemistry and Technology, Warszawa, Poland
    Cytogenet Genome Res 104:200-5. 2004
    ..In the present paper the approaches chosen to estimate, by cytogenetic methods, the doses absorbed by the people involved in the accidents are described...
  3. ncbi Towards a standardization of biological dosimetry by cytogenetics
    P Voisin
    Institute of Protection and Nuclear Safety IPSN, Fontenay aux Roses, France
    Cell Mol Biol (Noisy-le-grand) 48:501-4. 2002
    ..On the basis of a group consensus, a text defining minimal constraints on all the steps of the process was proposed. A working draft was submitted to ISO in 2001 and its structure is presented here...
  4. ncbi Mathematical methods in biological dosimetry: the 1996 Iranian accident
    P Voisin
    Laboratoire de Dosimétrie Biologique Multiparamétrique, Institut de Protection et Sûreté Nucléaire, Fontenay aux Roses, France
    Int J Radiat Biol 76:1545-54. 2000
    ..To report 18 months of cytogenetic follow-up for an Iranian worker accidentally overexposed to 192Ir, the mathematical extrapolation and comparison with clinical data...
  5. ncbi The cytogenetic dosimetry of recent accidental overexposure
    P Voisin
    Laboratoire de Dosimétrie Biologique Multiparamétrique, Institut de Protection et Sûreté Nucléaire, IPSN, Fontenay aux Roses, France
    Cell Mol Biol (Noisy-le-grand) 47:557-64. 2001
    ....
  6. ncbi Radio-induced structural membrane modifications: a potential bioindicator of ionizing radiation exposure?
    M Benderitter
    Institut de Protection et de Surete Nucleaire, Département de Protection de la santé de l Homme et de Dosimétrie, Fontenay aux Roses, France
    Int J Radiat Biol 75:1043-53. 1999
    ..This study focused on radio-induced membrane alterations in order to assess some related parameters as potential biological indicators of ionizing radiation effects in cases of accidental overexposure...
  7. ncbi Study of the tools available in biological dosimetry to estimate the dose in cases of accidental complex overexposure to ionizing radiation: the Lilo accident
    L Roy
    Institute for Radiological Protection and Nuclear Safety IRSN, Fontenay aux Roses, France
    Int J Radiat Biol 82:39-48. 2006
    ..To compare the efficiency of different cytogenetic tools in estimating the doses received by four people involved in the Lilo accident and to monitor the dose estimate over 4.5 years...
  8. ncbi Is FISH painting an appropriate biological marker for dose estimates of suspected accidental radiation overexposure? A review of cases investigated in France from 1995 to 1996
    I Sorokine-Durm
    Institut de Protection et de Surete Nucleaire, Département de Protection de la santé de l Homme et de Dosimétrie, IPSN, Fontenay aux Roses, France
    Environ Health Perspect 105:1427-32. 1997
    ..We describe their similarities or differences and discuss the suitability of using FISH painting for routine expertise analysis...
  9. ncbi Effects of chronic 137Cs ingestion on barrier properties of jejunal epithelium in rats
    I Dublineau
    Institut de Radioprotection et de Surete Nucleaire, Direction de la RadioProtection de l Homme, Service de Radiobiologie et d Epidemiologie, Laboratoire de Radiotoxicologie Experimentale, Fontenay aux Roses, France
    J Toxicol Environ Health A 70:810-9. 2007
    ....
  10. ncbi A new image analysis system for biological dosimetry by fluorescent in situ hybridization. Step 1: metaphase finder and automatic metaphase acquisition validation
    L Roy
    Institut de Protection et de Surete Nucleaire, Département de Protection de la santé de I Homme et de Dosimétrie, IPSN, Fontenay aux Roses, France
    J Radiat Res 42:165-77. 2001
    ..The protocols for the detection of translocations may now be applied for biological dosimetry. This step will be validated in a future study...
  11. ncbi Clearance of radiation-induced apoptotic lymphocytes: ex vivo studies and an in vitro co-culture model
    M Benderitter
    Institut de Protection et de Surete Nucleaire, Département de Protection de la santé de l Homme et de Dosimétrie, Laboratoire de Dosimétrie Biologique Multiparamétrique, F 92265 Fontenay aux Roses Cedex, France
    Radiat Res 158:464-74. 2002
    ..We propose the measurement of apoptosis in lymphocytes as a potential short-term biomarker of ionizing radiation exposure...
  12. ncbi Simultaneous analysis of radio-induced membrane alteration and cell viability by flow cytometry
    M Benderitter
    Institut de Protection et de Surete Nucleaire, IPSN, Fontenay aux Roses, France
    Cytometry 39:151-7. 2000
    ..Modifications of intracellular transfer, resulting from a loss of membrane integrity may contribute toward setting the cell onto the pathway of apoptosis...
  13. ncbi Biochemical indicators of whole-body gamma-radiation effects in the pig
    M Donnadieu-Claraz
    Institut de Protection et de Surete Nucleaire, Département de Protection de la santé de l Homme et de Dosimétrie, IPSN, Fontenay aux Roses, France
    Int J Radiat Biol 75:165-74. 1999
    ..Validation of the pig as an experimental animal model for dose assessment after ionizing irradiation...
  14. ncbi New approach for dose reconstruction: application to one case of localized irradiation with radiological burns
    J F Bottollier-Depois
    Institute for Protection and Nuclear Safety, IPSN, Fontenay aux Roses, France
    Health Phys 79:251-6. 2000
    ....
  15. ncbi Effect of acetaminophen administration to rats chronically exposed to depleted uranium
    Y Gueguen
    Institute for Radiological Protection and Nuclear Safety, Radiological Protection and Human Health Division, Radiobiology and Epidemiology Department, Laboratory of Experimental Toxicology, Fontenay aux Roses, France
    Toxicology 229:62-72. 2007
    ..These results could explain the worse elimination of APAP in the plasma and confirm our hypothesis of a modification of the drug metabolism following a DU chronic contamination...
  16. ncbi Potential role of the membrane in the development of intestinal cellular damage after whole-body gamma irradiation of the rat
    F Lebrun
    Institut de Radioprotection et de Surete Nucleaire, Département de Protection de la santé de l Homme et de Dosimdtrie, Fontenay aux Roses, France
    Can J Physiol Pharmacol 80:686-93. 2002
    ..Thus, total body irradiation induces changes in intestinal membrane fluidity and an increase in lipoperoxidation. These modifications may have an impact on the activity of membrane proteins involved in intestinal function...
  17. ncbi PCC-FISH in skin fibroblasts for local dose assessment: biodosimetric analysis of a victim of the Georgian radiological accident
    J P Pouget
    Institut de Radioprotection et de Surete Nucleaire, Direction de la RadioProtection de l Homme, 92262 Fontenay aux Roses, France
    Radiat Res 162:365-76. 2004
    ..To assess its worth, this approach needs to be extended to future accidents involving localized radiation exposure...
  18. ncbi Criticality accident dosimetry by chromosomal analysis
    P Voisin
    Institute of Radiation and Nuclear Safety, Fontenay-aux-Roses, 92265, France
    Radiat Prot Dosimetry 110:443-7. 2004
    ..The main reason for the higher values was the calibration relationships for fission neutrons...
  19. ncbi International intercomparison for criticality dosimetry: the case of biological dosimetry
    L Roy
    Institut de Radioprotection et de Surete Nucleaire, Direction de la RadioProtection de l Homme, IRSN, BP 17 92262 Fontenay aux Roses, France
    Radiat Prot Dosimetry 110:471-6. 2004
    ..The evaluation of the respective gamma and neutron dose was achieved only by four laboratories, with some small variations among them...
  20. ncbi Micro-organisation of the membrane after radiation-induced apoptosis: a flow cytometry study
    L Vincent-Genod
    , , Fontenay-aux-Roses, France
    Radiat Environ Biophys 40:213-9. 2001
    ..Our observations support the specificity of radiation-induced apoptosis compared to spontaneous apoptosis in terms of biophysical modifications of membrane properties...
  21. ncbi Translocation yields in peripheral blood lymphocytes from control populations
    C A Whitehouse
    Westlakes Research Institute, Cumbria, UK
    Int J Radiat Biol 81:139-45. 2005
    ..CONCLUSIONS: For retrospective biological dosimetry purposes a generic age-dependent control level can be assumed. No other lifestyle factors such as smoking appear to have a significant effect on translocation yield...
  22. ncbi Review of translocations detected by FISH for retrospective biological dosimetry applications
    A A Edwards
    Health Protection Agency, Radiation Protection Division HPA, Chilton, Didcot, Oxon OX11 0RQ, UK
    Radiat Prot Dosimetry 113:396-402. 2005
    ..5 Gy above normal background levels can be measured for any individual. The main application is considered to provide an independent verification of lifetime doses to individuals who might form a part of an epidemiological study...
  23. ncbi The cell membrane as a biosensor of oxidative stress induced by radiation exposure: a multiparameter investigation
    M Benderitter
    Département de Protection de la santé de l Homme et de Dosimétrie, IRSN, BP no 17, F 92262 Fontenay aux Roses Cedex, France
    Radiat Res 159:471-83. 2003
    ..Thus the role of the biological membrane in the expression and course of cell damage after radiation exposure must be considered...
  24. ncbi Spatial and temporal control of transgene expression in vivo using a heat-sensitive promoter and MRI-guided focused ultrasound
    E Guilhon
    , , Bordeaux, France
    J Gene Med 5:333-42. 2003
    ..Induced expression was also clearly shown for temperature in the range 44-48 degrees C but not at 42 degrees C. CONCLUSIONS: Heating with MRI-FUS allows a tight and non-invasive control of transgene expression in a tumour...
  25. ncbi Biological estimates of dose to inhabitants of Belarus and Ukraine following the Chernobyl accident
    A Edwards
    National Radiological Protection Board, Chilton, Didcot, Oxon OX11 0RQ, UK
    Radiat Prot Dosimetry 111:211-9. 2004
    ..All other assays showed inconsistency from person to person or other variations apparently not related to dose. The measurement of translocations, it is concluded, is the biological method of choice for retrospective dosimetry...