J Velours

Summary

Country: France

Publications

  1. doi request reprint Mitochondrial F1F0-ATP synthase and organellar internal architecture
    Jean Velours
    Universite Bordeaux 2, CNRS, Institut de Biochimie et Génétique Cellulaires, 1 rue Camille Saint Saens, 33077 Bordeaux Cedex, France
    Int J Biochem Cell Biol 41:1783-9. 2009
  2. ncbi request reprint The Saccharomyces cerevisiae ATP synthase
    J Velours
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux, France
    J Bioenerg Biomembr 32:383-90. 2000
  3. ncbi request reprint Bovine coupling factor 6, with just 14.5% shared identity, replaces subunit h in the yeast ATP synthase
    J Velours
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux 2, 1 rue Camille Saint Saens, 33077 Bordeaux, Cedex France
    J Biol Chem 276:8602-7. 2001
  4. ncbi request reprint Organisation of the yeast ATP synthase F(0):a study based on cysteine mutants, thiol modification and cross-linking reagents
    J Velours
    Institut de Biochimie et Genetique Cellulaires du CNRS, 1 rue Camille Saint Saens, 33077, Cedex, Bordeaux, France
    Biochim Biophys Acta 1458:443-56. 2000
  5. ncbi request reprint Topography of the yeast ATP synthase F0 sector
    J Velours
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite de Bordeaux II, France
    Biochimie 80:793-801. 1998
  6. ncbi request reprint The subunit f of mitochondrial yeast ATP synthase--characterization of the protein and disruption of the structural gene ATP17
    C Spannagel
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux 2, France
    Eur J Biochem 247:1111-7. 1997
  7. ncbi request reprint Environmental study of subunit i, a F(o) component of the yeast ATP synthase
    P Paumard
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux 2, 1 rue Camille Saint Saens, 33077 Bordeaux Cedex, France
    Biochemistry 39:4199-205. 2000
  8. ncbi request reprint ATP synthase of yeast mitochondria. Isolation of the subunit h and disruption of the ATP14 gene
    G Arselin
    Institut de Biochimie et Génétique Cellulaires du Centre National de la Recherche Scientifique, Universite de Bordeaux II, 1 rue Camille Saint Saens, 33077 Bordeaux Cedex, France
    J Biol Chem 271:20284-90. 1996
  9. ncbi request reprint Identification of a nuclear gene (FMC1) required for the assembly/stability of yeast mitochondrial F(1)-ATPase in heat stress conditions
    L Lefebvre-Legendre
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux 2, 33077 Bordeaux Cedex, France
    J Biol Chem 276:6789-96. 2001
  10. ncbi request reprint Isolation of supernumerary yeast ATP synthase subunits e and i. Characterization of subunit i and disruption of its structural gene ATP18
    J Vaillier
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux 2, 33077 Bordeaux Cedex, France
    J Biol Chem 274:543-8. 1999

Collaborators

  • D M Mueller
  • N Camougrand
  • Alain Dautant
  • T Michon
  • Isabelle Sagot
  • C Lemaire
  • J Vaillier
  • G Arselin
  • P V Graves
  • C Spannagel
  • N Sergeant
  • L Lefebvre-Legendre
  • P Paumard
  • M Galván-valencia
  • J C Michalski
  • A Delacourte
  • J Lemoine
  • R Mena-Lopez
  • A Ghestem
  • J P David
  • J Dachary
  • A Wattez
  • J P Mazat
  • P E Sautiere
  • P P Slonimski
  • H Benabdelhak
  • J P di Rago
  • D Brethes
  • C Napias
  • M F Paul
  • B Guerin
  • S Chaignepain
  • D Razaka-Jolly
  • M F Giraud
  • M Rigoulet
  • E Guelin
  • S Ackerman
  • J Yue
  • A Tzagolof
  • S Ackermann S [corrected to Ackerman
  • J Chevallier
  • N Norais
  • G Arselin de Chateaubodeau
  • D Prome
  • J C Gandar
  • M Aigle

Detail Information

Publications23

  1. doi request reprint Mitochondrial F1F0-ATP synthase and organellar internal architecture
    Jean Velours
    Universite Bordeaux 2, CNRS, Institut de Biochimie et Génétique Cellulaires, 1 rue Camille Saint Saens, 33077 Bordeaux Cedex, France
    Int J Biochem Cell Biol 41:1783-9. 2009
    ..This paper reviews the ATP synthase components whose modifications lead to anomalous mitochondrial morphology and also provides a schema showing the formation of the so-called onion-like structures...
  2. ncbi request reprint The Saccharomyces cerevisiae ATP synthase
    J Velours
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux, France
    J Bioenerg Biomembr 32:383-90. 2000
    ..This review summarizes data on yeast ATP synthase obtained in our laboratory since 1980...
  3. ncbi request reprint Bovine coupling factor 6, with just 14.5% shared identity, replaces subunit h in the yeast ATP synthase
    J Velours
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux 2, 1 rue Camille Saint Saens, 33077 Bordeaux, Cedex France
    J Biol Chem 276:8602-7. 2001
    ..Like subunit h, bovine F(6) is shown to interact mainly with subunit 4 (subunit b), a component of the second stalk of the enzyme. These data indicated the subunit h is the yeast homolog of mammalian coupling factor F(6)...
  4. ncbi request reprint Organisation of the yeast ATP synthase F(0):a study based on cysteine mutants, thiol modification and cross-linking reagents
    J Velours
    Institut de Biochimie et Genetique Cellulaires du CNRS, 1 rue Camille Saint Saens, 33077, Cedex, Bordeaux, France
    Biochim Biophys Acta 1458:443-56. 2000
    ..The dimerisation of subunit 4 in the membrane revealed that this component is located in the periphery of the enzyme and interacts with other ATP synthase complexes...
  5. ncbi request reprint Topography of the yeast ATP synthase F0 sector
    J Velours
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite de Bordeaux II, France
    Biochimie 80:793-801. 1998
    ....
  6. ncbi request reprint The subunit f of mitochondrial yeast ATP synthase--characterization of the protein and disruption of the structural gene ATP17
    C Spannagel
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux 2, France
    Eur J Biochem 247:1111-7. 1997
    ..The null mutant mitochondria were devoid of oligomycin-sensitive ATPase, but still contained an active F1, while the subunits f, 6 and 8 were absent...
  7. ncbi request reprint Environmental study of subunit i, a F(o) component of the yeast ATP synthase
    P Paumard
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux 2, 1 rue Camille Saint Saens, 33077 Bordeaux Cedex, France
    Biochemistry 39:4199-205. 2000
    ....
  8. ncbi request reprint ATP synthase of yeast mitochondria. Isolation of the subunit h and disruption of the ATP14 gene
    G Arselin
    Institut de Biochimie et Génétique Cellulaires du Centre National de la Recherche Scientifique, Universite de Bordeaux II, 1 rue Camille Saint Saens, 33077 Bordeaux Cedex, France
    J Biol Chem 271:20284-90. 1996
    ..The mutant mitochondria did not contain subunit h, and the mitochondrially encoded hydrophobic subunit 6 was not present...
  9. ncbi request reprint Identification of a nuclear gene (FMC1) required for the assembly/stability of yeast mitochondrial F(1)-ATPase in heat stress conditions
    L Lefebvre-Legendre
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux 2, 33077 Bordeaux Cedex, France
    J Biol Chem 276:6789-96. 2001
    ..However, unlike Atp12p and Atp11p, Fmc1p is not required in normal growth conditions (28--30 degrees C). We propose that Fmc1p is required for the proper folding/stability or functioning of Atp12p in heat stress conditions...
  10. ncbi request reprint Isolation of supernumerary yeast ATP synthase subunits e and i. Characterization of subunit i and disruption of its structural gene ATP18
    J Vaillier
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite Victor Segalen, Bordeaux 2, 33077 Bordeaux Cedex, France
    J Biol Chem 274:543-8. 1999
    ....
  11. ncbi request reprint Topography of the yeast ATP synthase F0 sector by using cysteine substitution mutants. Cross-linkings between subunits 4, 6, and f
    C Spannagel
    Institut de Biochimie et Genetique Cellulaires du CNRS, Universite de Bordeaux II, 1 rue Camille Saint Saens, 33077 Bordeaux Cedex, France
    Biochemistry 37:615-21. 1998
    ....
  12. ncbi request reprint NH2-terminal sequence of the isolated yeast ATP synthase subunit 6 reveals post-translational cleavage
    T Michon
    Institut de Biochimie Cellulaire et Neurochimie du CNRS, Bordeaux, France
    Eur J Biochem 172:621-5. 1988
    ..Thus, mature subunit 6 contains 249 amino acid residues and displays a molecular mass of 27943 Da...
  13. ncbi request reprint ATP4, the structural gene for yeast F0F1 ATPase subunit 4
    J Velours
    Institut de Biochimie Cellulaire et de Neurochimie du Centre National de la Recherche Scientifique, Bordeaux, France
    Eur J Biochem 170:637-42. 1988
    ..This subunit presents amphiphilic behaviour with two distinct domains. A high alpha-helix content of 77% was predicted from the sequence. Subunit 4 shows homology with the b subunit of Escherichia coli ATP synthase...
  14. ncbi request reprint Isolation and complete amino acid sequence of the mitochondrial ATP synthase epsilon-subunit of the yeast Saccharomyces cerevisiae
    G Arselin
    Institut de Biochimie Cellulaire et Neurochimie, Universite de Bordeaux II, France
    J Biol Chem 266:723-7. 1991
    ..This polypeptide is rather basic since it contains 7 basic residues and 3 acidic residues. This study shows a slight similarity with the bovine epsilon-subunit ATP synthase since there are 16 identical residues...
  15. ncbi request reprint The yeast ATP synthase subunit 4: structure and function
    J Velours
    Institut de Biochimie Cellulaire et Neurochimie du CNRS, Universite de Bordeaux, France
    Biochimie 71:903-15. 1989
    ..This mutant is devoid of oxidative phosphorylation and F1 is loosely bound to the membrane. Our data are in favor of a structural relationship between subunit 4 and the mitochondrially-translated subunit 6 during biogenesis of F0...
  16. ncbi request reprint Absence of the mitochondrial AAA protease Yme1p restores F0-ATPase subunit accumulation in an oxa1 deletion mutant of Saccharomyces cerevisiae
    C Lemaire
    Centre de Génétique Moléculaire du CNRS, Avenue de la Terrasse, 91198 Gif sur Yvette Cedex, France
    J Biol Chem 275:23471-5. 2000
    ..In addition, although respiratory function is dispensable in Saccharomyces cerevisiae, we show that the simultaneous inactivation of AFG3 and YME1 is lethal and that the essential function does not reside in their protease activity...
  17. ncbi request reprint Association of ATP synthase alpha-chain with neurofibrillary degeneration in Alzheimer's disease
    N Sergeant
    Unite INSERM 422, 1, Place de Verdun, Lille Cedex 59045, France
    Neuroscience 117:293-303. 2003
    ..This regulatory subunit of the respiratory complex V of mitochondria is thus a potential target for therapeutic and diagnostic strategies...
  18. ncbi request reprint The role of subunit 4, a nuclear-encoded protein of the F0 sector of yeast mitochondrial ATP synthase, in the assembly of the whole complex
    M F Paul
    Institut de Biochimie Cellulaire et Neurochimie du Centre National de la Recherche Scientifique, Universite de Bordeaux, France
    Eur J Biochem 185:163-71. 1989
    ..Thus, the cytochrome oxidase activity of the mutant strain was about five times lower than that of the wild type. In addition, a high percentage of spontaneous rho- mutants was detected...
  19. ncbi request reprint Cloning of the yeast ATP3 gene coding for the gamma-subunit of F1 and characterization of atp3 mutants
    M F Paul
    Department of Biological Sciences, Columbia University, New York, New York 10027
    J Biol Chem 269:26158-64. 1994
    ..This is not true of C287/LU1, which was found to assemble an F1-F0 complex. These data indicate that the yeast gamma-subunit has dual functions, one in catalysis of ATP hydrolysis/synthesis and the second in assembly/stability of F1...
  20. ncbi request reprint ATP synthase of yeast mitochondria. Isolation and disruption of the ATP epsilon gene
    E Guelin
    Institut de Biochimie Cellulaire, Universite de Bordeaux II, France
    J Biol Chem 268:161-7. 1993
    ..The catalytic sector appeared unstable during purification but F0-subunits were still bound to F1. The mutation promoted a highly oligomycin-sensitive uncoupling of the mitochondrial respiration rate...
  21. ncbi request reprint Mutation in the hydrophobic domain of ATP synthase subunit 4 (subunit b) of yeast mitochondria disturbs coupling between proton translocation and catalysis
    D Razaka-Jolly
    Institut de Biochimie et Génétique Cellulaires du Centre National de la Recherche Scientifique, Universite de Bordeaux II, France
    Biochemistry 33:9684-91. 1994
    ..From these results, we propose that the dicyclohexylcarbodiimide inhibition site is located upstream of the oligomycin inhibition site when considering the proton flux occurring during ATP synthesis...
  22. ncbi request reprint ATP synthase of yeast mitochondria. Isolation of the F1 delta subunit, sequence and disruption of the structural gene
    M F Giraud
    Institut de Biochimie et Génétique Cellulaire, Centre National de la Recherche Scientifique, Universite de Bordeaux II, France
    Eur J Biochem 222:851-9. 1994
    ..The double mutant (rho-, ATP delta::URA3) displayed low or no ATPase activity with an unstable catalytic sector, since a polyclonal antibody directed against the beta subunit did not coprecipitate the alpha subunit...
  23. ncbi request reprint ATP synthase of yeast mitochondria. Characterization of subunit d and sequence analysis of the structural gene ATP7
    N Norais
    Institut de Biochimie Cellulaire et Neurochimie, Centre National de la Recherche Scientifique CNRS, Universite de Bordeaux II, France
    J Biol Chem 266:16541-9. 1991
    ..The mutant mitochondria did not contain subunit d, and the mitochondrially encoded hydrophobic subunit 6 was not present...