Francis Vasseur

Summary

Country: France

Publications

  1. pmc The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn's disease
    Francis Vasseur
    Universite Lille Nord de France, 59000, Lille, France
    BMC Med Genet 14:35. 2013
  2. doi request reprint Variants of NOD1 and NOD2 genes display opposite associations with familial risk of Crohn's disease and anti-saccharomyces cerevisiae antibody levels
    Francis Vasseur
    Univ Nord de France, France
    Inflamm Bowel Dis 18:430-8. 2012
  3. doi request reprint Concordance of two multiple analytical approaches demonstrate that interaction between BMI and ADIPOQ haplotypes is a determinant of LDL cholesterol in a general French population
    Francis Vasseur
    Biostatistics Department EA2694, University Hospital, University Lille Nord de France, UDSL, Lille Cedex, France
    J Hum Genet 55:227-31. 2010
  4. pmc Analysis of sequence variability in the CART gene in relation to obesity in a Caucasian population
    Audrey Guerardel
    Institute of Biology CNRS UMR 8090, Pasteur Institute, Lille, France
    BMC Genet 6:19. 2005
  5. doi request reprint Long-term outcome of treatment with infliximab in pediatric-onset Crohn's disease: a population-based study
    Valérie Crombé
    Gastroenterology Unit, EPIMAD Registry, Lille University Hospital, Lille, France
    Inflamm Bowel Dis 17:2144-52. 2011
  6. doi request reprint Mortality and cancer in pediatric-onset inflammatory bowel disease: a population-based study
    Anaïs Peneau
    Gastroenterology Unit, Lille University Nord de France, CHU Lille and Lille 2 University, Lille, France
    Am J Gastroenterol 108:1647-53. 2013
  7. ncbi request reprint Distinct impaired regulation of SOCS3 and long and short isoforms of the leptin receptor in visceral and subcutaneous fat of lean and obese women
    Karin Séron
    CNRS 8090 Institut de Biologie de Lille, Institut Pasteur, Lille, France
    Biochem Biophys Res Commun 348:1232-8. 2006
  8. ncbi request reprint Adiponectin, type 2 diabetes and the metabolic syndrome: lessons from human genetic studies
    Francis Vasseur
    Biostatistics Department Medical School and Public Health Clinics, University Hospital, Lille, France
    Expert Rev Mol Med 8:1-12. 2006
  9. pmc GAD2 on chromosome 10p12 is a candidate gene for human obesity
    Philippe Boutin
    Institute of Biology Centre National de la Recherche Scientifique, Pasteur Institute, Lille, France
    PLoS Biol 1:E68. 2003
  10. doi request reprint MBNL1 gene variants as modifiers of disease severity in myotonic dystrophy type 1
    Vincent Huin
    Inserm UMR837, Alzheimer and Tauopathies, University Lille Nord de France, USDL, IMPRT, Jean Pierre Aubert Research Center, Bâtiment Biserte, 1, Place de Verdun, 59045 Lille, France
    J Neurol 260:998-1003. 2013

Collaborators

Detail Information

Publications13

  1. pmc The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn's disease
    Francis Vasseur
    Universite Lille Nord de France, 59000, Lille, France
    BMC Med Genet 14:35. 2013
    ..In mice, anti-glucan antibody response depends on the NLRP3 inflammasome. Here, we explored the effect of mutated CARD8, a component of the inflammasome, on anti-glycans antibody response in human...
  2. doi request reprint Variants of NOD1 and NOD2 genes display opposite associations with familial risk of Crohn's disease and anti-saccharomyces cerevisiae antibody levels
    Francis Vasseur
    Univ Nord de France, France
    Inflamm Bowel Dis 18:430-8. 2012
    ....
  3. doi request reprint Concordance of two multiple analytical approaches demonstrate that interaction between BMI and ADIPOQ haplotypes is a determinant of LDL cholesterol in a general French population
    Francis Vasseur
    Biostatistics Department EA2694, University Hospital, University Lille Nord de France, UDSL, Lille Cedex, France
    J Hum Genet 55:227-31. 2010
    ..13, 95% CI=2.20-4.46, P<0.0001). Our results suggest that in interaction with BMI, ADIPOQ haplotypes capture genetic variation(s) from neighboring gene(s) that would modulate LDL-C level...
  4. pmc Analysis of sequence variability in the CART gene in relation to obesity in a Caucasian population
    Audrey Guerardel
    Institute of Biology CNRS UMR 8090, Pasteur Institute, Lille, France
    BMC Genet 6:19. 2005
    ..The aim of this study was to evaluate the effect of polymorphisms within the CART gene with regards to a possible association with obesity in a Caucasian population...
  5. doi request reprint Long-term outcome of treatment with infliximab in pediatric-onset Crohn's disease: a population-based study
    Valérie Crombé
    Gastroenterology Unit, EPIMAD Registry, Lille University Hospital, Lille, France
    Inflamm Bowel Dis 17:2144-52. 2011
    ..We examined short- and long-term benefits and safety of infliximab (IFX) in a population-based cohort of Crohn's disease (CD) patients <17 years old at diagnosis...
  6. doi request reprint Mortality and cancer in pediatric-onset inflammatory bowel disease: a population-based study
    Anaïs Peneau
    Gastroenterology Unit, Lille University Nord de France, CHU Lille and Lille 2 University, Lille, France
    Am J Gastroenterol 108:1647-53. 2013
    ..Although the incidence of pediatric inflammatory bowel disease (IBD) continues to rise in Northern France, the risks of death and cancer in this population have not been characterized...
  7. ncbi request reprint Distinct impaired regulation of SOCS3 and long and short isoforms of the leptin receptor in visceral and subcutaneous fat of lean and obese women
    Karin Séron
    CNRS 8090 Institut de Biologie de Lille, Institut Pasteur, Lille, France
    Biochem Biophys Res Commun 348:1232-8. 2006
    ....
  8. ncbi request reprint Adiponectin, type 2 diabetes and the metabolic syndrome: lessons from human genetic studies
    Francis Vasseur
    Biostatistics Department Medical School and Public Health Clinics, University Hospital, Lille, France
    Expert Rev Mol Med 8:1-12. 2006
    ..Several of these variations additively contribute to the modulation of adiponectin level and function, and associate with insulin sensitivity, type 2 diabetes and vascular complications of obesity...
  9. pmc GAD2 on chromosome 10p12 is a candidate gene for human obesity
    Philippe Boutin
    Institute of Biology Centre National de la Recherche Scientifique, Pasteur Institute, Lille, France
    PLoS Biol 1:E68. 2003
    ..01, respectively). These data support the hypothesis of the orexigenic effect of GABA in humans and of a contribution of genes involved in GABA metabolism in the modulation of food intake and in the development of morbid obesity...
  10. doi request reprint MBNL1 gene variants as modifiers of disease severity in myotonic dystrophy type 1
    Vincent Huin
    Inserm UMR837, Alzheimer and Tauopathies, University Lille Nord de France, USDL, IMPRT, Jean Pierre Aubert Research Center, Bâtiment Biserte, 1, Place de Verdun, 59045 Lille, France
    J Neurol 260:998-1003. 2013
    ..0034) and accounted for 1.88 % of the variance in disease severity. We report the association of several genetic variants of the MBNL1 gene with DM1 or with the severity of the disease...
  11. ncbi request reprint A CD36 nonsense mutation associated with insulin resistance and familial type 2 diabetes
    Frederic Lepretre
    CNRS 8090 Institute of Biology, Pasteur Institute, Lille, France
    Hum Mutat 24:104. 2004
    ..Furthermore, expression studies of the truncated protein showed a defective binding of acetylated-LDL. Thus, our findings suggest a possible role for CD36 in the pathogenesis of T2D associated with reduced insulin sensitivity...
  12. ncbi request reprint Positional candidate gene analysis of Lim domain homeobox gene (Isl-1) on chromosome 5q11-q13 in a French morbidly obese population suggests indication for association with type 2 diabetes
    Mouna Barat-Houari
    Institute of Biology, Centre National de la Recherche Scientifique CNRS 80 90, Lille, France
    Diabetes 51:1640-3. 2002
    ..However, in French Caucasian morbidly obese subjects, the Isl1-47A-->G SNP may modulate the risk for type 2 diabetes and may increase body weight in diabetic morbidly obese subjects...
  13. doi request reprint Nutritional status and growth in pediatric Crohn's disease: a population-based study
    Francis Vasseur
    pôle de santé publique, Parc Eurasante, University Hospital, Université de Lille 2 EA2694, Lille Cedex, France
    Am J Gastroenterol 105:1893-900. 2010
    ..We examined nutritional and growth parameters from diagnosis to maximal follow-up in a population-based pediatric cohort, and we determined predictive factors...