Fabien Vanden Abeele

Summary

Country: France

Publications

  1. ncbi request reprint Ribosome-translocon complex mediates calcium leakage from endoplasmic reticulum stores
    Fabien Van Coppenolle
    Laboratoire de Physiologie Cellulaire, INSERM EMI 0228, Universite de Lille 1, Batiment SN3, 59655 Villeneuve d Ascq cedex, France
    J Cell Sci 117:4135-42. 2004
  2. ncbi request reprint Pharmacological effects of the lipidosterolic extract of Serenoa repens (Permixon) on rat prostate hyperplasia induced by hyperprolactinemia: comparison with finasteride
    F Van Coppenolle
    Laboratoire de Physiologie Cellulaire, USTL, INSERM EPI 9938, Villeneuve d Ascq, France
    Prostate 43:49-58. 2000
  3. ncbi request reprint Effects of hyperprolactinemia on rat prostate growth: evidence of androgeno-dependence
    F Van Coppenolle
    Laboratoire de Physiologie Cellulaire, Institut National de la Santé et de la Recherche Médicale INSERM EPI 9938, 59655 Villeneuve d Ascq, France
    Am J Physiol Endocrinol Metab 280:E120-9. 2001
  4. ncbi request reprint Two types of store-operated Ca2+ channels with different activation modes and molecular origin in LNCaP human prostate cancer epithelial cells
    Fabien Vanden Abeele
    Laboratoire de Physiologie Cellulaire, INSERM EMI 0228, Universite des Sciences et Technologies de Lille, Bat SN3, 59655 Villeneuve d Ascq, France
    J Biol Chem 279:30326-37. 2004
  5. ncbi request reprint Bcl-2-dependent modulation of Ca(2+) homeostasis and store-operated channels in prostate cancer cells
    Fabien Vanden Abeele
    Laboratoire de Physiologie Cellulaire, INSERM EPI 9938, Universite des Sciences et Technologies de Lille, Batiment SN3, 59655 Villeneuve d Ascq cedex, France
    Cancer Cell 1:169-79. 2002
  6. ncbi request reprint Store-operated Ca2+ current in prostate cancer epithelial cells. Role of endogenous Ca2+ transporter type 1
    Fabien Vanden Abeele
    Laboratoire de Physiologie Cellulaire, INSERM EMI 0228, Batiment SN3, USTL, 59655 Villeneuve d Ascq, France
    J Biol Chem 278:15381-9. 2003
  7. pmc Cytoskeleton reorganization as an alternative mechanism of store-operated calcium entry control in neuroendocrine-differentiated cells
    Karine Vanoverberghe
    INSERM, U 1003, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villeneuve d Ascq, France
    PLoS ONE 7:e45615. 2012
  8. pmc TRPV2 mediates adrenomedullin stimulation of prostate and urothelial cancer cell adhesion, migration and invasion
    Agathe Oulidi
    Inserm U1003, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villeneuve d Ascq, France
    PLoS ONE 8:e64885. 2013
  9. ncbi request reprint Complex modulation of the cold receptor TRPM8 by volatile anaesthetics and its role in complications of general anaesthesia
    Fabien Vanden Abeele
    Inserm U1003, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Laboratory of Excellence, Ion Channels Science and Therapeutics Université des Sciences et Technologies de Lille USTL, Villeneuve d Ascq, France
    J Cell Sci 126:4479-89. 2013
  10. doi request reprint Lysophospholipids stimulate prostate cancer cell migration via TRPV2 channel activation
    Michael Monet
    INSERM, U 800, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villeneuve d Ascq, F 59655 France Université des Sciences et Technologies de Lille USTL, Villeneuve d Ascq, F 59655, France
    Biochim Biophys Acta 1793:528-39. 2009

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Ribosome-translocon complex mediates calcium leakage from endoplasmic reticulum stores
    Fabien Van Coppenolle
    Laboratoire de Physiologie Cellulaire, INSERM EMI 0228, Universite de Lille 1, Batiment SN3, 59655 Villeneuve d Ascq cedex, France
    J Cell Sci 117:4135-42. 2004
    ..This work reveals a new role for the translocon which is involved in the control of the [Ca(2+)](ER) and could therefore supervise many physiological processes, including gene expression and apoptosis...
  2. ncbi request reprint Pharmacological effects of the lipidosterolic extract of Serenoa repens (Permixon) on rat prostate hyperplasia induced by hyperprolactinemia: comparison with finasteride
    F Van Coppenolle
    Laboratoire de Physiologie Cellulaire, USTL, INSERM EPI 9938, Villeneuve d Ascq, France
    Prostate 43:49-58. 2000
    ....
  3. ncbi request reprint Effects of hyperprolactinemia on rat prostate growth: evidence of androgeno-dependence
    F Van Coppenolle
    Laboratoire de Physiologie Cellulaire, Institut National de la Santé et de la Recherche Médicale INSERM EPI 9938, 59655 Villeneuve d Ascq, France
    Am J Physiol Endocrinol Metab 280:E120-9. 2001
    ..The in vivo model established here is a useful in vivo approach for studying the hormonal regulation of normal and pathological prostate development...
  4. ncbi request reprint Two types of store-operated Ca2+ channels with different activation modes and molecular origin in LNCaP human prostate cancer epithelial cells
    Fabien Vanden Abeele
    Laboratoire de Physiologie Cellulaire, INSERM EMI 0228, Universite des Sciences et Technologies de Lille, Bat SN3, 59655 Villeneuve d Ascq, France
    J Biol Chem 279:30326-37. 2004
    ..These results provide new insight into the nature of SOCs and their representation in the single cell type as well as permit reconciliation of current SOC activation hypotheses...
  5. ncbi request reprint Bcl-2-dependent modulation of Ca(2+) homeostasis and store-operated channels in prostate cancer cells
    Fabien Vanden Abeele
    Laboratoire de Physiologie Cellulaire, INSERM EPI 9938, Universite des Sciences et Technologies de Lille, Batiment SN3, 59655 Villeneuve d Ascq cedex, France
    Cancer Cell 1:169-79. 2002
    ..Our data therefore suggest the pivotal role of SOCs in apoptosis and cancer progression...
  6. ncbi request reprint Store-operated Ca2+ current in prostate cancer epithelial cells. Role of endogenous Ca2+ transporter type 1
    Fabien Vanden Abeele
    Laboratoire de Physiologie Cellulaire, INSERM EMI 0228, Batiment SN3, USTL, 59655 Villeneuve d Ascq, France
    J Biol Chem 278:15381-9. 2003
    ....
  7. pmc Cytoskeleton reorganization as an alternative mechanism of store-operated calcium entry control in neuroendocrine-differentiated cells
    Karine Vanoverberghe
    INSERM, U 1003, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villeneuve d Ascq, France
    PLoS ONE 7:e45615. 2012
    ..Our data suggest that targeting cytoskeleton-induced pathways of malignant cells together with SOCE-involved channels may prove a useful strategy in the treatment of advanced prostate cancer...
  8. pmc TRPV2 mediates adrenomedullin stimulation of prostate and urothelial cancer cell adhesion, migration and invasion
    Agathe Oulidi
    Inserm U1003, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villeneuve d Ascq, France
    PLoS ONE 8:e64885. 2013
    ..In this work we show that AM induces prostate and urothelial cancer cell migration and invasion through TRPV2 translocation to plasma membrane and the subsequent increase in resting calcium level...
  9. ncbi request reprint Complex modulation of the cold receptor TRPM8 by volatile anaesthetics and its role in complications of general anaesthesia
    Fabien Vanden Abeele
    Inserm U1003, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Laboratory of Excellence, Ion Channels Science and Therapeutics Université des Sciences et Technologies de Lille USTL, Villeneuve d Ascq, France
    J Cell Sci 126:4479-89. 2013
    ..Thus, we propose TRPM8 as a new clinical target for diminishing common and serious complications of general anaesthesia...
  10. doi request reprint Lysophospholipids stimulate prostate cancer cell migration via TRPV2 channel activation
    Michael Monet
    INSERM, U 800, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villeneuve d Ascq, F 59655 France Université des Sciences et Technologies de Lille USTL, Villeneuve d Ascq, F 59655, France
    Biochim Biophys Acta 1793:528-39. 2009
    ..Thus, for the first time, we have identified one of the natural regulators of TRPV2 channel, one of the mechanisms of TRPV2 activation and regulation, as well as its pathophysiological role in cancer...
  11. ncbi request reprint Ca2+ modulation of volume-regulated anion channels: evidence for colocalization with store-operated channels
    Loic Lemonnier
    Laboratoire de Physiologie Cellulaire, INSERM EPI 9938, Batiment SN3, USTL, 59655 Villeneuve d Ascq, France
    FASEB J 16:222-4. 2002
    ..Preferred access of SOC-transported Ca2+ to VRAC suggests colocalization of these channels in the cell membrane...
  12. doi request reprint Targeting apoptosis by the remodelling of calcium-transporting proteins in cancerogenesis
    Charlotte Dubois
    INSERM, U 1003, Equipe labellisée par la Ligue Nationale contre le cancer Laboratory of Excellence, Ion Channels Science and Therapeutics, Universite des Sciences et Technologies de Lille USTL, Villeneuve d Ascq, France
    FEBS J 280:5500-10. 2013
    ..We present the calcium-transporting proteins involved in the deregulation of apoptosis, and those chemotherapies that target actors in calcium-induced apoptosis. ..
  13. ncbi request reprint Role of endoplasmic reticulum calcium content in prostate cancer cell growth regulation by IGF and TNFalpha
    Sandrine Humez
    Laboratoire de Physiologie Cellulaire, INSERM EMI 0228, Universite des Sciences et Technologies de Lille, Villeneuve d Ascq, Cedex, France
    J Cell Physiol 201:201-13. 2004
    ..We thus identify [Ca(2+)](ER) and SERCA2b as a central targets for causing LNCaP PC cell life or death induced by growth modulators. Furthermore our results indicate that calcium pool contents can regulate cell growth...
  14. pmc Prolactin stimulates prostate cell proliferation by increasing endoplasmic reticulum content due to SERCA 2b over-expression
    Alexandre Crepin
    INSERM, U800, Laboratoire de Physiologie Cellulaire, Equipe Labellisee par la Ligue Contre le Cancer, Villeneuve d Ascq, F 59655 France
    Biochem J 401:49-55. 2007
    ..A small inter-fering RNA SERCA 2a/b, used to down-regulate endogenous SERCA 2b expression, reduced both PNT1A cell proliferation and [Ca2+]ER. We thus identify [Ca2+]ER and SERCA 2b as protagonists in PRL-induced proliferation...
  15. ncbi request reprint Ca2+-independent phospholipase A2-dependent gating of TRPM8 by lysophospholipids
    Fabien Vanden Abeele
    INSERM U800, Equipe Labellisee par la Ligue Contre le Cancer, Villeneuve d Ascq F 59650, France and Universite Lille 1, Villeneuve d Ascq F 59650, France
    J Biol Chem 281:40174-82. 2006
    ..This mechanism employs chemical rather than physical (temperature change) signaling and thus may be the main regulator of TRPM8 activation in organs not exposed to any essential temperature variations, as in the prostate gland...
  16. pmc Functional implications of calcium permeability of the channel formed by pannexin 1
    Fabien Vanden Abeele
    Institut National de la Sante et de la Recherche Medicale, U800, Equipe Labellisee par la Ligue Contre le Cancer, Universite des Sciences et Technologies de Lille, Villeneuve d Ascq Cedex, F 59655 France
    J Cell Biol 174:535-46. 2006
    ....