Bernard Uzzan

Summary

Country: France

Publications

  1. ncbi request reprint Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: a systematic review and meta-analysis
    Bernard Uzzan
    APHP Laboratoire de Pharmacologie Hormonologie, Hopital Avicenne, Bobigny, France
    Crit Care Med 34:1996-2003. 2006
  2. ncbi request reprint Effects of statins on bone mineral density: a meta-analysis of clinical studies
    Bernard Uzzan
    AP HP, Laboratoire de Pharmacologie, Hopital Avicenne, 125 route de Stalingrad, 93009 Bobigny, France
    Bone 40:1581-7. 2007
  3. doi request reprint Factitious increases in serum testosterone concentrations related to phenylbutazone therapy
    Bernard Uzzan
    Department of Pharmacology, AP HP, Hopital Avicenne, 125 route de Stalingrad, 93009 Bobigny, and Paris XIII University, France
    Fundam Clin Pharmacol 22:159-60. 2008
  4. doi request reprint Cyclooxygenase-2 expression and recurrence of colorectal adenomas: effect of aspirin chemoprevention
    Robert Benamouzig
    Department of Gastroenterology, AP HP, Hopital Avicenne, 125 route de Stalingrad, Bobigny, France
    Gut 59:622-9. 2010
  5. doi request reprint Prevention by daily soluble aspirin of colorectal adenoma recurrence: 4-year results of the APACC randomised trial
    Robert Benamouzig
    Department of Gastroenterology, AP HP, Avicenne Hospital, Paris 13 University, Bobigny, France
    Gut 61:255-61. 2012
  6. doi request reprint Does microsatellite instability predict the efficacy of adjuvant chemotherapy in colorectal cancer? A systematic review with meta-analysis
    Gaetan des Guetz
    Department of Oncology, APHP, Hopital Avicenne, Bobigny, France
    Eur J Cancer 45:1890-6. 2009
  7. doi request reprint Does delaying adjuvant chemotherapy after curative surgery for colorectal cancer impair survival? A meta-analysis
    Gaetan des Guetz
    AP HP, Department of Oncology, Avicenne Hospital, 125 route de Stalingrad, 93009 Bobigny, France
    Eur J Cancer 46:1049-55. 2010
  8. doi request reprint Comparison of the efficacy and safety of single-agent and doublet chemotherapy in advanced non-small cell lung cancer in the elderly: a meta-analysis
    Gaetan des Guetz
    Department of Oncology, AP HP, Avicenne Hospital, Paris XIII University, 125 route de Stalingrad, 93009 Bobigny, France
    Crit Rev Oncol Hematol 84:340-9. 2012
  9. doi request reprint Microsatellite instability: a predictive marker in metastatic colorectal cancer?
    Gaetan des Guetz
    Department of Oncology, APHP, Hopital Avicenne, 125 route de Stalingrad, 93009, Bobigny, France
    Target Oncol 4:57-62. 2009
  10. ncbi request reprint Microsatellite instability does not predict the efficacy of chemotherapy in metastatic colorectal cancer. A systematic review and meta-analysis
    Gaetan des Guetz
    Department of Oncology, APHP, Hopital Avicenne, 125 route de Stalingrad, 93009 Bobigny, France
    Anticancer Res 29:1615-20. 2009

Detail Information

Publications20

  1. ncbi request reprint Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: a systematic review and meta-analysis
    Bernard Uzzan
    APHP Laboratoire de Pharmacologie Hormonologie, Hopital Avicenne, Bobigny, France
    Crit Care Med 34:1996-2003. 2006
    ..To draw and compare the summary receiver operating characteristics curves for procalcitonin and C-reactive protein from the literature...
  2. ncbi request reprint Effects of statins on bone mineral density: a meta-analysis of clinical studies
    Bernard Uzzan
    AP HP, Laboratoire de Pharmacologie, Hopital Avicenne, 125 route de Stalingrad, 93009 Bobigny, France
    Bone 40:1581-7. 2007
    ..Amino-bisphosphonates share this effect. In vitro and in vivo, statins show convincing anabolic and anti-resorptive bone effects. However, in a clinical meta-analysis (MA), they did not prevent hip fractures...
  3. doi request reprint Factitious increases in serum testosterone concentrations related to phenylbutazone therapy
    Bernard Uzzan
    Department of Pharmacology, AP HP, Hopital Avicenne, 125 route de Stalingrad, 93009 Bobigny, and Paris XIII University, France
    Fundam Clin Pharmacol 22:159-60. 2008
    ..This interaction had been described previously only once. We discuss its potential mechanisms, based upon our experimental findings, and its clinical implications...
  4. doi request reprint Cyclooxygenase-2 expression and recurrence of colorectal adenomas: effect of aspirin chemoprevention
    Robert Benamouzig
    Department of Gastroenterology, AP HP, Hopital Avicenne, 125 route de Stalingrad, Bobigny, France
    Gut 59:622-9. 2010
    ..Low-dose aspirin reduces the incidence of colorectal cancer and recurrence of adenomas. Cyclooxygenase-2 (COX-2), one of its main target enzymes, is reportedly over-expressed in colorectal adenomas...
  5. doi request reprint Prevention by daily soluble aspirin of colorectal adenoma recurrence: 4-year results of the APACC randomised trial
    Robert Benamouzig
    Department of Gastroenterology, AP HP, Avicenne Hospital, Paris 13 University, Bobigny, France
    Gut 61:255-61. 2012
    ..In this study the results of daily intake of low-dose aspirin on polyp recurrence at 4-year follow-up are presented...
  6. doi request reprint Does microsatellite instability predict the efficacy of adjuvant chemotherapy in colorectal cancer? A systematic review with meta-analysis
    Gaetan des Guetz
    Department of Oncology, APHP, Hopital Avicenne, Bobigny, France
    Eur J Cancer 45:1890-6. 2009
    ..Microsatellite instability (MSI) status in predicting the efficacy of adjuvant chemotherapy in colorectal cancer remains controversial...
  7. doi request reprint Does delaying adjuvant chemotherapy after curative surgery for colorectal cancer impair survival? A meta-analysis
    Gaetan des Guetz
    AP HP, Department of Oncology, Avicenne Hospital, 125 route de Stalingrad, 93009 Bobigny, France
    Eur J Cancer 46:1049-55. 2010
    ..In stage III colorectal cancer (CRC), adjuvant chemotherapy (CT) is usually prescribed within two months after curative surgery. Whether or not delaying initiation of CT affects survival is still debated...
  8. doi request reprint Comparison of the efficacy and safety of single-agent and doublet chemotherapy in advanced non-small cell lung cancer in the elderly: a meta-analysis
    Gaetan des Guetz
    Department of Oncology, AP HP, Avicenne Hospital, Paris XIII University, 125 route de Stalingrad, 93009 Bobigny, France
    Crit Rev Oncol Hematol 84:340-9. 2012
    ..In patients with advanced non-small cell lung cancer (NSCLC) aged more than 70 years, the benefit-to-risk ratio of doublet chemotherapy vs single-agent is not established...
  9. doi request reprint Microsatellite instability: a predictive marker in metastatic colorectal cancer?
    Gaetan des Guetz
    Department of Oncology, APHP, Hopital Avicenne, 125 route de Stalingrad, 93009, Bobigny, France
    Target Oncol 4:57-62. 2009
    ..83 (95% confidence interval: 0.95; 0.65-1.05; p = 0.11). In conclusion, MSI status did not predict the effect of chemotherapy for metastatic CRC. Metastatic chemotherapy had a similar effect on both MSI-H or on MSS tumors...
  10. ncbi request reprint Microsatellite instability does not predict the efficacy of chemotherapy in metastatic colorectal cancer. A systematic review and meta-analysis
    Gaetan des Guetz
    Department of Oncology, APHP, Hopital Avicenne, 125 route de Stalingrad, 93009 Bobigny, France
    Anticancer Res 29:1615-20. 2009
    ..A previous meta-analysis (MA) in the adjuvant setting showed that MSI-high (H) status did not predict the efficacy of chemotherapy. The predictive value of MSI status on the effect of metastatic chemotherapy was investigated by MA...
  11. ncbi request reprint Serum procalcitonin in uncomplicated falciparum malaria: a preliminary study
    Bernard Uzzan
    Department of Pharmacology Hormonology, AP HP, Hopital Avicenne, Bobigny, France
    Travel Med Infect Dis 4:77-80. 2006
    ..Procalcitonin (PCT) has been found elevated in complicated forms of Plasmodium falciparum malaria. Its usefulness has almost never been assessed in uncomplicated falciparum malaria...
  12. doi request reprint Identification and chemoprevention in subjects at moderate risk of colorectal cancer
    Robert Benamouzig
    Department of Gastroenterology, AP HP, Avicenne Hospital, 125 rue de Stalingrad, Bobigny, France
    Best Pract Res Clin Gastroenterol 25:631-40. 2011
    ..In the present article, we will try to better define these particular situations and discuss the risk quantification and the expected chemoprevention contribution...
  13. ncbi request reprint Expression of ghrelin in fundus is increased after gastric banding in morbidly obese patients
    Bernard Uzzan
    Department of Pharmacology Hormonology, Hopital Avicenne, Assistance Publique Hopitaux de Paris, Bobigny, France
    Obes Surg 17:1159-64. 2007
    ..In this study, we assessed serum ghrelin level and gastric fundus expression before and 1 year after LAGB...
  14. ncbi request reprint Is sentinel lymph node mapping in colorectal cancer a future prognostic factor? A meta-analysis
    Gaetan des Guetz
    Department of Oncology, Hôpital Avicenne AP HP, 125 route de Stalingrad, Bobigny, France
    World J Surg 31:1304-12. 2007
    ..Understanding the cause of false-negative SLNs (9%) is a major issue to resolve before routinely using this technique in CRC management. The prognostic implication of micrometastases found in SLNs requires further evaluation...
  15. doi request reprint [Sarcoidosis: the involvement of anterior pituitary hormones is poorly recognized]
    Hélène Bihan
    Hopital Avicenne, Service d endocrinologie, diabétologie et maladies métaboliques, 93009 Bobigny, France
    Presse Med 41:e524-9. 2012
    ..The objective of this study was to evaluate the impact on the detection of hypothalamic-pituitary sarcoidosis in patients hospitalized for this condition in a lung disease sensibilized department...
  16. doi request reprint Cardiovascular toxicity of anti-angiogenic drugs
    Gaetan des Guetz
    Department of Medical Oncology, France and Paris XIII University, Bobighy
    Target Oncol 6:197-202. 2011
    ..In addition, their reversibility is not precisely known. This review aims to present and discuss the various cardiovascular toxicities of anti-angiogenic targeted therapies for cancer...
  17. ncbi request reprint Microvessel density as a prognostic factor in women with breast cancer: a systematic review of the literature and meta-analysis
    Bernard Uzzan
    Laboratoire de Pharmacologie Hôpital Avicenne, Bobigny, France
    Cancer Res 64:2941-55. 2004
    ..MVD was a significant although weak prognostic factor in women with breast cancer. Standardization of MVD assessment is needed...
  18. doi request reprint An anticancer strategic dilemma: to kill or to contain. The choice of the pharmaceutical industry in 2009
    Gerard Yves Perret
    Department of Pharmacology, AP HP, Avicenne Hospital, 125 route de Stalingrad, 93009 Bobigny, France
    Fundam Clin Pharmacol 25:283-95. 2011
    ..To obtain a dynamic view of the repartition of drugs between the killing strategy and the containment or mixed strategies, the present work should be renewed every 3-4 years...
  19. doi request reprint Efficacy of four insect repellents against mosquito bites: a double-blind randomized placebo-controlled field study in Senegal
    Bernard Uzzan
    Department of Pharmacology, AP HP, Avicenne Hospital, 93009 Bobigny, France
    Fundam Clin Pharmacol 23:589-94. 2009
    ..Such field studies should be required before approval of any newly developed repellent...
  20. ncbi request reprint Low dose aspirin, COX-inhibition and chemoprevention of colorectal cancer
    Robert Benamouzig
    Department of Gastro enterology, Hopital Avicenne, 125 rue de Stalingrad, 93009 Bobigny Cedex, France
    Curr Top Med Chem 5:493-503. 2005
    ..Four RCTs of the effect of aspirin on adenoma recurrence are available. Other trials are currently underway...