Research Topics
| Florence TubachSummaryCountry: France Publications
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Detail Information
Publications
Using patients' and rheumatologists' opinions to specify a short form of the WOMAC function subscaleF Tubach
Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hopitalier Bichat Claude Bernard, 75018 Paris, France
Ann Rheum Dis 64:75-9. 2005..Reducing the number of items of the subscale would enhance efficiency and compliance, particularly for use in clinical practice applications...
Natural history and prognostic indicators of sciaticaFlorence Tubach
INSERM U88, Hopital National de Saint Maurice, 94415 Saint Maurice Cedex, France
J Clin Epidemiol 57:174-9. 2004..Sciatica is thought to have a good clinical outcome, but in fact, its natural history is not well known...- Evaluation of clinically relevant states in patient reported outcomes in knee and hip osteoarthritis: the patient acceptable symptom stateF Tubach
Institut National de la Santé et de la Recherche Médicale E 0357, Département d Epidémiologie, Biostatistique et Recherche Clinique, 75018 Paris, France
Ann Rheum Dis 64:34-7. 2005..The patient acceptable symptom state (PASS) is the value beyond which patients can consider themselves well. This concept can help in interpreting results of clinical trials... - Evaluation of clinically relevant changes in patient reported outcomes in knee and hip osteoarthritis: the minimal clinically important improvementF Tubach
Institut National de la Sante et de la Recherche Medicale, Département d Epidémiologie, Biostatistique et Recherche Clinique, 75018 Paris, France
Ann Rheum Dis 64:29-33. 2005..In clinical trials, at the group level, results are usually reported as mean and standard deviation of the change in score, which is not meaningful for most readers... - Feeling good rather than feeling better matters more to patientsFlorence Tubach
Assistance Publique Hopitaux de Paris, Hopital Bichat, INSERM U738, Universite Paris 7 Denis Diderot, Paris, France
Arthritis Rheum 55:526-30. 2006.... 
High levels of anti-cyclic citrullinated peptide autoantibodies are associated with co-occurrence of pulmonary diseases with rheumatoid arthritisFleur Aubart
Service de Rhumatologie, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, 75018 Paris, France
J Rheumatol 38:979-82. 2011..To investigate whether levels of anti-cyclic citrullinated peptide antibodies (anti-CCP2) in patients with rheumatoid arthritis (RA) are associated with the co-occurrence of lung diseases...- A home-visiting intervention targeting determinants of infant mental health: the study protocol for the CAPEDP randomized controlled trial in FranceFlorence Tubach
AP HP, Hopital Bichat, Département d Epidémiologie et Recherche Clinique, 46 rue Henri Huchard, secteur Claude Bernard, 75877 Paris Cedex 18, Paris, France
BMC Public Health 12:648. 2012..abstract:.. - The variability in minimal clinically important difference and patient acceptable symptomatic state values did not have an impact on treatment effect estimatesFlorence Tubach
AP HP, Hopital Bichat, Département d Epidémiologie, Biostatistique et Recherche Clinique, Paris, France
J Clin Epidemiol 62:725-8. 2009..The objective was to investigate the influence of the choice of MCID and/or PASS values on the difference in success rate between arms... - Blinding was judged more difficult to achieve and maintain in nonpharmacologic than pharmacologic trialsIsabelle Boutron
INSERM EMI 03 57, Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Faculte Xavier Bichat, Universite Paris 7, France
J Clin Epidemiol 57:543-50. 2004..To compare the feasibility of blinding and the perceived risk of unblinding in trials evaluating pharmacologic (PT) and nonpharmacologic treatments (NPT) of hip or knee osteoarthritis... - Validation of a short form of the Western Ontario and McMaster Universities Osteoarthritis Index function subscale in hip and knee osteoarthritisGabriel Baron
AP HP, Hopital Bichat, Département d Eidémiologie, Biostatistique et Recherche Clinique, INSERM, U738, Paris, France
Arthritis Rheum 57:633-8. 2007..The goal of the present study was to validate this short form... - Surgical management of patients with Marfan syndrome: evolution throughout the yearsAlireza Samadi
Service de cardiologie, Centre de référence pour les syndromes de Marfan et apparentés, Hopital Bichat, Paris, France
Arch Cardiovasc Dis 105:84-90. 2012..To evaluate the evolution of surgical management in a large population of patients with Marfan syndrome... - Stability of the patient acceptable symptomatic state over time in outcome criteria in ankylosing spondylitisFlorence Tubach
Assistance Publique Hopitaux de Paris, Bichat Hospital, University Paris VII, INSERM U738, Paris, France
Arthritis Rheum 55:960-3. 2006..Our goal was to determine the PASS in main outcome criteria when assessing patients with ankylosing spondylitis (AS) and to evaluate whether the PASS is stable over time... - Evaluating fidelity in home-visiting programs a qualitative analysis of 1058 home visit case notes from 105 familiesThomas Saias
Laboratoire de Recherche, établissement public de santé Maison Blanche, Paris, France
PLoS ONE 7:e36915. 2012..This paper seeks to evaluate fidelity in a 27-month program addressing maternal and child health which took place in France between 2006 and 2011... - Minimal clinically important improvement and patient acceptable symptom state for subjective outcome measures in rheumatic disordersFlorence Tubach
Département d Epidémiologie, Biostatistique et Recherche Clinique, Hopital Bichat, Paris, France
J Rheumatol 34:1188-93. 2007..The purpose of this SIG at OMERACT 8 was to inform participants of the MCII and PASS concepts and to agree on MCII and PASS values for pain, patient global assessment, and functional impairment... - Aortic event rate in the Marfan population: a cohort studyGuillaume Jondeau
Centre de référence pour le syndrome de Marfan et apparentés, Hopital Bichat, 75018 Paris, France
Circulation 125:226-32. 2012..Optimal management, including timing of surgery, remains debated in Marfan syndrome because of a lack of data on aortic risk associated with this disease... - Minimal clinically important difference, low disease activity state, and patient acceptable symptom state: methodological issuesFlorence Tubach
, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat-Claude Bernard (AP-HP, INSERM U738, , Paris, France
J Rheumatol 32:2025-9. 2005..Threshold values for the MCID and LDAS should be determined according to data-driven and experts' opinions and approaches... - Intraarticular glucocorticoid injections in rapidly destructive hip osteoarthritisCaroline Villoutreix
Rheumatology B Department, Cochin Teaching Hospital, Assistance Publique des Hopitaux de Paris, René Descartes Paris V University, France
Joint Bone Spine 73:66-71. 2006.... - Lymphoma in patients treated with anti-TNF: results of the 3-year prospective French RATIO registryX Mariette
Hopital de Bicetre, Le Kremlin Bicetre, France
Ann Rheum Dis 69:400-8. 2010..To describe cases of lymphoma associated with anti-TNF therapy, identify risk factors, estimate the incidence and compare the risks for different anti-TNF agents... - Body mass index influences the response to infliximab in ankylosing spondylitisSebastien Ottaviani
Rheumatology Department, AP HP, Paris Diderot, Sorbonne Paris Cité University, Bichat Claude Bernard Hospital, 46 rue Henri Huchard, Paris, 75018, France
Arthritis Res Ther 14:R115. 2012..The aim of this study was to determine whether body mass index (BMI) affects response to infliximab (IFX) in ankylosing spondylitis (AS) patients... - Case-only designs in pharmacoepidemiology: a systematic reviewSandra Nordmann
Univ Paris Diderot, Sorbonne Paris Cité, UMR S 738 INSERM, UMR S 738, Paris, France
PLoS ONE 7:e49444. 2012.... - A new multimodal geriatric discharge-planning intervention to prevent emergency visits and rehospitalizations of older adults: the optimization of medication in AGEd multicenter randomized controlled trialSylvie Legrain
Geriatric Unit, l Assistance Publique Hôpitaux de Paris, Paris, France
J Am Geriatr Soc 59:2017-28. 2011..To determine whether a new multimodal comprehensive discharge-planning intervention would reduce emergency rehospitalizations or emergency department (ED) visits for very old inpatients... - Reporting of adherence to medication in recent randomized controlled trials of 6 chronic diseases: a systematic literature reviewLaure Gossec
AP HP, Rheumatology B Department, Cochin Hospital, 27 rue du Faubourg St Jacques, Paris 5 University, Paris, France
Am J Med Sci 334:248-54. 2007.... - Data capture by digital pen in clinical trials: a qualitative and quantitative studyCandice Estellat
INSERM U738, Paris, France
Contemp Clin Trials 29:314-23. 2008..To investigate the use of the digital pen (DP) system to collect data in a clinical trial. To assess the accuracy of the system in this setting... - Systematic review reveals heterogeneity in definition of a clinically relevant difference in painAdeline Ruyssen-Witrand
Paris 7 Denis Diderot University, Medecine Faculty, Paris, France
J Clin Epidemiol 64:463-70. 2011..To describe the pain decrease considered as clinically relevant when designing a trial and reporting its results... - Individualising the Western Ontario and McMaster Universities osteoarthritis index (WOMAC) function subscale: incorporating patient priorities for improvement to measure functional impairment in hip or knee osteoarthritisR Seror
AP HP, Hopital Bichat, Département d Epidémiologie, Biostatistique et Recherche Clinique, INSERM, U738, Paris, France
Ann Rheum Dis 67:494-9. 2008.... - Long-term follow-up of patients with tuberculosis as a complication of tumour necrosis factor (TNF)-alpha antagonist therapy: safe re-initiation of TNF-alpha blockers after appropriate anti-tuberculous treatmentB Denis
Universite Paris V, Hopital Necker Enfants Malades, Service des Maladies Infectieuses et Tropicales, Centre d Infectiologie Necker Pasteur, Paris, France
Clin Microbiol Infect 14:183-6. 2008..These data support the concept that TNF-alpha antagonists can be restarted in TB patients provided that adequate anti-TB treatment has been completed... - In vitro and in vivo evidence for the role of elastase shedding of CD163 in human atherothrombosisJuan Antonio Moreno
INSERM U, Paris, France
Eur Heart J 33:252-63. 2012..We analysed the relationship between CD163 solubilization and elastase in vitro, in macrophage culture, ex vivo in human atherosclerotic plaque samples, and in vivo, in plasma of patients with coronary artery disease... - Identification of periplakin as a new target for autoreactivity in idiopathic pulmonary fibrosisCamille Taillé
Service de Pneumologie, et Centre de Compétence des Maladies Pulmonaires Rares, Hopitaux de Paris, Paris, France
Am J Respir Crit Care Med 183:759-66. 2011..Injury to alveolar epithelial cells is central to the pathophysiology of idiopathic pulmonary fibrosis (IPF). An abnormal autoimmune response directed against antigens of the alveolar epithelium may contribute to the disease... - Neurologic complications and outcomes of infective endocarditis in critically ill patients: the ENDOcardite en REAnimation prospective multicenter studyRomain Sonneville
Service de Réanimation Médicale et des Maladies Infectieuses, Universite Paris 7 Denis Diderot, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris AP HP, Paris, France
Crit Care Med 39:1474-81. 2011..To describe the clinical spectrum of infective endocarditis in critically ill patients and assess the impact of neurologic complications on outcomes... - Delphi-consensus weights for ischemic and bleeding events to be included in a composite outcome for RCTs in thrombosis preventionAgnes Dechartres
UMR S 738, INSERM, Paris, France
PLoS ONE 6:e18461. 2011..To weight ischemic and bleeding events according to their severity to be used in a composite outcome in RCTs in the field of thrombosis prevention... - Rationale and design of a randomized clinical trial (Marfan Sartan) of angiotensin II receptor blocker therapy versus placebo in individuals with Marfan syndromeDelphine Detaint
Centre de référence pour le syndrome de Marfan et apparentés, Hopital Bichat, Paris, France
Arch Cardiovasc Dis 103:317-25. 2010.... - Methodological differences in clinical trials evaluating nonpharmacological and pharmacological treatments of hip and knee osteoarthritisIsabelle Boutron
Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard, Assistance Publique des Hopitaux de Paris, Faculte Xavier Bichat, Universite Paris VII, Paris, France
JAMA 290:1062-70. 2003.... - Predictive factors of early postoperative urinary retention in the postanesthesia care unitHawa Keita
Department of Anesthesiology and Intensive Care, Hospital Bichat Claude Bernard, Paris, France
Anesth Analg 101:592-6, table of contents. 2005..Age (>or=50 yr), amount of intraoperative fluid volume (>or=750 mL), and bladder volume on entry to PACU (>or=270 mL) were independent predictive factors for this complication... - Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trialLila Bouadma
Service de Reanimation Medicale, Universite Paris 7 Denis Diderot, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
Lancet 375:463-74. 2010..We aimed to establish the effectiveness of an algorithm based on the biomarker procalcitonin to reduce antibiotic exposure in this setting... - Methodology of therapeutic trials: lessons from the late evidence of the cardiovascular toxicity of some coxibsPhilippe Ravaud
INSERM U738, Département d Epidémiologie, de Biostatistique et de Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard, Faculte Xavier Bichat, Universite Paris 7, Paris Cedex 18, France
Joint Bone Spine 72:451-5. 2005..The advantages and drawbacks of observational studies and randomized trials are reviewed. Emphasis is put on the usefulness of independent steering committees for therapeutic trials and on the value of cumulative meta-analyses... - Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy: The three-year prospective French Research Axed on Tolerance of Biotherapies registryF Tubach
Universite Paris 7 Denis Diderot, INSERM U738, Assistance Publique Hopitaux de Paris AP HP, Hopital Bichat, Biostatistique et Recherche Clinique, Paris, France
Arthritis Rheum 60:1884-94. 2009..Our objective was to describe cases of TB associated with anti-TNF mAb therapy, identify risk factors, and estimate the incidence... - Measure of function in rheumatoid arthritis: individualised or classical scales?R Seror
Département d Epidémiologie, Biostatistique et Recherche Clinique, INSERM U738, Hopital Bichat, 46 rue Henri Huchard, 75018 Paris, France
Ann Rheum Dis 69:97-101. 2010..The Health Assessment Questionnaire Disability Index (HAQ-DI) is the most widely used measure of function in rheumatoid arthritis (RA)... - Effect of oseltamivir, zanamivir or oseltamivir-zanamivir combination treatments on transmission of influenza in householdsFabrice Carrat
APHP, Hopital Saint Antoine, Unité de santé publique, Paris, France
Antivir Ther 17:1085-90. 2012..The effectiveness of neuraminidase inhibitors to reduce transmission when used as treatment in influenza-infected patients remains debated... - Personal decision-making criteria related to seasonal and pandemic A(H1N1) influenza-vaccination acceptance among French healthcare workersLila Bouadma
Réanimation Médicale et des Maladies Infectieuses, Hôpital Bichat Claude Bernard Hôpitaux Universitaires Paris Nord Val de Seine, Assistance Publique Hopitaux de Paris, Paris, France
PLoS ONE 7:e38646. 2012..In France, this vaccination is free but administered on a voluntary basis. We investigated the factors influencing HCW influenza vaccination... - Role of the post-marketing authorisation studies in drug risk surveillance: specifications and methodologiesFlorence Tubach
Centre de Pharmaco épidémiologie, Paris, France
Therapie 66:355-62, 347-54. 2011..Concerning the specifications and the choice of methodology, only a general outline has been sketched in view of the complexity and diversity of drug risks situations... - Infant rhythms versus parental time: promoting parent-infant synchronyAntoine Guedeney
Hospital Bichat Claude Bernard, APHP, University Paris 7, Paris, France
J Physiol Paris 105:195-200. 2011.... - Anti-RNA polymerase III antibody prevalence and associated clinical manifestations in a large series of French patients with systemic sclerosis: a cross-sectional studyOlivier Meyer
Universite Paris 7 Denis Diderot, UFR de Medecine, APHP Hôpital Bichat, Service de Rhumatologie, Paris, France
J Rheumatol 37:125-30. 2010..To determine the prevalence of anti-RNA polymerase III autoantibodies in French patients with systemic sclerosis (SSc) and to identify the associated clinical manifestations... - Independent behavior of commensal flora for carriage of fluoroquinolone-resistant bacteria in patients at admissionVictoire de Lastours
Department of Internal Medicine, Hopital Beaujon, Assistance Publique Hopitaux de Paris, 100 Boulevard Général Leclerc, 92100 Clichy, France
Antimicrob Agents Chemother 54:5193-200. 2010..Consequences of environmental selective pressures vary in each commensal flora according to its local specificities (clinical trial NCT00520715 [http://clinicaltrials.gov/ct2/show/NCT00520715])... - Fear-avoidance beliefs about back pain in patients with acute LBPEmmanuel Coudeyre
Centre de Médecine Physique et Réadaptation Notre Dame, Avenue Joseph Claussat, Chamalières cedex, Paris, France
Clin J Pain 23:720-5. 2007..We aimed to assess fear-avoidance beliefs in patients with acute low back pain (LBP) and to identify features of patients and general practitioners (GPs) associated with patients' fear-avoidance beliefs... - The RATIO observatory: French registry of opportunistic infections, severe bacterial infections, and lymphomas complicating anti-TnFalpha therapyFlorence Tubach
INSERM U738, Bichat Teaching Hospital, Xavier Bichat School of Medicine, Paris 7 University, Paris, France
Joint Bone Spine 72:456-60. 2005.... - Emergence of Legionella pneumophila pneumonia in patients receiving tumor necrosis factor-alpha antagonistsF Tubach
Universite Paris 7, Faculte de Medecine, Paris, France
Clin Infect Dis 43:e95-100. 2006..Patients treated with tumor necrosis factor-alpha (TNF-alpha) antagonists have an increased risk of infection, but infection due to Legionella pneumophila has rarely been described in patients receiving such therapy... - Age-adapted morphine titration produces equivalent analgesia and adverse effects in younger and older patientsH Keita
Assistance Publique Hopitaux de Paris, Hospital Louis Mourier, Department of Anaesthesia, Colombes, France
Eur J Anaesthesiol 25:352-6. 2008..To determine the efficacy and safety of intravenous postoperative morphine titration in the elderly compared with younger patients... - Managing osteoarthritis of the knee: conclusions about use of NSAIDs are misleadingFlorence Tubach
BMJ 330:672; author reply 672-3. 2005 - General practitioners' fear-avoidance beliefs influence their management of patients with low back painEmmanuel Coudeyre
Hopital Cochin, AP-HP, Universite Paris 5, Physical Medicine and Rehabilitation, 27 rue du Faubourg Saint-Jacques, 75014 Paris, France
Pain 124:330-7. 2006..001) for chronic LBP. GPs' fear-avoidance beliefs about LBP negatively influence their following guidelines concerning physical and occupational activities for patients with LBP... - Spinal tuberculosis: a longitudinal study with clinical, laboratory, and imaging outcomesLaurence Le Page
APHP, , , 92110 Clichy, France
Semin Arthritis Rheum 36:124-9. 2006..CONCLUSIONS: Significant imaging abnormalities can persist after successful treatment of ST. These findings suggest that MRI need not be repeated in patients with clinical and laboratory improvement... - Liver fibrosis in women with chronic hepatitis C: evidence for the negative role of the menopause and steatosis and the potential benefit of hormone replacement therapyLiana Codes
Service d Hepatologie, University of Paris VII, AP HP Hôpital Beaujon, Clichy, France
Gut 56:390-5. 2007..The aim of this study was to evaluate the severity of chronic hepatitis C in women, in relation to the menopause, steatosis and hormone replacement therapy (HRT)...