M A LiuSummaryAffiliation: Transgene SA Country: France Publications
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Detail Information
Publications
DNA vaccines: a reviewM A Liu
Transgene, Strasbourg, France
J Intern Med 253:402-10. 2003..The breadth of applications for DNA vaccines thus ranges from prophylactic vaccines to immunotherapy for infectious diseases, cancer, and autoimmune and allergic diseases...
Reverse transcriptase-based DNA vaccines against drug-resistant HIV-1 tested in a mouse modelMaria G Isaguliants
Department of Virology, Swedish Institute for Infectious Disease Control, SE 171 82 Solna, Sweden
Vaccine 22:1810-9. 2004..Immunization of HLA-A(*)0201-transgenic mice with RT minigenes induced RT-specific cellular responses detected by interferon-gamma secretion. This documents first steps in creating therapeutic vaccine against drug-resistant HIV strains...
Gene-based vaccines and immunotherapeuticsMargaret Liu
Transgene, 11 rue de Molsheim, 67082 Strasbourg, France
Proc Natl Acad Sci U S A 101:14567-71. 2004..Both are encoded by a highly attenuated vaccinia virus vector [modified vaccinia Ankara (MVA)] and both are coexpressed with IL-2. Encouraging results seen in both of these programs are described...
Can successful vaccines teach us how to induce efficient protective immune responses?Paul Henri Lambert
Centre of Vaccinology, Department of Immunology Pathology, University of Geneva CMU, 1 rue Michel Servet, 1211 Geneva, Switzerland
Nat Med 11:S54-62. 2005....
Intracellular targeting of CEA results in Th1-type antibody responses following intradermal genetic vaccination by a needle-free jet injection deviceSusanne Johansson
Department of Microbiology and Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden
ScientificWorldJournal 7:987-99. 2007..In contrast, utilizing the DNA construct that resulted in intracellular targeting of CEA led to a reduced capacity to induce CEA-specific antibodies, but instead induced a Th1-biased immune response...
