Christine Tranchant

Summary

Country: France

Publications

  1. doi request reprint [Have centers of rare neurological diseases changed their practices and management of the hereditary cerebellar ataxias?]
    C Tranchant
    Centre de compétence des maladies neurologiques génétiques rares, Service de Neurologie, Hopital de Hautepierre, Avenue Moliere, 67100 Strasbourg, France
    Rev Neurol (Paris) 169:S23-7. 2013
  2. ncbi request reprint Phenotypic variability of aprataxin gene mutations
    C Tranchant
    Clinique Neurologique, Hopitaux Universitaires, CNRS, INSERM, Strasbourg France
    Neurology 60:868-70. 2003
  3. doi request reprint [Therapeutic strategy in myasthenia gravis]
    C Tranchant
    Service de Neurologie, Hopitaux Universitaires, Hopital Civil, 67091 Strasbourg Cedex
    Rev Neurol (Paris) 165:149-54. 2009
  4. ncbi request reprint [What is the role of other complementary examination in amyotrophic lateral sclerosis?]
    C Tranchant
    Departement de Neurologie, Hopitaux Universitaires, Strasbourg
    Rev Neurol (Paris) 162:4S50-4S56. 2006
  5. doi request reprint [Autosomal recessive cerebellar ataxias]
    Christine Tranchant
    Clinique Neurologique, Hopitaux Universitaires, F 67091 Strasbourg Cedex, France
    Presse Med 38:1852-9. 2009
  6. doi request reprint Use of SNP array analysis to identify a novel TRIM32 mutation in limb-girdle muscular dystrophy type 2H
    Mireille Cossee
    Laboratoire de Diagnostic Génétique, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Neuromuscul Disord 19:255-60. 2009
  7. doi request reprint Central nervous system abnormalities in patients with PMP22 gene mutations: a prospective study
    Jean Baptiste Chanson
    Department de Neurologie, Hopitaux Universitaires de Strasbourg, Hopital de Hautepierre, 1 Avenue Moliere, Strasbourg 67000, France
    J Neurol Neurosurg Psychiatry 84:392-7. 2013
  8. doi request reprint Muscle phosphorylase b kinase deficiency revisited
    Andoni Echaniz-Laguna
    Departement de Neurologie, Hopital Civil, BP426, 67091 Strasbourg, France
    Neuromuscul Disord 20:125-7. 2010
  9. doi request reprint POLG1 variations presenting as multiple sclerosis
    Andoni Echaniz-Laguna
    Departement de Neurologie, Hopital Civil, 67091 Strasbourg, France
    Arch Neurol 67:1140-3. 2010
  10. doi request reprint Myopathies in the elderly: a hospital-based study
    Andoni Echaniz-Laguna
    Departement de Neurologie, Hopital Civil, BP 426, 67091 Strasbourg, France
    Neuromuscul Disord 20:443-7. 2010

Detail Information

Publications55

  1. doi request reprint [Have centers of rare neurological diseases changed their practices and management of the hereditary cerebellar ataxias?]
    C Tranchant
    Centre de compétence des maladies neurologiques génétiques rares, Service de Neurologie, Hopital de Hautepierre, Avenue Moliere, 67100 Strasbourg, France
    Rev Neurol (Paris) 169:S23-7. 2013
    ..In the field of therapeutics, several studies are currently ongoing for Friedreich's ataxia...
  2. ncbi request reprint Phenotypic variability of aprataxin gene mutations
    C Tranchant
    Clinique Neurologique, Hopitaux Universitaires, CNRS, INSERM, Strasbourg France
    Neurology 60:868-70. 2003
    ..Patients 2 and 3 were French siblings and did not present with either OMA or hypoalbuminemia. They were compound heterozygous for the nonsense W279X mutation and a missense K197Q mutation...
  3. doi request reprint [Therapeutic strategy in myasthenia gravis]
    C Tranchant
    Service de Neurologie, Hopitaux Universitaires, Hopital Civil, 67091 Strasbourg Cedex
    Rev Neurol (Paris) 165:149-54. 2009
    ..The combination of corticosteroids and immunosuppressive agents are recommended early to spare corticosteroids. The treatment of myasthenia gravis should be modulated regularly (minimal doses for example)...
  4. ncbi request reprint [What is the role of other complementary examination in amyotrophic lateral sclerosis?]
    C Tranchant
    Departement de Neurologie, Hopitaux Universitaires, Strasbourg
    Rev Neurol (Paris) 162:4S50-4S56. 2006
    ....
  5. doi request reprint [Autosomal recessive cerebellar ataxias]
    Christine Tranchant
    Clinique Neurologique, Hopitaux Universitaires, F 67091 Strasbourg Cedex, France
    Presse Med 38:1852-9. 2009
    ..Biological tests should be: vitamin E, cholesterol, alpha-fetoprotein levels, acanthocytes, than phytanic acid, cholestanol, lysosomal enzymes. Numerous autosomal recessive cerebellar ataxia remain without etiology...
  6. doi request reprint Use of SNP array analysis to identify a novel TRIM32 mutation in limb-girdle muscular dystrophy type 2H
    Mireille Cossee
    Laboratoire de Diagnostic Génétique, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Neuromuscul Disord 19:255-60. 2009
    ..1753_1766dup14 (p.Ile590Leu fsX38). Together with two recently reported mutations, this novel mutation confirms that integrity of the C-terminal domain of TRIM32 is necessary for muscle maintenance...
  7. doi request reprint Central nervous system abnormalities in patients with PMP22 gene mutations: a prospective study
    Jean Baptiste Chanson
    Department de Neurologie, Hopitaux Universitaires de Strasbourg, Hopital de Hautepierre, 1 Avenue Moliere, Strasbourg 67000, France
    J Neurol Neurosurg Psychiatry 84:392-7. 2013
    ..Although mainly expressed in the PNS, PMP22 mRNA and protein are also present in the central nervous system (CNS)...
  8. doi request reprint Muscle phosphorylase b kinase deficiency revisited
    Andoni Echaniz-Laguna
    Departement de Neurologie, Hopital Civil, BP426, 67091 Strasbourg, France
    Neuromuscul Disord 20:125-7. 2010
    ..This report supports the concept that PHK deficiency is a mild metabolic myopathy and suggests that PHK mutations may interfere with normal brain function...
  9. doi request reprint POLG1 variations presenting as multiple sclerosis
    Andoni Echaniz-Laguna
    Departement de Neurologie, Hopital Civil, 67091 Strasbourg, France
    Arch Neurol 67:1140-3. 2010
    ..To describe 2 unrelated patients with novel variations in the POLG1 gene and features undistinguishable from multiple sclerosis, ie, optic neuritis, brain white matter hyperintense areas, and unmatched cerebrospinal fluid oligoclonal bands...
  10. doi request reprint Myopathies in the elderly: a hospital-based study
    Andoni Echaniz-Laguna
    Departement de Neurologie, Hopital Civil, BP 426, 67091 Strasbourg, France
    Neuromuscul Disord 20:443-7. 2010
    ..Clinicians should be aware of the existence of geriatric myopathies, an emerging entity with important implications for management, treatment, and genetic counseling...
  11. ncbi request reprint Novel Lamp-2 gene mutation and successful treatment with heart transplantation in a large family with Danon disease
    Andoni Echaniz-Laguna
    Departement de Neurologie, Hopital Civil, 1 Place de l Hopital, BP426, 67091 Strasbourg, France
    Muscle Nerve 33:393-7. 2006
    ..One patient was successfully treated by heart transplantation with more than 5-year follow-up. This study demonstrates that Danon disease is a frequently fatal condition that is potentially treatable with heart transplantation...
  12. doi request reprint A novel variation in the Twinkle linker region causing late-onset dementia
    Andoni Echaniz-Laguna
    Departement de Neurologie, Hopital Civil, BP 426, 67091, Strasbourg, France
    Neurogenetics 11:21-5. 2010
    ..These observations demonstrate that Twinkle variations in the linker domain alter cerebral function and further implicate disrupted mitochondrial DNA integrity in the pathogenesis of dementia...
  13. ncbi request reprint Subtle central and peripheral nervous system abnormalities in a family with centronuclear myopathy and a novel dynamin 2 gene mutation
    Andoni Echaniz-Laguna
    Departement de Neurologie, Hopital Civil de Strasbourg, 1 Place de l Hopital, BP426, 67091 Strasbourg, France
    Neuromuscul Disord 17:955-9. 2007
    ..This report extends the clinical knowledge of DNM2-centronuclear myopathy and shows that the role of DNM2 mutations in the central nervous system should be further studied...
  14. doi request reprint Ataxia with oculomotor apraxia type 2: clinical, biological and genotype/phenotype correlation study of a cohort of 90 patients
    M Anheim
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS, Universite de Strasbourg, INSERM, Illkirch, France
    Brain 132:2688-98. 2009
    ..001, P = 0.008 and P = 0.01, respectively). The lack of pyramidal signs in most patients may be explained by masking due to severe motor neuropathy...
  15. doi request reprint Clinical and molecular findings of ataxia with oculomotor apraxia type 2 in 4 families
    Mathieu Anheim
    Departement de Neurologie, Hopital Civil, 1 Place de l Hopital, 67091 Strasbourg, France
    Arch Neurol 65:958-62. 2008
    ....
  16. ncbi request reprint Muscular mitochondrial function in amyotrophic lateral sclerosis is progressively altered as the disease develops: a temporal study in man
    Andoni Echaniz-Laguna
    Departement de Neurologie, Hopital Civil de Strasbourg, 1 Place de l Hopital, BP426, 67091 Strasbourg, France
    Exp Neurol 198:25-30. 2006
    ..This temporal study demonstrates for the first time that mitochondrial function in SM in human SALS is progressively altered as the disease develops...
  17. doi request reprint SPG11 spastic paraplegia. A new cause of juvenile parkinsonism
    Mathieu Anheim
    Dépt de Neurologie, Hopital Civil, Centre Hospitalier Universitaire de Strasbourg 1, Place de l Hopital, 67000 Strasbourg, France
    J Neurol 256:104-8. 2009
    ..704_705delAT, p.H235RfsX12 homozygous mutation in SPG11. This report provides evidence that parkinsonism may initiate SPG11-linked HSP TCC and that SPG11 may cause juvenile parkinsonism...
  18. ncbi request reprint [Myasthenia gravis]
    Marie Celine Fleury
    Service de Neurologie, Hopitaux Universitaires, 67091 Strasbourg Cedex, France
    Rev Prat 58:2217-24. 2008
    ..During myasthenia crisis, intraveinous immune globulines or plasma exchanges can be used. Thymectomy is proposed in case of thymus abnormality...
  19. doi request reprint [Autosomal recessive spastic ataxia of Charlevoix-Saguenay: study of a family and review of the literature]
    M Anheim
    Clinique Neurologique, Hopital Civil, Centre Hospitalier Universitaire de Strasbourg, B P 426, 1, Place de l Hopital, 67091 Strasbourg Cedex, France
    Rev Neurol (Paris) 164:363-8. 2008
    ..We present a review of the literature on this rare disease mostly described in Quebec...
  20. ncbi request reprint [Acute myelitis and Lyme disease]
    F Blanc
    Departement de Neurologie, Hopitaux Universitaires de Strasbourg, Strasbourg
    Rev Neurol (Paris) 163:1039-47. 2007
    ..In the literature, simultaneous spinal MRI and cerebrospinal fluid (CSF) investigations are presented for only 8 cases. We describe here 3 cases of acute Lyme myelitis...
  21. ncbi request reprint Is clonidine growth hormone stimulation a good test to differentiate multiple system atrophy from idiopathic Parkinson's disease?
    C Tranchant
    Service des Maladies du Système Nerveux et du Muscle, Hopitaux Universitaires, 1 Place de l Hopital, 67091 Strasbourg, France christine
    J Neurol 247:853-6. 2000
    ..However, this response cannot be used as a diagnostic test because of its poor specificity...
  22. doi request reprint Effectiveness of anti-psychotics and related drugs in the huntington French-speaking group cohort
    Gaelle Desamericq
    Equipe 01, U955, INSERM, Creteil, France Faculté de Médecine, Universite Paris Est, Creteil, France Service de Pharmacologie Clinique, Hôpital H Mondor A Chenevier, AP HP, Creteil, France Département d Etudes Cognitives, Ecole Normale Superieure, Paris, France
    PLoS ONE 9:e85430. 2014
    ..Although differences in motor or behavioural profiles between patients according to the antipsychotics used were small, there were differences in drug effectiveness on the evolution of functional and cognitive scores. ..
  23. doi request reprint PRRT2 mutations: a major cause of paroxysmal kinesigenic dyskinesia in the European population
    Aurélie Méneret
    INSERM, UMRS 975, Hopital Pitie Salpetriere, Paris, France
    Neurology 79:170-4. 2012
    ..Mutations in the PRRT2 gene were recently identified in patients with PKD and ICCA. We studied the prevalence of PRRT2 mutations and characteristics of the patients in a European population of patients with PKD and ICCA...
  24. doi request reprint Early onset collagen VI myopathies: Genetic and clinical correlations
    Laura Brinas
    INSERM, U582, Paris, France
    Ann Neurol 68:511-20. 2010
    ..We extensively characterized, at the clinical, cellular, and molecular levels, 49 patients with onset in the first 2 years of life to investigate genotype-phenotype correlations...
  25. doi request reprint A genetic variation in the ADORA2A gene modifies age at onset in Huntington's disease
    Claire Marie Dhaenens
    INSERM, U837, Universite Lille Nord de France, USDL, IMPRT, Jean Pierre Aubert Research Centre, Lille, France
    Neurobiol Dis 35:474-6. 2009
    ..Patients harbouring T/T genotype have an earlier AAO of 3.8 years as compared to C/C genotype (p=0.02). Our data thus strengthens the pathophysiological role of A(2A) receptors in Huntington's disease...
  26. ncbi request reprint A family with early-onset and rapidly progressive X-linked spinal and bulbar muscular atrophy
    A Echaniz-Laguna
    Departement de Neurologie, Hopital Civil de Strasbourg, 1 Place de l Hopital, BP426, 67091 Strasbourg, France
    Neurology 64:1458-60. 2005
    ....
  27. ncbi request reprint An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus
    Matthieu Giraud
    INSERM, U580, 75015 Paris, France
    Nature 448:934-7. 2007
    ....
  28. doi request reprint Symptomatic paroxysmal dysarthria-ataxia in demyelinating diseases
    Christophe Marcel
    Departement de Neurologie, Hopital Civil de Strasbourg, 1 Place de l Hopital, BP426, 67091 Strasbourg, France
    J Neurol 257:1369-72. 2010
    ..The best clinical signs for distinguishing between symptomatic and primary PDA are adult onset and short (<1 min) episodes in the former. If these signs are present, brain MRI should be used to identify a cause of symptomatic PDA...
  29. ncbi request reprint A study of three patients with amyotrophic lateral sclerosis and a polyneuropathy resembling CIDP
    Andoni Echaniz-Laguna
    Departement de Neurologie, Hopital Civil de Strasbourg, 1 Place de l Hopital, BP426, 67091 Strasbourg, France
    Muscle Nerve 33:356-62. 2006
    ..This unusual combination may provide an important clue in elucidating the pathogenesis of ALS in some patients...
  30. ncbi request reprint [Subthalamic stimulation in a patient with multiple system atrophy: a clinicopathological report]
    V Talmant
    Departement de Neurologie, Hopital Civil, CHU, Strasbourg
    Rev Neurol (Paris) 162:363-70. 2006
    ..We report a patient with a clinical misdiagnosed MSA-P, later confirmed by neuropathological study, who was improved by DBS for one year...
  31. doi request reprint Myoclonus-dystonia: clinical and electrophysiologic pattern related to SGCE mutations
    E Roze
    Service de Neurologie, Hopital Saint Antoine, 184 rue du Faubourg Saint Antoine, 75571 Paris Cedex 12, France
    Neurology 70:1010-6. 2008
    ..To clarify the clinical and neurophysiologic spectrum of myoclonus-dystonia patients with mutations of the SGCE gene...
  32. ncbi request reprint [Motor and sensory deficit in the limbs]
    Mathieu Anheim
    Departement de Neurologie, Pôle tête et cou, Centre Hospitalo Universitaire, Hopital Civil, Strasbourg
    Rev Prat 57:1481-6; quiz 1486. 2007
  33. pmc Mutations of the FHL1 gene cause Emery-Dreifuss muscular dystrophy
    Lucie Gueneau
    INSERM, U974, Paris, France
    Am J Hum Genet 85:338-53. 2009
    ..In conclusion, FHL1 should be considered as a gene associated with the X-linked EDMD phenotype, as well as with hypertrophic cardiomyopathy...
  34. doi request reprint Follow-up study of the GIGYF2 gene in French families with Parkinson's disease
    Suzanne Lesage
    INSERM, UMR_S975 Formerly UMR_S679, Hopital de la Salpetriere, Paris, France
    Neurobiol Aging 31:1069-71; discussion 1072-4. 2010
    ..Together, these results do not support a major role of GIGYF2 in PD...
  35. doi request reprint [Precoce survey: a new self-assessment patient card for early detection and management of Parkinson disease fluctuations]
    J P Azulay
    Service de Neurologie, Hopital La Timone, 13005 Marseille, France
    Rev Neurol (Paris) 164:354-62. 2008
    ..The investigators have recognized the usefulness of this self-assessment in order to detect fluctuations in 81% of fluctuating patients, which lead them to modify the treatment in 76% of them...
  36. ncbi request reprint Relevance of the antibody index to diagnose Lyme neuroborreliosis among seropositive patients
    F Blanc
    Department of Neurology, University Hospital of Strasbourg, Louis Pasteur University, Strasbourg, France
    Neurology 69:953-8. 2007
    ..However, these studies included only typical clinical cases of meningitis or meningoradiculitis, and none had a control group with CSF anti-Borrelia antibodies...
  37. ncbi request reprint [Hemicontracture and facial myokimia as the first manifestation of multiple sclerosis]
    A Dupeyron
    , , Strasbourg, Cedex, France
    Rev Neurol (Paris) 157:315-7. 2001
    ..We report two cases of CMF as first manifestation of multiple sclerosis. Multiple sclerosis is the first diagnosis to suspect in young people with CFM...
  38. ncbi request reprint Mitochondrial respiratory chain function in skeletal muscle of ALS patients
    Andoni Echaniz-Laguna
    Service des Maladies du Système Nerveux et du Muscle, Clinique Neurologique, Hopital Civil de Strasbourg, 1 Place de l Hopital, BP 426, 67091 Strasbourg, France
    Ann Neurol 52:623-7. 2002
    ..min(-1). gm(-1)dw). This study shows an absence of large mitochondrial damage in skeletal muscle of patients with early-stage SALS, suggesting that mitochondrial dysfunction in the earlier stages of SALS is almost certainly not systemic...
  39. ncbi request reprint [Digestive tract disorders revealing mitochondrial cytopathy: MNGIE syndrome]
    F Chaury
    Service de Neurologie, Hopitaux Universitaires, 67091 Strasbourg Cedex, France
    Rev Neurol (Paris) 158:111-3. 2002
  40. ncbi request reprint [Ataxia associated with gluten sensitivity, myth or reality?]
    M Anheim
    Service des Maladies du Système Nerveux et du Muscle, Clinique Neurologique, Hopital Civil de Strasbourg, Strasbourg
    Rev Neurol (Paris) 162:214-21. 2006
    ..Gluten ataxia refers to the association of idiopathic ataxia despite exhaustive investigations with gluten sensitivity defined by anti-gliadin antibodies (AGA) presence in blood. This is a controversial concept...
  41. ncbi request reprint Disease expression of Lyme borreliosis in northeastern France
    D Lipsker
    Clinique Dermatologique, Strasbourg, France
    Eur J Clin Microbiol Infect Dis 20:225-30. 2001
    ..5%). The results show that the clinical expression of Lyme borreliosis in northeastern France is similar to that in other European countries but different from that in North America...
  42. doi request reprint Parkinson's disease-related LRRK2 G2019S mutation results from independent mutational events in humans
    Suzanne Lesage
    INSERM, UMR_S975 Formerly UMR_S679, Paris, France
    Hum Mol Genet 19:1998-2004. 2010
    ....
  43. ncbi request reprint [Vogt-Koyanagi-Harada syndrome]
    F Blanc
    Clinique Neurologique, Hopitaux Universitaires, Strasbourg
    Rev Neurol (Paris) 161:1079-90. 2005
    ..Vogt-Koyanagi-Harada syndrome is more frequent in Asia but is also described in Europe. We report three new non asiatic cases of this syndrome...
  44. doi request reprint Epidemiological, clinical, paraclinical and molecular study of a cohort of 102 patients affected with autosomal recessive progressive cerebellar ataxia from Alsace, Eastern France: implications for clinical management
    M Anheim
    Departement de Neurologie, Hopital Civil, Centre Hospitalier Universitaire de Strasbourg, 1, Place de l Hopital, 67000, Strasbourg, France
    Neurogenetics 11:1-12. 2010
    ..The strategic scheme is a useful tool for the diagnosis of ARCAs in clinical practice...
  45. ncbi request reprint [Acute relapse in Charcot-Marie-Tooth 1B neuropathy: can protein P0 behave like an autoantigen?]
    M Fleury
    Departement de Neurologie, Hopitaux Universitaires, Strasbourg
    Rev Neurol (Paris) 160:839-42. 2004
    ..The natural history of Charcot-Marie-Tooth neuropathy is marked by accentuated motor and sensitive deficits suggestive of acute polyradiculoneuritis or, more generally, chronic inflammatory demyelinizing polyneuropathy...
  46. ncbi request reprint [Hereditary neuropathy with liability to pressure palsy presenting with an acute inflammatory demyelinating polyneuropathy]
    B Degos
    Departement de Neurologie, Hopital Civil de Strasbourg, Strasbourg, France
    Rev Neurol (Paris) 160:1203-6. 2004
    ..It is usually caused by a 1.5 Mb deletion of the PMP22 gene (17p11.2)...
  47. doi request reprint A clinical, neuropsychological and olfactory evaluation of a large family with LRRK2 mutations
    Ebba Lohmann
    INSERM, UMR_S679 Neurologie and Thérapeutique Expérimentale, F 75013 Paris, France
    Parkinsonism Relat Disord 15:273-6. 2009
    ..We were therefore unable to identify a presymptomatic marker of LRRK2-related PD...
  48. pmc Epsilon sarcoglycan mutations and phenotype in French patients with myoclonic syndromes
    S Tezenas du Montcel
    Service de Biostatistique et Information Medicale, Hopital Pitie Salpetriere, AP HP, Paris, France
    J Med Genet 43:394-400. 2006
    ..Myoclonus dystonia syndrome (MDS) is an autosomal dominant movement disorder caused by mutations in the epsilon-sarcoglycan gene (SGCE) on chromosome 7q21...
  49. doi request reprint [American Academy of Neurology, Chicago, 12-18 April 2008]
    I Bonnaud
    Service de Neurologie 1, Hopital de la Salpetriere, 47, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Rev Neurol (Paris) 164:486-99. 2008
  50. ncbi request reprint [Report from the 57th Annual Meeting of the American Academy of Neurology]
    I Bonnaud
    Rev Neurol (Paris) 161:610-23. 2005
  51. ncbi request reprint Linkage of HLA to myasthenia gravis and genetic heterogeneity depending on anti-titin antibodies
    M Giraud
    INSERM U25, , Paris, France
    Neurology 57:1555-60. 2001
    ..Moreover, DR3 and DR7, or closely linked genes, have opposing effects on MG phenotypes. Nonthymomatous patients with ATA may be a pathogenetically distinct subset of MG patients...
  52. ncbi request reprint [A clinical, neurophysiological and molecular study of 12 patients from 4 families with spinal and bulbar muscular atrophy]
    A Echaniz-Laguna
    Departement de Neurologie, Hopital Civil de Strasbourg
    Rev Neurol (Paris) 161:437-44. 2005
    ..Material and method. We report the detailed phenotypic study in a series of 12 SBMA patients evaluated in four kindreds...
  53. ncbi request reprint [Report from the 56th annual meeting of the American Academy of Neurology]
    C Adam
    Rev Neurol (Paris) 160:606-22. 2004
  54. pmc Ataxic variant of Alzheimer's disease caused by Pro117Ala PSEN1 mutation
    M Anheim
    J Neurol Neurosurg Psychiatry 78:1414-5. 2007
  55. ncbi request reprint Absence of NR4A2 exon 1 mutations in 108 families with autosomal dominant Parkinson disease
    P Ibanez
    INSERM U289, Neurologie et Thérapeutique Expérimentale, Hopital de la Salpetriere, Paris, France
    Neurology 62:2133-4. 2004