Roselyne Tournaire

Summary

Country: France

Publications

  1. pmc A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor
    Roselyne Tournaire
    Institute of Signalling, Developmental Biology and Cancer, CNRS UMR 6543, Centre Antoine Lacassagne, 33 Avenue de Valombrose, 06189 Nice cedex, France
    EMBO Rep 5:262-7. 2004
  2. pmc Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis
    R Binétruy-Tournaire
    Universite Paris XIII, UFR Leonard de Vinci, UPRES 2360, Ciblage Fonctionnel des Tumeurs Solides, 74 rue Marcel Cachin, 93017 Bobigny Cedex, France
    EMBO J 19:1525-33. 2000
  3. doi request reprint The angiopoietin-2 gene of endothelial cells is up-regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA-2 and Ets-1
    Marie Pierre Simon
    Institute of Signaling, Developmental Biology and Cancer Research, CNRS UMR 6543, University of Nice, Centre A Lacassagne, Nice, France
    J Cell Physiol 217:809-18. 2008

Collaborators

Detail Information

Publications3

  1. pmc A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor
    Roselyne Tournaire
    Institute of Signalling, Developmental Biology and Cancer, CNRS UMR 6543, Centre Antoine Lacassagne, 33 Avenue de Valombrose, 06189 Nice cedex, France
    EMBO Rep 5:262-7. 2004
    ..It also represents a potent tool to dissect the molecular mechanisms involved in the Tie2 pathway...
  2. pmc Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis
    R Binétruy-Tournaire
    Universite Paris XIII, UFR Leonard de Vinci, UPRES 2360, Ciblage Fonctionnel des Tumeurs Solides, 74 rue Marcel Cachin, 93017 Bobigny Cedex, France
    EMBO J 19:1525-33. 2000
    ..Taken together, these data demonstrate that ATWLPPR is an effective antagonist of VEGF binding, and suggest that this peptide may be a potent inhibitor of tumor angiogenesis and metastasis...
  3. doi request reprint The angiopoietin-2 gene of endothelial cells is up-regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA-2 and Ets-1
    Marie Pierre Simon
    Institute of Signaling, Developmental Biology and Cancer Research, CNRS UMR 6543, University of Nice, Centre A Lacassagne, Nice, France
    J Cell Physiol 217:809-18. 2008
    ..In conclusion, our study provides new elements in favor of HIF involvement in Ang-2 hypoxic regulation and identifies Ets-1 and particularly GATA-2 as central factors in endothelial specific Ang-2 expression...