Research Topics
| Julie D ThompsonSummaryCountry: France Publications
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Detail Information
Publications
BAliBASE: a benchmark alignment database for the evaluation of multiple alignment programsJ D Thompson
Institut de Genetique et de Biologie Moleculaire et Cellulaire CNRS INSERM ULP, BP 163, 67404 Illkirch Cedex, France
Bioinformatics 15:87-8. 1999..AVAILABILITY: From http://www-igbmc. u-strasbg.fr/BioInfo/BAliBASE/index.html..
MAO: a Multiple Alignment Ontology for nucleic acid and protein sequencesJulie D Thompson
Institut de Génétique et deBiologie Moléculaire et Cellulaire 1 rue Laurent Fries, B P 10142, 67404 Illkirch Cedex, France
Nucleic Acids Res 33:4164-71. 2005....
MACSIMS: multiple alignment of complete sequences information management systemJulie D Thompson
Laboratoire de Biologie et Genomique Structurales, Institut de Genetique et de Biologie Moleculaire et Cellulaire, Illkirch, France
BMC Bioinformatics 7:318. 2006..Multiple alignments of complete sequences provide an ideal environment for the integration of this information in the context of the protein family...
Controversies in modern evolutionary biology: the imperative for error detection and quality controlFrancisco Prosdocimi
Department of Integrated Structural Biology, IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire CNRS INSERM Université de Strasbourg, 1 rue Laurent Fries, Illkirch, F 67404, France
BMC Genomics 13:5. 2012..Most gene sequences are predicted by bioinformatics programs and a number of quality issues have been raised, concerning DNA sequencing errors or badly predicted coding regions, particularly in eukaryotes...
A new protein linear motif benchmark for multiple sequence alignment softwareEmmanuel Perrodou
Institut de Genetique et de Biologie Moleculaire et Cellulaire, Department of Structural Biology and Genomics, F 67400 Illkirch, France
BMC Bioinformatics 9:213. 2008..As a consequence, poor motif alignment quality is hindering efforts to detect new LMs...
A comprehensive benchmark study of multiple sequence alignment methods: current challenges and future perspectivesJulie D Thompson
Département de Biologie Structurale et Génomique, IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS INSERM Université de Strasbourg, Illkirch, France
PLoS ONE 6:e18093. 2011..We then propose knowledge-enabled, dynamic solutions that will hopefully pave the way to enhanced alignment construction and exploitation in future evolutionary systems biology studies...
OrthoInspector: comprehensive orthology analysis and visual explorationBenjamin Linard
Laboratoire de bioinformatique et genomique integratives, Département de Biologie et Génomique Structurales CNRS INSERM UDS, Institut de Genetique et de Biologie Moleculaire et Cellulaire, 1 rue Laurent Fries, 67404, Illkirch, Cedex, France
BMC Bioinformatics 12:11. 2011..Various methods have been developed based on either simple blast all-versus-all pairwise comparisons and/or time-consuming phylogenetic tree analyses...
Issues in bioinformatics benchmarking: the case study of multiple sequence alignmentMohamed Radhouene Aniba
Department of Structural Biology and Genomics, Institut de Genetique et de Biologie Moleculaire et Cellulaire, The Centre National de la Recherche Scientifique, UMR7104, F 67400 Illkirch and Université de Strasbourg, F 67000 Strasbourg, France
Nucleic Acids Res 38:7353-63. 2010..Finally, we propose directions for future developments that will ensure that the bioinformatics benchmarks correspond to the challenges posed by the high throughput data...
PipeAlign: A new toolkit for protein family analysisFrederic Plewniak
Laboratoire de Biologie et Genomique Structurales, Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP, BP 10142, 67404 Illkirch Cedex, France
Nucleic Acids Res 31:3829-32. 2003..PipeAlign is available at http://igbmc.u-strasbg.fr/PipeAlign/...
KD4v: Comprehensible Knowledge Discovery System for Missense VariantTien Dao Luu
Laboratoire de bioinformatique et genomique integratives, Institut de Genetique et de Biologie Moleculaire et Cellulaire, 67404 Illkirch, France
Nucleic Acids Res 40:W71-5. 2012..These rules are interpretable by non-expert humans and are used to accurately predict the deleterious/neutral status of an unknown mutation. The web server is available at http://decrypthon.igbmc.fr/kd4v...
LEON: multiple aLignment Evaluation Of NeighboursJulie D Thompson
Laboratoire de Biologie et Genomique Structurales, , CNRS/INSERM/ULP, BP 163, 67404 Illkirch Cedex, France
Nucleic Acids Res 32:1298-307. 2004....
Comparison of eukaryotic phylogenetic profiling approaches using species tree aware methodsValentin Ruano-Rubio
Laboratoire de Biologie et Génomique Intégrative, Département de Biologie et Génomique Structurales, Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM UdS, Illkirch, France
BMC Bioinformatics 10:383. 2009....
EvoluCode: Evolutionary Barcodes as a Unifying Framework for Multilevel Evolutionary DataBenjamin Linard
Laboratoire de bioinformatique et genomique integratives, Institut de Génétique et de Biologie Moléculaire et Cellulaire CNRS INSERM UDS, Illkirch, France
Evol Bioinform Online 8:61-77. 2012..A database containing all EvoluCode data is available at: http://lbgi.igbmc.fr/barcodes...
